2020-10-30 , Volume 6 Issue 10

Cover illustration

  •  

    This cover image shows the sequences encoding the spike protein of SARS-CoV-2, the causal agent of COVID-19. COVID-19 has caused a large-scale global outbreak and has become a major public health issue. As an essential part in the viral entry of SARS-CoV-2, the spike protein is a target for vaccine and drug development. Researchers have designed a recombinant adenovirus type-5 (Ad5)-vectored COVID-19 vaccine based on spike protein genes, which encodes the full spike protein. After a single immunization in phases I and II of human clinical trials, the Ad5-vectored COVID-19 vaccine has demonstrated favorable safety and immunogenicity profiles and has been shown to induce rapid humoral and T-cell responses. The results from the published clinical studies are promising and pave the way for efficacy trials.

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    Editorial
  • Editorial for the Special Issue on COVID-19
    Xiaohong Li , Chen Wang , Boli Zhang , Baofeng Yang

    Nowadays, there has been a growing trend in the field of high-energy physics (HEP), in both its experimental and phenomenological studies, to incorporate machine learning (ML) and its specialized branch, deep learning (DL). This review paper provides a thorough illustration of these applications using different ML and DL approaches. The first part of the paper examines the basics of various particle physics types and establishes guidelines for assessing particle physics alongside the available learning models. Next, a detailed classification is provided for representing Jets that are reconstructed in high-energy collisions, mainly in proton-proton collisions at well-defined beam energies. This section covers various datasets, preprocessing techniques, and feature extraction and selection methods. The presented techniques can be applied to future hadron−hadron colliders (HHC), such as the high-luminosity LHC (HL-LHC) and the future circular collider−hadron−hadron (FCC-hh). The authors then explore several AI techniques analyses designed specifically for both image and point-cloud (PC) data in HEP. Additionally, a closer look is taken at the classification associated with Jet tagging in hadron collisions. In this review, various state-of-the-art (SOTA) techniques in ML and DL are examined, with a focus on their implications for HEP demands. More precisely, this discussion addresses various applications in extensive detail, such as Jet tagging, Jet tracking, and particle classification. The review concludes with an analysis of the current state of HEP using DL methodologies. It highlights the challenges and potential areas for future research, which are illustrated for each application.

  • News & Highlights
  • COVID-19 Fight Enlists Digital Technology: Tracking an Elusive Foe
    Mitch Leslie

    Nowadays, there has been a growing trend in the field of high-energy physics (HEP), in both its experimental and phenomenological studies, to incorporate machine learning (ML) and its specialized branch, deep learning (DL). This review paper provides a thorough illustration of these applications using different ML and DL approaches. The first part of the paper examines the basics of various particle physics types and establishes guidelines for assessing particle physics alongside the available learning models. Next, a detailed classification is provided for representing Jets that are reconstructed in high-energy collisions, mainly in proton-proton collisions at well-defined beam energies. This section covers various datasets, preprocessing techniques, and feature extraction and selection methods. The presented techniques can be applied to future hadron−hadron colliders (HHC), such as the high-luminosity LHC (HL-LHC) and the future circular collider−hadron−hadron (FCC-hh). The authors then explore several AI techniques analyses designed specifically for both image and point-cloud (PC) data in HEP. Additionally, a closer look is taken at the classification associated with Jet tagging in hadron collisions. In this review, various state-of-the-art (SOTA) techniques in ML and DL are examined, with a focus on their implications for HEP demands. More precisely, this discussion addresses various applications in extensive detail, such as Jet tagging, Jet tracking, and particle classification. The review concludes with an analysis of the current state of HEP using DL methodologies. It highlights the challenges and potential areas for future research, which are illustrated for each application.

  • COVID-19 Fight Enlists Digital Technology: Contact Tracing Apps
    Mitch Leslie

    Nowadays, there has been a growing trend in the field of high-energy physics (HEP), in both its experimental and phenomenological studies, to incorporate machine learning (ML) and its specialized branch, deep learning (DL). This review paper provides a thorough illustration of these applications using different ML and DL approaches. The first part of the paper examines the basics of various particle physics types and establishes guidelines for assessing particle physics alongside the available learning models. Next, a detailed classification is provided for representing Jets that are reconstructed in high-energy collisions, mainly in proton-proton collisions at well-defined beam energies. This section covers various datasets, preprocessing techniques, and feature extraction and selection methods. The presented techniques can be applied to future hadron−hadron colliders (HHC), such as the high-luminosity LHC (HL-LHC) and the future circular collider−hadron−hadron (FCC-hh). The authors then explore several AI techniques analyses designed specifically for both image and point-cloud (PC) data in HEP. Additionally, a closer look is taken at the classification associated with Jet tagging in hadron collisions. In this review, various state-of-the-art (SOTA) techniques in ML and DL are examined, with a focus on their implications for HEP demands. More precisely, this discussion addresses various applications in extensive detail, such as Jet tagging, Jet tracking, and particle classification. The review concludes with an analysis of the current state of HEP using DL methodologies. It highlights the challenges and potential areas for future research, which are illustrated for each application.

