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Etiology of invasive candidosis agents in Russia: a multicenter epidemiological survey

N.V. Vasilyeva, E.R. Raush, M.V. Rudneva, T.S. Bogomolova, A.E. Taraskina, Yong Fang, Fengmin Zhang, N.N. Klimko

Frontiers of Medicine 2018, Volume 12, Issue 1, Pages 84-91 doi: 10.1007/s11684-017-0612-x

Abstract:

A multicenter prospective epidemiological survey on the etiologic agents of invasive candidosis was conducted in Russia in the period of 2012–2014. Samples were collected from 284 patients with invasive candidosis and Candida species isolated by culture. The species were identified by DNA sequencing and MALDI-TOF mass-spectrometry. A total of 322 isolates were recovered, in which 96% of Сandida species belonged to six major species, namely, C. albicans (43.2%), C. parapsilosis (20.2%), C. glabrata (11.5%), C. tropicalis (9.6%), C. krusei (6.2%), and C. guilliermondii (5.3%). Most Candida species were isolated from blood samples (83.23%). Notably, the prevalence rate of C. albicans reduced from 52.38% to 32.79% (2012 vs. 2014) (P=0.01) whereas that of non-C. albicans increased from 47.62% (2012) to 67.21% (2014) (P<0.01). Species distribution differed among geographical regions; specifically, the prevalence rate of C. albicans as an etiologic agent of invasive candidosis in Siberian Federal region was significantly higher than that in other Federal regions. Results indicated a shift from C. albicans to non-C. albicans. Therefore, a detailed investigation on the contributing factors and appropriate treatment of invasive candidosis is needed.

Keywords： prevalence &Scy andida species invasive candidosis nosocomial etiology MALDI-TOF mass-spectrometry

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Update on Mayer–Rokitansky–Küster–Hauser syndrome

Frontiers of Medicine 2022, Volume 16, Issue 6, Pages 859-872 doi: 10.1007/s11684-022-0969-3

Abstract: The etiology of MRKH syndrome remains unclear due to its intrinsic heterogeneity.

Keywords： MRKH (Mayer–Rokitansky–Küster–Hauser) syndrome etiology clinical characteristic diagnosis treatment

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Summarization of Acupotomology System

Zhu Hanzhang

Strategic Study of CAE 2006, Volume 8, Issue 7, Pages 1-15

Abstract: The four basic theories include the theory of closed operation, the etiology and pathology of chronicsoft issue injury, the new etiology of hyperosteogeny, the etiology of spinal area and the theory of

Keywords： acupotomology closed operation the etiology of spinal area the electrophysiological conducting system

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Novel Insight into the Etiology of Haff Disease by Mapping the N-Glycome with Orthogonal Mass Article

Si Liu, Yuanyuan Liu, Jiajing Lin, Bi-Feng Liu, Zhenyu He, Xiaomin Wu, Xin Liu

Engineering 2023, Volume 26, Issue 7, Pages 63-73 doi: 10.1016/j.eng.2022.09.012

Abstract: may lead to Haff disease (HD), which is considered to result from an unidentified toxin, although the etiologyreveals the association of differential IgG N-glycosylation with HD, providing new insight into the etiology

Keywords： Haff disease Serum Immunoglobulin G Glycosylation Disease pathogenesis