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Research and Development of CAD/CAPP/CAM Integrated System
Wei Erwei,Liang Muyang,Yang Ping
Strategic Study of CAE 2000, Volume 2, Issue 4, Pages 59-63
In this paper a practical CAD/CAPP/CAM integrated system is introduced.developed by mechanical designers, process planners and NC progragmmers on the basis of a commercial CAD
Keywords: CAD CAPP CAM feature recognition
Shengwen ZHANG, Guicheng WANG, Liang ZHANG, Xifeng FANG
Frontiers of Mechanical Engineering 2009, Volume 4, Issue 1, Pages 97-102 doi: 10.1007/s11465-009-0007-z
Keywords: NC programming CAD/CAPP/CAM KBE
System Simulation for Large-scale Bridge Construction Schedule Based on 4D CAD
Zhang Zhengfeng,Fu Jinqiang,Wu Kangxin,Zhang Fayu
Strategic Study of CAE 2006, Volume 8, Issue 1, Pages 63-66
Keywords: construction schedule system simulation 4D CAD cable-stayed bridge
A Novel Attribute-Based Encryption Approach with Integrity Verification for CAD Assembly Models Article
Yueting Yang, Fazhi He, Soonhung Han, Yaqian Liang, Yuan Cheng
Engineering 2021, Volume 7, Issue 6, Pages 787-797 doi: 10.1016/j.eng.2021.03.011
Keywords: Information security Cloud-based design and manufacture Co-design CAD assembly models Attribute-based
Optimal localization of complex surfaces in CAD-based inspection
XU Jinting, LIU Weijun, SUN Yuwen
Frontiers of Mechanical Engineering 2008, Volume 3, Issue 4, Pages 426-433 doi: 10.1007/s11465-008-0068-4
Keywords: deviation comparison non-linear localization inspection
Study of Conceptual Design of Extension for Mechanical Products
Zhao Yanwei
Strategic Study of CAE 2001, Volume 3, Issue 5, Pages 67-71
Keywords: conceptual design mechanical product intelligent CAD extension
Ghulam ZAKRIA, Zailin GUAN, Yasser RIAZ, Mirza JAHANZAIB, Anwar KHAN,
Frontiers of Mechanical Engineering 2010, Volume 5, Issue 2, Pages 157-164 doi: 10.1007/s11465-010-0017-x
Keywords: computer-aided design (CAD) computer-aided manufacturing(CAM) SMEs analytical hierarchal approach Expert
Yingjun Wang,Mi Xiao,Zhaohui Xia,Peigen Li,Liang Gao
Engineering 2023, Volume 22, Issue 3, Pages 94-105 doi: 10.1016/j.eng.2022.07.013
Keywords: Human-aided design CAD/CAE integration Isogeometric analysis Structural optimization Isogeometric topology
An intersection algorithm based on transformation
CHEN Xiao-xia, YONG Jun-hai, CHEN Yu-jian
Frontiers of Mechanical Engineering 2006, Volume 1, Issue 3, Pages 364-369 doi: 10.1007/s11465-006-0024-0
Keywords: intersection superposi animation fundamental CAD/CAM
Research of Knowledge Database in Computer Aided Equipment Design System Based on I-deas
Yin Xiaowei,Hao Yongping,Qian Wenxue,Wei Yonghe
Strategic Study of CAE 2004, Volume 6, Issue 10, Pages 71-74
The frame, function and achievement method of knowledge sub-database in computer aided equipment design system based on I-deas are introduced according to the principle of Knowledge Based Engineering. The relations among the sub-databases are analyzed. Finally, the integration of the knowledge database and equipment design and management system is described in the computer aided equipment design system based on I-deas.
