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Function of Slit/Robo signaling in breast cancer

Feng Gu,Yongjie Ma,Jiao Zhang,Fengxia Qin,Li Fu

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 431-436 doi: 10.1007/s11684-015-0416-9

Abstract: Furthermore, loss of Slit proteins or their Robo receptors upregulates the CXCL12/CXCR4 signaling axismigration of breast cancer cells not only by mediating the phosphorylation of the downstream molecules of CXCL12/CXCR4 and srGAPs, such as PI3K/Src, RAFTK/ Pyk2, and CDC42, but also by regulating the activities of

Keywords： Slit/Robo     hypermethylation     β-catenin     CXCL12/CXCR4     migration    

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Facile controlled synthesis of hierarchically structured mesoporous Li4Ti5O12/C/rGO composites as high-performance

Cehuang FU, Shuiyun SHEN, Ruofei WU, Xiaohui YAN, Guofeng XIA, Junliang ZHANG

Frontiers in Energy 2022, Volume 16, Issue 4,   Pages 607-612 doi: 10.1007/s11708-021-0798-0

Abstract: In this paper, a facile strategy is proposed to controllably synthesize mesoporous Li4Ti5O12/C nanocomposite embedded in graphene matrix as lithium-ion battery anode via theco-assembly of Li4Ti5O12 (LTO) precursor, GO, and phenolic resin.

Keywords： Li4Ti5O12     phenolic-resin-based carbon     mesoporous composite     graphene    

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Influence of the intensity and loading time of direct current electric field on the directional migration of rat bone marrow mesenchymal stem cells

Xiaoyu Wang,Yuxuan Gao,Haigang Shi,Na Liu,Wei Zhang,Hongbo Li

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 286-296 doi: 10.1007/s11684-016-0456-9

Abstract: (DCEF), (2) the optimal DCEF intensity and duration, and (3) the possible regulatory role of SDF-1/CXCR4showed that rBMSCs migrated to the positive electrode of the DCEF, and that the DCEF of 200 mV/mm for 4Moreover, when CXCR4 was inhibited, rBMSC migration due to DCEF was partially blocked.A DCEF of 200 mV/mm for 4 h was recommended because of its ability to promote rBMSC migration, proliferationThe SDF-1/CXCR4 signaling pathway may play an important role in regulating the DCEF-induced migration

Keywords： DCEF     migration     osteogenesis differentiation     rBMSCs     SDF-1/CXCR-4    

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Advances of 12th CAPS research symposium: young chemists and chemical engineers fronts

Guoping Hu, Baiqian Dai

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 3,   Pages 461-463 doi: 10.1007/s11705-020-2026-6

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Introduction to the special section on the 12

Zhen-Min CHENG

Frontiers of Chemical Science and Engineering 2009, Volume 3, Issue 1,   Pages 1-1 doi: 10.1007/s11705-009-0003-1

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ThMn12-Type Alloys for Permanent Magnets Review

G.C. Hadjipanayis, A.M. Gabay, A.M. Schönhöbel, A. Martín-Cid, J.M. Barandiaran, D. Niarchos

Engineering 2020, Volume 6, Issue 2,   Pages 140-146 doi: 10.1016/j.eng.2018.12.011

Abstract:

Iron-rich compounds with the tetragonal ThMn12-type structure have the potential to meetdevelopment of underlying magnetic material, this gap has always been unusually large for ThMn12A controlled crystallization of the initially suppressed ThMn12-type phase makes "bulkSm-Fe-V alloys (in which it has been known since the 1990s), but also is in La-added (Ce,Sm)(Fe,Ti)12Mechanochemically synthesized (Sm,Zr)(Fe,Si)12 and (Sm,Zr)(Fe,Co,Ti)12 powders

Keywords： Permanent magnets     Rare earths permanent magnets     ThMn12 structure    

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Survey of autonomous guidance methods for powered planetary landing Review

