Search | Engineering

订阅投稿

首页工程期刊工程焦点工程成就工程前沿关于我们 English

资源类型

会议视频 108

期刊论文 68

会议信息 5

年份

2023 10

2022 88

2021 36

2020 5

2019 5

2018 1

2017 3

2016 4

2015 2

2014 1

2013 2

2012 4

2011 3

2010 1

2009 2

2008 4

2007 3

2005 1

2002 2

1999 1

展开︾

关键词

能源 29

颠覆性技术 14

农业科学 13

环境 11

汽车 10

桥梁工程 9

医学 5

工程管理 5

组织工程 5

智能制造 3

生物材料 2

经济 2

营养健康 2

20 kt级重载组合列车 1

2020 1

20世纪 1

ARM7 1

Engineering期刊工作 1

H7N9 1

展开︾

检索范围：

排序：展示方式：

Synchronous rectal adenocarcinoma and anal canal adenocarcinoma

GU Jin, YAO Yunfeng, LI Jiyou, LU Aiping, WANG Hongyi

《医学前沿（英文）》 2007年第1卷第3期页码 333-337 doi: 10.1007/s11684-007-0064-9

摘要： It is difficult to distinguish a rectal carcinoma with anal metastases from coexistent synchronous anorectal carcinomas. The therapeutic strategy for rectal and anal carcinoma is so different that it should be clearly identified. Here, we report on the case of a 63-year-old man who presented with an upper-third rectal adenocarcinoma. Five months after resection, he developed an adenocarcinoma in the anal canal. The histological slides of both tumors were reviewed and immunohistochemical studies for cytokeratins (CKs) 7 and 20 were performed. The index tumor demonstrated CK 7 /CK 20+ and the second showed CK7+/CK20+. For this reason, we believe the present case had synchronous adenocarcinomas arising from anal canal and the rectum separately. It is very important to differentiate the anorectal lesions pathologically because of the impact on the therapeutic options available, especially for the lesion arising in the anal canal.

关键词： CK7+/CK20+ resection different therapeutic strategy upper-third

HTML PDF 收藏

人参皂苷CK﹑淫羊藿苷对体外培养精子的剂量负荷试验

余宏亮,常明秀,曹恒海,薄立伟,杨永俊,李聪敏,李铭

《中国工程科学》 2015年第17卷第6期页码 86-88

摘要：

目的：项目拟通过观察在培养液中加入较高剂量的人参皂苷CK（Ginsenoside，G组）、淫羊藿苷（Icraiin，I组）两种药物前﹑后精子死亡率数据，评估两种药物单体在较大剂量时对体外精子的死亡率的影响方法：新鲜液化的精液（semen）标本40份，F-10培养液调整浓度为1.0×107/mL，分别添加不同剂量的人参皂苷CK（Ginsenoside，Gin CK）﹑淫羊藿苷（Icraiin，结论：较大剂量的Gin CK、Icr，均可引起体外培养的精子死亡率增高；在0.1 mg/mL的浓度下的Gin CK对精子的致死作用已经比较明显，而0.5 mg/mL对体外培养精子来说是致死剂量（98.84%），在0.1 mg/mL的剂量下的淫羊藿苷对精子的致死作用并不明显，在0.5 mg/mL剂量下Icr对精子致死作用有所提高，但远未达到Gin CK 98.4%的致死率。

关键词：人参皂苷CK 淫羊藿苷精子致死剂量

HTML PDF 收藏

Nonlinear dynamic analysis of functionally graded carbon nanotube-reinforced composite plates using MISQ20

《结构与土木工程前沿（英文）》页码 1072-1085 doi: 10.1007/s11709-023-0951-4

摘要： The main objective of this study is to further extend the mixed integration smoothed quadrilateral element with 20 unknowns of displacement (MISQ20) to investigate the nonlinear dynamic responses of functionally graded carbon nanotube-reinforced composite (FG-CNTRC) plates with four types of carbon nanotube distributions. The smooth finite element method is used to enhance the accuracy of the Q4 element and avoid shear locking without using any shear correction factors. This method yields accurate results even if the element exhibits a concave quadrilateral shape and reduces the error when the element meshing is rough. Additionally, the element stiffness matrix is established by integrating the boundary of the smoothing domains. The motion equation of the FG-CNTRC plates is solved by adapting the Newmark method combined with the Newton–Raphson algorithm. Subsequently, the calculation program is coded in the MATLAB software and verified by comparing it with other published solutions. Finally, the effects of the input parameters on the nonlinear vibration of the plates are investigated.

