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期刊论文 23

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2023 2

2022 3

2021 3

2020 2

2019 1

2017 3

2016 1

2013 1

2011 2

2010 1

2008 1

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关键词

GIS 1

乙酰肝素酶 1

修复 1

制药工业 1

土壤施用 1

地震次生火灾 1

多智能体系统；同步控制；分布式控制 1

多智能体系统；时滞；线性矩阵不等式 1

引力模型；相向行人流；社会力模型；渠化现象；自组织行为 1

心脏代谢 1

抗生素 1

有限时间；协同路径跟踪；多智能体系统；障碍函数 1

模拟系统 1

火灾动态蔓延 1

物质流的基本公式 1

物质流的研究方法 1

物质流的跟踪观察法 1

物质流的非稳度 1

糖尿病性心肌病 1

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Extended model predictive control scheme for smooth path following of autonomous vehicles

《机械工程前沿（英文）》 2022年第17卷第1期页码 4-4 doi: 10.1007/s11465-021-0660-4

摘要： This paper presents an extended model predictive control (MPC) scheme for implementing optimal path following of autonomous vehicles, which has multiple constraints and an integrated model of vehicle and road dynamics. Road curvature and inclination factors are used in the construction of the vehicle dynamic model to describe its lateral and roll dynamics accurately. Sideslip, rollover, and vehicle envelopes are used as multiple constraints in the MPC controller formulation. Then, an extended MPC method solved by differential evolution optimization algorithm is proposed to realize optimal smooth path following based on driving path features. Finally, simulation and real experiments are carried out to evaluate the feasibility and the effectiveness of the extended MPC scheme. Results indicate that the proposed method can obtain the smooth transition to follow the optimal drivable path and satisfy the lateral dynamic stability and environmental constraints, which can improve the path following quality for better ride comfort and road availability of autonomous vehicles.

关键词： autonomous vehicles vehicle dynamic modeling model predictive control path following optimization algorithm

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Right coronary occlusion following transcatheter aortic valve implantation: two case reports

null

《医学前沿（英文）》 2016年第10卷第3期页码 351-355 doi: 10.1007/s11684-016-0465-8

摘要：

This paper discusses two male patients with severe aortic stenosis, whose right coronary arteries (RCA) were completely occluded during transcatheter aortic valve implantation (TAVI), leading to fatal hemodynamic disorder. Occlusions of RCA complicated by TAVI are rare. In addition, emergency cardiopulmonary bypass (CPB) played a critical role in rescuing our second patient. Both patients were admitted for “severe aortic stenosis,” and TAVIs were performed. The first patient’s blood pressure immediately dropped to 70/40 mmHg after the balloon expansion and did not increase much after the administration of aramine or fluid therapy. He did not receive emergency surgery and died after 1.5 h of resuscitation. The second patient’s blood pressure fluctuated greatly for several minutes after the valve implantation, ranging from 170/100 mmHg to 60/40 mmHg. Angiography revealed a total occlusion of RCA. Thoracic surgery with CPB was performed, and the patient survived.

关键词： aortic stenosis transcatheter aortic valve implantation right coronary occlusion cardiac group

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Universal influenza virus vaccines: what can we learn from the human immune response following exposure

null

《医学前沿（英文）》 2017年第11卷第4期页码 471-479 doi: 10.1007/s11684-017-0602-z

摘要：

Several universal influenza virus vaccine candidates based on eliciting antibodies against the hemagglutinin stalk domain are in development. Typically, these vaccines induce responses that target group 1 or group 2 hemagglutinins with little to no cross-group reactivity and protection. Similarly, the majority of human anti-stalk monoclonal antibodies that have been isolated are directed against group 1 or group 2 hemagglutinins with very few that bind to hemagglutinins of both groups. Here we review what is known about the human humoral immune response to vaccination and infection with H7 subtype influenza viruses on a polyclonal and monoclonal level. It seems that unlike vaccination with H5 hemagglutinin, which induces antibody responses mostly restricted to the group 1 stalk domain, H7 exposure induces both group 2 and cross-group antibody responses. A better understanding of this phenomenon and the underlying mechanisms might help to develop future universal influenza virus vaccine candidates.

