Resource Type

Journal Article 4

Year

2022 1

2017 1

2009 1

Keywords

2-Hydroxybutyric acid 1

Astragalus 1

Chitosan 1

Extracellular polymeric substance 1

Functional metabolomics 1

Hydrogels 1

Intestine-targeted 1

Intrinsic viscosity 1

Membrane bioreactor 1

Membrane fouling 1

Molecular weight 1

Obesity 1

Oral delivery 1

Polysaccharides 1

Soluble microbial product 1

attainable information 1

biopolymer 1

capable 1

development 1

literature 1

open ︾

Search scope:

排序： Display mode:

Advancements in non-starch polysaccharides research for frozen foods and microencapsulation of probiotics

Pavan Kumar SOMA, Patrick D. WILLIAMS, Y. Martin LO,

Frontiers of Chemical Science and Engineering 2009, Volume 3, Issue 4,   Pages 413-426 doi: 10.1007/s11705-009-0254-x

Abstract: food industry as stabilizing, thickening, gelling, and suspending or dispersing agents, non-starch polysaccharidesIn the wake of growing interest in finding ideal encapsulating agents for probiotics, non-starch polysaccharidesthere remains a void in the literature in terms of closely comparing the characteristics of non-starch polysaccharidesTherefore, it is this review’s intention to focus on the selection criteria of non-starch polysaccharides

Keywords： development     literature     attainable information     biopolymer     capable    

HTML PDF Collect

exclusion chromatography characterization of molecular and solution properties of soluble microbial polysaccharides

Qingbin Guo,Sheng Chang

Frontiers of Environmental Science & Engineering 2017, Volume 11, Issue 2, doi: 10.1007/s11783-017-0922-x

Abstract: In this study, the distributions of the absolute molecular weight and intrinsic viscosity of SMP polysaccharidesabsolute molecular weights and intrinsic viscosity, a universal calibration relationship for the SMP polysaccharidesdeveloped and the molecular conformations, average molecular weights, and hydrodynamic sizes of the SMP polysaccharidesanalysis were proposed for the characterization of the viscous and osmotic pressure properties of the SMP polysaccharides

Keywords： Soluble microbial product     Extracellular polymeric substance     Membrane bioreactor     Membrane fouling     Molecular weight     Intrinsic viscosity    

HTML PDF Collect

Functional Metabolomics Reveals that Astragalus Polysaccharides Improve Lipids Metabolism through Article

Bingbing Li, Ying Hong, Yu Gu, Shengjie Ye, Kaili Hu, Jian Yao, Kan Ding, Aihua Zhao, Wei Jia, Houkai Li

Engineering 2022, Volume 9, Issue 2,   Pages 111-122 doi: 10.1016/j.eng.2020.05.023

Abstract:

Polysaccharides are widely present in herbs with multiple activities, especially immunity regulationThis study explores the mechanisms underlying the metabolic benefits of Astragalus polysaccharidesmetabolomics is practical for investigating the mechanism underlying the systemic benefits of plant polysaccharides

Keywords： Astragalus     polysaccharides (APS)     Functional metabolomics     2-Hydroxybutyric acid     Obesity    

HTML PDF Collect

A Double-Layer Polysaccharide Hydrogel (DPH) for the Enhanced Intestine-Targeted Oral Delivery of Probiotics

Wen-Can Huang,Wenjie Wang,Wei Wang,Yanan Hao,Changhu Xue,Xiangzhao Mao,

Engineering doi: 10.1016/j.eng.2023.05.024

Abstract: Transplantation of probiotics to the intestine can positively regulate the gut microbiota, thereby promoting the immune system and treating various diseases. However, the harsh gastrointestinal environment and short retention time in the gastrointestinal tract significantly limit the bioavailability and intestinal colonization of probiotics. Herein, we present a double-layer polysaccharide hydrogel (DPH) in the form of a double-layer structure composed of a carboxymethyl cellulose (CMCL) supramolecular inner layer and a dialdehyde alginate (DAA) cross-linked carboxymethyl chitosan (CMCS) outer layer. This double-layer structure allows DPH to encapsulate and deliver probiotics in a targeted manner within the body. In the stomach, the cage structure of the DPH is closed, and the outer layer absorbs surrounding liquids to form a barrier to protect the probiotics from gastric fluids. In the intestine, the cage structure opens and disintegrates, releasing the probiotics. Thus, DPH endows probiotics with excellent intestine-targeted delivery, improved oral bioavailability, enhanced gastrointestinal tract tolerance, and robust mucoadhesion capacity. The encapsulated probiotics exhibit almost unchanged bioactivity in the gastrointestinal tract before release, as well as improved oral delivery. In particular, probiotics encapsulated by DPH exhibit 100.1 times higher bioavailability and 10.6 times higher mucoadhesion than free probiotics in an animal model 48 h post-treatment. In addition, with a remarkable ability to survive and be retained in the intestine, probiotics encapsulated by DPH show excellent in vitro and in vivo competition with pathogens. Notably, DAA-mediated dynamic crosslinking not only maintains the overall integrity of the hydrogels but also controls the release timing of the probiotics. Thus, it is expected that encapsulated substances (probiotics, proteins, etc.) can be delivered to specific sites of the intestinal tract by means of DPH, by controlling the dynamic covalent crosslinking.

Keywords： Polysaccharides     Chitosan     Hydrogels     Oral delivery     Intestine-targeted    

HTML PDF Collect

Title Author Date Type Operation

Advancements in non-starch polysaccharides research for frozen foods and microencapsulation of probiotics

Pavan Kumar SOMA, Patrick D. WILLIAMS, Y. Martin LO,

Journal Article

exclusion chromatography characterization of molecular and solution properties of soluble microbial polysaccharides

Qingbin Guo,Sheng Chang

Journal Article

Functional Metabolomics Reveals that Astragalus Polysaccharides Improve Lipids Metabolism through

Bingbing Li, Ying Hong, Yu Gu, Shengjie Ye, Kaili Hu, Jian Yao, Kan Ding, Aihua Zhao, Wei Jia, Houkai Li

Journal Article

A Double-Layer Polysaccharide Hydrogel (DPH) for the Enhanced Intestine-Targeted Oral Delivery of Probiotics

Wen-Can Huang,Wenjie Wang,Wei Wang,Yanan Hao,Changhu Xue,Xiangzhao Mao,

Journal Article