Search | Engineering

订阅投稿

首页工程期刊工程焦点工程成就工程前沿关于我们 English

资源类型

期刊论文 909

会议视频 44

会议信息 9

年份

2024 1

2023 104

2022 145

2021 109

2020 87

2019 63

2018 53

2017 48

2016 35

2015 40

2014 32

2013 32

2012 28

2011 19

2010 24

2009 29

2008 22

2007 31

2006 7

2005 7

展开︾

关键词

3D打印 13

增材制造 11

院士大会 9

组织工程 8

医学 5

经济 5

营养健康 5

4D打印 4

工程管理 3

干细胞 3

生物材料 3

空间可展开结构 3

第四届 3

肠道菌群 3

调节性T细胞 3

2019 2

2020 2

3D生物打印 2

COVID-19 2

展开︾

检索范围：

排序：展示方式：

3D 打印细胞容器样支架在多细胞组织工程中的应用研究 Article

王晓亚, 张猛, 马景阁, 徐梦驰, 常江, Michael Gelinsky, 吴成铁

《工程（英文）》 2020年第6卷第11期页码 1276-1284 doi: 10.1016/j.eng.2020.08.001

摘要：本研究利用3D打印技术，成功制得了一种含β-磷酸三钙/羟基磷灰石（β-TCP/HA）的细胞容器样支架，该支架设计了四种不同形状的微孔结构：三角形、正方形、平行四边形和长方形微孔结构。本研究构建了一种由人骨髓间质干细胞（HBMSC）、人脐静脉内皮细胞（HUVEC）、人脐静脉平滑肌细胞（HUVSMC）、人真皮成纤维细胞（HDF）组成的3D共培养模型，用以研究这些细胞在促进骨生成和血管生成过程中细胞的个体效应与协同效应结果表明，相较于在3D细胞容器中仅培养一种细胞，共培养三种或四种细胞展现出了更高的细胞增殖率。HBMSC与HUVEC的细胞间相互作用的研究表明，含有四种独立空间结构的3D细胞容器可以通过放大共培养细胞的旁分泌效应促进细胞的骨生成和血管生成能力。此外，在3D细胞容器中建立多细胞非接触体系，特别是含有三种或四种细胞的共培养体系，相对于单细胞培养模式与两种细胞共培养模式来说，在促进细胞成骨分化和成血管分化方面展现出明显的优势。

关键词： 3D细胞容器非接触式多细胞共培养相互作用血管生成骨生成

HTML PDF 收藏

三维仿生支架平台的刚度和层尺寸对癌细胞分离的影响 Article

张维冠, 刘子玉, 彭慧芝

《工程（英文）》 2021年第7卷第10期页码 1426-1435 doi: 10.1016/j.eng.2020.09.010

摘要：除了生化方法，工程化平台是根据癌细胞响应周围微环境物理变化的独特特性将癌细胞与正常细胞分离的有效选择。本研究根据精确控制的设计参数（包括刚度、层数和结构布局），开发了三维（3D）仿生支架平台，用于分离鼻咽癌（NPC43）细胞与永生化鼻咽上皮（NP460）细胞。支架平台上NPC43细胞和NP460细胞的迁移特征表明，NPC43细胞可以挤进10 µm宽、15 µm深的沟槽，而NP460细胞不能。迁移行为的不同主要是由细胞与周围微环境的交互作用不同所导致。NPC43细胞具有丝状伪足样突触，而NP460细胞呈片状形态。使用这些3D仿生平台进行研究发现，在较硬的双层支架平台[顶层为40/10 μm沟脊/沟槽（R/T）栅格，底层为20/10 μm R/T网格]上，NPC43细胞与NP460细胞的分离效率可达89%

关键词：细胞分离细胞迁移鼻咽癌（NPC） 3D支架平台

HTML PDF 收藏

关于3D打印技术在医学模具以及再生组织和器官方面的应用综述

Kan Wang, Chia-Che Ho, Chuck Zhang, Ben Wang

《工程（英文）》 2017年第3卷第5期页码 653-662 doi: 10.1016/J.ENG.2017.05.013

摘要：随着三维（3D）打印和3D 生物打印技术的快速发展，许多研究人员已经开始使用增材制造技术来生产具有多种功能的医学模具。本文综述了3D 打印和3D 生物打印技术在制作功能性医学模具和生物结构方面的应用。特别讨论了3D 打印功能性医学模具（即组织模拟医学模具、放射性医学模具和生理医学模具）及被用于再生组织和器官的3D 生物打印模具的制备（即混合模式支架材料、可转换支架和集成传感器）工艺、发展现状以及未来发展趋势