Keywords: equipment knowledge based engineering knowledge database of equipment group technology I-deas
Learning-based parameter prediction for quality control in three-dimensional medical image compression Research Articles
Yuxuan Hou, Zhong Ren, Yubo Tao, Wei Chen,3140104190@zju.edu.cn,renzhong@cad.zju.edu.cn
Frontiers of Information Technology & Electronic Engineering 2021, Volume 22, Issue 9, Pages 1169-1178 doi: 10.1631/FITEE.2000234
Keywords: 医学图像压缩;高效视频编码(HEVC);质量控制;基于学习方法
A Novel Human Antibody, HF, against HER2/erb-B2 Obtained by a Computer-Aided Antibody Design Method Article
Chunxia Qiao, Ming Lv, Xinying Li, Xiaoling Lang, Shouqin Lv, Mian Long, Yan Li, Shusheng Geng, Zhou Lin, Beifen Shen , Jiannan Feng
Engineering 2021, Volume 7, Issue 11, Pages 1566-1576 doi: 10.1016/j.eng.2020.10.024
Fully human antibodies have minimal immunogenicity and safety profiles. At present, most potential antibody drugs in clinical trials are humanized or fully human. Human antibodies are mostly generated using the phage display method (in vitro) or by transgenic mice (in vivo); other methods include B lymphocyte immortalization, human–human hybridoma, and single-cell polymerase chain reaction. Here, we describe a structure-based computer-aided de novo design technology for human antibody generation. Based on the complex structure of human epidermal growth factor receptor 2 (HER2)/Herceptin, we first designed six short peptides targeting the potential epitope of HER2 recognized by Herceptin. Next, these peptides were set as complementarity determining regions in a suitable immunoglobulin frame, giving birth to a novel anti-HER2 antibody named “HF,” which possessed higher affinity and more effective anti-tumor activity than Herceptin. Our work offers a useful tool for the quick design and selection of novel human antibodies for basic mechanical research as well as for imaging and clinical applications in immune-related diseases, such as cancer and infectious diseases.
Keywords: HER2/erb-B2 Human antibody Computer-aided design
Title Author Date Type Operation
Research and Development of CAD/CAPP/CAM Integrated System
Wei Erwei,Liang Muyang,Yang Ping
Journal Article
CNC programming system for complex components based on KBE within integrated environment of CAD/CAPP/
Shengwen ZHANG, Guicheng WANG, Liang ZHANG, Xifeng FANG
Journal Article
System Simulation for Large-scale Bridge Construction Schedule Based on 4D CAD
Zhang Zhengfeng,Fu Jinqiang,Wu Kangxin,Zhang Fayu
Journal Article
A Novel Attribute-Based Encryption Approach with Integrity Verification for CAD Assembly Models
Yueting Yang, Fazhi He, Soonhung Han, Yaqian Liang, Yuan Cheng
Journal Article
Optimal localization of complex surfaces in CAD-based inspection
XU Jinting, LIU Weijun, SUN Yuwen
Journal Article
Selecting and prioritizing key factors for CAD/CAM software in small- and medium-sized enterprises using
Ghulam ZAKRIA, Zailin GUAN, Yasser RIAZ, Mirza JAHANZAIB, Anwar KHAN,
Journal Article
From Computer-Aided Design (CAD) Toward Human-Aided Design (HAD): An Isogeometric Topology Optimization
Yingjun Wang,Mi Xiao,Zhaohui Xia,Peigen Li,Liang Gao
Journal Article
An intersection algorithm based on transformation
CHEN Xiao-xia, YONG Jun-hai, CHEN Yu-jian
Journal Article
Research of Knowledge Database in Computer Aided Equipment Design System Based on I-deas
Yin Xiaowei,Hao Yongping,Qian Wenxue,Wei Yonghe
Journal Article
Learning-based parameter prediction for quality control in three-dimensional medical image compression
Yuxuan Hou, Zhong Ren, Yubo Tao, Wei Chen,3140104190@zju.edu.cn,renzhong@cad.zju.edu.cn
Journal Article
Wang Yingjun: From Computer-aided Design (CAD) to Human Aided Design (HAD): An Isogeometric Topology
13 Jun 2023
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