Search | Engineering

Subscribe Submit

Home Journals Focus Achievement Fronts About Us 中文版

Resource Type

Journal Article 2

Year

2013 1

2010 1

Keywords

schizophrenia 2

antipsychotics 1

cytosolic phospholipase A2 1

epigenetics 1

ligase detection reaction 1

pharmacogenomics 1

polymorphism 1

open ︾

Search scope:

排序： Display mode:

Pharmacogenomics can improve antipsychotic treatment in schizophrenia

Qingqing Xu, Xi Wu, Yuyu Xiong, Qinghe Xing, Lin He, Shengying Qin

Frontiers of Medicine 2013, Volume 7, Issue 2, Pages 180-190 doi: 10.1007/s11684-013-0249-3

Abstract:

Schizophrenia is a widespread mental disease with a prevalence of about 1% in the world populationThere is therefore a need for pharmacogenomic studies into the factors affecting response of schizophreniaWe also discuss the genome-wide pharmacogenomic study of schizophrenia and review the current state of

Keywords： pharmacogenomics epigenetics schizophrenia antipsychotics

HTML PDF Collect

Genetic association between the polymorphism of cytosolic PLA2 gene family and schizophrenia

Qiong YU PhD, Xiang-Fei MENG PhD, Jie-Ping SHI, Ya-Qin YU PhD,

Frontiers of Medicine 2010, Volume 4, Issue 1, Pages 101-105 doi: 10.1007/s11684-010-0017-6

Abstract: genetic association between the polymorphism of cytosolic phospholipase A2 (cPLA2) family genes and schizophreniacPLA2 family genes among 201 pedigrees consisting of fathers, mothers and affected offsprings with schizophreniaHRR and TDT showed that the ten SNPs were not associated with schizophrenia (>0.05).Analysis for haplotype transmission showed that no haplotype system was associated with schizophreniaOur data suggest that many loci in the cPLA2 family genes may be associated with schizophrenia.

Keywords： schizophrenia cytosolic phospholipase A2 ligase detection reaction polymorphism