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Nicotine gum or patch treatment for smoking cessation and smoking reduction: a multi-centre study in

Dan Xiao, Nanshan Zhong, Chunxue Bai, Qingyu Xiu, Canmao Xie, Dayi Hu, Yun Mao, Roland Perfekt, Elisabeth Kruse, Qing Li, John Jiangnan Liu, Chen Wang

Frontiers of Medicine 2014, Volume 8, Issue 1, Pages 84-90 doi: 10.1007/s11684-014-0311-9

Abstract: gum and nicotine patch in Chinese healthcare professionals.All subjects were accepted nicotine replacement therapy, and they could choose nicotine gum (2 mg or4 mg, depending on baseline smoking level) or nicotine patch (15 mg/16 h) for 12 weeks, with a 12-weekNicotine patch and gum were well tolerated in Chinese smokers.Abstinence rates were comparable to those previously reported with nicotine replacement therapy, and

Keywords： nicotine replacement therapy smoking cessation Chinese physicians

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Effect of ambient polycyclic aromatic hydrocarbons and nicotine on the structure of Aβ protein

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 2, doi: 10.1007/s11783-023-1615-2

Abstract:

● B[a]P, nicotine and phenanthrene molecules altered the secondary

Keywords： Polycyclic aromatic hydrocarbons Nicotine toxicology Aβ₄₂ peptide Alzheimer’s disease

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Protective effects of nicotine on gamma-aminobutyric acid neurons and dopaminergic neurons in mice with

Lei FU MD , Dezheng GONG BM , Yan PENG , Dongmei WANG BM , Hong XU , Yue LI MD , Dengqin YU BS , Yanhui FENG MD , Shengming YIN PhD , Jin GONG , Yiping SUN PhD ,

Frontiers of Medicine 2009, Volume 3, Issue 3, Pages 330-335 doi: 10.1007/s11684-009-0051-4

Abstract: This study aimed to investigate the protective effect of nicotine on dopaminergic neurons and its mechanismsNicotine was given for 10 days in the nicotine therapeutic group.The results showed that pretreatment with nicotine could improve the dyskinesia of PD mice markedly.Simultaneously, TH-positive ( < 0.01) neurons and GABA-positive ( < 0.05) neurons in the nicotineThe ultrastructural injury of the nicotine therapeutic group was also ameliorated.

Keywords： Parkinson disease nicotine dopaminergic neuron gamma-aminobutyric acid neuron

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Effect of fly ash replacement level on the fracture behavior of concrete

Mahdi AREZOUMANDI, Jeffery S. VOLZ

Frontiers of Structural and Civil Engineering 2013, Volume 7, Issue 4, Pages 411-418 doi: 10.1007/s11709-013-0228-4

Abstract: This study presents the results of an experimental investigation that evaluates effect of fly ash replacementThis study includes four mixes with 0%, 30%, 50%, and 70% fly ash as a cement replacement.Results of these statistical tests show that the mix with higher level of fly ash replacement level has

Keywords： concrete fracture energy fly ash

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The evolution of surgical and medical treatment of aortic root aneurysm

Xu Yu Jin,Li Yuan,Mario Petrou,John R. Pepper

Frontiers of Medicine 2014, Volume 8, Issue 4, Pages 427-432 doi: 10.1007/s11684-014-0385-4

Abstract:

Since first report of aortic root replacement in 1968, the surgical risk and long term outcome ofTranslational research has also led to emerging surgical innovation and new drug therapy.

Keywords： aortic root aneurysm aortic root replacement valve sparing root replacement personalised external aortic

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term performance of recycled concrete beams with different water–cement ratio and recycled aggregate replacement

Jingwei YING; Feiming SU; Shuangren CHEN

Frontiers of Structural and Civil Engineering 2022, Volume 16, Issue 3, Pages 302-315 doi: 10.1007/s11709-022-0803-7

Abstract: performance of recycled aggregate concrete (RAC) components for different values of water−cement ratio and replacementGenerally, the concrete strength decreases with the increase of the replacement rate of RCA, in orderto meet the strength requirements when changing the replacement rate of RCA, it is necessary to changeproperties of reinforced concrete beams were tested respectively by changing water−cement ratio and RCA replacementThe brittleness of concrete before failure can be reduced more effectively by adjusting the replacement

