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Cooling strategies and transport theories for brain hypothermia resuscitation

LIU Jing

《能源前沿（英文）》 2007年 第1卷 第1期   页码 32-57 doi: 10.1007/s11708-007-0004-z

摘要： The brain is one of the most important organs in a biological body whose normal function depends heavily on an uninterrupted delivery of oxygen. Unlike skeletal muscles that can survive for hours without oxygen, neuron cells in the brain are easily subjected to an irreversible damage within minutes from the onset of oxygen deficiency. With the interruption of cardiopulmonary circulation in many cardiac surgical procedures or accidental events leading to cerebral circulation arrest, an imbalance between energy production and consumption will occur which causes a rapid depletion of oxygen due to the interrupted blood-flow to the brain. Meanwhile, the cooling function of the blood flow on the hot tissue will be stopped, while metabolic heat generation in the tissues still keeps running for awhile. Under such adverse situations, the potential for cerebral protection through hypothermia has been intensively investigated in clinics by lowering brain temperature to restrain the cerebral oxygen demands. The reason can be attributed to the decreased metabolic requirements of the cold brain tissues, which allows a longer duration for the brain to endure reduced oxygen delivery. It is now clear that hypothermia would serve as the principal way for neurologic protection in a wide variety of emergency medicines, especially in cerebral damage, anoxia, circulatory arrest, respiratory occlusion, etc. However, although brain cooling has been found uniquely significant in clinical practices, the serious lack of knowledge on the mechanisms involved prevents its further advancement in brain resuscitation. Compared with the expanded trials in clinics, only very limited efforts were made to probe the engineering issues involved, which turns out to be a major obstacle for the successful operation of brain hypothermia resuscitation. From the viewpoint of biothermal medical engineering, the major theories and strategies for administering brain cooling can generally be classified into three categories: heat transfer, oxygen transport and cooling strategy. Aiming to provide a complete overview of the brain hypothermia resuscitation, this article comprehensively summarizes the recent progresses made in theoretical, practical and experimental techniques in the area. Particularly, attention is paid to the mathematical models to quantify the heat and oxygen transport inside the cerebral tissues. Typical cooling strategies to effectively lower brain temperature and thus decrease oxygen consumption rate in the cerebral tissues are analyzed. Approaches to deliver oxygen directly to the target tissues are discussed. Meanwhile, some future efforts worth pursuing within the area of brain cooling are suggested.

关键词： mathematical     interruption     hypothermia     metabolic     generation    

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Breeding strategies for increasing yield potential in super hybrid rice

Shihua CHENG,Xiaodeng ZHAN,Liyong CAO

《农业科学与工程前沿（英文）》 2015年 第2卷 第4期   页码 277-282 doi: 10.15302/J-FASE-2015081

摘要： Super hybrid rice breeding is a new breeding method combining semi-dwarf breeding and heterosis breeding using germplasm and gene-environment interactions. This paper reviews the breeding strategies of super hybrid rice breeding in China, focusing on the utilization of heterosis of indica and japonica subspecies, construction of ideal plant architecture and pyramiding of disease resistant genes in restorer lines. To develop super hybrid rice, considerable effort should be made to explore genes related with high yield, good quality, resistance to pests and diseases, tolerance to stresses. Molecular breeding methods in combination with crossing techniques should be adopted in super hybrid rice breeding.

关键词： super hybrid rice     breeding strategies     yield potential    

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USING NUTRITIONAL STRATEGIES TO MITIGATE RUMINAL METHANE EMISSIONS FROM RUMINANTS

《农业科学与工程前沿（英文）》 2023年 第10卷 第3期   页码 390-402 doi: 10.15302/J-FASE-2023504

摘要：

● Microbial fermentation in the rumen is a main source of methane emissions.

关键词： nutritional strategy     mitigation     microbe     methane     ruminant    

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Management strategies of marine food resources under multiple stressors with particular reference of

Qisheng TANG

《农业科学与工程前沿（英文）》 2014年 第1卷 第1期   页码 85-90 doi: 10.15302/J-FASE-2014021

摘要：

In this study two main management strategies are discussed: one is to develop resource conservation-based capture fisheries, and the other is to develop environmentally friendly aquaculture. During the resource recovery period, the development of environmentally friendly aquaculture should be encouraged, especially in integrated multi-trophic aquaculture, which is adaptive, efficient and sustainable. For future development and better understanding the ecosystem, it is necessary to further strengthen basic research.