  • Views & Comments
  • Challenges in the Development of a Vaccine Against COVID-19
    Wei Chen , Feng-Cai Zhu

    Nowadays, there has been a growing trend in the field of high-energy physics (HEP), in both its experimental and phenomenological studies, to incorporate machine learning (ML) and its specialized branch, deep learning (DL). This review paper provides a thorough illustration of these applications using different ML and DL approaches. The first part of the paper examines the basics of various particle physics types and establishes guidelines for assessing particle physics alongside the available learning models. Next, a detailed classification is provided for representing Jets that are reconstructed in high-energy collisions, mainly in proton-proton collisions at well-defined beam energies. This section covers various datasets, preprocessing techniques, and feature extraction and selection methods. The presented techniques can be applied to future hadron−hadron colliders (HHC), such as the high-luminosity LHC (HL-LHC) and the future circular collider−hadron−hadron (FCC-hh). The authors then explore several AI techniques analyses designed specifically for both image and point-cloud (PC) data in HEP. Additionally, a closer look is taken at the classification associated with Jet tagging in hadron collisions. In this review, various state-of-the-art (SOTA) techniques in ML and DL are examined, with a focus on their implications for HEP demands. More precisely, this discussion addresses various applications in extensive detail, such as Jet tagging, Jet tracking, and particle classification. The review concludes with an analysis of the current state of HEP using DL methodologies. It highlights the challenges and potential areas for future research, which are illustrated for each application.

  • Ethical Reflection on the Emergency Engineering Management of COVID-19 Epidemic Prevention and Control
    Dongping Fang , Wenqi Li , Hengli Zhang , He Liu

    Nowadays, there has been a growing trend in the field of high-energy physics (HEP), in both its experimental and phenomenological studies, to incorporate machine learning (ML) and its specialized branch, deep learning (DL). This review paper provides a thorough illustration of these applications using different ML and DL approaches. The first part of the paper examines the basics of various particle physics types and establishes guidelines for assessing particle physics alongside the available learning models. Next, a detailed classification is provided for representing Jets that are reconstructed in high-energy collisions, mainly in proton-proton collisions at well-defined beam energies. This section covers various datasets, preprocessing techniques, and feature extraction and selection methods. The presented techniques can be applied to future hadron−hadron colliders (HHC), such as the high-luminosity LHC (HL-LHC) and the future circular collider−hadron−hadron (FCC-hh). The authors then explore several AI techniques analyses designed specifically for both image and point-cloud (PC) data in HEP. Additionally, a closer look is taken at the classification associated with Jet tagging in hadron collisions. In this review, various state-of-the-art (SOTA) techniques in ML and DL are examined, with a focus on their implications for HEP demands. More precisely, this discussion addresses various applications in extensive detail, such as Jet tagging, Jet tracking, and particle classification. The review concludes with an analysis of the current state of HEP using DL methodologies. It highlights the challenges and potential areas for future research, which are illustrated for each application.

  • Mesenchymal Stem Cells Represent a Therapeutic Option for Coronavirus Disease 2019-Related Acute Respiratory Distress Syndrome
    Xuan Zhao , Yi Zhang

    Nowadays, there has been a growing trend in the field of high-energy physics (HEP), in both its experimental and phenomenological studies, to incorporate machine learning (ML) and its specialized branch, deep learning (DL). This review paper provides a thorough illustration of these applications using different ML and DL approaches. The first part of the paper examines the basics of various particle physics types and establishes guidelines for assessing particle physics alongside the available learning models. Next, a detailed classification is provided for representing Jets that are reconstructed in high-energy collisions, mainly in proton-proton collisions at well-defined beam energies. This section covers various datasets, preprocessing techniques, and feature extraction and selection methods. The presented techniques can be applied to future hadron−hadron colliders (HHC), such as the high-luminosity LHC (HL-LHC) and the future circular collider−hadron−hadron (FCC-hh). The authors then explore several AI techniques analyses designed specifically for both image and point-cloud (PC) data in HEP. Additionally, a closer look is taken at the classification associated with Jet tagging in hadron collisions. In this review, various state-of-the-art (SOTA) techniques in ML and DL are examined, with a focus on their implications for HEP demands. More precisely, this discussion addresses various applications in extensive detail, such as Jet tagging, Jet tracking, and particle classification. The review concludes with an analysis of the current state of HEP using DL methodologies. It highlights the challenges and potential areas for future research, which are illustrated for each application.