关键词： carbon nanotube MISQ20 FG-CNTRC plate nonlinear vibration nonlinear dynamic analysis SFEM

HTML PDF 收藏

Rolling-element bearings in China: From ancient times to the 20th century

Lie SUN,Ang LI

《机械工程前沿（英文）》 2016年第11卷第1期页码 33-43 doi: 10.1007/s11465-016-0373-2

摘要：

The development of rolling-element bearings in China has spanned a long period. Based on several typical and important cases, the present article reconstructs the history of rolling-element bearings in China by dividing it into four stages according to the various characteristics of the bearings. The first stage represents the origin of rolling bearings in China, which remains controversial because of several suspected races and cages that were likely the components of bearings more than a millennium ago. At the second stage, a type of simple roller bearing was used for astronomical instruments not later than the 13th century based on clear philological and physical evidence. A similar bearing was also applied to an abridged armillary in the 17th century. Another type of spherical thrust bearings with rolling elements, which is a key component of a traditional Chinese windmill, could support a rotating shaft that moves rotationally and at an angle. At the third stage, the Chinese began studying and using the so-called European-style bearing since the 17th century. Moreover, over the last 100 years, the modern rolling bearing industry was gradually established in China, particularly because of the technology transfer from the Soviet Union in the 1950s. At the fourth stage, the Chinese government initiated the relatively rapid development of bearing technology. The government launched the “bearing movement” from the 1950s to the 1960s to establish the modern bearing industry and to promote rolling bearings as replacement for traditional sliding bearings. Furthermore, a number of large professional factories and institutions in China have continually introduced advanced technology and equipment. At present, these companies and institutions play a significant role in the international bearing industry.

关键词： bearing movement rolling-element bearing China early rolling bearings technology transfer

HTML PDF 收藏

“20世纪我国重大工程技术成就” 评选结果在京揭晓

null

《中国工程科学》 2002年第4卷第1期页码 94-94

HTML PDF 收藏

Resistance of large deformation of the Wushaoling Tunnel F7 soft fault

ZHAO Xufeng, CHEN Haiming, WANG Chunmiao

《结构与土木工程前沿（英文）》 2007年第1卷第1期页码 123-127 doi: 10.1007/s11709-007-0013-3

摘要： In this article, the mechanical characteristics of the squeeze of the F7 fault of the Wushaoling Tunnel are analyzed. The measurements and techniques are proposed to resist the deformation. The result indicates that the method of construction to control the further squeeze deflection is appropriate.

关键词： F7 deformation appropriate construction mechanical

HTML PDF 收藏

中国工程科学2005年第7卷总目次

null

《中国工程科学》 2005年第7卷第12期页码 98-102

HTML PDF 收藏

Acid Orange 7 degradation using methane as the sole carbon source and electron donor

《环境科学与工程前沿（英文）》 2022年第16卷第3期 doi: 10.1007/s11783-021-1468-5

摘要：

• AO7 degradation was coupled with anaerobic methane oxidation.

关键词： Azo dyes AO7 degradation Anaerobic methane oxidation Microbial community ANME-2d

HTML PDF 收藏

ORGANIC CARBON STOCKS IN A SILTY TEXTURED SOIL FOLLOWING REINTEGRATION OF A 20 YEARS OLD × SITE INTO

《农业科学与工程前沿（英文）》 2023年第10卷第2期页码 183-197 doi: 10.15302/J-FASE-2023485

摘要：

● 0.98 Mg·ha⁻¹·yr⁻¹ C_org accumulation under miscanthus over 26 years.

关键词： biobased energy crops C balance humus accumulation

HTML PDF 收藏

Time-dependent metabolomics uncover dynamic metabolic adaptions in MCF-7 cells exposed to bisphenol A

《环境科学与工程前沿（英文）》 2023年第17卷第1期 doi: 10.1007/s11783-023-1604-5

摘要：

● Metabolomic temporal profiling of cells exposed to xenobiotics.