Song, Cong Wang, Stephan Theil, David Seelbinder, Marco Sagliano, Xin-fu Liu, Zhi-jiang Shao,zycalt12

Frontiers of Information Technology & Electronic Engineering 2020, Volume 21, Issue 5,   Pages 649-808 doi: 10.1631/FITEE.1900458

Abstract: This paper summarizes the s (AGMs) for on celestial surfaces. We first review the development of guidance methods, focusing on their contributions for dealing with constraints and enhancing computational efficiency. With the increasing demand for reusable launchers and more scientific returns from space exploration, has become a basic requirement. Unlike the kilometer-level precision for previous activities, the position accuracy of future planetary landers is within tens of meters of a target respecting all constraints of velocity and attitude, which is a very difficult task and arouses renewed interest in AGMs. This paper states the generalized three- and six-degree-of-freedom optimization problems in the phase and compares the features of three typical scenarios, i.e., the lunar, Mars, and Earth landing. On this basis, the paper details the characteristics and adaptability of AGMs by comparing aspects of analytical guidance methods, numerical optimization algorithms, and learning-based methods, and discusses the convexification treatment and solution strategies for non-convex problems. Three key issues related to AGM application, including physical feasibility, model accuracy, and real-time performance, are presented afterward for discussion. Many space organizations, such as those in the United States, China, France, Germany, and Japan, have also developed free-flying demonstrators to carry out related research. The guidance methods which have been tested on these demonstrators are briefly introduced at the end of the paper.

Keywords： 自主制导方法；定点软着陆；动力下降；非线性规划    

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Growth suppression of colorectal cancer expressing S492R EGFR by monoclonal antibody CH12

Qiongna Dong, Bizhi Shi, Min Zhou, Huiping Gao, Xiaoying Luo, Zonghai Li, Hua Jiang

Frontiers of Medicine 2019, Volume 13, Issue 1,   Pages 83-93 doi: 10.1007/s11684-019-0682-z

Abstract: EGFR accelerate the growth of CRC cells in vitro and in vivo and monoclonal antibody CH12Furthermore, mAb CH12 showed significantly stronger growth suppression activities and induced a moreantibody-dependent cellular cytotoxicity effect on CRC cells bearing S492R EGFR than mAb C225. mAb CH12Thus, mAb CH12 may be a promising therapeutic agent in treating patients with CRC bearing an S492R EGFR

Keywords： S492R EGFR ectodomain mutation     colorectal cancer     mAb CH12     immunnotherapy    

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Progress and Prospect of Semiconductor Silicon Wafers in China

Zhang Guohu, Xiao Qinghua, Ma Fei

Strategic Study of CAE 2023, Volume 25, Issue 1,   Pages 68-78 doi: 10.15302/J-SSCAE-2023.01.002

Abstract: This study focuses on the market-dominant 8-inch and 12-inch silicon wafers, analyzes the developmentimplementation and sustainability, (3) supporting the coordinated development of the industrial chain, and (4)

Keywords： semiconductor silicon wafer     8 inches     12 inches     industry synergy     advanced processing    

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Poor adherence to P2Y12 antagonists increased cardiovascular risks in Chinese PCI-treated patients

Yang Sun,Chenze Li,Lina Zhang,Dong Hu,Xudong Zhang,Ting Yu,Min Tao,Dao Wen Wang,Xiaoqing Shen

Frontiers of Medicine 2017, Volume 11, Issue 1,   Pages 53-61 doi: 10.1007/s11684-017-0502-2

Abstract: All patients were followed up at the 1st, 6th, and 12th month of discharge while recording ATM and majorcoronary artery bypass grafting (CABG) alone had significantly lower proportion of high adherence to P2Y12Moreover, in patients undergoing PCI, high adherence to P2Y12 antagonists decreased the risk of MACEHigh adherence to P2Y12 antagonists was associated with lower risk of MACE.

