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Journal Article 1

Year

2018 1

Keywords

NCOU1 1

NTR 1

fragmentation 1

nitrobenzyl-umbelliferone 1

nitroreductase 1

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A simple umbelliferone based fluorescent probe for the detection of nitroreductase

Adam C. Sedgwick, Alex Hayden, Barry Hill, Steven D. Bull, Robert B. P. Elmes, Tony D. James

Frontiers of Chemical Science and Engineering 2018, Volume 12, Issue 2,   Pages 311-314 doi: 10.1007/s11705-017-1697-0

Abstract: A simple nitrobenzyl-umbelliferone (NCOU1) was synthesised containing a nitroreductase (NTR) triggerresulted in the fragmentation of the parent molecule and release of the highly emissive fluorophore umbelliferone

Keywords： fragmentation     NCOU1     NTR     nitroreductase     nitrobenzyl-umbelliferone    

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A simple umbelliferone based fluorescent probe for the detection of nitroreductase

Adam C. Sedgwick, Alex Hayden, Barry Hill, Steven D. Bull, Robert B. P. Elmes, Tony D. James

Journal Article