关键词： marine     ecosystem     management strategies     food resources     Yellow Sea    

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Basic consideration of research strategies for head and neck cancer

null

《医学前沿（英文）》 2012年 第6卷 第4期   页码 339-353 doi: 10.1007/s11684-012-0213-7

摘要：

Head and neck cancer (HNC) consists of a group of malignancies affecting closely related anatomical regions of the upper aerodigestive tract (UADT), including the oral cavity, salivary glands, upper and lower jaw bones and facial skin; the nasal cavity, paranasal sinuses, pharynx, larynx and thyroid gland (although the latter is often excluded and considered as part of endocrine neoplasms). Of these, 90% of HNCs are histologically squamous cell carcinomas originating from the mucosal lining. These malignancies are strongly associated with certain environmental and life-style risk factors, principally tobacco in both smoked and smokeless forms, excessive alcohol consumption, diets poor in antioxidants and essential micronutrients, UV light, chemicals used in certain workplaces, and viruses, principally certain strains of human papillomavirus (HPV) and Epstein-Barr virus (EBV). These cancers are frequently aggressive in their biological behaviour with local invasion and metastasis to lymph nodes in the neck. Since most patients are already at late stages of disease at the time of diagnosis, the desirable practice of early diagnosis (first sign of the malignant lesion at an initial stage ) and early treatment, a critical priority to save lives and retain quality of life, is difficult to implement. Thus, primary prevention has been set as a key goal. This article aims to reinforce the basic knowledge of aetiology, key risk factors related to the development of head and neck cancer, basic features of clinical appearance of this group of cancers, and strategies for prevention and early detection. We also suggest basic research strategies on the basis of current knowledge, which should ultimately lead to the improvement of clinical management.

关键词： clinical management     head and neck cancer     prevention and early detection     research strategies     risk factors    

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Emergency strategies and trends in the management of liver trauma

null

《医学前沿（英文）》 2012年 第6卷 第3期   页码 225-233 doi: 10.1007/s11684-012-0186-6

摘要：

The liver is the most frequently injured organ during abdominal trauma. The management of hepatic trauma has undergone a paradigm shift over the past several decades, with mandatory operation giving way to nonoperative treatment. Better understanding of the mechanisms and grade of liver injury aids in the initial assessment and establishment of a management strategy. Hemodynamically unstable patients should undergo focused abdominal sonography for trauma, whereas stable patients may undergo computed tomography, the standard examination protocol. The grade of liver injury alone does not accurately predict the need for operation, and nonoperative management is rapidly becoming popular for high-grade injuries. Hemodynamic instability with positive focused abdominal sonography for trauma and peritonitis is an indicator of the need for emergent operative intervention. The damage control concept is appropriate for the treatment of major liver injuries and is associated with significant survival advantages compared with traditional prolonged surgical techniques. Although surgical intervention for hepatic trauma is not as common now as it was in the past, current trauma surgeons should be familiar with the emergency surgical skills necessary to manage complex hepatic injuries, such as packing, Pringle maneuver, selective vessel ligation, resectional debridement, and parenchymal sutures. The present review presents emergency strategies and trends in the management of liver trauma.

关键词： liver trauma     nonoperative management     operative management    

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Exploring differentiated improvement strategies of cultivated land quality in China

《农业科学与工程前沿（英文）》 doi: 10.15302/J-FASE-2023523

摘要：

● Cultivated land quality can be considered in four dimensions: suitability, contiguity, resistance, and ecological stress.

关键词： China     cultivated land quality     differentiated improvement     food security    

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Microplastics removal strategies: A step toward finding the solution

《环境科学与工程前沿（英文）》 2022年 第16卷 第1期   页码 7-7 doi: 10.1007/s11783-021-1441-3

摘要：

Microplastics are an emerging threat and a big challenge for the environment. The presence of microplastics (MPs) in water is life-threatening to diverse organisms of aquatic ecosystems. Hence, the scientific community is exploring deeper to find treatment and removal options of MPs. Various physical, chemical and biological methods are researched for MPs removal, among which few have shown good efficiency in the laboratory. These methods also have a few limitations in environmental conditions. Other than finding a suitable method, the creation of legal restrictions at a governmental level by imposing policies against MPs is still a daunting task in many countries. This review is an effort to place all effectual MP removal methods in one document to compare the mechanisms, efficiency, advantages, and disadvantages and find the best solution. 