Keywords： recycled concrete beam the replacement rate of recycled coarse aggregate water–cement ratio digital

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How to judge the association of postmenopausal hormone therapy and the risk of breast cancer

Ling XU

Frontiers of Medicine 2010, Volume 4, Issue 3, Pages 290-293 doi: 10.1007/s11684-010-0093-7

Abstract: The relevance of postmenopausal hormone therapy (HT) for breast cancer risk has been long debated, althoughThese unanswered questions include: whether HT has a positive impact on breast cancer; whether risks of therapy

Keywords： breast cancer postmenopausal hormone therapy unopposed estrogen therapy combined estrogen-progestin therapy

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Recycled glass replacement as fine aggregate in self-compacting concrete

Yasser SHARIFI, Mahmoud HOUSHIAR, Behnam AGHEBATI

Frontiers of Structural and Civil Engineering 2013, Volume 7, Issue 4, Pages 419-428 doi: 10.1007/s11709-013-0224-8

Abstract: as much as possible, the concrete industry has adopted a number of methods to achieve this goal by replacementTherefore, replacement of waste glass with fine aggregate in SCC should deeply be investigated comparedThe aim of the present study is to investigate the effect of glass replacement with fine aggregate onThe strength reduction of concrete in different glass replacement ratios is not remarkable, thus it can

Keywords： Self Compacting Concrete (SCC) recycle glass fine aggregate fresh and hardened properties

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Utilization of MSWI fly ash as partial cement or sand substitute with focus on cementing efficiency and health risk assessment

Lei Zheng, Xingbao Gao, Wei Wang, Zifu Li, Lingling Zhang, Shikun Cheng

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 1, doi: 10.1007/s11783-019-1184-6

Abstract: Sand replacing is beneficial for strength, while cement replacement reduces strength.highest strength (compressive strength= 30.2 Mpa; flexural strength= 7.0 Mpa) was obtained when the sand replacementThe k values of fly ash used for sand replacement were all significantly above that used for cement substitutionThe macropores assigned to the gaps between particles decreased when the fly ash was used as sand replacement

Keywords： MSWI fly ash Cementing efficiency Health risk assessment of heavy metal Sand replacement Cement replacement

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Particle therapy for cancers: a new weapon in radiation therapy

Guo-Liang Jiang

Frontiers of Medicine 2012, Volume 6, Issue 2, Pages 165-172 doi: 10.1007/s11684-012-0196-4

Abstract: and intensity-modulated radiation therapy, proton therapy has yielded more promising outcomes in localCarbon therapy in Japan showed even more promising results than proton therapy.The non-invasive nature of particle therapy affords more patients with chances to receive and benefitParticle therapy is gradually getting attention from the oncology community.However, the cost of particle therapy facilities has limited the worldwide use of this technology.

Keywords： radiation therapy particle therapy proton carbon cancer

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left ventricular remodelling and clinical outcome following surgical and trans-catheter aortic valve replacement

Frontiers of Medicine 2021, Volume 15, Issue 3, Pages 416-437 doi: 10.1007/s11684-021-0852-7

Abstract: Over the last half century, surgical aortic valve replacement (SAVR) has evolved to offer a durable andsystem for conduction abnormalities, further reduction in para-valvular aortic regurgitation along with therapy

Keywords： surgical aortic valve replacement trans-catheter aortic valve implantation left ventricular hypertrophy

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Targeted therapy of desmoid-type fibromatosis: mechanism, current situation, and future prospects

Zhen Wang, Jianhui Wu, Xiuyun Tian, Chunyi Hao

Frontiers of Medicine 2019, Volume 13, Issue 4, Pages 427-437 doi: 10.1007/s11684-018-0672-6

Abstract: Tyrosine kinase and γ-secretase inhibitors are primarily used in the targeted therapy of DF.Previous studies that focused on the mechanism, efficacy, and safety of targeted therapy for DF wereThe efficacy and safety of targeted therapy were compared with those of other systemic therapy optionsTargeted therapy does not provide considerable advantages in efficacy and safety over other medical treatmentsstudies are required to explore the mechanism, indications, and appropriate drug dosage of the targeted therapy

Keywords： targeted therapy desmoid-type fibromatosis tyrosine kinase inhibitor γ-secretase inhibitor

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mTOR-targeted cancer therapy: great target but disappointing clinical outcomes, why?

