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2017 1

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APL 1

ATRA 1

PML/RARα 1

PU.1 1

S100A9 S100A9 1

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Regulatory mechanism and functional analysis of

Yonglan Zhu,Fang Zhang,Shanzhen Zhang,Wanglong Deng,Huiyong Fan,Haiwei Wang,Ji Zhang

Frontiers of Medicine 2017, Volume 11, Issue 1,   Pages 87-96 doi: 10.1007/s11684-016-0469-4

Abstract: quantitative PCR to determine whether PML/RARα affects the expression of in NB4 and PR9 cells upon ATRAResults showed that was an ATRA-responsive gene, and PML/RARα was necessary for the ATRA-inducedIn addition, PU.1 could bind to the promoter of , especially when treated with ATRA in NB4 cells, andCollectively, our data indicated that PML/RARα and PU.1 were necessary for the ATRA-induced expression

Keywords： S100A9 S100A9     PU.1     PML/RARα     ATRA     APL    

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Regulatory mechanism and functional analysis of

Yonglan Zhu,Fang Zhang,Shanzhen Zhang,Wanglong Deng,Huiyong Fan,Haiwei Wang,Ji Zhang

Journal Article