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期刊论文 17

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串联链路 1

免疫抑制 1

可持续发展 1

多联产 1

施马伦贝格病毒 1

无源定位;到达时间;到达频率;蒙特卡洛重要性采样;最大似然估计 1

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A neural network-based production process modeling and variable importance analysis approach in corn

《化学科学与工程前沿(英文)》 2023年 第17卷 第3期   页码 358-371 doi: 10.1007/s11705-022-2190-y

摘要: Corn to sugar process has long faced the risks of high energy consumption and thin profits. However, it’s hard to upgrade or optimize the process based on mechanism unit operation models due to the high complexity of the related processes. Big data technology provides a promising solution as its ability to turn huge amounts of data into insights for operational decisions. In this paper, a neural network-based production process modeling and variable importance analysis approach is proposed for corn to sugar processes, which contains data preprocessing, dimensionality reduction, multilayer perceptron/convolutional neural network/recurrent neural network based modeling and extended weights connection method. In the established model, dextrose equivalent value is selected as the output, and 654 sites from the DCS system are selected as the inputs. LASSO analysis is first applied to reduce the data dimension to 155, then the inputs are dimensionalized to 50 by means of genetic algorithm optimization. Ultimately, variable importance analysis is carried out by the extended weight connection method, and 20 of the most important sites are selected for each neural network. The results indicate that the multilayer perceptron and recurrent neural network models have a relative error of less than 0.1%, which have a better prediction result than other models, and the 20 most important sites selected have better explicable performance. The major contributions derived from this work are of significant aid in process simulation model with high accuracy and process optimization based on the selected most important sites to maintain high quality and stable production for corn to sugar processes.

关键词: big data     corn to sugar factory     neural network     variable importance analysis    

The critical importance of epigenetics in autoimmune-related skin diseases

《医学前沿(英文)》 2023年 第17卷 第1期   页码 43-57 doi: 10.1007/s11684-022-0980-8

摘要: Autoimmune-related skin diseases are a group of disorders with diverse etiology and pathophysiology involved in autoimmunity. Genetics and environmental factors may contribute to the development of these autoimmune disorders. Although the etiology and pathogenesis of these disorders are poorly understood, environmental variables that induce aberrant epigenetic regulations may provide some insights. Epigenetics is the study of heritable mechanisms that regulate gene expression without changing DNA sequences. The most important epigenetic mechanisms are DNA methylation, histone modification, and noncoding RNAs. In this review, we discuss the most recent findings regarding the function of epigenetic mechanisms in autoimmune-related skin disorders, including systemic lupus erythematosus, bullous skin diseases, psoriasis, and systemic sclerosis. These findings will expand our understanding and highlight the possible clinical applications of precision epigenetics approaches.

关键词: epigenetics     autoimmune-related skin diseases     DNA methylation     histone modifications     noncoding RNAs    

Recent advances in system reliability optimization driven by importance measures

Shubin SI, Jiangbin ZHAO, Zhiqiang CAI, Hongyan DUI

《工程管理前沿(英文)》 2020年 第7卷 第3期   页码 335-358 doi: 10.1007/s42524-020-0112-6

摘要: System reliability optimization problems have been widely discussed to maximize system reliability with resource constraints. Birnbaum importance is a well-known method for evaluating the effect of component reliability on system reliability. Many importance measures (IMs) are extended for binary, multistate, and continuous systems from different aspects based on the Birnbaum importance. Recently, these IMs have been applied in allocating limited resources to the component to maximize system performance. Therefore, the significance of Birnbaum importance is illustrated from the perspective of probability principle and gradient geometrical sense. Furthermore, the equations of various extended IMs are provided subsequently. The rules for simple optimization problems are summarized to enhance system reliability by using ranking or heuristic methods based on IMs. The importance-based optimization algorithms for complex or large-scale systems are generalized to obtain remarkable solutions by using IM-based local search or simplification methods. Furthermore, a general framework driven by IM is developed to solve optimization problems. Finally, some challenges in system reliability optimization that need to be solved in the future are presented.

关键词: importance measure     system performance     reliability optimization     optimization rules     optimization algorithms    

Improved resilience measure for component recovery priority in power grids

《工程管理前沿(英文)》 2021年 第8卷 第4期   页码 545-556 doi: 10.1007/s42524-021-0161-5

摘要: Given the complexity of power grids, the failure of any component may cause large-scale economic losses. Consequently, the quick recovery of power grids after disasters has become a new research direction. Considering the severity of power grid disasters, an improved power grid resilience measure and its corresponding importance measures are proposed. The recovery priority of failed components after a disaster is determined according to the influence of the failed components on the power grid resilience. Finally, based on the data from the 2019 Power Yearbook of each city in Shandong Province, China, the power grid resilience after a disaster is analyzed for two situations, namely, partial components failure and failure of all components. Result shows that the recovery priorities of components with different importance measures vary. The resilience evaluations under different repair conditions prove the feasibility of the proposed method.

