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Monocyte subsets and their differentiation tendency after burn injury

Guangqing Wang, Zhaofan Xia

Frontiers of Medicine 2013, Volume 7, Issue 4,   Pages 397-400 doi: 10.1007/s11684-013-0298-7

Abstract:

Monocytes are critical effectors and regulators of immune response. Studying the nomenclature of monocyte subsets may be beneficial for understanding the complex function of monocytes in steady and inflammatory states. A monocyte has the potential to differentiate into dendritic cells or macrophages, and this behavior significantly changes in severely burned patients and mice. The findings in the present study may help enhance understanding on the perturbation of the immune system after severe burn injury.

Keywords： monocyte     differentiation     burn    

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GID complex regulates the differentiation of neural stem cells by destabilizing TET2

Frontiers of Medicine doi: 10.1007/s11684-023-1007-9

Abstract: Brain development requires a delicate balance between self-renewal and differentiation in neural stemYet, the regulation of TET2 in the process of neuronal differentiation remains unknown.Here, the protein level of TET2 was reduced by the ubiquitin-proteasome pathway during NSC differentiationThe protein levels of GID complex subunits increased reciprocally with TET2 level upon NSC differentiationillustrated that the GID complex negatively regulates TET2 protein stability, further modulates NSC differentiation

Keywords： TET2     GID complex     neural stem cells     differentiation of neurons    

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Abivertinib inhibits megakaryocyte differentiation and platelet biogenesis

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 416-428 doi: 10.1007/s11684-021-0838-5

Abstract: in the progression of megakaryopoiesis, we speculate that abivertinib can affect megakaryocyte (MK) differentiationwith abivertinib and observed megakaryopoiesis to determine the biological effect of abivertinib on MK differentiationimpaired the CFU-MK formation, proliferation of CD34+ HSC-derived MK progenitor cells, and differentiationand functions of MKs and inhibited Meg-01-derived MK differentiation.Thus, these preclinical data collectively suggested that abivertinib could inhibit MK differentiation

Keywords： abivertinib     Btk inhibitor     platelet     megakaryocyte     megakaryopoiesis     thrombopoiesis    

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The secondary laticifer differentiation in rubber tree is induced by trichostatin A, an inhibitor of

Shixin ZHANG,Shaohua WU,Weimin TIAN

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 4,   Pages 357-362 doi: 10.15302/J-FASE-2016125

Abstract: Although jasmonates have been demonstrated to be crucial in the regulation of secondary laticifer differentiation, the mechanism for the jasmonate-induced secondary laticifer differentiation remains to be elucidatedthat trichostatin A (TSA), an inhibitor of histone deacetylation, could induce the secondary laticifer differentiationThe results suggest that histone acetylation is essential for the secondary laticifer differentiation

Keywords： Hevea brasiliensis     histone acetylation     laticifer differentiation     trichostatin     vascular cambia    

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Tank-dependence of the functionality and network differentiation of activated sludge community in a full-scale

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 3, doi: 10.1007/s11783-023-1636-x

Abstract:

● Environmental parameters affected functional bacteria and network associations.

Keywords： Activated sludge     Bacterial community     Tank-dependence     Network association     Functional bacteria    

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coupling relationship of industrial agglomeration and low-carbon economy considering spatiotemporal differentiation

Frontiers of Engineering Management 2023, Volume 10, Issue 2,   Pages 285-299 doi: 10.1007/s42524-022-0197-1

Abstract: Although China’s construction machinery thrives to meet the needs of construction, a number of challenges still remain to be overcome, such as lack of thorough knowledge of regional disparities and several limitations in terms of carbon emissions and economic development. Meanwhile, a low-carbon economy was proposed and implemented in China. This research aims to investigate the differences in industrial agglomeration of construction machineries and further explore the relationship between industrial agglomeration and low-carbon economy. On this basis, spatiotemporal analysis was performed to evaluate the levels of industrial agglomeration in different regions based on the situations of China’s construction machinery industry. Furthermore, this study explored the interaction between industrial agglomeration and low-carbon economy utilizing the coupling coordination analysis method. Results showed that the coupling coordination of the two subsystems was extremely unbalanced in 2006, and it maintained an increasing trend, reaching a relatively high level in 2018. Finally, suggestions, such as establishing a policy guarantee system and implementing variable policies in different regions, were proposed to provide guidelines for the government decision-making and promote the sustainable development of China’s construction machinery industry.

