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Jie Zheng,Yuzhen Gao,Yuejuan Jing,Xiaoshuang Zhou,Yuanyuan Shi,Yanhong Li,Lihua Wang,Ruiying Wang,Maolian Li,Chuanshi Xiao,Yafeng Li,Rongshan Li
Frontiers of Medicine 2014, Volume 8, Issue 4, Pages 477-483 doi: 10.1007/s11684-014-0346-y
Keywords： dyslipidemia plasma lipids plasma fasting glucose impaired fasting glucose non-diabetes
Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 7, doi: 10.1007/s11783-023-1686-0
● Lipid can promote PA production on a target from food waste.
Keywords： Acidogenic fermentation Microbial community Volatile fatty acid Propionate Food waste Lipid
Technologies for extracting lipids from oleaginous microorganisms for biodiesel production
Cunwen WANG, Lu CHEN, Bajpai RAKESH, Yuanhang QIN, Renliang LV
Frontiers in Energy 2012, Volume 6, Issue 3, Pages 266-274 doi: 10.1007/s11708-012-0193-y
Keywords： oleaginous microorganisms biodiesel solvent extraction ultrasound-assisted extraction microwave-assisted extraction supercritical fluid extraction (SFE)
Current Status of Blood Lipid Level and Prevention Strategy of Lipid Disorder in Chinese Population
Chen Haozhu,Jin Xuejuan
Strategic Study of CAE 2002, Volume 4, Issue 11, Pages 1-6
To assess current status of serum lipid levels in healthy inhabitants of China and their secular trend in the past 5 decades. Methods： The authors reviewed the contemporary literature (studies published between 1959 and 2002; bibliographies of reviews and original articles). Articles were included if they were following a standardized protocol for serum collection and lipid examination. Thirty-five articles in different target population from Beijin, Shanghai, Guangzhou, Tianjin and Kunming met inclusion criteria. This paper summarized important results of these studies and also the author´s own study performed in Shanghai on lipid epidemiology. Results： (1)The levels of blood total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and triglyceride (TG) increased along with the age. The levels of TC, TG and LDL-C among women before fifty were similar to that of among men of the same age, but higher in women than men over fifty. The TC, TG and LDL-C levels were higher in urban area than in rural area. (2) The levels of high density lipoprotein cholesterol (HDL-C) kept stability with aging, and they were lower in men than in women. (3)Secular trend analyses showed that the level of TC, TG and LDL-C increased steadily and significantly in all population, which reached the highest level at the end of 1990s, while HDL-C level decreased. (4) The prevalence of hypercholesterolemia (TC＞ 200 - 220 mg/dL) differed greatly among different population, from 17.8% to 54.9% in men, and from 14.9% to 53.4% in women, respectively. (5) Possible determinants for these changes were alternations in the composition of the diet in Chinese population along with the rise of living standards of the people. Daily intake of dietary fat, animal protein and cholesterol increased, while the proportion of carbohydrate decreased. (6) Coronary heart disease has been become the most common heart disease in China correlating with these changes. Prevention strategies： Primary prevention including： (1) resume healthy diet and have reasonable composition of the diet; (2) have lifestyle modifications and reduce other coronary heart disease risk; (3) recommendation for increasing physical activity. Secondary prevention including： If the patient did not achieve recommended target lipid levels after 3 months of lifestyle modifications (dietary therapy and physical activity), he or she should receive pharmacotherapy for dislipidemia.