关键词: resilience measure     power grid     importance measure     component recovery    

balloon-only strategy for percutaneous coronary intervention of left main coronary artery disease: the importance

《医学前沿(英文)》 2023年 第17卷 第1期   页码 75-84 doi: 10.1007/s11684-022-0950-1

摘要: This retrospective single-center registry study included all consecutive patients who underwent percutaneous coronary intervention (PCI) for a de novo left main coronary artery lesion using drug coated-balloon (DCB)-only strategy between August 2011 and December 2018. To best of our knowledge, no previous studies of DCB-only strategy of treating de novo left main coronary artery disease, exist. The primary endpoint was major adverse cardiovascular events (MACEs) including cardiac death, non-fatal myocardial infarction, and target lesion revascularization (TLR). The cohort was divided into two groups depending on weather the lesion preparation was done according to the international consensus group guidelines. Sixty-six patients (mean age 75±8.6, 72% male), 52% of whom had acute coronary syndrome, underwent left main PCI with the DCB-only strategy. No procedural mortality and no acute closures of the treated left main occurred. At 12 months, MACE and TLR occurred in 24% and 6% of the whole cohort, respectively. If the lesion preparation was done according to the guidelines, the MACE and TLR rates were 21.2% and 1.9%. Left main PCI with the DCB only-strategy is safe leading to acceptable MACE and low TLR rates at one year, if the lesion preparation is done according to the guidelines.

关键词: drug-coated balloon     left main     high bleeding risk     predilatation     calcifield lesion     percutaneous coronary intervention    

精密工程的重要性日益增加

Mark Hoffman, Liangchi Zhang

《工程(英文)》 2018年 第4卷 第6期   页码 759-759 doi: 10.1016/j.eng.2018.11.007

基于网络传输特性的链路重要性评价方法

姜禹,胡爱群,何明

《中国工程科学》 2009年 第11卷 第9期   页码 64-67

摘要:

提出了一种基于网络传输特性的链路重要性评价方法, 根据链路在网络所有节点相互通信的最短路径中的使用频度来评价链路重要性,最重要链路的使用频度最高。该方法不需要像目前的链路重要性评价方法那样进行链路收缩和删除,直接反映了链路对整个网络通信的贡献大小,可以判断通信网中任意两条链路的相对重要性。算法分析和实验仿真表明,文章算法克服了目前的评价方法存在的问题,给出了更直观合理的通信网链路重要性评价准则。

关键词: 通信网     链路重要性     最短路径     串联链路    

Emergy evaluation of polygeneration systems

WANG Lingmei, LI Zheng, NI Weidou

《能源前沿(英文)》 2007年 第1卷 第2期   页码 223-227 doi: 10.1007/s00000-007-0030-x

摘要: To expand the application range of the emergy evaluation method, an emergy evaluation index, which can reflect the particular feature of polygeneration systems, has been elaborated on the basis of energy and emergy conservation, guided by the fundamental principle of emergy analysis. With this index, the cost structure, emission effect and energy saved were all considered on the same level of importance. To exemplify, some power polygeneration systems (methanol-power generation, hydrogen-power generation) are considered using coal as the basic fuel. The results showed that emergy evaluation indices are practical for comprehensively evaluating polygeneration systems and their sustainability, which is influenced by such factors as the joining mode of polygeneration and the technologies used. The sustainability of polygeneration systems, which work on an appropriate ratio of fuel-to-electric power basis, is higher than that of singular production systems.

关键词: fuel-to-electric     sustainability     importance     polygeneration     practical    

基于重要性采样的TOA与FOA无源定位算法 Article

Rui-rui LIU, Yun-long WANG, Jie-xin YIN, Ding WANG, Ying WU

《信息与电子工程前沿(英文)》 2017年 第18卷 第8期   页码 1167-1179 doi: 10.1631/FITEE.1601657

摘要: 最大似然类的无源定位方法可以达到较高的定位精度,但其计算量非常大。由于时频参数联合定位模型本身的非线性和非凸性非常大,繁重的计算量在TOA与FOA联合定位系统中表现尤为明显。本文针对这一问题,通过Pincus全局最优理论和蒙特卡洛重要性采样技术降低了最大似然类定位算法的计算复杂度,并且保证算法可以收敛到全局最优解。本文主要的贡献是构建了一个高斯分布的概率密度函数来近似原始的代价函数方便后续的采样,我们称之为重要性函数。该方法所带来性能上的提升是因为选择了最优的重要性函数并且Pincus保证算法收敛到全局最小值。这一处理大大降低了计算量,由于算法进行了泰勒级数展开,需要初始估计值。通过采样处理并且对样本进行加权,本文算法对初始估计值具有良好的鲁棒性。最后,实验证明本文所提算法可以达到克拉美罗限,且性能要优于现有算法。