关键词： Aquatic     Coagulation     Microplastics     Plastic     Water Treatment Plant     Wastewater    

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Emerging immunological strategies: recent advances and future directions

《医学前沿（英文）》 2021年 第15卷 第6期   页码 805-828 doi: 10.1007/s11684-021-0886-x

摘要： Immunotherapy plays a compelling role in cancer treatment and has already made remarkable progress. However, many patients receiving immune checkpoint inhibitors fail to achieve clinical benefits, and the response rates vary among tumor types. New approaches that promote anti-tumor immunity have recently been developed, such as small molecules, bispecific antibodies, chimeric antigen receptor T cell products, and cancer vaccines. Small molecule drugs include agonists and inhibitors that can reach the intracellular or extracellular targets of immune cells participating in innate or adaptive immune pathways. Bispecific antibodies, which bind two different antigens or one antigen with two different epitopes, are of great interest. Chimeric antigen receptor T cell products and cancer vaccines have also been investigated. This review explores the recent progress and challenges of different forms of immunotherapy agents and provides an insight into future immunotherapeutic strategies.

关键词： cancer immunotherapy     bispecific antibodies     small molecules     chimeric antigen receptor T therapy     cancer vaccines    

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Pricing and production strategies in remanufacturing from the perspectives of supply chain: Review and

《工程管理前沿（英文）》 doi: 10.1007/s42524-023-0251-7

摘要： Remanufacturing is widely recognized as beneficial to the environment and a circular economy. However, remanufacturing is more complex than traditional manufacturing due to the effects of government policy, uncertainty of consumer preferences, competition and cooperation among firms, and so on. These factors motivate academics to optimize remanufacturing outcomes, especially for product pricing and production. This study reviews the published literature on pricing and production strategies in remanufacturing from four perspectives of supply chain, namely, government policy, consumer characteristics, relationships among firms, and supply chain structures. Review results can benefit scholars/practitioners in the future by highlighting the challenges and opportunities in remanufacturing strategies.

关键词： remanufacturing     reverse and closed-loop supply chain     circular economy    

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Control strategies for disinfection byproducts by ion exchange resin, nanofiltration and their sequential

《环境科学与工程前沿（英文）》 2023年 第17卷 第10期 doi: 10.1007/s11783-023-1725-x

摘要：

● Effects of AER adsorption and NF on DBP precursors, DBPs, and TOX were examined.

关键词： Disinfection byproducts     Control     Anion exchange resin     Nanofiltration     Cytotoxicity    

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Systematical strategies for wastewater treatment and the generated wastes and greenhouse gases in China

Jingbo GUO, Fang MA, Yuanyuan QU, Ang LI, Liang WANG

《环境科学与工程前沿（英文）》 2012年 第6卷 第2期   页码 271-279 doi: 10.1007/s11783-011-0328-0

摘要： China now faces double challenges of water resources shortage and severe water pollution. To resolve Chinese water pollution problems and reduce its impacts on human health, economic growth and social development, the situation of wastewater treatment was investigated. Excess sludge and greenhouse gases (GHGs) emitted during wastewater treatment were also surveyed. It is concluded that Chinese water pollution problems should be systematically resolved with inclusion of wastewater and the solid waste and GHGs generated during wastewater treatment. Strategies proposed for the wastewater treatment in China herein were also adequate for other countries, especially for the developing countries with similar economic conditions to China.