Keywords： blood lipids epidemiology prevention
Effects of cultivation strategies on the cultivation of Chlorella sp. HQ in photoreactors
Xiaoya Liu, Yu Hong, Peirui Liu, Jingjing Zhan, Ran Yan
Frontiers of Environmental Science & Engineering 2019, Volume 13, Issue 5, doi: 10.1007/s11783-019-1162-z
Keywords： HQ Cultivation strategy lipids Nitrogen removal Phosphorus removal Reactive oxygen species
High Sn-2 Docosahexaenoic Acid Lipids for Brain Benefits, and Their Enzymatic Syntheses: A Review Review
Jun Jin, Qingzhe Jin, Xingguo Wang, Casimir C. Akoh
Engineering 2020, Volume 6, Issue 4, Pages 424-431 doi: 10.1016/j.eng.2020.02.009
Functional Metabolomics Reveals that Astragalus Polysaccharides Improve Lipids Metabolism through Article
Bingbing Li, Ying Hong, Yu Gu, Shengjie Ye, Kaili Hu, Jian Yao, Kan Ding, Aihua Zhao, Wei Jia, Houkai Li
Engineering 2022, Volume 9, Issue 2, Pages 111-122 doi: 10.1016/j.eng.2020.05.023
Polysaccharides are widely present in herbs with multiple activities, especially immunity regulation and metabolic benefits for metabolic disorders. However, the underlying mechanisms are not well understood. Functional metabolomics is increasingly used to investigate systemic effects on the host by identifying metabolites with particular functions. This study explores the mechanisms underlying the metabolic benefits of Astragalus polysaccharides (APS) by adopting a functional metabolomics strategy. The effects of APS were determined in eight-week high-fat diet (HFD)-fed obese mice. Then, gas chromatography–time-of-flight mass spectrometry (GC–TOFMS)-based untargeted metabolomics was performed for an analysis of serum and liver tissues, and liquid chromatography–tandem mass spectrometry (LC–MS/MS)-based targeted metabolomics was performed. The potential functions of the metabolites were tested with in vitro and in vivo models of metabolic disorders. Our results first confirmed the metabolic benefits of APS in obese mice. Then, metabolomics analysis revealed that APS supplementation reversed the HFD-induced metabolic changes, and identified 2-hydroxybutyric acid (2-HB) as a potential functional metabolite for APS activity that was significantly decreased by a HFD and reversed by APS. Further study indicated that 2-HB inhibited oleic acid (OA)-induced triglyceride (TG) accumulation. It was also found to stimulate the expression of proteins in lipid degradation in hepatocytes and TG lipolysis in 3T3-L1 cells. Moreover, it was found to reduce serum TG and regulate the proteins involved in lipid degradation in high-fat and high-sucrose (HFHS)-fed mice. In conclusion, our study demonstrates that the metabolic benefits of APS are at least partially due to 2-HB generation, which modulated lipid metabolism both in vitro and in vivo. Our results also highlight that functional metabolomics is practical for investigating the mechanism underlying the systemic benefits of plant polysaccharides.
Keywords： Astragalus polysaccharides (APS) Functional metabolomics 2-Hydroxybutyric acid Obesity
Title Author Date Type Operation
Gender differences in the relationship between plasma lipids and fasting plasma glucose in non-diabetic
Jie Zheng,Yuzhen Gao,Yuejuan Jing,Xiaoshuang Zhou,Yuanyuan Shi,Yanhong Li,Lihua Wang,Ruiying Wang,Maolian Li,Chuanshi Xiao,Yafeng Li,Rongshan Li
Journal Article
The role of lipids in fermentative propionate production from the co-fermentation of lipid and food waste
Journal Article
Technologies for extracting lipids from oleaginous microorganisms for biodiesel production
Cunwen WANG, Lu CHEN, Bajpai RAKESH, Yuanhang QIN, Renliang LV
Journal Article
Current Status of Blood Lipid Level and Prevention Strategy of Lipid Disorder in Chinese Population
Chen Haozhu,Jin Xuejuan
Journal Article
Effects of cultivation strategies on the cultivation of Chlorella sp. HQ in photoreactors
Xiaoya Liu, Yu Hong, Peirui Liu, Jingjing Zhan, Ran Yan
Journal Article
High Sn-2 Docosahexaenoic Acid Lipids for Brain Benefits, and Their Enzymatic Syntheses: A Review
Jun Jin, Qingzhe Jin, Xingguo Wang, Casimir C. Akoh
Journal Article
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