  • Research
  • Review
    Strategies and Advances in Combating COVID-19 in China
    Wei Liu , Wei-Jie Guan , Nan-Shan Zhong

    Nowadays, there has been a growing trend in the field of high-energy physics (HEP), in both its experimental and phenomenological studies, to incorporate machine learning (ML) and its specialized branch, deep learning (DL). This review paper provides a thorough illustration of these applications using different ML and DL approaches. The first part of the paper examines the basics of various particle physics types and establishes guidelines for assessing particle physics alongside the available learning models. Next, a detailed classification is provided for representing Jets that are reconstructed in high-energy collisions, mainly in proton-proton collisions at well-defined beam energies. This section covers various datasets, preprocessing techniques, and feature extraction and selection methods. The presented techniques can be applied to future hadron−hadron colliders (HHC), such as the high-luminosity LHC (HL-LHC) and the future circular collider−hadron−hadron (FCC-hh). The authors then explore several AI techniques analyses designed specifically for both image and point-cloud (PC) data in HEP. Additionally, a closer look is taken at the classification associated with Jet tagging in hadron collisions. In this review, various state-of-the-art (SOTA) techniques in ML and DL are examined, with a focus on their implications for HEP demands. More precisely, this discussion addresses various applications in extensive detail, such as Jet tagging, Jet tracking, and particle classification. The review concludes with an analysis of the current state of HEP using DL methodologies. It highlights the challenges and potential areas for future research, which are illustrated for each application.

  • Perspective
    Natural Host–Environmental Media–Human: A New Potential Pathway of COVID-19 Outbreak
    Miao Li , Yunfeng Yang , Yun Lu , Dayi Zhang , Yi Liu , Xiaofeng Cui , Lei Yang , Ruiping Liu , Jianguo Liu , Guanghe Li , Jiuhui Qu

    Nowadays, there has been a growing trend in the field of high-energy physics (HEP), in both its experimental and phenomenological studies, to incorporate machine learning (ML) and its specialized branch, deep learning (DL). This review paper provides a thorough illustration of these applications using different ML and DL approaches. The first part of the paper examines the basics of various particle physics types and establishes guidelines for assessing particle physics alongside the available learning models. Next, a detailed classification is provided for representing Jets that are reconstructed in high-energy collisions, mainly in proton-proton collisions at well-defined beam energies. This section covers various datasets, preprocessing techniques, and feature extraction and selection methods. The presented techniques can be applied to future hadron−hadron colliders (HHC), such as the high-luminosity LHC (HL-LHC) and the future circular collider−hadron−hadron (FCC-hh). The authors then explore several AI techniques analyses designed specifically for both image and point-cloud (PC) data in HEP. Additionally, a closer look is taken at the classification associated with Jet tagging in hadron collisions. In this review, various state-of-the-art (SOTA) techniques in ML and DL are examined, with a focus on their implications for HEP demands. More precisely, this discussion addresses various applications in extensive detail, such as Jet tagging, Jet tracking, and particle classification. The review concludes with an analysis of the current state of HEP using DL methodologies. It highlights the challenges and potential areas for future research, which are illustrated for each application.

  • Perspective
    The Scientific Foundation of Chinese Herbal Medicine against COVID-19
    Elaine Lai-Han Leung , Hu-Dan Pan , Yu-Feng Huang , Xing-Xing Fan , Wan-Ying Wang , Fang He , Jun Cai , Hua Zhou , Liang Liu

    Nowadays, there has been a growing trend in the field of high-energy physics (HEP), in both its experimental and phenomenological studies, to incorporate machine learning (ML) and its specialized branch, deep learning (DL). This review paper provides a thorough illustration of these applications using different ML and DL approaches. The first part of the paper examines the basics of various particle physics types and establishes guidelines for assessing particle physics alongside the available learning models. Next, a detailed classification is provided for representing Jets that are reconstructed in high-energy collisions, mainly in proton-proton collisions at well-defined beam energies. This section covers various datasets, preprocessing techniques, and feature extraction and selection methods. The presented techniques can be applied to future hadron−hadron colliders (HHC), such as the high-luminosity LHC (HL-LHC) and the future circular collider−hadron−hadron (FCC-hh). The authors then explore several AI techniques analyses designed specifically for both image and point-cloud (PC) data in HEP. Additionally, a closer look is taken at the classification associated with Jet tagging in hadron collisions. In this review, various state-of-the-art (SOTA) techniques in ML and DL are examined, with a focus on their implications for HEP demands. More precisely, this discussion addresses various applications in extensive detail, such as Jet tagging, Jet tracking, and particle classification. The review concludes with an analysis of the current state of HEP using DL methodologies. It highlights the challenges and potential areas for future research, which are illustrated for each application.