关键词： 3D打印 3D生物打印医学模具再生组织/器官支架

HTML PDF 收藏

Animage-based approach to the reconstruction of ancient architectures by extracting and arranging 3D

Divya Udayan J,HyungSeok KIM,Jee-In KIM

《信息与电子工程前沿（英文）》 2015年第16卷第1期页码 12-27 doi: 10.1631/FITEE.1400141

摘要： The objective of this research is the rapid reconstruction of ancient buildings of historical importance using a single image. The key idea of our approach is to reduce the infinite solutions that might otherwise arise when recovering a 3D geometry from 2D photographs. The main outcome of our research shows that the proposed methodology can be used to reconstruct ancient monuments for use as proxies for digital effects in applications such as tourism, games, and entertainment, which do not require very accurate modeling. In this article, we consider the reconstruction of ancient Mughal architecture including the Taj Mahal. We propose a modeling pipeline that makes an easy reconstruction possible using a single photograph taken from a single view, without the need to create complex point clouds from multiple images or the use of laser scanners. First, an initial model is automatically reconstructed using locally fitted planar primitives along with their boundary polygons and the adjacency relation among parts of the polygons. This approach is faster and more accurate than creating a model from scratch because the initial reconstruction phase provides a set of structural information together with the adjacency relation, which makes it possible to estimate the approximate depth of the entire structural monument. Next, we use manual extrapolation and editing techniques with modeling software to assemble and adjust different 3D components of the model. Thus, this research opens up the opportunity for the present generation to experience remote sites of architectural and cultural importance through virtual worlds and real-time mobile applications. Variations of a recreated 3D monument to represent an amalgam of various cultures are targeted for future work.

关键词： Digital reconstruction 3D virtual world 3D spatial components Vision and scene understanding

HTML PDF 收藏

增材制造（3D打印）发展趋势 Perspective

卢秉恒, 李涤尘, 田小永

《工程（英文）》 2015年第1卷第1期页码 85-89 doi: 10.15302/J-ENG-2015012

摘要：

增材制造又称为3D打印，在过去30年间取得了快速发展并展示出前所未有的发展潜力。同时，这项发展潜力巨大的技术对传统工业也产生了不可估量的影响。3D打印技术将会推动生产模式的变革，通过实现5个“任意”的工艺发展，将会为制造行业带来一个以定制化制造为特征的新时代。3D打印的技术进步及其与传统制造工艺的融合，将推动制造业在材料研发、产品设计、生产工艺等方面进一步创新发展。最终，3D打印技术将与等材制造、减材制造形成三足鼎立局面，共同分享整个社会的制造业价值。

关键词：增材制造 3D打印制造模式定制化制造创新设计

HTML PDF 收藏

Construction of digital 3D magic-cube organization structure for innovation-driven manufacturing

《工程管理前沿（英文）》页码 373-390 doi: 10.1007/s42524-022-0237-x

摘要： Owing to the heterogeneity between functional units and resource scarcity, manufacturing firms have been struggling with intra-organizational coordination for productivity and innovation. Traditional organizational structures, such as linear-functional and matrix, may cause responsibility division and independent goals (Shahani, 2020), and are more difficult to be adopted by large-sized innovative manufacturing firms for quantity production. This is based on a review of several new forms of organization (i.e., network organization, multiteam system, and platform organization) compared with the traditional forms of organization (i.e., linear, matrix, and business unit organization, among others). This study proposes a three-dimensional (3D) magic-cube organizational structure, considering the product dimensions, business, and administration. Moreover, the characteristics, propositions of system operation, system dynamic model, and working model of the 3D magic-cube organization are described. Finally, the 3D model is applied in a Chinese manufacturing firm to test its effectiveness. By redesigning the post and pay system, the pilot organization establishes a project-driven and cross-functional coordination mechanism, positively affecting the firm’s financial profit, output value, labor productivity, and income of per capita. The proposed 3D model can be adopted by large- or medium-sized manufacturing firms for product development and innovation. The implications of both practice and theory are also discussed in this study.

