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2020 1

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CCB 1

Golgi apparatus 1

NIR imaging 1

cyclooxygenase-2 1

nile blue 1

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Near-infrared fluorescent probe for fast track of cyclooxygenase-2 in Golgi apparatus in cancer cells

Bhaskar Gurram, Miao Li, Jiangli Fan, Jingyun Wang, Xiaojun Peng

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 1,   Pages 41-52 doi: 10.1007/s11705-019-1796-1

Abstract: probe NB-C6-CCB for the detection of COX-2.NB-C6-CCB displays strong fluorescence with the emission peak centered at near-infrared wavelength (700Importantly, NB-C6-CCB can discriminate cancer cells (MCF-7) fluorescence intensity from normal onesThe competitive analysis (with CCB) and Native-PAGE analysis confirmed that NB-C6-CCB shows selectivedue to pretreatment of CCB with different concentrations, indicating that the NB-C6-CCB is a precise

Keywords： cyclooxygenase-2     nile blue     CCB     Golgi apparatus     NIR imaging    

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Near-infrared fluorescent probe for fast track of cyclooxygenase-2 in Golgi apparatus in cancer cells

Bhaskar Gurram, Miao Li, Jiangli Fan, Jingyun Wang, Xiaojun Peng

Journal Article