  • Article
    Buying Time for an Effective Epidemic Response: The Impact of a Public Holiday for Outbreak Control on COVID-19 Epidemic Spread
    Simiao Chen , Qiushi Chen , Weizhong Yang , Lan Xue , Yuanli Liu , Juntao Yang , Chen Wang , Till Bärnighausen

    Nowadays, there has been a growing trend in the field of high-energy physics (HEP), in both its experimental and phenomenological studies, to incorporate machine learning (ML) and its specialized branch, deep learning (DL). This review paper provides a thorough illustration of these applications using different ML and DL approaches. The first part of the paper examines the basics of various particle physics types and establishes guidelines for assessing particle physics alongside the available learning models. Next, a detailed classification is provided for representing Jets that are reconstructed in high-energy collisions, mainly in proton-proton collisions at well-defined beam energies. This section covers various datasets, preprocessing techniques, and feature extraction and selection methods. The presented techniques can be applied to future hadron−hadron colliders (HHC), such as the high-luminosity LHC (HL-LHC) and the future circular collider−hadron−hadron (FCC-hh). The authors then explore several AI techniques analyses designed specifically for both image and point-cloud (PC) data in HEP. Additionally, a closer look is taken at the classification associated with Jet tagging in hadron collisions. In this review, various state-of-the-art (SOTA) techniques in ML and DL are examined, with a focus on their implications for HEP demands. More precisely, this discussion addresses various applications in extensive detail, such as Jet tagging, Jet tracking, and particle classification. The review concludes with an analysis of the current state of HEP using DL methodologies. It highlights the challenges and potential areas for future research, which are illustrated for each application.

  • Article
    Can Masks Be Reused After Hot Water Decontamination During the COVID-19 Pandemic?
    Dan Wang , Bao-Chang Sun , Jie-Xin Wang , Yun-Yun Zhou , Zhuo-Wei Chen , Yan Fang , Wei-Hua Yue , Si-Min Liu , Ke-Yang Liu , Xiao-Fei Zeng , Guang-Wen Chu , Jian-Feng Chen

    Nowadays, there has been a growing trend in the field of high-energy physics (HEP), in both its experimental and phenomenological studies, to incorporate machine learning (ML) and its specialized branch, deep learning (DL). This review paper provides a thorough illustration of these applications using different ML and DL approaches. The first part of the paper examines the basics of various particle physics types and establishes guidelines for assessing particle physics alongside the available learning models. Next, a detailed classification is provided for representing Jets that are reconstructed in high-energy collisions, mainly in proton-proton collisions at well-defined beam energies. This section covers various datasets, preprocessing techniques, and feature extraction and selection methods. The presented techniques can be applied to future hadron−hadron colliders (HHC), such as the high-luminosity LHC (HL-LHC) and the future circular collider−hadron−hadron (FCC-hh). The authors then explore several AI techniques analyses designed specifically for both image and point-cloud (PC) data in HEP. Additionally, a closer look is taken at the classification associated with Jet tagging in hadron collisions. In this review, various state-of-the-art (SOTA) techniques in ML and DL are examined, with a focus on their implications for HEP demands. More precisely, this discussion addresses various applications in extensive detail, such as Jet tagging, Jet tracking, and particle classification. The review concludes with an analysis of the current state of HEP using DL methodologies. It highlights the challenges and potential areas for future research, which are illustrated for each application.

  • Article
    A Deep Learning System to Screen Novel Coronavirus Disease 2019 Pneumonia
    Xiaowei Xu , Xiangao Jiang , Chunlian Ma , Peng Du , Xukun Li , Shuangzhi Lv , Liang Yu , Qin Ni , Yanfei Chen , Junwei Su , Guanjing Lang , Yongtao Li , Hong Zhao , Jun Liu , Kaijin Xu , Lingxiang Ruan , Jifang Sheng , Yunqing Qiu , Wei Wu , Tingbo Liang , Lanjuan Li

    Nowadays, there has been a growing trend in the field of high-energy physics (HEP), in both its experimental and phenomenological studies, to incorporate machine learning (ML) and its specialized branch, deep learning (DL). This review paper provides a thorough illustration of these applications using different ML and DL approaches. The first part of the paper examines the basics of various particle physics types and establishes guidelines for assessing particle physics alongside the available learning models. Next, a detailed classification is provided for representing Jets that are reconstructed in high-energy collisions, mainly in proton-proton collisions at well-defined beam energies. This section covers various datasets, preprocessing techniques, and feature extraction and selection methods. The presented techniques can be applied to future hadron−hadron colliders (HHC), such as the high-luminosity LHC (HL-LHC) and the future circular collider−hadron−hadron (FCC-hh). The authors then explore several AI techniques analyses designed specifically for both image and point-cloud (PC) data in HEP. Additionally, a closer look is taken at the classification associated with Jet tagging in hadron collisions. In this review, various state-of-the-art (SOTA) techniques in ML and DL are examined, with a focus on their implications for HEP demands. More precisely, this discussion addresses various applications in extensive detail, such as Jet tagging, Jet tracking, and particle classification. The review concludes with an analysis of the current state of HEP using DL methodologies. It highlights the challenges and potential areas for future research, which are illustrated for each application.

