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Etiology of invasive candidosis agents in Russia: a multicenter epidemiological survey

N.V. Vasilyeva, E.R. Raush, M.V. Rudneva, T.S. Bogomolova, A.E. Taraskina, Yong Fang, Fengmin Zhang, N.N. Klimko

Frontiers of Medicine 2018, Volume 12, Issue 1, Pages 84-91 doi: 10.1007/s11684-017-0612-x

Abstract:

A multicenter prospective epidemiological survey on the etiologic agents of invasive candidosis was conducted in Russia in the period of 2012–2014. Samples were collected from 284 patients with invasive candidosis and Candida species isolated by culture. The species were identified by DNA sequencing and MALDI-TOF mass-spectrometry. A total of 322 isolates were recovered, in which 96% of Сandida species belonged to six major species, namely, C. albicans (43.2%), C. parapsilosis (20.2%), C. glabrata (11.5%), C. tropicalis (9.6%), C. krusei (6.2%), and C. guilliermondii (5.3%). Most Candida species were isolated from blood samples (83.23%). Notably, the prevalence rate of C. albicans reduced from 52.38% to 32.79% (2012 vs. 2014) (P=0.01) whereas that of non-C. albicans increased from 47.62% (2012) to 67.21% (2014) (P<0.01). Species distribution differed among geographical regions; specifically, the prevalence rate of C. albicans as an etiologic agent of invasive candidosis in Siberian Federal region was significantly higher than that in other Federal regions. Results indicated a shift from C. albicans to non-C. albicans. Therefore, a detailed investigation on the contributing factors and appropriate treatment of invasive candidosis is needed.

Keywords： prevalence &Scy andida species invasive candidosis nosocomial etiology MALDI-TOF mass-spectrometry

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A Blockchain-Based Life-Cycle Environmental Management Framework for Hospitals in the COVID-19 Context Article

Botao Zhong,Han Gao,Lieyun Ding,Yuhang Wang

Engineering 2023, Volume 20, Issue 1, Pages 208-221 doi: 10.1016/j.eng.2022.06.024

Abstract: Environmental management in the hospital life cycle is vital in preventing nosocomial infection and includesinvestigates how blockchain technology can transform the work quality inspection workflow to assist in nosocomial

Keywords： Blockchain Environmental management Nosocomial infection control Work quality management Life-cycle