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Fabrication and performance of PEN SOFCs with proton-conducting electrolyte

ZHONG Li, LUO Jingli, Karl Chuang

Frontiers of Chemical Science and Engineering 2007, Volume 1, Issue 1,   Pages 40-44 doi: 10.1007/s11705-007-0008-6

Abstract: A positive-electrolyte-negative (PEN) assembly solid oxide fuel cell (SOFC) with a thin electrolyte filmand cathode catalysts were pressed simultaneously and formed with the fabrication of nano-composite electrolyteThis design offered some advantageous configurations that diminished ohmic resistance between electrolyteimproved the performance of SOFC due to the reduction of membrane thickness and good contact between electrolytecm and 130 mW " cm for the PEN configuration with a Mo-Ni-S-based composite anode, nano-composite electrolyte

Keywords: proton-conducting     positive-electrolyte-negative     temperature operation     Mo-Ni-S-based composite     advantageous    

Prognostic value of the 21-gene recurrence score in ER-positive, HER2-negative, node-positive breastcancer was similar in node-negative diseases: a single-center study of 800 patients

Jiayi Wu, Weiqi Gao, Xiaosong Chen, Chunxiao Fei, Lin Lin, Weiguo Chen, Ou Huang, Siji Zhu, Jianrong He, Yafen Li, Li Zhu, Kunwei Shen

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 621-628 doi: 10.1007/s11684-020-0738-0

Abstract: significance of the 21-gene recurrence score (RS) in Chinese patients with pN0-1, estrogen receptor-positive(ER ), human epidermal growth factor receptor 2-negative (HER2 ) breast cancer.

Keywords: early breast cancer     21-gene assay     recurrence score     prognosis    

Overcoming resistance to endocrine therapy in hormone receptor-positive human epidermal growth factorreceptor 2-negative (HR

Wenjie Zhu, Binghe Xu

Frontiers of Medicine 2021, Volume 15, Issue 2,   Pages 208-220 doi: 10.1007/s11684-020-0795-4

Abstract: New targeted therapies have been developed to overcome resistance to endocrine therapy (ET) and improve the outcome of HR /HER2 advanced breast cancer (ABC). We conducted a meta-analysis and systemic review on randomized controlled trials evaluating various targeted therapies in combination with ET in HR /HER2 ABC. PUBMED and EMBASE databases were searched for eligible trials. Hazard ratios (HRs) for progression-free survival (PFS), odds ratios (ORs) for objective response rate (ORR), clinical benefit rate (CBR), and toxicity were meta-analyzed. Twenty-six studies with data on 10 347 patients were included and pooled. The addition of cyclin-dependent kinase 4/6 inhibitors to ET significantly improved median PFS (pooled HR= 0.547, <0.001), overall survival (pooled HR= 0.755, <0.001), and tumor response rates (ORR, pooled OR= 1.478, <0.001; CBR, pooled OR= 1.201, <0.001) with manageable toxicities (pooled OR= 3.280, <0.001). The mammalian targets of rapamycin inhibitors and exemestane were not clinically beneficial for this pooled population including ET-naïve and ET-resistant patients. Moderate improvement in PFS (pooled HR= 0.686, <0.001) yet pronounced toxicities (pooled OR= 2.154, <0.001) were noted in the combination of phosphatidylinositol-4,5-bisphosphate 3-kinase inhibitors with fulvestrant. Future studies are warranted to optimize the population and the dosing sequence of these available options.

Keywords: endocrine-resistant     HR+/HER2- advanced breast cancer     randomized clinical trials     meta-analysis     targeted therapy    

Molecular epidemiology of Cryptococcus neoformans species complex isolates from HIV-positive and HIV-negative

Min CHEN MM, Wei-Hua PAN MD, Wan-Qing LIAO MM, Xiao-Ran LI BS, Bi-Wei FENG BS, Zhe-Xue QUAN PhD, Shao-Xi WU MD, Xiao-Ping TANG MD, Zhi-Rong YAO MD,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 117-126 doi: 10.1007/s11684-010-0011-z

Abstract: species complex isolates and their clinical manifestations among human immunodeficiency virus (HIV)-positiveand HIV-negative patients in southeast China in the past 15 years.In HIV-negative patients, the majority of the clinical isolates were grouped into molecular types VNIThese results suggest that both HIV-positive and HIV-negative cryptococcal patients in the southeastNo strains were found in HIV-positive patients.