Keywords： acute coronary syndromes     adherence to secondary prevention medications     clinical outcome    

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Structure style selection and key structural design of herringbone steel middle pylon of three-pylon suspension bridge

Hua Xin,Han Dazhang,Zhou Yanfeng,Xu Ruifeng

Strategic Study of CAE 2010, Volume 12, Issue 4,   Pages 37-42

Abstract:

The total stiffness of a three-pylon suspension bridge is relatively small. The middle pylon structure of a three-pylon suspension bridge has great influence on the mechanical behavior of the whole bridge. The contradiction between the slip factor of main cable on the top of pylon and the ratios of the deflection to span of the bridge needs to be solved. Based on the analysis of the characteristics and structural behavior of middle pylon of Taizhou Bridge, structure selection of the pylon is done and longitudinal herringbone steel pylon is taken. The structure design of steel pylon and process with key structures, which include weld design for thick plates, structure dispose of branching nodes, connection type between the bottom of steel pylon and concrete bearing platform are introduced. The longitudinal blocking partition design based on crane capacity is also introduced.

Keywords： suspension bridge     steel middle pylon     structure style selection     key structural     design中国工程科学2010年第12卷第4期    

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AC-DC Power Integration Techniques

Ma Weiming

Strategic Study of CAE 2002, Volume 4, Issue 12,   Pages 53-59

Abstract: electric power integration, wherein the stator with one set of 3-phase AC winding and another set of 12together with a rotor having a d-axis field winding and a q-axis stabilizing winding, is combined with a 12Due to complete electrical separation of the AC and DC circuits and usage of the properly designed 12The principle and methods for on-line real time fault diagnosis of the diodes in the 12-phase rectifier

Keywords： electric power integration     double-winding AC - DC generator     12-phase rectification     simultaneous AC and    

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Wheat Blast Pathogen Magnaporthe Oryzae Triticum Pathotype Using Genome-Specific Primers and Cas12a-mediated Article

Houxiang Kang, Ye Peng, Kangyu Hua, Yufei Deng, Maria Bellizzi, Dipali Rani Gupta, Nur Uddin Mahmud, Alfredo S. Urashima, Sanjoy Kumar Paul, Gary Peterson, Yilin Zhou, Xueping Zhou, Md Tofazzal Islam, Guo-Liang Wang

Engineering 2021, Volume 7, Issue 9,   Pages 1326-1335 doi: 10.1016/j.eng.2020.07.016

Abstract: Following this, we used the Cas12a protein and guide RNAs (gRNAs) to target the MoT-6098 and MoT-6099The activated Cas12a showed indiscriminate single-stranded DNase (ssDNAase) activity.We then combined target-dependent Cas12a ssDNase activation with recombinase polymerase amplification

Keywords： Wheat blast     Magnaporthe oryzae     Triticum Cas12a     Nucleic acid rapid lateral flow immunoassay     Field    

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ZnFe2O4/BiVO4 Z-scheme heterojunction for efficient visible-light photocatalytic

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 11,   Pages 1728-1740 doi: 10.1007/s11705-023-2322-z

Abstract: A novel Z-scheme ZnFe2O4/BiVO4 heterojunction photocatalyst was successfullyCompared with the single-phase counterparts, ZnFe2O4/BiVO4 demonstratedConsequently, the 30% ZnFe2O4/BiVO4 catalyst afforded a degradationorganic carbon removal rate of 50%, which is an excellent activity compared with ever reported BiVO42O4/BiVO4 heterojunctions were quite

Keywords： ZnFe2O4/BiVO4     Z-scheme heterojunction     photocatalytic degradation    

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Li4SiO4-coated LiNi0.5Mn1.5O4 as the high performance

Shifeng YANG, Wenfeng REN, Jian CHEN

Frontiers in Energy 2017, Volume 11, Issue 3,   Pages 374-382 doi: 10.1007/s11708-017-0494-2