Keywords： spatiotemporal differentiation     industrial agglomeration     low-carbon economy     construction machinery    

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Repression of CDKN2C caused by PML/RARα binding promotes the proliferation and differentiation block

Xiaoling Wang,Yun Tan,Yizhen Li,Jingming Li,Wen Jin,Kankan Wang

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 420-429 doi: 10.1007/s11684-016-0478-3

Abstract: expression of CDKN2C induced a cell cycle arrest at the G0/G1 phase and a partial differentiationthis study highlights the importance of CDKN2C inactivation in the abnormal cell cycle progression and differentiation

Keywords： CDKN2C     acute promyelocytic leukemia     cell cycle arrest     differentiation    

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Cannabidiol prevents depressive-like behaviors through the modulation of neural stem cell differentiation

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 227-239 doi: 10.1007/s11684-021-0896-8

Abstract: Chronic stress impairs radial neural stem cell (rNSC) differentiation and adult hippocampal neurogenesisTherefore, investigating the mechanism of neural differentiation and AHN is of great importance for developingHowever, whether CBD can modulate rNSC differentiation and hippocampal neurogenesis is unknown.administration of CBD rescued depressive-like symptoms in CRS mice and prevented rNSCs overactivation and differentiationThese results revealed a previously unknown neural mechanism for neural differentiation and AHN in depression

Keywords： cannabidiol     depression     radial neural stem cells     neurogenesis    

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Industrial eco-efficiency and its spatial-temporal differentiation in China

Wei YANG, Fengjun JIN, Chengjin WANG, Chen LV

Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 4,   Pages 559-568 doi: 10.1007/s11783-012-0400-4

Abstract: The aim of this paper is to study the spatial-temporal differentiation of industrial eco-efficiency in

Keywords： industrial eco-efficiency     data envelopment analysis (DEA) model     exploratory spatial data analysis (ESDA)    

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Syndrome Differentiation for AIDS

Wang Wenkui,Wang Feng,Wang Ling

Strategic Study of CAE 2007, Volume 9, Issue 8,   Pages 30-34

Abstract:

According to modern medicine, AIDS is a kind of acute acquired immune deficiency syndrome. This happens to hold an identical view with"essential qi" in traditional Chinese medicine. "Qi" relies on vigour, and vigour is based on the scent and the essence of food. The transformation of the essential substance depends on the performance of zangfu functions. The functional actions of zangfu organs are the foundation of life. For the five zang orans, each has something to dominate and each performs its own functions. They are interdependent with each other and in harmonv with each other. Only when the five zang organs are in vigorous state and in harmony with each other, can the life-force of body be full of vital power and the body be full of "essential qi" . Amid the five zang organs, as long as the functions of liver, spleen and kidney remain in harmony, heart and lung will naturally be in the harmonious state, hence a healthy body and extended life expectancy can be achieved, That is the rule of "keeping relative balance of three internal systems" (or "three-dynamic balancing method" ).

Keywords： AIDS     syndrome differentiation     five zang function     keeping relative balance of three internal systems    

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Resveratrol promotes the survival and neuronal differentiation of hypoxia-conditioned neuronal progenitor

Yao Yao, Rui Zhou, Rui Bai, Jing Wang, Mengjiao Tu, Jingjing Shi, Xiao He, Jinyun Zhou, Liu Feng, Yuanxue Gao, Fahuan Song, Feng Lan, Xingguo Liu, Mei Tian, Hong Zhang

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 472-485 doi: 10.1007/s11684-021-0832-y

Abstract: transplanted neuronal progenitor cells (NPCs) in rats with cerebral ischemia but could also hinder neuronal differentiationResveratrol was first applied during the neuronal differentiation of hcNPCs and concurrently promotedthe differentiation, synaptogenesis, and functional development of neurons derived from hcNPCs and restoredResveratrol promoted neuronal differentiation and increased the long-term survival of transplanted hcNPCsIn conclusion, resveratrol promoted the neuronal differentiation and therapeutic efficiency of hcNPCs

Keywords： neuronal progenitor cells     resveratrol     cerebral ischemia     neuronal differentiation     mitochondrial metabolism    

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Stem cell research in hepatocellular carcinoma