  • Article
    A High-Throughput, Multi-Index Isothermal Amplification Platform for Rapid Detection of 19 Types of Common Respiratory Viruses Including SARS-CoV-2
    Wanli Xing , Yingying Liu , Huili Wang , Shanglin Li , Yongping Lin , Lei Chen , Yan Zhao , Shuang Chao , Xiaolan Huang , Shaolin Ge , Tao Deng , Tian Zhao , Baolian Li , Hanbo Wang , Lei Wang , Yunpeng Song , Ronghua Jin , Jianxing He , Xiuying Zhao , Peng Liu , Weimin Li , Jing Cheng

    Nowadays, there has been a growing trend in the field of high-energy physics (HEP), in both its experimental and phenomenological studies, to incorporate machine learning (ML) and its specialized branch, deep learning (DL). This review paper provides a thorough illustration of these applications using different ML and DL approaches. The first part of the paper examines the basics of various particle physics types and establishes guidelines for assessing particle physics alongside the available learning models. Next, a detailed classification is provided for representing Jets that are reconstructed in high-energy collisions, mainly in proton-proton collisions at well-defined beam energies. This section covers various datasets, preprocessing techniques, and feature extraction and selection methods. The presented techniques can be applied to future hadron−hadron colliders (HHC), such as the high-luminosity LHC (HL-LHC) and the future circular collider−hadron−hadron (FCC-hh). The authors then explore several AI techniques analyses designed specifically for both image and point-cloud (PC) data in HEP. Additionally, a closer look is taken at the classification associated with Jet tagging in hadron collisions. In this review, various state-of-the-art (SOTA) techniques in ML and DL are examined, with a focus on their implications for HEP demands. More precisely, this discussion addresses various applications in extensive detail, such as Jet tagging, Jet tracking, and particle classification. The review concludes with an analysis of the current state of HEP using DL methodologies. It highlights the challenges and potential areas for future research, which are illustrated for each application.

  • Article
    Implementation of Clinical Diagnostic Criteria and Universal Symptom Survey Contributed to Lower Magnitude and Faster Resolution of the COVID-19 Epidemic in Wuhan
    Yongyue Wei , Liangmin Wei , Yue Jiang , Sipeng Shen , Yang Zhao , Yuantao Hao , Zhicheng Du , Jinling Tang , Zhijie Zhang , Qingwu Jiang , Liming Li , Feng Chen , Hongbing Shen

    Nowadays, there has been a growing trend in the field of high-energy physics (HEP), in both its experimental and phenomenological studies, to incorporate machine learning (ML) and its specialized branch, deep learning (DL). This review paper provides a thorough illustration of these applications using different ML and DL approaches. The first part of the paper examines the basics of various particle physics types and establishes guidelines for assessing particle physics alongside the available learning models. Next, a detailed classification is provided for representing Jets that are reconstructed in high-energy collisions, mainly in proton-proton collisions at well-defined beam energies. This section covers various datasets, preprocessing techniques, and feature extraction and selection methods. The presented techniques can be applied to future hadron−hadron colliders (HHC), such as the high-luminosity LHC (HL-LHC) and the future circular collider−hadron−hadron (FCC-hh). The authors then explore several AI techniques analyses designed specifically for both image and point-cloud (PC) data in HEP. Additionally, a closer look is taken at the classification associated with Jet tagging in hadron collisions. In this review, various state-of-the-art (SOTA) techniques in ML and DL are examined, with a focus on their implications for HEP demands. More precisely, this discussion addresses various applications in extensive detail, such as Jet tagging, Jet tracking, and particle classification. The review concludes with an analysis of the current state of HEP using DL methodologies. It highlights the challenges and potential areas for future research, which are illustrated for each application.