Abstract: The preparation of Li SiO -coated LiNi Mn O materials by sintering the SiO -coated nickel-manganese oxides with lithium salts using abundant and low-cost sodium silicate as the silicon source was reported. The samples were characterized by X-ray diffraction, scanning electron microscopy and transmission electron microscopy. It was found that a uniform and complete SiO coating layer could be obtained at a suitable pH value of 10, which transformed to a good Li SiO coating layer afterwards. When used as the cathode materials for lithium-ion batteries, the Li SiO -coated LiNi Mn O samples deliver a better electrochemical performance in terms of the discharge capacity, rate capability, and cycling stability than that of the pristine material. It can still deliver 111.1 mAh/g at 20 C after 300 cycles, with a retention ratio of 93.1% of the stable capacity, which is far beyond that of the pristine material (101.3 mAh/g, 85.6%).

Keywords： lithium-ion batteries     cathode material     LiNi0.5Mn1.5O4     lithium-ion conductor    

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Title Author Date Type Operation

Function of Slit/Robo signaling in breast cancer

Feng Gu,Yongjie Ma,Jiao Zhang,Fengxia Qin,Li Fu

Journal Article

Facile controlled synthesis of hierarchically structured mesoporous Li4Ti5O12/C/rGO composites as high-performance

Cehuang FU, Shuiyun SHEN, Ruofei WU, Xiaohui YAN, Guofeng XIA, Junliang ZHANG

Journal Article

Influence of the intensity and loading time of direct current electric field on the directional migration of rat bone marrow mesenchymal stem cells

Xiaoyu Wang,Yuxuan Gao,Haigang Shi,Na Liu,Wei Zhang,Hongbo Li

Journal Article

Advances of 12th CAPS research symposium: young chemists and chemical engineers fronts

Guoping Hu, Baiqian Dai

Journal Article

Introduction to the special section on the 12

Zhen-Min CHENG

Journal Article

ThMn12-Type Alloys for Permanent Magnets

G.C. Hadjipanayis, A.M. Gabay, A.M. Schönhöbel, A. Martín-Cid, J.M. Barandiaran, D. Niarchos

Journal Article

Survey of autonomous guidance methods for powered planetary landing

Song, Cong Wang, Stephan Theil, David Seelbinder, Marco Sagliano, Xin-fu Liu, Zhi-jiang Shao,zycalt12

Journal Article

Growth suppression of colorectal cancer expressing S492R EGFR by monoclonal antibody CH12

Qiongna Dong, Bizhi Shi, Min Zhou, Huiping Gao, Xiaoying Luo, Zonghai Li, Hua Jiang

Journal Article

Progress and Prospect of Semiconductor Silicon Wafers in China

Zhang Guohu, Xiao Qinghua, Ma Fei

Journal Article

Poor adherence to P2Y12 antagonists increased cardiovascular risks in Chinese PCI-treated patients

Yang Sun,Chenze Li,Lina Zhang,Dong Hu,Xudong Zhang,Ting Yu,Min Tao,Dao Wen Wang,Xiaoqing Shen

Journal Article

Structure style selection and key structural design of herringbone steel middle pylon of three-pylon suspension bridge

Hua Xin,Han Dazhang,Zhou Yanfeng,Xu Ruifeng

Journal Article

AC-DC Power Integration Techniques

Ma Weiming

Journal Article

Wheat Blast Pathogen Magnaporthe Oryzae Triticum Pathotype Using Genome-Specific Primers and Cas12a-mediated

Houxiang Kang, Ye Peng, Kangyu Hua, Yufei Deng, Maria Bellizzi, Dipali Rani Gupta, Nur Uddin Mahmud, Alfredo S. Urashima, Sanjoy Kumar Paul, Gary Peterson, Yilin Zhou, Xueping Zhou, Md Tofazzal Islam, Guo-Liang Wang

Journal Article

ZnFe2O4/BiVO4 Z-scheme heterojunction for efficient visible-light photocatalytic

Journal Article

Li4SiO4-coated LiNi0.5Mn1.5O4 as the high performance

Shifeng YANG, Wenfeng REN, Jian CHEN

Journal Article