关键词： universal influenza virus vaccine hemagglutinin stalk H7N9

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ORGANIC CARBON STOCKS IN A SILTY TEXTURED SOIL FOLLOWING REINTEGRATION OF A 20 YEARS OLD × SITE INTO

《农业科学与工程前沿（英文）》 2023年第10卷第2期页码 183-197 doi: 10.15302/J-FASE-2023485

摘要：

● 0.98 Mg·ha⁻¹·yr⁻¹ C_org accumulation under miscanthus over 26 years.

关键词： biobased energy crops C balance humus accumulation

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Appendiceal inflammation affects the length of stay following appendicectomy amongst children: a myth

null

《医学前沿（英文）》 2013年第7卷第2期页码 264-269 doi: 10.1007/s11684-013-0259-1

摘要：

The effect of the severity of appendiceal inflammation on post-operative stay in children following appendicectomy has shown conflicting results. This study was conducted to determine the association between the severity of appendiceal inflammation and post-operative stay amongst children undergoing open appendicectomy. A retrospective cohort study was conducted at a District General Hospital for two years. A total of 204 patients were included in the study with an age range between 3 and 16 years. Females were 54.9% while the rest were male. Mean age was 12.5±3 years. The association of the severity of appendiceal inflammation and post-operative stay was assessed by multivariable Cox Proportional hazards model. Mean post-operative stay was 2.32 days (95% CI 2.14–2.51). Macroscopically perforated appendix, histological inflammation and post-operative complications were significantly associated with post-operative stay on univariable analysis (P<0.05). Whereas, the multivariable analysis showed that the post-operative stay was significantly prolonged only in case of either perforated appendix or post-operative complications while it remained unaffected by the histological inflammation.

关键词： appendiceal inflammation post-operative stay paediatrics

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Improved control of hypertension following laparoscopic fundoplication for gastroesophageal reflux disease

null

《医学前沿（英文）》 2017年第11卷第1期页码 68-73 doi: 10.1007/s11684-016-0490-7

摘要：

This study aims to determine whether successful laparoscopic fundoplication for gastroesophageal reflux disease (GERD) can improve the control of hypertension. We conducted an observational study of GERD patients with hypertension. The esophageal and gastroesophageal symptoms of these patients were successfully treated with laparoscopic fundoplication, as measured by the reduced GERD symptoms and proton pump inhibitor consumption. A hypertension control scale was used to classify the use of antihypertensive medications and the quality of blood pressure control before and after anti-reflux surgery. Wilcoxon signed-ranks test was used for the statistical analyses. Seventy GERD patients were included in the analysis and followed up for a mean period of 3.5±1.4 years. Prior to surgery, all participating patients were taking at least one class of antihypertensive medication, and 56 patients (80%) had intermittently high blood pressure. After surgery, the mean number of antihypertensive medication classes per patient was significantly reduced from 1.61±0.77 pre-procedure to 1.27±0.88 post-procedure (P?<?0.001). The blood pressure of 48 of the 56 cases (86%) with preoperative intermittent high blood pressure returned to normal post procedure. A total of 50 patients (71%) recorded improvements on the hypertension control scale, with the overall mean score decreasing from 3.1±1.0 pre-procedure to 1.4±1.0 post-procedure (P?<?0.001). Therefore, successful laparoscopic fundoplication may result in better blood pressure control in some hypertensive GERD patients. This result suggests a possible connection between gastroesophageal reflux and hypertension.

关键词： gastroesophageal reflux disease hypertension blood pressure laparoscopic fundoplication

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APFD：面向移动轨迹大数据的出租车路径推荐方法 Research Article

陈卫彬1,3,陈杨杨1,2,张亚1,2

《信息与电子工程前沿（英文）》 2022年第23卷第10期页码 1511-1521 doi: 10.1631/FITEE.2100476

摘要：

本文研究了连续反馈方法在有限时间内同时实现路径跟踪和沿期望轨道编队运动控制的应用。假设虚拟领导者和跟随者之间的拓扑结构是有方向的。设计了一种称为障碍函数的附件条件，使所有智能体在一个有限的区域内移动。首先，基于障碍函数和反步法，设计了一种新型的连续有限时间路径跟踪控制算法。然后，通过将路径跟踪误差视为扰动，设计了一种新型的连续有限时间编队控制算法。详细研究了所得系统的稳定时间特性，并对所提策略进行仿真验证。