  • Article
    Core Outcome Set for Clinical Trials on Coronavirus Disease 2019 (COS-COVID)
    Xinyao Jin , Bo Pang , Junhua Zhang , Qingquan Liu , Zhongqi Yang , Jihong Feng , Xuezheng Liu , Lei Zhang , Baohe Wang , Yuhong Huang , Alice Josephine Fauci , Yuling Ma , Myeong Soo Lee , Wei’an Yuan , Yanming Xie , Jianyuan Tang , Rui Gao , Liang Du , Shuo Zhang , Hanmei Qi , Yu Sun , Wenke Zheng , Fengwen Yang , Huizi Chua , Keyi Wang , Yi Ou , Ming Huang , Yan Zhu , Jiajie Yu , Jinhui Tian , Min Zhao , Jingqing Hu , Chen Yao , Youping Li , Boli Zhang

    Nowadays, there has been a growing trend in the field of high-energy physics (HEP), in both its experimental and phenomenological studies, to incorporate machine learning (ML) and its specialized branch, deep learning (DL). This review paper provides a thorough illustration of these applications using different ML and DL approaches. The first part of the paper examines the basics of various particle physics types and establishes guidelines for assessing particle physics alongside the available learning models. Next, a detailed classification is provided for representing Jets that are reconstructed in high-energy collisions, mainly in proton-proton collisions at well-defined beam energies. This section covers various datasets, preprocessing techniques, and feature extraction and selection methods. The presented techniques can be applied to future hadron−hadron colliders (HHC), such as the high-luminosity LHC (HL-LHC) and the future circular collider−hadron−hadron (FCC-hh). The authors then explore several AI techniques analyses designed specifically for both image and point-cloud (PC) data in HEP. Additionally, a closer look is taken at the classification associated with Jet tagging in hadron collisions. In this review, various state-of-the-art (SOTA) techniques in ML and DL are examined, with a focus on their implications for HEP demands. More precisely, this discussion addresses various applications in extensive detail, such as Jet tagging, Jet tracking, and particle classification. The review concludes with an analysis of the current state of HEP using DL methodologies. It highlights the challenges and potential areas for future research, which are illustrated for each application.

  • Article
    Clinical Study of Mesenchymal Stem Cell Treatment for Acute Respiratory Distress Syndrome Induced by Epidemic Influenza A (H7N9) Infection: A Hint for COVID-19 Treatment
    Jiajia Chen , Chenxia Hu , Lijun Chen , Lingling Tang , Yixin Zhu , Xiaowei Xu , Lu Chen , Hainv Gao , Xiaoqing Lu , Liang Yu , Xiahong Dai , Charlie Xiang , Lanjuan Li

    Nowadays, there has been a growing trend in the field of high-energy physics (HEP), in both its experimental and phenomenological studies, to incorporate machine learning (ML) and its specialized branch, deep learning (DL). This review paper provides a thorough illustration of these applications using different ML and DL approaches. The first part of the paper examines the basics of various particle physics types and establishes guidelines for assessing particle physics alongside the available learning models. Next, a detailed classification is provided for representing Jets that are reconstructed in high-energy collisions, mainly in proton-proton collisions at well-defined beam energies. This section covers various datasets, preprocessing techniques, and feature extraction and selection methods. The presented techniques can be applied to future hadron−hadron colliders (HHC), such as the high-luminosity LHC (HL-LHC) and the future circular collider−hadron−hadron (FCC-hh). The authors then explore several AI techniques analyses designed specifically for both image and point-cloud (PC) data in HEP. Additionally, a closer look is taken at the classification associated with Jet tagging in hadron collisions. In this review, various state-of-the-art (SOTA) techniques in ML and DL are examined, with a focus on their implications for HEP demands. More precisely, this discussion addresses various applications in extensive detail, such as Jet tagging, Jet tracking, and particle classification. The review concludes with an analysis of the current state of HEP using DL methodologies. It highlights the challenges and potential areas for future research, which are illustrated for each application.

  • Article
    SARS-CoV-2 Entry Factors: ACE2 and TMPRSS2 Are Expressed in Peri-Implantation Embryos and the Maternal–Fetal Interface
    Wei Chen , Peng Yuan , Ming Yang , Zhiqiang Yan , Siming Kong , Jie Yan , Xixi Liu , Yidong Chen , Jie Qiao , Liying Yan

    Nowadays, there has been a growing trend in the field of high-energy physics (HEP), in both its experimental and phenomenological studies, to incorporate machine learning (ML) and its specialized branch, deep learning (DL). This review paper provides a thorough illustration of these applications using different ML and DL approaches. The first part of the paper examines the basics of various particle physics types and establishes guidelines for assessing particle physics alongside the available learning models. Next, a detailed classification is provided for representing Jets that are reconstructed in high-energy collisions, mainly in proton-proton collisions at well-defined beam energies. This section covers various datasets, preprocessing techniques, and feature extraction and selection methods. The presented techniques can be applied to future hadron−hadron colliders (HHC), such as the high-luminosity LHC (HL-LHC) and the future circular collider−hadron−hadron (FCC-hh). The authors then explore several AI techniques analyses designed specifically for both image and point-cloud (PC) data in HEP. Additionally, a closer look is taken at the classification associated with Jet tagging in hadron collisions. In this review, various state-of-the-art (SOTA) techniques in ML and DL are examined, with a focus on their implications for HEP demands. More precisely, this discussion addresses various applications in extensive detail, such as Jet tagging, Jet tracking, and particle classification. The review concludes with an analysis of the current state of HEP using DL methodologies. It highlights the challenges and potential areas for future research, which are illustrated for each application.

