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Frontiers of Medicine Pages 1006-1009 doi: 10.1007/s11684-023-1000-3
Keywords: family craniofacial microsomia Identification novel mutations
Frontiers of Medicine 2023, Volume 17, Issue 1, Pages 18-42 doi: 10.1007/s11684-022-0976-4
Keywords: non-small cell lung cancer driver mutations treatment strategy resistant mechanism immune-checkpoint
Characteristics of compensatory mutations in the
Shengfen Wang, Yang Zhou, Bing Zhao, Xichao Ou, Hui Xia, Yang Zheng, Yuanyuan Song, Qian Cheng, Xinyang Wang, Yanlin Zhao
Frontiers of Medicine 2020, Volume 14, Issue 1, Pages 51-59 doi: 10.1007/s11684-019-0720-x
Keywords: tuberculosis drug resistance compensatory mutations transmission
Du Yan, Han Xue, Pu Rui, Xie Jiaxin, Zhang Yuwei, Cao Guangwen
Frontiers of Medicine 2014, Volume 8, Issue 2, Pages 217-226 doi: 10.1007/s11684-014-0326-2
Keywords: hepatocellular carcinoma (HCC) interaction miRNA-122-binding site IL-1A rs3783553 hepatitis B virus (HBV) mutations
Frontiers of Medicine 2022, Volume 16, Issue 4, Pages 627-636 doi: 10.1007/s11684-020-0815-4
Keywords: RUNX1 gene mutation acute myeloid leukemia transcriptional repression DNA methylation
Genomic Mutations within the Host Microbiome: Adaptive Evolution or Purifying Selection Review
Jiachao Zhang,Rob Knight,
Engineering 2023, Volume 20, Issue 1, Pages 96-102 doi: 10.1016/j.eng.2021.11.018
Keywords: Gut microbiota Genomic mutations Adaptive evolution Purifying selection Single-nucleotide variants
Jia-Xin XIE, Jian-Hua YIN, Qi ZHANG, Rui PU, Wen-Ying LU, Hong-Wei ZHANG, Guang-Wen CAO, Jun ZHAO, Hong-Yang WANG,
Frontiers of Medicine 2010, Volume 4, Issue 4, Pages 419-429 doi: 10.1007/s11684-010-0160-0
Keywords: hepatitis B virus hepatocellular carcinoma mutation genotype haplotype
Molecular pathogenesis of acute myeloid leukemia: A diverse disease with new perspectives
Felicitas THOL, Arnold GANSER
Frontiers of Medicine 2010, Volume 4, Issue 4, Pages 356-362 doi: 10.1007/s11684-010-0220-5
Keywords: acute myeloid leukemia mutations risk stratification
Genetic evidence in planar cell polarity signaling pathway in human neural tube defects
Chunquan Cai, Ouyan Shi
Frontiers of Medicine 2014, Volume 8, Issue 1, Pages 68-78 doi: 10.1007/s11684-014-0308-4
Neural tube defects (NTDs) are a group of birth anomalies having a profound physical, emotional, and financial effects on families and communities. Their etiology is complex, involving environmental and genetic factors that interact to modulate the incidence and severity of the developing phenotype. The planar cell polarity (PCP) pathway controls the process of convergent extension (CE) during gastrulation and neural tube closure and has been implicated in the pathogenesis of NTDs in animal models and human cohorts. This review summarizes the cumulative results of recent studies on PCP signaling pathway and human NTDs. These results demonstrate that PCP gene alterations contribute to the etiology of human NTDs.
Keywords: planar cell polarity neural tube defects rare mutations
Emerging molecular subtypes and therapeutic targets in B-cell precursor acute lymphoblastic leukemia
Jianfeng Li, Yuting Dai, Liang Wu, Ming Zhang, Wen Ouyang, Jinyan Huang, Saijuan Chen
Frontiers of Medicine 2021, Volume 15, Issue 3, Pages 347-371 doi: 10.1007/s11684-020-0821-6
Keywords: BCP-ALL subtypes translocation aneuploidy sequence mutations
Research progress on human infection with avian influenza H7N9
Xiaoxin Wu, Lanlan Xiao, Lanjuan Li
Frontiers of Medicine 2020, Volume 14, Issue 1, Pages 8-20 doi: 10.1007/s11684-020-0739-z
Keywords: H7N9 pandemic epidemiology mutations vaccine influenza
Liru Qiu, Fengjie Yang, Yonghua He, Huiqing Yuan, Jianhua Zhou
Frontiers of Medicine 2018, Volume 12, Issue 5, Pages 550-558 doi: 10.1007/s11684-017-0567-y
Cystic fibrosis (CF) is a fatal autosomal-recessive disease caused by mutations in the CF transmembraneThe compound heterozygous mutations of the CFTR gene were detected in two infants, and a homozygousAmong the six identified mutations, two are novel point mutations (c.1526G>C and c.3062C>T) that
Keywords: cystic fibrosis pseudo-Bartter syndrome hypokalemic alkalosis CFTR gene mutations infants diagnosis
Title Author Date Type Operation
Identification of novel mutations in and in a family with craniofacial microsomia: evidence of digenic
Journal Article
Treatment of advanced non-small cell lung cancer with driver mutations: current applications and future
Journal Article
Characteristics of compensatory mutations in the
Shengfen Wang, Yang Zhou, Bing Zhao, Xichao Ou, Hui Xia, Yang Zheng, Yuanyuan Song, Qian Cheng, Xinyang Wang, Yanlin Zhao
Journal Article
122-binding site polymorphism at the interleukin-1 α gene and its interaction with hepatitis B virus mutations
Du Yan, Han Xue, Pu Rui, Xie Jiaxin, Zhang Yuwei, Cao Guangwen
Journal Article
Distinct gene expression pattern of mutations coordinated by target repression and promoter hypermethylation
Journal Article
Genomic Mutations within the Host Microbiome: Adaptive Evolution or Purifying Selection
Jiachao Zhang,Rob Knight,
Journal Article
Association of novel mutations and heplotypes in the preS region of hepatitis B virus with hepatocellular
Jia-Xin XIE, Jian-Hua YIN, Qi ZHANG, Rui PU, Wen-Ying LU, Hong-Wei ZHANG, Guang-Wen CAO, Jun ZHAO, Hong-Yang WANG,
Journal Article
Molecular pathogenesis of acute myeloid leukemia: A diverse disease with new perspectives
Felicitas THOL, Arnold GANSER
Journal Article
Genetic evidence in planar cell polarity signaling pathway in human neural tube defects
Chunquan Cai, Ouyan Shi
Journal Article
Emerging molecular subtypes and therapeutic targets in B-cell precursor acute lymphoblastic leukemia
Jianfeng Li, Yuting Dai, Liang Wu, Ming Zhang, Wen Ouyang, Jinyan Huang, Saijuan Chen
Journal Article
Research progress on human infection with avian influenza H7N9
Xiaoxin Wu, Lanlan Xiao, Lanjuan Li
Journal Article