关键词： innovation manufacturing 3D magic-cube organization structure coordination

HTML PDF 收藏

3D打印技术在多个领域取得进展

Chris Palmer

《工程（英文）》 2020年第6卷第6期页码 590-592 doi: 10.1016/j.eng.2020.04.005

HTML PDF 收藏

Characterization of 3D microstructure, thermal conductivity, and heat flow of cement-based foam using

《结构与土木工程前沿（英文）》 2021年第15卷第3期页码 643-651 doi: 10.1007/s11709-021-0709-9

摘要： This study presents the results of the 3D microstructure, thermal conductivity, and heat flow in cement-based foams and examines their changes with a range of densities. Images were captured using X-ray micro computed tomography (micro-CT) imaging technique on cement-based foam samples prepared with densities of 400, 600, and 800 kg/m³. These images were later simulated and quantified using 3D data visualization and analysis software. Based on the analysis, the pore volume of 11000 µm³ was determined across the three densities, leading to optimal results. However, distinct pore diameters of 15 µm for 800 kg/m³, and 20 µm for 600 and 400 kg/m³ were found to be optimum. Most of the pores were spherical, with only 10% appearing elongated or fractured. In addition, a difference of 15% was observed between the 2D and 3D porosity results. Moreover, a difference of 5% was noticed between the experimentally measured thermal conductivity and the numerically predicted value and this variation was constant across the three cast densities. The 3D model showed that heat flows through the cement paste solids and with an increase in porosity this flow reduces.

关键词： 3D pore volume distribution X-ray tomography 3D shape factor heat flow

HTML PDF 收藏

支架与组织的设计及3D打印 Review

安佳, Joanne Ee Mei Teoh, Ratima Suntornnond, Chee Kai Chua

《工程（英文）》 2015年第1卷第2期页码 261-268 doi: 10.15302/J-ENG-2015061

摘要：

目前，组织工程学中应用3D打印工艺的情况越来越多。本文介绍3D打印技术在组织工程学应用领域的最前沿研究，尤其侧重于计算机辅助支架设计系统的开发、功能梯度支架的直接3D打印、选择性激光烧结 (SLS) 和熔融沉积成型 (FDM) 工艺建模、利用微观和宏观特征进行支架间接增材制造、生物反应器的开发，以及3D/4D生物打印。本文还讨论3D打印的技术限制，进而突出新3D打印方法在组织工程学领域得到进一步改善的可能性。

关键词：快速原型制造 3D打印增材制造组织工程生物打印

HTML PDF 收藏

募集抗原特异性T细胞的3D打印支架促进血管化 Article

李翠笛, 马振江, 李文韬, 颉天阳, 钟丽萍, 陈宏方, 王文豪, 王金武, 崔文国, 赵永祥

《工程（英文）》 2022年第17卷第10期页码 183-195 doi: 10.1016/j.eng.2021.05.018

摘要：

3D打印支架植入后激起的免疫反应是组织修复效果的主要决定性因素。因此，巧妙调控免疫反应的支架材料具有高效修复组织的潜能。本研究受抗原特异性免疫反应对血管新生促进作用的启发，通过动态共价键将介孔二氧化硅微棒（MSR）/聚乙烯亚胺（PEI）/卵清蛋白（OVA）自组装疫苗与3D打印自固化磷酸钙骨水泥（CPC）基支架结合，构建了一种具有调控局部体液免疫反应功能的组织修复支架通过局部释放OVA激活体液免疫反应，支架可有效募集抗原特异性CD4⁺ 2 型辅助性T细胞（Th2 细胞），从而促进支架植入早期的血管新生；在提供充足和丰富的血供环境的同时，MSR微棒中释放的硅离子还能有效加速骨再生在体外实验中，该疫苗负载支架有效募集并激活了树突细胞使树突细胞呈递抗原，还促进了骨髓间充质干细胞（BMSC）成骨分化。在皮下包埋实验中，疫苗负载支架增加了Th2 细胞在脾脏中的比例，局部募集了抗原特异性T细胞并促进了支架内的血管新生。此外，原位颅骨缺损修复模型结果表明，负载疫苗的支架可促进血管化骨组织再生。

关键词： 3D打印免疫微环境调控血管新生骨再生

HTML PDF 收藏

Seepage analysis of Upper Gotvand Dam concerning gypsum karstification (2D and 3D approaches)

Jamshid SADREKARIMI, Majid KIYANI, Behnam FAKHRI, Mohammad Javad VAHDATIRAD, Amin BARARI