关键词： wastewater treatment     solid waste     greenhouse gases     systematical strategies    

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Urban agriculture as nature-based solutions: Three key strategies to tackle emerging issues on food security

《工程管理前沿（英文）》   页码 736-741 doi: 10.1007/s42524-023-0262-4

摘要： Urban agriculture as nature-based solutions: Three key strategies to tackle emerging issues on food security in Chinese cities under climatic and non-climatic challenges

关键词： key strategies tackle     Urban agriculture nature     challenges    

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WHEAT STRIPE RUST AND INTEGRATION OF SUSTAINABLE CONTROL STRATEGIES IN CHINA

《农业科学与工程前沿（英文）》 2022年 第9卷 第1期   页码 37-51 doi: 10.15302/J-FASE-2021405

摘要：

Stripe (yellow) rust caused by Puccinia striiformis f. sp. tritici occurs in almost all wheat-producing regions of the world. Severe countrywide epidemics in China have caused substantial yield losses. Growing resistant cultivars is the best strategy to control this disease but the pathogen can overcome resistance in wheat cultivars. The high variation in the virulence of the pathogen combined with the large areas of susceptible wheat cultivars enables the pathogen population to increase rapidly and disperse over long distances under favorable environmental conditions, resulting in severe pandemics within cropping seasons. Current stripe rust control measures are based on many years of research including the underlying epidemiology regarding year-to-year survival of the pathogen, pathways of pathogen dispersal within seasons and years, the role of P. striiformis sexual hybridization, the use of resistance sources in breeding programs, and year-round surveillance of national wheat crops that are present in different parts of the country throughout the year. All these strategies depend on accurate prediction of epidemics, more precise use of fungicides to meet national requirements and better deployment of resistance genes. New ideas with potential application in sustainable protection of stripe rust include negative regulatory gene editing, resistance gene overexpression and biological control based on microbiomes.

 

关键词： sustainable disease control / integrated control Puccinia striiformis / Triticum aestivum    

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Anti-biofouling strategies for implantable biosensors of continuous glucose monitoring systems

《化学科学与工程前沿（英文）》 2023年 第17卷 第12期   页码 1866-1878 doi: 10.1007/s11705-023-2340-x

摘要： Continuous glucose monitoring (CGM) systems play an increasingly vital role in the glycemic control of patients with diabetes mellitus. However, the immune responses triggered by the implantation of poorly biocompatible sensors have a significant impact on the accuracy and lifetime of CGM systems. In this review, research efforts over the past few years to mitigate the immune responses by enhancing the anti-biofouling ability of sensors are summarized. This review divided these works into active immune engaging strategy and passive immune escape strategy based on their respective mechanisms. In each strategy, the various biocompatible layers on the biosensor surface, such as drug-releasing membranes, hydrogels, hydrophilic membranes, anti-biofouling membranes based on zwitterionic polymers, and bio-mimicking membranes, are described in detail. This review, therefore, provides researchers working on implantable biosensors for CGM systems with vital information, which is likely to aid in the research and development of novel CGM systems with profound anti-biofouling properties.

关键词： implantable glucose biosensor     anti-biofouling     continuous glucose monitoring     immune responses    

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标题 作者 时间 类型 操作

Cooling strategies and transport theories for brain hypothermia resuscitation

LIU Jing

期刊论文

Breeding strategies for increasing yield potential in super hybrid rice

Shihua CHENG,Xiaodeng ZHAN,Liyong CAO

期刊论文

USING NUTRITIONAL STRATEGIES TO MITIGATE RUMINAL METHANE EMISSIONS FROM RUMINANTS

期刊论文

Management strategies of marine food resources under multiple stressors with particular reference of

Qisheng TANG

期刊论文

Basic consideration of research strategies for head and neck cancer

null

期刊论文

Emergency strategies and trends in the management of liver trauma

null

期刊论文

Exploring differentiated improvement strategies of cultivated land quality in China

期刊论文

Microplastics removal strategies: A step toward finding the solution

期刊论文

Emerging immunological strategies: recent advances and future directions

期刊论文

Pricing and production strategies in remanufacturing from the perspectives of supply chain: Review and

期刊论文

Control strategies for disinfection byproducts by ion exchange resin, nanofiltration and their sequential

期刊论文

Systematical strategies for wastewater treatment and the generated wastes and greenhouse gases in China

Jingbo GUO, Fang MA, Yuanyuan QU, Ang LI, Liang WANG

期刊论文

Urban agriculture as nature-based solutions: Three key strategies to tackle emerging issues on food security

期刊论文

WHEAT STRIPE RUST AND INTEGRATION OF SUSTAINABLE CONTROL STRATEGIES IN CHINA

期刊论文

Anti-biofouling strategies for implantable biosensors of continuous glucose monitoring systems

期刊论文