Keywords: Cryptococcus neoformans     Cryptococcus gattii     cryptococcosis     molecular epidemiology     molecular type     mating type    

Localized high-concentration electrolytes for lithium metal batteries: progress and prospect

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 10,   Pages 1354-1371 doi: 10.1007/s11705-022-2286-4

Abstract: With the increasing development of digital devices and electric vehicles, high energy-density rechargeable batteries are strongly required. As one of the most promising anode materials with an ultrahigh specific capacity and extremely low electrode potential, lithium metal is greatly considered an ideal candidate for next-generation battery systems. Nevertheless, limited Coulombic efficiency and potential safety risks severely hinder the practical applications of lithium metal batteries due to the inevitable growth of lithium dendrites and poor interface stability. Tremendous efforts have been explored to address these challenges, mainly focusing on the design of novel electrolytes. Here, we provide an overview of the recent developments of localized high-concentration electrolytes in lithium metal batteries. Firstly, the solvation structures and physicochemical properties of localized high-concentration electrolytes are analyzed. Then, the developments of localized high-concentration electrolytes to suppress the formation of dendritic lithium, broaden the voltage window of electrolytes, enhance safety, and render low-temperature operation for robust lithium metal batteries are discussed. Lastly, the remaining challenges and further possible research directions for localized high-concentration electrolytes are outlined, which can promisingly render the practical applications of lithium metal batteries.

Keywords: high-concentration electrolyte     localized high-concentration electrolyte     lithium metal battery     solidelectrolyte interphase     dendrite    

Decitabine induces -mediated immune responses in p53-mutated triple-negative breast cancer: a clinical

Frontiers of Medicine doi: 10.1007/s11684-023-1016-8

Abstract: Here, we reposition decitabine for triple-negative breast cancer (TNBC), a subtype with frequent p53

Keywords: p53 mutation     triple-negative breast cancer     decitabine     DNMT1     IRF7     innate immune response    

Boosting the direct conversion of NHHCO electrolyte to syngas on Ag/Zn zeolitic imidazolate framework

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 9,   Pages 1196-1207 doi: 10.1007/s11705-022-2289-1

Abstract: which were used for the first time for boosting the direct conversion of NH4HCO3 electrolyteIts activity is comparable to that of the CO2-saturated NH4HCO3 electrolyte

Keywords: Ag catalyst     zeolitic imidazolate framework     CO2 electroreduction     ammonium bicarbonate electrolyte    

A review on the development of electrolytes for lithium-based batteries for low temperature applications

Frontiers in Energy 2023, Volume 17, Issue 1,   Pages 43-71 doi: 10.1007/s11708-022-0853-5

Abstract: cosolvents, additives, and salts have been researched to fine tune the conductivity, solvation, and solid-electrolyteWith these objectives in mind, tailoring of the electrolyte with higher-capacity materials such as lithiumThis review paper highlights the progression of electrolyte research for low temperature performance

Keywords: electrolyte     lithium-ion     low temperature     aerospace     solid-electrolyte interface    

Negative Energy in Faster Than Light Investigation ——An Important Direction to Researches

Huang Zhixun

Strategic Study of CAE 2001, Volume 3, Issue 7,   Pages 42-47

Abstract:

This paper describes a series of expectations and experiments on the negative energy notion.The aim is to find the relation between the faster-than-light research and the negative energy concepts

Keywords: negative energy     faster than light     Casimir's effect     evanescent mode     negative refraction index    

Progress in systemic therapy for triple-negative breast cancer

Hongnan Mo, Binghe Xu

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 1-10 doi: 10.1007/s11684-020-0741-5

Abstract: Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer with a heterogeneous

Keywords: triple-negative breast cancer     immunotherapy     targeted therapy    

Triage for management of cervical high-grade squamous intraepithelial lesion patients with positive margin

Yuya Dou, Xiaodan Zhang, Yang Li, Fenfen Wang, Xing Xie, Xinyu Wang

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 223-228 doi: 10.1007/s11684-017-0517-8

Abstract: triage for the management of cervical high-grade squamous intraepithelial lesion (HSIL) patients with positiveClinico-pathological data of HSIL patients with positive margin by conization were retrospectively collectedNearly half of HSIL patients with positive margin by conization were disease-free in subsequent surgicalspecimens, and those with multiple positive margins may consider re-conization or re-assessment.