SUN Chengyi, ZUO Shi

Frontiers of Medicine 2008, Volume 2, Issue 1,   Pages 1-4 doi: 10.1007/s11684-008-0001-6

Abstract: However, whether HCC is resulted from the differentiation block of stem cells and, moreover, which liver

Keywords： lineage     hepato-pancreas     differentiation block     carcinogenesis     current status    

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The role of microRNAs in adipocyte differentiation

Rong Zhang, Di Wang, Zhuying Xia, Chao Chen, Peng Cheng, Hui Xie, Xianghang Luo

Frontiers of Medicine 2013, Volume 7, Issue 2,   Pages 223-230 doi: 10.1007/s11684-013-0252-8

Abstract: In this review, we summarize the biology and functional mechanisms of miRNAs in adipocyte differentiation

Keywords： microRNA     adipocyte     differentiation     adipogenesis    

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Developmental expression of CAPON and Dexras1 in spinal cord of rats

LI Xin, CHENG Chun, CHEN Mengling, GAO Shangfeng, ZHAO Jian, NIU Shuqiong, SHEN Aiguo

Frontiers of Medicine 2008, Volume 2, Issue 1,   Pages 75-81 doi: 10.1007/s11684-008-0014-1

Abstract: during development process of rat indicates that the adaptor protein, CAPON may play a probable role in differentiation

Keywords： CAPON     ISH     differentiation     postnatal     different subcellular    

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MicroRNAs and their roles in osteoclast differentiation

Zhuying Xia, Chao Chen, Peng Chen, Hui Xie, Xianghang Luo

Frontiers of Medicine 2011, Volume 5, Issue 4,   Pages 414-419 doi: 10.1007/s11684-011-0168-0

Abstract: Although various miRNAs regulate cell proliferation and differentiation, few miRNAs have been reportedto play a key role in the regulation of osteoclast differentiation.

Keywords： miRNA     osteoclast differentiation     antagomirs    

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Title Author Date Type Operation

Monocyte subsets and their differentiation tendency after burn injury

Guangqing Wang, Zhaofan Xia

Journal Article

GID complex regulates the differentiation of neural stem cells by destabilizing TET2

Journal Article

Abivertinib inhibits megakaryocyte differentiation and platelet biogenesis

Journal Article

The secondary laticifer differentiation in rubber tree is induced by trichostatin A, an inhibitor of

Shixin ZHANG,Shaohua WU,Weimin TIAN

Journal Article

Tank-dependence of the functionality and network differentiation of activated sludge community in a full-scale

Journal Article

coupling relationship of industrial agglomeration and low-carbon economy considering spatiotemporal differentiation

Journal Article

Repression of CDKN2C caused by PML/RARα binding promotes the proliferation and differentiation block

Xiaoling Wang,Yun Tan,Yizhen Li,Jingming Li,Wen Jin,Kankan Wang

Journal Article

Cannabidiol prevents depressive-like behaviors through the modulation of neural stem cell differentiation

Journal Article

Industrial eco-efficiency and its spatial-temporal differentiation in China

Wei YANG, Fengjun JIN, Chengjin WANG, Chen LV

Journal Article

Syndrome Differentiation for AIDS

Wang Wenkui,Wang Feng,Wang Ling

Journal Article

Resveratrol promotes the survival and neuronal differentiation of hypoxia-conditioned neuronal progenitor

Yao Yao, Rui Zhou, Rui Bai, Jing Wang, Mengjiao Tu, Jingjing Shi, Xiao He, Jinyun Zhou, Liu Feng, Yuanxue Gao, Fahuan Song, Feng Lan, Xingguo Liu, Mei Tian, Hong Zhang

Journal Article

Stem cell research in hepatocellular carcinoma

SUN Chengyi, ZUO Shi

Journal Article

The role of microRNAs in adipocyte differentiation

Rong Zhang, Di Wang, Zhuying Xia, Chao Chen, Peng Cheng, Hui Xie, Xianghang Luo

Journal Article

Developmental expression of CAPON and Dexras1 in spinal cord of rats

LI Xin, CHENG Chun, CHEN Mengling, GAO Shangfeng, ZHAO Jian, NIU Shuqiong, SHEN Aiguo

Journal Article

MicroRNAs and their roles in osteoclast differentiation

Zhuying Xia, Chao Chen, Peng Chen, Hui Xie, Xianghang Luo

Journal Article