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Utility of transbronchial biopsy in the diagnosis of lymphangioleiomyomatosis
null
《医学前沿（英文）》 2012年 第6卷 第4期 页码 395-405 doi: 10.1007/s11684-012-0231-5
Pulmonary lymphangioleiomyomatosis (LAM) is a rare cystic lung disease that targets women during their reproductive years. A confident diagnosis can often be based on clinical grounds, but diagnostic certainty requires pathological analysis. Although surgical lung biopsy is considered the gold standard for obtaining tissue in patients with diffuse lung disease, it is also associated with higher morbidity and mortality than alternative, less invasive techniques. The objective of our study was to examine the utility of transbronchial biopsy in the diagnosis of LAM. We conducted two online surveys of over 1 000 LAM patients registered with the LAM Foundation who were accessible by email. Transbronchial biopsy specimens were subsequently collected and reviewed by an expert pathologist to validate the diagnosis. We found that transbronchial biopsy has a yield of approximately 60% in patients with LAM. We conclude that transbronchial biopsy may be a safe and effective method for establishing the diagnosis of LAM, obviating the need for surgical lung biopsy in more than half of LAM patients.
关键词： lymphangioleiomyomatosis lymphangiomyomatosis multicystic lung disease diffuse cystic lung disease transbronchial biopsy perivascular epithelioid cell tumor (PEComa) HMB-45
Stability and dynamics of rotor system with 45° slant crack on shaft
Yanli LIN, Xiaohui SI, Fulei CHU
《机械工程前沿（英文）》 2011年 第6卷 第2期 页码 203-213 doi: 10.1007/s11465-011-0131-4
Crack on a shaft is one of the common damages in a rotor system. In this paper, transverse vibrations are calculated to compare the influences of transverse crack and slant crack on the rotor system. Results show that the vibration amplitude of the rotor system with a 45° slant crack on the shaft is larger than that with a transverse crack when the two types of crack have the same depth and the rotor system runs in the same condition. Stability and dynamic characteristics of the rotor system with a 45° slant crack on the shaft under torsional excitation are analyzed by considering opening and closing of the crack. It is shown that the instability of the transverse vibration of the rotor system increases with increasing difference between the bending stiffness in two main directions, and the vibration is stable when the two bending stiffness are identical. The spectrum analysis of the steady-state response reveals that the gravity and the eccentricity produce different frequency components, and when the two bending stiffness are identical, the multiple frequency components of the torsional excitation disappear. Further investigation shows that the vibration amplitudes in combined frequencies increase rapidly in transversal, torsional, and axial vibration with increasing slant crack depth. The results are helpful for the understanding the dynamic behavior of a rotor system with a slant crack on a shaft and can be used for the detection of the slant crack on a shaft.
关键词： rotor dynamics slant crack stability torsional excitation open and close
带有时变时滞的分数阶阻尼系统可控性研究 Research Articles
何彬彬1,周华成2,寇春海3
《信息与电子工程前沿（英文）》 2020年 第21卷 第6期 页码 809-962 doi: 10.1631/FITEE.1900736
标题 作者 时间 类型 操作
Stability and dynamics of rotor system with 45° slant crack on shaft
Yanli LIN, Xiaohui SI, Fulei CHU
期刊论文
2019年世界隧道大会暨国际隧协（ITA）第45届年会
2019年05月02日
会议信息
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