Keywords: cervical high-grade squamous intraepithelial lesion     conization     positive surgical margin     hysterectomy    

NO conversion by positive streamer discharge—effects of gas compositions and reaction conditions

HE Wei, ZHU Tianle, LI Jing

Frontiers of Environmental Science & Engineering 2007, Volume 1, Issue 2,   Pages 153-158 doi: 10.1007/s11783-007-0027-z

Abstract: The effects of gas compositions and reaction conditions on NO conversion by positive streamer discharge

Keywords: conversion     streamer discharge     wheel-cylinder     positive streamer    

Recent advances toward high voltage, EC-free electrolytes for graphite-based Li-ion battery

Tong Zhang, Elie Paillard

Frontiers of Chemical Science and Engineering 2018, Volume 12, Issue 3,   Pages 577-591 doi: 10.1007/s11705-018-1758-z

Abstract: graphite anode operation–also required for high energy density batteries–by stabilizing the electrode/electrolyteThis review covers electrolyte compositions, with the widespread use of additives, the change in mainconcentration, but also reports on graphite protection strategies, by coatings or artificial solid electrolyte

Keywords: lithium-ion     electrolyte     solid electrolyte interphase     additives     high voltage     graphite    

Effect of electrolyte concentration on the tribological performance of MAO coatings on aluminum alloys

Chao Wang, Jun Chen, Jihua He, Jing Jiang, Qinyong Zhang

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 6,   Pages 1065-1071 doi: 10.1007/s11705-019-1909-x

Abstract: In order to investigate the effect of the electrolyte concentration on the properties of MAO coatings

Keywords: aluminum alloy     micro-arc oxidation     coating     electrolyte concentration     tribological performance    

To Hold the Economical Time of Biology,to Practicea Positive View of Happiness

Gan Ziheng

Strategic Study of CAE 2007, Volume 9, Issue 2,   Pages 5-11

Abstract: proposition, definition, classification and characteristic of biological economy, also, the importance of positiveIt also discusses which views of happiness should be recommended and how to practice a positive view

Keywords: biological economy     happiness     positive view of happiness    

Title Author Date Type Operation

Fabrication and performance of PEN SOFCs with proton-conducting electrolyte

ZHONG Li, LUO Jingli, Karl Chuang

Journal Article

Prognostic value of the 21-gene recurrence score in ER-positive, HER2-negative, node-positive breastcancer was similar in node-negative diseases: a single-center study of 800 patients

Jiayi Wu, Weiqi Gao, Xiaosong Chen, Chunxiao Fei, Lin Lin, Weiguo Chen, Ou Huang, Siji Zhu, Jianrong He, Yafen Li, Li Zhu, Kunwei Shen

Journal Article

Overcoming resistance to endocrine therapy in hormone receptor-positive human epidermal growth factorreceptor 2-negative (HR

Wenjie Zhu, Binghe Xu

Journal Article

Molecular epidemiology of Cryptococcus neoformans species complex isolates from HIV-positive and HIV-negative

Min CHEN MM, Wei-Hua PAN MD, Wan-Qing LIAO MM, Xiao-Ran LI BS, Bi-Wei FENG BS, Zhe-Xue QUAN PhD, Shao-Xi WU MD, Xiao-Ping TANG MD, Zhi-Rong YAO MD,

Journal Article

Localized high-concentration electrolytes for lithium metal batteries: progress and prospect

Journal Article

Decitabine induces -mediated immune responses in p53-mutated triple-negative breast cancer: a clinical

Journal Article

Boosting the direct conversion of NHHCO electrolyte to syngas on Ag/Zn zeolitic imidazolate framework

Journal Article

A review on the development of electrolytes for lithium-based batteries for low temperature applications

Journal Article

Negative Energy in Faster Than Light Investigation ——An Important Direction to Researches

Huang Zhixun

Journal Article

Progress in systemic therapy for triple-negative breast cancer

Hongnan Mo, Binghe Xu

Journal Article

Triage for management of cervical high-grade squamous intraepithelial lesion patients with positive margin

Yuya Dou, Xiaodan Zhang, Yang Li, Fenfen Wang, Xing Xie, Xinyu Wang

Journal Article

NO conversion by positive streamer discharge—effects of gas compositions and reaction conditions

HE Wei, ZHU Tianle, LI Jing

Journal Article

Recent advances toward high voltage, EC-free electrolytes for graphite-based Li-ion battery

Tong Zhang, Elie Paillard

Journal Article

Effect of electrolyte concentration on the tribological performance of MAO coatings on aluminum alloys

Chao Wang, Jun Chen, Jihua He, Jing Jiang, Qinyong Zhang

Journal Article

To Hold the Economical Time of Biology,to Practicea Positive View of Happiness

Gan Ziheng

Journal Article