关键词：有限时间；协同路径跟踪；多智能体系统；障碍函数

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Overexpression of netrin-1 improves neurological outcomes in mice following transient middle cerebral

null

《医学前沿（英文）》 2011年第5卷第1期页码 86-93 doi: 10.1007/s11684-011-0118-x

摘要：

Netrin-1 (NT-1) is one of the axon-guiding molecules that are critical for neuronal development. Because of its structural homology to the endothelial mitogens, NT-1 may have similar effects on vascular network formation. NT-1 was shown to be able to stimulate the proliferation and migration of human cerebral endothelial cells in vitro and also promote focal neovascularization in adult brain in vivo. In the present study, we reported the delivery of NT-1 using an adeno-associated virus (AAV) vector (AAV-NT-1) into mouse brain followed by transient middle cerebral artery occlusion (tMCAO). We found that AAV vectors did not elicit a detectable inflammatory response, cell loss or neuronal damage after brain transduction. The level of NT-1 was increased in the AAV-NT-1-transduced tMCAO mice compared with the control mice. Furthermore, the neurobehavioral outcomes were significantly improved in AAV-NT-1-transduced mice compared with the control animals (P<0.05) 7 days after tMCAO. Our data suggests that NT-1 plays a neuronal function recovery role in ischemic brain and that NT-1 gene transfer might present a valuable approach to treat brain ischemic disorders.

关键词： adeno-associated virus angiogenesis gene transfer ischemia middle cerebral artery occlusion netrin-1

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c-Fos expression in rat brainstem following intake of sucrose or saccharin

Ke Chen, Jianqun Yan, Jinrong Li, Bo Lv, Xiaolin Zhao

《医学前沿（英文）》 2011年第5卷第3期页码 294-301 doi: 10.1007/s11684-011-0144-8

摘要： To examine whether the activation of brainstem neurons during intake of a sweet tastant is due to orosensory signals or post-ingestive factors, we compared the distribution of c-Fos-like immunoreactivity (c-FLI) in the nucleus of the solitary tract (NST) and parabrachial nucleus (PBN) of brainstem following ingestion of 0.25 M sucrose or 0.005 M saccharin solutions. Immunopositive neurons were localized mainly in the middle zone of the PBN and four rostral-caudal subregions of the NST. Intake of sucrose increased the number of FLI neurons in almost every subnucleus of the PBN (F = 7.610, = 0.023), in addition to the caudal NST at the level of the area postrema (F = 10.777, = 0.003) and the NST intermediate zone (F = 7.193, = 0.014). No significant increase in the number of c-Fos positive neurons was detected in response to saccharin ingestion, although there was a trend towards a modest increase in a few select NST and PBN nuclei. These results suggest that the PBN and NST may be involved in sweet taste perception and modulation of sweet tastant intake, but the significantly enhanced intensity of Fos expression induced by sucrose indicates that PBN/NST neuronal activity is driven by the integrated effects of sweet taste sensation and post-ingestive signals.

关键词： c-Fos parabrachial the nucleus of the solitary tract sweet tastant rat

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基于GIS的地震火灾动态蔓延模拟

谢旭阳,任爱珠

《中国工程科学》 2007年第9卷第8期页码 82-87

摘要：

用惠更斯原理对震后火灾的动态蔓延过程进行了模拟，并开发了基于GIS的城市地震次生火灾动态蔓延模拟系统，该系统可以模拟单个或者多个起火点的动态蔓延过程。研究结果可以定量地估计地震次生火灾对城市的危害，从而在最短时间内给救灾应急提供决策依据。

关键词：地震次生火灾 GIS 火灾动态蔓延模拟系统

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具有领航者的二阶非线性多智能体系统在外部扰动下的同步控制 None

