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Near-infrared fluorescent probe for fast track of cyclooxygenase-2 in Golgi apparatus in cancer cells

Bhaskar Gurram, Miao Li, Jiangli Fan, Jingyun Wang, Xiaojun Peng

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 1,   Pages 41-52 doi: 10.1007/s11705-019-1796-1

Abstract: Cyclooxygenase-2 (COX-2) has been used as an excellent traceable biomarker, and exists maximally in GolgiCelecoxib (CCB) is a selective inhibitor for COX-2, and has been used as one of non-steroidal anti-inflammatory) with CCB via a six-carbon linkage to form a fluorescence probe NB-C6-CCB for the detection of COX-2.CCB) and Native-PAGE analysis confirmed that NB-C6-CCB shows selective binding affinity towards COX-2different concentrations, indicating that the NB-C6-CCB is a precise or sensitive probe for the COX-2.

Keywords： cyclooxygenase-2     nile blue     CCB     Golgi apparatus     NIR imaging    

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Cyclooxygenase-2 gene-1195G/A genotype is associated with the risk of HBV-induced HCC: A case-control

Li-Feng LIU MD, PhD, Qiong CHEN MD, PhD, Ying CHANG MD, PhD, Ju-Sheng LIN MD, PhD, Jin-Liang ZHANG MM,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 90-95 doi: 10.1007/s11684-010-0021-x

Abstract: This study aimed to identify functional single nucleotide polymorphisms in the cyclooxygenase-2 gene

Keywords： cyclooxygenase-2 gene     single nucleotide polymorphisms     susceptibility     primary hepatocellular carcinoma    

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metastasis is related to the epithelial-mesenchymal transition and expressions of VEGF, MMP-9, and COX-2

Lihui WANG, Lianhong LI, Shen LV, Shujun FAN, Li ZHAN, Bo WANG, Zhong ZHANG

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 164-170 doi: 10.1007/s11684-009-0038-1

Abstract: N-cadherin (N-Cad), vascular endothelial cell growth factor (VEGF), matrix metalloproteinase-9 (MMP-9), cyclooxygenase-2-2 (COX-2), and CD34 were examined in 74 cases of breast cancer, including 39 cases with lymph node metastasisThe expressions of N-Cad, VEGF, MMP-9, and COX-2 in cases with lymph node metastasis were significantlyThere was a statistical difference in the expression of COX-2 protein between histological grade I andThis study indicates that EMT and expressions of VEGF, MMP-9 and COX-2, and MVD value are strongly correlated

Keywords： epithelial-mesenchymal transition     vascular endothelial cell growth factor     matrix metalloproteinase-9     cyclooxygenase-2-2     higher microvascular density     breast cancer    

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Efficacy and safety of perioperative parecoxib for acute postoperative pain treatment in children: a meta-analysis

Xueshan Bu,Lei Yang,Yunxia Zuo

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 496-507 doi: 10.1007/s11684-015-0414-y

Abstract: with children who received placebo treatment, those who received parecoxib demonstrated lower early (2Similarly, children who received parecoxib had lower early (2 h) and later (12 h) postoperative pain

Keywords： NSAID     cyclooxygenase 2 inhibitor     child     pain     postoperative     opioid     placebo    

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第三届环境、工业和能源工程国际会议(EI2E 2019)

Conference Date: 19 Sep 2019

Conference Place: 宁夏银川

Administered by: APISE

第四届设计、机械和材料工程国际会议(D2ME 2019)

Conference Date: 26 Sep 2019

Conference Place: 釜山，韩国

Administered by: HKSME

第四届设计、机械和材料工程国际会议(D2ME 2019)

Conference Date: 26 Sep 2019

Conference Place: 釜山，韩国

Administered by: HKSME

第2届智能医疗与图像处理国际会议(IMIP 2020)

Conference Date: 23 Apr 2020

Conference Place: 天津

Administered by: IMIP 2020

Title Author Date Type Operation

Near-infrared fluorescent probe for fast track of cyclooxygenase-2 in Golgi apparatus in cancer cells

Bhaskar Gurram, Miao Li, Jiangli Fan, Jingyun Wang, Xiaojun Peng

Journal Article

Cyclooxygenase-2 gene-1195G/A genotype is associated with the risk of HBV-induced HCC: A case-control

Li-Feng LIU MD, PhD, Qiong CHEN MD, PhD, Ying CHANG MD, PhD, Ju-Sheng LIN MD, PhD, Jin-Liang ZHANG MM,

Journal Article

metastasis is related to the epithelial-mesenchymal transition and expressions of VEGF, MMP-9, and COX-2

Lihui WANG, Lianhong LI, Shen LV, Shujun FAN, Li ZHAN, Bo WANG, Zhong ZHANG

Journal Article

Efficacy and safety of perioperative parecoxib for acute postoperative pain treatment in children: a meta-analysis

Xueshan Bu,Lei Yang,Yunxia Zuo

Journal Article

第三届环境、工业和能源工程国际会议(EI2E 2019)

19 Sep 2019

Conference Information

第四届设计、机械和材料工程国际会议(D2ME 2019)

26 Sep 2019

Conference Information

Xiao Yonghong: Co-evolution of Clinical Highly Resistant and Highly Toxic Pathogens (2023-2-22)

10 Mar 2023

Conference Videos

第四届设计、机械和材料工程国际会议(D2ME 2019)

26 Sep 2019

Conference Information

Between Physical Activity, Sedentary Behavior and Cardiovascular Disease risk in Patients with Type 2Diabetes: MlDiab Study (2023-2-21)

2 Mar 2023

Conference Videos

Shenshizhao: Large Span Structure (2018-6-2)

22 Apr 2021

Conference Videos

Jian Li：iScience and Interdisciplinary Research (2020-4-2)

18 Apr 2022

Conference Videos

Jin Yong: Expansion of Chemical Reaction Scale (2018-6-2)

22 Apr 2021

Conference Videos

Academician Xu Mi Interpretation of China's Nuclear Energy (2018-6-2)

22 Apr 2021

Conference Videos

Sun Jinsheng: Oil and Gas Exploitation in China (2018-6-2)

15 Apr 2021

Conference Videos

第2届智能医疗与图像处理国际会议(IMIP 2020)

23 Apr 2020

Conference Information