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Journal Article 6

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endoscopy 2

in-body medical device 2

ingestible medical device 2

medical robot 2

miniature actuator 2

wireless capsule endoscopy 2

Gastric endoscopy 1

Histological examination 1

Liver cirrhosis 1

Microbiome 1

Symptoms 1

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artificial intelligence 1

cellular resolution 1

confocal endoscopy 1

gastro-intestinal 1

gastrointestinal diseases 1

gastrointestinal haemorrhage 1

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Capsule endoscopy—A mechatronics perspective

Lin LIN, Mahdi RASOULI, Andy Prima KENCANA, Su Lim TAN, Kai Juan WONG, Khek Yu HO, Soo Jay PHEE

Frontiers of Mechanical Engineering 2011, Volume 6, Issue 1, Pages 33-39 doi: 10.1007/s11465-011-0203-5

Abstract: Wireless capsule endoscopy is one of such medical devices that has gained significant attention duringIt is envisaged that future wireless capsule endoscopies replace traditional endoscopy procedures by

Keywords： wireless capsule endoscopy ingestible medical device in-body medical device medical robot miniature actuator

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Artificial intelligence in gastroenterology: where are we heading?

Joseph JY Sung, Nicholas CH Poon

Frontiers of Medicine 2020, Volume 14, Issue 4, Pages 511-517 doi: 10.1007/s11684-020-0742-4

Abstract: diagnosis of gastrointestinal conditions relies a lot on image-based investigations and procedures (endoscopy

Keywords： artificial intelligence endoscopy robotics gastrointestinal diseases

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Endoscopic resection of a huge Brunner's gland adenoma

ZHANG Binbin, REN Xu, TANG Xiufen, CHI Yuxin, SHI Xuesong

Frontiers of Medicine 2008, Volume 2, Issue 4, Pages 414-418 doi: 10.1007/s11684-008-0080-4

Abstract: Upper gastro-intestinal (GI) endoscopy revealed a large pedunculated tumour on the superior part of the

Keywords： superior Histological examination endoscopy gastro-intestinal gastrointestinal haemorrhage

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A Confocal Endoscope for Cellular Imaging Article

Jiafu Wang,Min Yang,Li Yang,Yun Zhang,Jing Yuan,Qian Liu,Xiaohua Hou,Ling Fu

Engineering 2015, Volume 1, Issue 3, Pages 351-360 doi: 10.15302/J-ENG-2015081

Abstract:

Since its inception, endoscopy has aimed to establish an immediate diagnosis that is virtually consistentIn the past decade, confocal laser scanning microscopy has been brought into endoscopy, thus enabling

Keywords： cellular resolution confocal endoscopy optical biopsy

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Ingestible wireless capsules for enhanced diagnostic inspection of gastrointestinal tract

Mahdi RASOULI, Andy Prima KENCANA, Van An HUYNH, Eng Kiat TING, Joshua Chong Yue LAI, Kai Juan WONG, Su Lim TAN, Soo Jay PHEE

Frontiers of Mechanical Engineering 2011, Volume 6, Issue 1, Pages 40-44 doi: 10.1007/s11465-011-0204-4

Abstract:

Wireless capsule endoscopy has become a common procedure for diagnostic inspection of gastrointestinalThis method offers a less-invasive alternative to traditional endoscopy by eliminating uncomfortableprocedures of the traditional endoscopy.

Keywords： wireless capsule endoscopy ingestible medical device in-body medical device miniature actuator medical

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Characterization of the Gastric Mucosal Microbiota in Patients with Liver Cirrhosis and Its Associations with Gastrointestinal Symptoms Article

Yanfei Chen, Jing Guo, Chunlei Chen, Ding Shi, Daiqiong Fang, Feng Ji, Lanjuan Li

Engineering 2021, Volume 7, Issue 4, Pages 507-514 doi: 10.1016/j.eng.2020.04.014

Abstract:

Several studies have indicated that the oral and gut microbiota may exhibit differences in patients with cirrhosis. Less is known about the microbiota in the stomach, which is located between the oral cavity and the intestinal tract. In this study, the gastric mucosal microbiota of patients with liver cirrhosis and controls were analyzed with 16S ribosomal RNA (rRNA) pyrosequencing. Cirrhotic patients had significantly
lower Helicobacter pylori (H. pylori) infection rates, as confirmed by both the histological method and the pyrosequencing method. In H. pylori-negative subjects, gastric bacterial communities of healthy and cirrhosis cohorts were clustered into four clusters based on bacterial compositions: Cluster_1 and Cluster_2 (mostly cirrhosis), Cluster_3 (mostly healthy), and Cluster_4 (around half of each). Compositional and functional differences were observed among these different clusters. At the genus level, Cluster_1 and Cluster_2 showed enrichment of Neisseria and Streptococcus, respectively. Functionally, Cluster_2 was characterized as depleted of genetic information processing, as well as of modules related to glycan biosynthesis and metabolism. Patients in Cluster_2 had more severe gastrointestinal symptoms and a higher rate of previous endoscopic variceal ligation (EVL) therapy than patients in other clusters. Our findings suggest that the colonization of both H. pylori and non-H. pylori is influenced in liver cirrhosis. Although the H. pylori-negative gastric mucosal microbiota showed considerable heterogeneity, associations between specific gastric microbiota and clinical characteristics could be observed. Previous EVL therapy might lead to a distinct structure of the gastric mucosal microbiota, thus aggravating the gastrointestinal symptoms in H. pylori-negative cirrhotic patients.

Keywords： Microbiome Liver cirrhosis Symptoms Varices Gastric endoscopy