Shi-Yong Sun

Frontiers of Medicine 2021, Volume 15, Issue 2, Pages 221-231 doi: 10.1007/s11684-020-0812-7

Abstract: rationale, the intriguing question is why cancers are insensitive or not responsive to mTOR-targeted cancer therapyERK, and Mnk/eIF4E survival signaling pathways that compromise the efficacy of rapalog-based cancer therapyThese new findings may also offer us the opportunity to rationally utilize mTOR inhibitors in cancer therapy

Keywords： mTOR cancer therapy resistance GSK3 protein degradation E3 ubiquitin ligase PD-L1

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Determination Model for Replacement of Water Pipeline

Cui Hongsheng,Zhang Hongwei,Niu Zhiguang,Fu Yufen

Strategic Study of CAE 2007, Volume 9, Issue 9, Pages 68-71

Abstract:

A fund distribution model for water pipeline replacement at the levelconstruction fee, and decreasing the difference of pipeline maintenance fee before and after replacement

Keywords： water pipeline maintenance fee replacement fee fund distribution

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Silica-based nanoarchitecture for an optimal combination of photothermal and chemodynamic therapy functions

Frontiers of Chemical Science and Engineering doi: 10.1007/s11705-023-2362-4

Abstract: This study introduces multifunctional silica nanoparticles that exhibit both high photothermal and chemodynamic therapeutic activities, in addition to luminescence. The activity of the silica nanoparticles is derived from their plasmonic properties, which are a result of infusing the silica nanoparticles with multiple Cu_2–xS cores. This infusion process is facilitated by a recoating of the silica nanoparticles with a cationic surfactant. The key factors that enable the internal incorporation of the Cu_2–xS cores and the external deposition of red-emitting carbon dots are identified. The Cu_2–xS cores within the silica nanoparticles exhibit both self-boosting generation of reactive oxygen species and high photothermal conversion efficacy, which are essential for photothermal and chemodynamic activities. The silica nanoparticles’ small size (no more than 70 nm) and high colloidal stability are prerequisites for their cell internalization. The internalization of the red-emitting silica nanoparticles within cells is visualized using fluorescence microscopy techniques. The chemodynamic activity of the silica nanoparticles is associated with their dark cytotoxicity, and the mechanisms of cell death are evaluated using an apoptotic assay. The photothermal activity of the silica nanoparticles is demonstrated by significant cell death under near-infrared (1064 nm) irradiation.

Keywords： copper sulfide nanoparticles chemodynamic therapy photothermal therapy carbon dots silica nanoparticles

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Title Author Date Type Operation

Nicotine gum or patch treatment for smoking cessation and smoking reduction: a multi-centre study in

Dan Xiao, Nanshan Zhong, Chunxue Bai, Qingyu Xiu, Canmao Xie, Dayi Hu, Yun Mao, Roland Perfekt, Elisabeth Kruse, Qing Li, John Jiangnan Liu, Chen Wang

Journal Article

Effect of ambient polycyclic aromatic hydrocarbons and nicotine on the structure of Aβ protein

Journal Article

Protective effects of nicotine on gamma-aminobutyric acid neurons and dopaminergic neurons in mice with

Lei FU MD , Dezheng GONG BM , Yan PENG , Dongmei WANG BM , Hong XU , Yue LI MD , Dengqin YU BS , Yanhui FENG MD , Shengming YIN PhD , Jin GONG , Yiping SUN PhD ,

Journal Article

Effect of fly ash replacement level on the fracture behavior of concrete

Mahdi AREZOUMANDI, Jeffery S. VOLZ

Journal Article

The evolution of surgical and medical treatment of aortic root aneurysm

Xu Yu Jin,Li Yuan,Mario Petrou,John R. Pepper

Journal Article

term performance of recycled concrete beams with different water–cement ratio and recycled aggregate replacement

Jingwei YING; Feiming SU; Shuangren CHEN

Journal Article

How to judge the association of postmenopausal hormone therapy and the risk of breast cancer

Ling XU