  • Article
    Clinical Characteristics and Outcomes of Type 2 Diabetes Patients Infected with SARS-CoV-2: A Retrospective Study
    Yingyu Chen , Jiankun Chen , Xiao Gong , Xianglu Rong , Dewei Ye , Yinghua Jin , Zhongde Zhang , Jiqiang Li , Jiao Guo

    Nowadays, there has been a growing trend in the field of high-energy physics (HEP), in both its experimental and phenomenological studies, to incorporate machine learning (ML) and its specialized branch, deep learning (DL). This review paper provides a thorough illustration of these applications using different ML and DL approaches. The first part of the paper examines the basics of various particle physics types and establishes guidelines for assessing particle physics alongside the available learning models. Next, a detailed classification is provided for representing Jets that are reconstructed in high-energy collisions, mainly in proton-proton collisions at well-defined beam energies. This section covers various datasets, preprocessing techniques, and feature extraction and selection methods. The presented techniques can be applied to future hadron−hadron colliders (HHC), such as the high-luminosity LHC (HL-LHC) and the future circular collider−hadron−hadron (FCC-hh). The authors then explore several AI techniques analyses designed specifically for both image and point-cloud (PC) data in HEP. Additionally, a closer look is taken at the classification associated with Jet tagging in hadron collisions. In this review, various state-of-the-art (SOTA) techniques in ML and DL are examined, with a focus on their implications for HEP demands. More precisely, this discussion addresses various applications in extensive detail, such as Jet tagging, Jet tracking, and particle classification. The review concludes with an analysis of the current state of HEP using DL methodologies. It highlights the challenges and potential areas for future research, which are illustrated for each application.

  • Article
    Clinical Significance of the Correlation between Changes in the Major Intestinal Bacteria Species and COVID-19 Severity
    Lingling Tang , Silan Gu , Yiwen Gong , Bo Li , Haifeng Lu , Qiang Li , Ruhong Zhang , Xiang Gao , Zhengjie Wu , Jiaying Zhang , Yuanyuan Zhang , Lanjuan Li

    Nowadays, there has been a growing trend in the field of high-energy physics (HEP), in both its experimental and phenomenological studies, to incorporate machine learning (ML) and its specialized branch, deep learning (DL). This review paper provides a thorough illustration of these applications using different ML and DL approaches. The first part of the paper examines the basics of various particle physics types and establishes guidelines for assessing particle physics alongside the available learning models. Next, a detailed classification is provided for representing Jets that are reconstructed in high-energy collisions, mainly in proton-proton collisions at well-defined beam energies. This section covers various datasets, preprocessing techniques, and feature extraction and selection methods. The presented techniques can be applied to future hadron−hadron colliders (HHC), such as the high-luminosity LHC (HL-LHC) and the future circular collider−hadron−hadron (FCC-hh). The authors then explore several AI techniques analyses designed specifically for both image and point-cloud (PC) data in HEP. Additionally, a closer look is taken at the classification associated with Jet tagging in hadron collisions. In this review, various state-of-the-art (SOTA) techniques in ML and DL are examined, with a focus on their implications for HEP demands. More precisely, this discussion addresses various applications in extensive detail, such as Jet tagging, Jet tracking, and particle classification. The review concludes with an analysis of the current state of HEP using DL methodologies. It highlights the challenges and potential areas for future research, which are illustrated for each application.

  • Article
    Efficacy and Safety of Triazavirin Therapy for Coronavirus Disease 2019: A Pilot Randomized Controlled Trial
    Xiaoke Wu , Kaijiang Yu , Yongchen Wang , Wanhai Xu , Hongli Ma , Yan Hou , Yue Li , Benzhi Cai , Liying Zhu , Min Zhang , Xiaoli Hu , Jingshu Gao , Yu Wang , Huichao Qin , Wenjie Wang , Mingyan Zhao , Xia Wu , Yong Zhang , Lu Li , Kang Li , Zhimin Du , Ben Willem J. Mol , Baofeng Yang