关键词: 无源定位;到达时间;到达频率;蒙特卡洛重要性采样;最大似然估计    

Importance of emulsions in crystallization—applications for fat crystallization

Sandra PETERSEN, K. CHALEEPA, Joachim ULRICH

《化学科学与工程前沿(英文)》 2013年 第7卷 第1期   页码 43-48 doi: 10.1007/s11705-013-1309-6

摘要: Emulsions and crystallization are two independent research topics which normally do not overlap although a combination of the two could be applicable to many areas. Here, the importance of emulsions in the field of fat crystallization is described. Three applications with industrial relevance were chosen for investigation: fat fractionation, the solidification of phase change materials and solid lipid nanoparticles. For fat fractionation and phase change materials, emulsification can be applied as a tool to improve the fat crystallization process, and thus the product quality of the crystallized fat. Furthermore, the use of emulsification creates new application fields such as solid lipid nanoparticles in the area of fat crystallization.

关键词: emulsion     fat crystallization     phase change material     emulsion fractionation     emulsion solidification    

用于电网节点重要度评估的一种基于网络嵌入和支持向量回归的人工智能方法 Research Papers

Hui-fang WANG, Chen-yu ZHANG, Dong-yang LIN, Ben-teng HE

《信息与电子工程前沿(英文)》 2019年 第20卷 第6期   页码 816-828 doi: 10.1631/FITEE.1800146

摘要: 重要节点识别对电网安全意义重大。但电网在规模、结构等方面差异较大,评价指标难以涵盖电网不同状态下所有信息,因此基于指标构建的传统评估方法,其效果视情况而定,通用性不足。由此,本文提出基于人工智能的电网节点重要度评估法。首先利用网络嵌入,提出综合考虑电网结构与电气量的电网节点特征选择法。然后对具体电网,进行各类运行方式下的稳态与节点故障暂态仿真,构建能反映节点特征与节点重要度内在关系的样本集。最后,根据优化后的样本集训练支持向量回归模型,模型成熟后可用于电网节点重要度在线评估。结果表明,本方法能根据从样本中学到的信息有效评估电网节点重要度。相比传统指标构建法,本方法规避了片面性和主观性。此外,基于该人工智能框架,本方法可针对每个具体电网建立特定样本集,具有通用性。

关键词: 电网;人工智能;节点重要度;TADW法;网络嵌入;支持向量回归    

Development and utilization of underground space for the protection of relics in the Yang Emperor Mausoleum of the Han Dynasty

CHEN Zhilong, ZHANG Ping, LI Juxi

《结构与土木工程前沿(英文)》 2007年 第1卷 第2期   页码 229-233 doi: 10.1007/s11709-007-0028-9

摘要: By analyzing the ten burials that have been unearthed at the Yang Emperor Mausoleum of the Han Dynasty, and China s first wholly underground protection and exhibition hall of relics that is under construction, the article expounds the importance of relic site protection through underground space. In particular, it discusses the preservation of historical and cultural relics, the harmonious relationship between architecture and nature, and the collection and security of cultural relics.

关键词: importance     architecture     preservation     harmonious relationship     construction    

Analysis of statistical thermodynamic model for binary protein adsorption equilibria on cation exchange adsorbent

ZHOU Xiaopeng, SU Xueli, SUN Yan

《化学科学与工程前沿(英文)》 2007年 第1卷 第2期   页码 103-112 doi: 10.1007/s11705-007-0020-x

摘要: A study of nonlinear competitive adsorption equilibria of proteins is of fundamental importance in understanding the behavior of preparative chromatographic separation. This work describes the nonlinear binary protein adsorption equilibria on ion exchangers by the statistical thermodynamic (ST) model. The single-component and binary protein adsorption isotherms of bovine hemoglobin (Hb) and bovine serum albumin (BSA) on SP Sepharose FF were determined by batch adsorption experiments in 0.05 mol/L sodium acetate buffer at three pH values (4.5, 5.0 and 5.5) and three NaCl concentrations (0.05, 0.10 and 0.15 mol/L) at pH 5.0. The ST model was found to depict the effects of pH and ionic strength on the single-component equilibria well, with model parameters depending on the pH and ionic strength. Moreover, the ST model gave acceptable fitting to the binary adsorption data with the fitted single-component model parameters, leading to the estimation of the binary ST model parameter. The effects of pH and ionic strength on the model parameters are reasonably interpreted by the electrostatic and thermodynamic theories. Results demonstrate the availability of the ST model for describing nonlinear competitive protein adsorption equilibria in the presence of two proteins.