《结构与土木工程前沿（英文）》 2011年第5卷第1期页码 71-78 doi: 10.1007/s11709-010-0083-5

摘要： Upper Gotvand Dam is constructed on the Karun River at the south west of Iran. In this paper, 2D and 3D models of the dam together with the foundation and abutments were established, and several seepage analyses were carried out. Then, the gypsum veins that are scattered throughout the foundation ground were included in the models, and the seepage pattern, considering the dissolution law of gypsum, was analyzed. It was disclosed that the discharge fluxes obtained from 2D and 3D analyses are not similar, and the discharge flux in 3D model is about four times that of the 2D model. Also, the 3D model locates the phreatic surface somewhat higher than the 2D model. This means that the 2D model estimates lower pore water pressure pattern in comparison with the 3D model. These may be attributed to the fact that with 2D model the lateral components of vectors of seepage velocity are ignored. In the current case, the rate of increase of discharge flux due to dissolution of gypsum veins was obtained to be a third-order function of the aperture width. In spite of the fact that the grout curtain is designed to be about 170 m deep, however, complete dissolve of gypsum will severely increase the discharge flux through the foundation ground.

关键词： Upper Gotvand Dam seepage analysis gypsum veins 3D model discharge flux

HTML PDF 收藏

面向医学应用的3D 打印技术现状综述 Review

严倩,董汉华,苏瑾,韩建华,宋波,魏青松, 史玉升

《工程（英文）》 2018年第4卷第5期页码 729-742 doi: 10.1016/j.eng.2018.07.021

摘要： 3D 打印技术具有解决目前这些问题的潜力，可用于快速制造个性化组织工程支架、细胞原位修复组织缺陷，甚至直接打印组织和器官。打印的植入体和器官不仅与患者的受损组织完美匹配，而且能够调控材料微结构和细胞排列，促进细胞生长和分化。因此，这类植入体有望实现组织修复，甚至最终解决供体短缺问题。本文总结了3D 打印在医学领域相关研究和最新进展的四个层次，介绍了不同类型的生物医用材料，并讨论了医学应用中3D 打印所需材料和构建体外细胞质基质（ECM）存在的问题和未来的发展方向。

关键词： 3D 打印植入体支架生物医学材料

HTML PDF 收藏

使用2D、3D和4D增材制造材料开发生物植入物 Review

刘果, 何云虎, 刘朋超, 陈舟, 陈绪梁, 万镭, 李莹, 吕坚

《工程（英文）》 2020年第6卷第11期页码 1232-1243 doi: 10.1016/j.eng.2020.04.015

摘要：但是，用于制造生物植入物的3D可打印材料仍然非常有限。本研究对用于生物植入物的2D、3D AM材料进行了概述。此外，在我们团队先前开发的4D打印陶瓷前驱体及陶瓷材料的基础上，受太极思想的启发，本文提出了一种简单而新颖的软硬集成4D增材制造概念，以应用于人体系统中复杂且动态的生物结构。多材料打印技术的发展，使得人们未来可以使用2D、3D、4D AM材料开发生物植入物和软硬集成生物结构。

关键词：生物打印 2D增材制造 3D打印 4D打印生物植入物

HTML PDF 收藏

Direct pyrolysis to convert biomass to versatile 3D carbon nanotubes/mesoporous carbon architecture:

《化学科学与工程前沿（英文）》 2023年第17卷第6期页码 679-690 doi: 10.1007/s11705-022-2266-8

摘要： The massive conversion of resourceful biomass to carbon nanomaterials not only opens a new avenue to effective and economical disposal of biomass, but provides a possibility to produce highly valued functionalized carbon-based electrodes for energy storage and conversion systems. In this work, biomass is applied to a facile and scalable one-step pyrolysis method to prepare three-dimensional (3D) carbon nanotubes/mesoporous carbon architecture, which uses transition metal inorganic salts and melamine as initial precursors. The role of each employed component is investigated, and the electrochemical performance of the attained product is explored. Each component and precise regulation of their dosage is proven to be the key to successful conversion of biomass to the desired carbon nanomaterials. Owing to the unique 3D architecture and integration of individual merits of carbon nanotubes and mesoporous carbon, the as-synthesized carbon nanotubes/mesoporous carbon hybrid exhibits versatile application toward lithium-ion batteries and Zn-air batteries. Apparently, a significant guidance on effective conversion of biomass to functionalized carbon nanomaterials can be shown by this work.

关键词： biomass direct pyrolysis 3D CNTs/MC hybrid lithium-ion batteries Zn-air batteries