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FBRM and PVM investigations of the double feed semi-batch crystallization of 6-aminopenicillanic acid

Min SU, Lin WANG, Hua SUN, Jingkang WANG

Frontiers of Chemical Science and Engineering 2009, Volume 3, Issue 3, Pages 282-288 doi: 10.1007/s11705-009-0018-7

Abstract: The focused beam reflectance measurement (FBRM) technology and particle vision measurement (PVM) technologyRecords and analysis of FBRM indicated that the nucleation of double feeding policy was much higher than

Keywords： 6-aminopenicillanic acid crystallization double-feeding FBRM PVM crystal habit

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Precipitation study of CO

Siming Chen, Yue Wu, Geoffrey W. Stevens, Guoping Hu, Wenshou Sun, Kathryn A. Mumford

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 3, Pages 415-424 doi: 10.1007/s11705-019-1882-4

Abstract: Focused beam reflectance measurement (FBRM) and C nuclear magnetic resonance ( C NMR) analysis wereThe FBRM results showed that the number of particles formed increased with CO loading and ethanol addition

Keywords： crystallization precipitation glycinate FBRM ¹³C NMR