Mao-bin LU, Lu LIU

《信息与电子工程前沿（英文）》 2019年第20卷第1期页码 88-94 doi: 10.1631/FITEE.1800611

摘要：研究了一类异质二阶非线性多智能体系统在外部扰动影响下的同步控制问题。其中，非线性系统允许包含可线性参数化的未知参数。提出一种新颖的分布式控制器，此控制器依赖于系统的相对状态，因此可以在多智能体系统之间没有通讯的情况下应用。通过Barbalat引理，证明此分布式控制器可求解二阶非线性多智能体系统的同步控制问题。对一组Van der Pol振荡器进行同步控制的应用示例验证了主要结果的有效性。

关键词：多智能体系统；同步控制；分布式控制

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物质流分析的跟踪观察法

陆钟武

《中国工程科学》 2006年第8卷第1期页码 18-25

摘要：

流动，是物质（如铜、铝等）流动和流体流动二者所具有的基本特征，基于这个论点，简要地回顾了流体力学中研究流体流动的两种方法，即拉格朗日法和欧拉法；相应地提出了物质流分析的两种方法，即跟踪观察法和定点观察法。由于前者在文献中未见报道，因此对它进行了重点说明。强调了物质流的跟踪观察法既适用于稳态物质流（产品产量不变），也适用于非稳态物质流（产品产量增长或下降）。以钢铁产品生命周期的铁流图为例，说明了物质流的跟踪模型。在引入了物质流的非稳度后，提出了物质流各项指标的计算式，以及它们之间的相互关系。以瑞典铅酸电池系统为对象，计算了其中铅流的各项指标，并进行了必要的分析。

关键词：物质流的研究方法物质流的跟踪观察法物质流的基本公式物质流的非稳度

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Challenges and opportunities in improving left ventricular remodelling and clinical outcome following

《医学前沿（英文）》 2021年第15卷第3期页码 416-437 doi: 10.1007/s11684-021-0852-7

摘要： Over the last half century, surgical aortic valve replacement (SAVR) has evolved to offer a durable and efficient valve haemodynamically, with low procedural complications that allows favourable remodelling of left ventricular (LV) structure and function. The latter has become more challenging among elderly patients, particularly following trans-catheter aortic valve implantation (TAVI). Precise understanding of myocardial adaptation to pressure and volume overloading and its responses to valve surgery requires comprehensive assessments from aortic valve energy loss, valvular-vascular impedance to myocardial activation, force-velocity relationship, and myocardial strain. LV hypertrophy and myocardial fibrosis remains as the structural and morphological focus in this endeavour. Early intervention in asymptomatic aortic stenosis or regurgitation along with individualised management of hypertension and atrial fibrillation is likely to improve patient outcome. Physiological pacing via the His-Purkinje system for conduction abnormalities, further reduction in para-valvular aortic regurgitation along with therapy of angiotensin receptor blockade will improve patient outcome by facilitating hypertrophy regression, LV coordinate contraction, and global vascular function. TAVI leaflet thromboses require anticoagulation while impaired access to coronary ostia risks future TAVI-in-TAVI or coronary interventions. Until comparable long-term durability and the resolution of TAVI related complications become available, SAVR remains the first choice for lower risk younger patients.

关键词： surgical aortic valve replacement trans-catheter aortic valve implantation left ventricular hypertrophy and fibrosis myocardial force-velocity relationship His-Purkinje pacing renin-angiotensin system inhibitors coronary access impairment

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Aerobic granulation of pure bacterial strain

ADAV Sunil S., LEE Duu-Jong

《环境科学与工程前沿（英文）》 2008年第2卷第4期页码 461-467 doi: 10.1007/s11783-008-0066-0

摘要： The objective of this study is to cultivate aerobic granules by pure bacterial strain, , in a sequencing batch reactor. Stable granules sized 2.0–2.2 mm were formed in the reactor after a five-week cultivation. These granules exhibited excellent settling attributes, and degraded phenol at rates of 1.49 and 1.19 g phenol/(g VSS·d) at 250 and 1500 mg/L of phenol concentration, respectively. Confocal laser scanning microscopic test results show that was distributed over the initial small aggregates, and the outer edge of the granule was away from the core regime in the following stage.

关键词： following excellent settling phenol/ sequencing microscopic