关键词: fundamental importance     single-component equilibria     acceptable fitting     hemoglobin     chromatographic separation    

绿色供热系统——经济建设中的重大课题

宋之平

《中国工程科学》 2001年 第3卷 第6期   页码 9-14

摘要:

提出了一个术语“绿色供热系统”,并阐述了它应有的特征。为此,介绍了可逆型供热系统的概念和一般化供热系统模型。为了界定绿色供热系统,使用了作者设计的《单耗分析》的理论和方法。基于绿色供热系统所界定的原则,把排放物的量和有害成分大幅度地降下来的供热方案具有现实的可行性,如再与诸如蒸馏法海水淡化等技术相结合,不但具有可持续的发展空间,单就其可能产生的水量、水质以及造水成本而言,均堪与流域调水方案相竞争。

关键词: 可持续发展     水资源     热电联产     热泵     多联产    

Comprehensive evaluation of heavy metal contamination of sediment in Lake Dianchi by using modified AHP method and Cs dating

ZHANG Yan, GAO Xiang, ZHONG Zhenyu, PENG Buzhuo, DENG Xihai

《环境科学与工程前沿(英文)》 2008年 第2卷 第3期   页码 370-379 doi: 10.1007/s11783-008-0054-4

摘要: Through the use of general sampling and measurement by Cs dating, problems regarding the absence of monitoring data can easily be resolved. Further, weighted values need to be determined while Environment Quality Comprehensive Index (EQCI) is commonly used as applied in environmental quality comprehensive evaluation. In order to overcome the subjectivity in determining weights, the modified Analytical Hierarchy Process (AHP) method was designed. The modified AHP method involved the following key procedures: First, the parameters and were calculated based on the monitoring data; second, the factors were put in order according to the symbol and value of and ; third, the continuous odd integers, which represented the importance of factors, were given to factors according to their seating order; and, fourth, the factor weights were determined from the pair-wise comparison matrix calculated by the ratio of the given odd integers. Therefore, the weights were completely based on the monitoring data. In the present study, the comprehensive quality of sediments in five sections of Lake Dianchi were evaluated and the results indicated that the current contamination of sediments in each lake section is much more serious than at any other time in history.

关键词: Dianchi     Analytical Hierarchy     monitoring     modified Analytical     importance    

标题 作者 时间 类型 操作

A neural network-based production process modeling and variable importance analysis approach in corn

期刊论文

The critical importance of epigenetics in autoimmune-related skin diseases

期刊论文

Recent advances in system reliability optimization driven by importance measures

Shubin SI, Jiangbin ZHAO, Zhiqiang CAI, Hongyan DUI

期刊论文

Improved resilience measure for component recovery priority in power grids

期刊论文

balloon-only strategy for percutaneous coronary intervention of left main coronary artery disease: the importance

期刊论文

精密工程的重要性日益增加

Mark Hoffman, Liangchi Zhang

期刊论文

基于网络传输特性的链路重要性评价方法

姜禹,胡爱群,何明

期刊论文

Emergy evaluation of polygeneration systems

WANG Lingmei, LI Zheng, NI Weidou

期刊论文

基于重要性采样的TOA与FOA无源定位算法

Rui-rui LIU, Yun-long WANG, Jie-xin YIN, Ding WANG, Ying WU

期刊论文

Importance of emulsions in crystallization—applications for fat crystallization

Sandra PETERSEN, K. CHALEEPA, Joachim ULRICH

期刊论文

用于电网节点重要度评估的一种基于网络嵌入和支持向量回归的人工智能方法

Hui-fang WANG, Chen-yu ZHANG, Dong-yang LIN, Ben-teng HE

期刊论文

Development and utilization of underground space for the protection of relics in the Yang Emperor Mausoleum of the Han Dynasty

CHEN Zhilong, ZHANG Ping, LI Juxi

期刊论文

Analysis of statistical thermodynamic model for binary protein adsorption equilibria on cation exchange adsorbent

ZHOU Xiaopeng, SU Xueli, SUN Yan

期刊论文

绿色供热系统——经济建设中的重大课题

宋之平

期刊论文

Comprehensive evaluation of heavy metal contamination of sediment in Lake Dianchi by using modified AHP method and Cs dating

ZHANG Yan, GAO Xiang, ZHONG Zhenyu, PENG Buzhuo, DENG Xihai

期刊论文