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人参皂苷CK 1

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人参皂苷CK﹑淫羊藿苷对体外培养精子的剂量负荷试验

余宏亮,常明秀,曹恒海,薄立伟,杨永俊,李聪敏,李铭

《中国工程科学》 2015年第17卷第6期页码 86-88

摘要：

目的：项目拟通过观察在培养液中加入较高剂量的人参皂苷CK（Ginsenoside，G组）、淫羊藿苷（Icraiin，I组）两种药物前﹑后精子死亡率数据，评估两种药物单体在较大剂量时对体外精子的死亡率的影响方法：新鲜液化的精液（semen）标本40份，F-10培养液调整浓度为1.0×107/mL，分别添加不同剂量的人参皂苷CK（Ginsenoside，Gin CK）﹑淫羊藿苷（Icraiin，结论：较大剂量的Gin CK、Icr，均可引起体外培养的精子死亡率增高；在0.1 mg/mL的浓度下的Gin CK对精子的致死作用已经比较明显，而0.5 mg/mL对体外培养精子来说是致死剂量（98.84%），在0.1 mg/mL的剂量下的淫羊藿苷对精子的致死作用并不明显，在0.5 mg/mL剂量下Icr对精子致死作用有所提高，但远未达到Gin CK 98.4%的致死率。

关键词：人参皂苷CK 淫羊藿苷精子致死剂量

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Synchronous rectal adenocarcinoma and anal canal adenocarcinoma

GU Jin, YAO Yunfeng, LI Jiyou, LU Aiping, WANG Hongyi

《医学前沿（英文）》 2007年第1卷第3期页码 333-337 doi: 10.1007/s11684-007-0064-9

摘要： It is difficult to distinguish a rectal carcinoma with anal metastases from coexistent synchronous anorectal carcinomas. The therapeutic strategy for rectal and anal carcinoma is so different that it should be clearly identified. Here, we report on the case of a 63-year-old man who presented with an upper-third rectal adenocarcinoma. Five months after resection, he developed an adenocarcinoma in the anal canal. The histological slides of both tumors were reviewed and immunohistochemical studies for cytokeratins (CKs) 7 and 20 were performed. The index tumor demonstrated CK 7 /CK 20+ and the second showed CK7+/CK20+. For this reason, we believe the present case had synchronous adenocarcinomas arising from anal canal and the rectum separately. It is very important to differentiate the anorectal lesions pathologically because of the impact on the therapeutic options available, especially for the lesion arising in the anal canal.

关键词： CK7+/CK20+ resection different therapeutic strategy upper-third