关键词： Metabolomics BPA MCF-7 Temporal profiling Metabolic adaption Dysregulation correlation

HTML PDF 收藏

Green building research from design to operation in the past 20 years: A perspective

Borong LIN, Yi WANG, Jiaping LIU, Juan YU

《结构与土木工程前沿（英文）》 2020年第14卷第5期页码 1049-1055 doi: 10.1007/s11709-020-0668-6

HTML PDF 收藏

Nicotinic acetylcholine receptor α7 subunit: a novel therapeutic target for cardiovascular diseases

null

《医学前沿（英文）》 2012年第6卷第1期页码 35-40 doi: 10.1007/s11684-012-0171-0

摘要：

Inflammation is important in the pathogenesis and development of cardiovascular diseases. Recent studies show that vagus nerve stimulation inhibits pro-inflammatory cytokine production through “the cholinergic anti-inflammatory pathway,” more specifically via the α7 nicotinic acetylcholine receptor (α7nAChR). In the current study, the role of the cholinergic anti-inflammatory pathway during septic shock, hypertension, and myocardial infarction is reviewed, and its possible clinical implications in cardiovascular diseases are discussed.

关键词： α7 nicotinic acetylcholine receptor cardiovascular diseases baroreflex sensitivity

HTML PDF 收藏

大秦线开行20 kt级重载组合列车系统集成与创新

耿志修

《中国工程科学》 2008年第10卷第3期页码 31-43

摘要：技术的结合，800 MHz数据电台与Locotrol技术的结合，单套Locotrol系统与SS4机车的结合，以及2台和谐型大功率机车加可控列尾的创新方式，开发了重载配套装备，通过集成创新，使大秦线开行20

关键词：中国铁路大秦线 20 kt级重载组合列车集成创新

HTML PDF 收藏

Research progress on human infection with avian influenza H7N9

Xiaoxin Wu, Lanlan Xiao, Lanjuan Li

《医学前沿（英文）》 2020年第14卷第1期页码 8-20 doi: 10.1007/s11684-020-0739-z

摘要： Since the first case of novel H7N9 infection was reported, China has experienced five epidemics of H7N9. During the fifth wave, a highly pathogenic H7N9 strain emerged. Meanwhile, the H7N9 virus continues to accumulate mutations, and its affinity for the human respiratory epithelial sialic acid 2-6 receptor has increased. Therefore, a pandemic is still possible. In the past 6 years, we have accumulated rich experience in dealing with H7N9, especially in terms of virus tracing, epidemiological research, key site mutation monitoring, critical disease mechanisms, clinical treatment, and vaccine development. In the research fields above, significant progress has been made to effectively control the spread of the epidemic and reduce the fatality rate. To fully document the research progress concerning H7N9, we reviewed the clinical and epidemiological characteristics of H7N9, the key gene mutations of the virus, and H7N9 vaccine, thus providing a scientific basis for further monitoring and prevention of H7N9 influenza epidemics.

关键词： H7N9 pandemic epidemiology mutations vaccine influenza

HTML PDF 收藏

Alteration of heat shock protein 20 expression in preeclamptic patients and its effect in vascular and

Fanfan Li, Mengzhou He, Meitao Yang, Yao Fan, Yun Chen, Xi Xia, Yin Xie, Dongrui Deng

《医学前沿（英文）》 2018年第12卷第5期页码 542-549 doi: 10.1007/s11684-017-0576-x

摘要：

Preeclampsia (PE) is a pregnancy-specific, multi-system disorder and the leading cause of maternal and perinatal morbidity and mortality in obstetrics worldwide. Excessive vasoconstriction and dysregulated coagulation function are closely associated with PE. Heat shock protein 20 (HSP20) is ubiquitously expressed under normal physiological conditions and has important roles in vascular dilatation and suppression of platelet aggregation. However, the role of HSP20 in the pathogenesis of PE remains unclear. In this study, we collected chorionic plate resistance arteries (CPAs) and serum from 118 healthy pregnant women and 80 women with PE and detected the levels of HSP20 and its phosphorylated form. Both HSP20 and phosphorylated HSP20 were downregulated in CPAs from women with PE. Comparison of the vasodilative ability of CPAs from the two groups showed impaired relaxation responses to acetyl choline in preeclamptic vessels. In addition to the reduced HSP20 in serum from women with PE, the platelet distribution width and mean platelet volume were also decreased, and the activated partial thromboplastin time and thromboplastin time were elevated. With regard to the vital roles of HSP20 in mediating vasorelaxation and coagulation function, the decreased HSP20 might contribute to the pathogenesis of PE.

关键词： preeclampsia heat shock protein 20 vascular relaxation coagulation-fibrinolytic system