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2019 1

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GABA 1

SOD 1

cerebral ischemia 1

leonurine 1

neuroprotection 1

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Leonurine protects ischemia-induced brain injury via modulating SOD, MDA and GABA levels

Shilei ZHENG, Jingru ZHU, Jiao LI, Shuang ZHANG, Yunfei MA

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 2,   Pages 197-205 doi: 10.15302/J-FASE-2018245

Abstract:

The present study was designed to investigate the protective effects of leonurine, a compound purifiedWe found leonurine significantly improve the general activity of rats in an open-field test, which wasMoreover, serum SOD activity was significantly greater, MDA level lower in the leonurine group as comparedIn addition, GABA content in the cerebral cortex was significantly greater in high-dose leonurine groupand anti-excitotoxicity effects by targeting GABA and leonurine might become a useful adjuvant neuroprotective

Keywords: cerebral ischemia     GABA     neuroprotection     leonurine     SOD    

Title Author Date Type Operation

Leonurine protects ischemia-induced brain injury via modulating SOD, MDA and GABA levels

Shilei ZHENG, Jingru ZHU, Jiao LI, Shuang ZHANG, Yunfei MA

Journal Article