    Nowadays, there has been a growing trend in the field of high-energy physics (HEP), in both its experimental and phenomenological studies, to incorporate machine learning (ML) and its specialized branch, deep learning (DL). This review paper provides a thorough illustration of these applications using different ML and DL approaches. The first part of the paper examines the basics of various particle physics types and establishes guidelines for assessing particle physics alongside the available learning models. Next, a detailed classification is provided for representing Jets that are reconstructed in high-energy collisions, mainly in proton-proton collisions at well-defined beam energies. This section covers various datasets, preprocessing techniques, and feature extraction and selection methods. The presented techniques can be applied to future hadron−hadron colliders (HHC), such as the high-luminosity LHC (HL-LHC) and the future circular collider−hadron−hadron (FCC-hh). The authors then explore several AI techniques analyses designed specifically for both image and point-cloud (PC) data in HEP. Additionally, a closer look is taken at the classification associated with Jet tagging in hadron collisions. In this review, various state-of-the-art (SOTA) techniques in ML and DL are examined, with a focus on their implications for HEP demands. More precisely, this discussion addresses various applications in extensive detail, such as Jet tagging, Jet tracking, and particle classification. The review concludes with an analysis of the current state of HEP using DL methodologies. It highlights the challenges and potential areas for future research, which are illustrated for each application.

  • Article
    Experimental Treatment with Favipiravir for COVID-19: An Open-Label Control Study
    Qingxian Cai , Minghui Yang , Dongjing Liu , Jun Chen , Dan Shu , Junxia Xia , Xuejiao Liao , Yuanbo Gu , Qiue Cai , Yang Yang , Chenguang Shen , Xiaohe Li , Ling Peng , Deliang Huang , Jing Zhang , Shurong Zhang , Fuxiang Wang , Jiaye Liu , Li Chen , Shuyan Chen , Zhaoqin Wang , Zheng Zhang , Ruiyuan Cao , Wu Zhong , Yingxia Liu , Lei Liu Cai

    Nowadays, there has been a growing trend in the field of high-energy physics (HEP), in both its experimental and phenomenological studies, to incorporate machine learning (ML) and its specialized branch, deep learning (DL). This review paper provides a thorough illustration of these applications using different ML and DL approaches. The first part of the paper examines the basics of various particle physics types and establishes guidelines for assessing particle physics alongside the available learning models. Next, a detailed classification is provided for representing Jets that are reconstructed in high-energy collisions, mainly in proton-proton collisions at well-defined beam energies. This section covers various datasets, preprocessing techniques, and feature extraction and selection methods. The presented techniques can be applied to future hadron−hadron colliders (HHC), such as the high-luminosity LHC (HL-LHC) and the future circular collider−hadron−hadron (FCC-hh). The authors then explore several AI techniques analyses designed specifically for both image and point-cloud (PC) data in HEP. Additionally, a closer look is taken at the classification associated with Jet tagging in hadron collisions. In this review, various state-of-the-art (SOTA) techniques in ML and DL are examined, with a focus on their implications for HEP demands. More precisely, this discussion addresses various applications in extensive detail, such as Jet tagging, Jet tracking, and particle classification. The review concludes with an analysis of the current state of HEP using DL methodologies. It highlights the challenges and potential areas for future research, which are illustrated for each application.

  • Protocol
    The Efficacy and Safety of Triazavirin for COVID-19: A Trial Protocol
    Xiaoke Wu , Kaijiang Yu , Yongchen Wang , Wanhai Xu , Hongli Ma , Yan Hou , Yue Li , Benzhi Cai , Liying Zhu , Min Zhang , Xiaoli Hu , Jingshu Gao , Yu Wang , Huichao Qin , Mingyan Zhao , Yong Zhang , Kang Li , Zhimin Du , Baofeng Yang

    Nowadays, there has been a growing trend in the field of high-energy physics (HEP), in both its experimental and phenomenological studies, to incorporate machine learning (ML) and its specialized branch, deep learning (DL). This review paper provides a thorough illustration of these applications using different ML and DL approaches. The first part of the paper examines the basics of various particle physics types and establishes guidelines for assessing particle physics alongside the available learning models. Next, a detailed classification is provided for representing Jets that are reconstructed in high-energy collisions, mainly in proton-proton collisions at well-defined beam energies. This section covers various datasets, preprocessing techniques, and feature extraction and selection methods. The presented techniques can be applied to future hadron−hadron colliders (HHC), such as the high-luminosity LHC (HL-LHC) and the future circular collider−hadron−hadron (FCC-hh). The authors then explore several AI techniques analyses designed specifically for both image and point-cloud (PC) data in HEP. Additionally, a closer look is taken at the classification associated with Jet tagging in hadron collisions. In this review, various state-of-the-art (SOTA) techniques in ML and DL are examined, with a focus on their implications for HEP demands. More precisely, this discussion addresses various applications in extensive detail, such as Jet tagging, Jet tracking, and particle classification. The review concludes with an analysis of the current state of HEP using DL methodologies. It highlights the challenges and potential areas for future research, which are illustrated for each application.