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Special issue on “Molecular Sensors and Molecular Logic Gates”
Luling Wu , Tony D. James
《化学科学与工程前沿(英文)》 2022年 第16卷 第1期 页码 1-3 doi: 10.1007/s11705-021-2134-y
《化学科学与工程前沿(英文)》 2022年 第16卷 第2期 页码 168-182 doi: 10.1007/s11705-021-2056-8
关键词: computer-aided molecular design bio-oil additives molecular signature descriptor
Progress on molecular biomarkers and classification of malignant gliomas
null
《医学前沿(英文)》 2013年 第7卷 第2期 页码 150-156 doi: 10.1007/s11684-013-0267-1
Gliomas are the most common primary intracranial tumors in adults. Anaplastic gliomas (WHO grade III) and glioblastomas (WHO grade IV) represent the major groups of malignant gliomas in the brain. Several diagnostic, predictive, and prognostic biomarkers for malignant gliomas have been reported over the last few decades, and these markers have made great contributions to the accuracy of diagnosis, therapeutic decision making, and prognosis of patients. However, heterogeneity in patient outcomes may still be observed, which highlights the insufficiency of a classification system based purely on histopathology. Great efforts have been made to incorporate new information about the molecular landscape of gliomas into novel classifications that may potentially guide treatment. In this review, we summarize three distinctive biomarkers, three most commonly altered pathways, and three classifications based on microarray data in malignant gliomas.
关键词: malignant glioma molecular biomarker IDH1 MGMT molecular classification
Molecular classification and molecular targeted therapy of cancer
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《医学前沿(英文)》 2013年 第7卷 第2期 页码 147-149 doi: 10.1007/s11684-013-0274-2
分子电子学的发展 Review
Paven Thomas Mathew, 房丰洲
《工程(英文)》 2018年 第4卷 第6期 页码 760-771 doi: 10.1016/j.eng.2018.11.001
分子电子学(moletronics)是用分子作为单元对分子电子学器件进行装配。这是一个包含物理、化学、材料科学及工程等学科的多学科交叉领域。分子电子学致力于使硅元件尺寸进一步减小。科学家已经在等效分子器件方面进行了诸多探索性研究。分子电子学在电子以及光子应用中逐渐产生影响,如导电聚合物、光色材料、有机超导体、电致变色材料等。为了满足减小硅片尺寸的需求,研究人员有必要将这种新型技术引入到分子层面。虽然分子层面仪器的实验验证和建模分析是一项艰巨的任务,但分子电子学领域依然出现了突破性进展。本文将对不同分子器件和潜在的适用于不同器件的分子应用结合起来进行讨论,如分子晶体管、分子二极管、分子电容、分子导线和分子绝缘体等。本文简要讨论未来的发展趋势以及介绍各种基于石墨烯已取得一定研究成果的分子仪器。
Wenpo REN, Honggang CHEN, Chaohe YANG, Honghong SHAN,
《化学科学与工程前沿(英文)》 2010年 第4卷 第3期 页码 250-256 doi: 10.1007/s11705-009-0281-7
关键词: dynamic simulation molecular dynamic behavior molecule Adsorption Chromatography
Effect of / molecular structures on pyrolysis performance and heat sink of decalin isomers
《化学科学与工程前沿(英文)》 2023年 第18卷 第1期 doi: 10.1007/s11705-023-2375-z
关键词: endothermic fuel decalin pyrolysis heat sink molecular structure
《环境科学与工程前沿(英文)》 2023年 第17卷 第11期 doi: 10.1007/s11783-023-1740-y
● MD simulations unveil the transport mechanism for TFP-water mixture through CNTs.
关键词: Fluorinated alcohol Carbon nanotube Molecular simulation Fluorine modified
Lin ZHANG, Yan SUN
《化学科学与工程前沿(英文)》 2013年 第7卷 第4期 页码 456-463 doi: 10.1007/s11705-013-1357-y
关键词: adsorption desorption irreversibility protein conformational transition molecular dynamics simulation
Molecular alterations and clinical relevance in esophageal squamous cell carcinoma
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《医学前沿(英文)》 2013年 第7卷 第4期 页码 401-410 doi: 10.1007/s11684-013-0286-y
Esophageal squamous cell carcinoma (ESCC) is one of the most common types of gastrointestinal cancers, and the fourth leading cause of cancer-related deaths in China. Early detection and intervention in time may dramatically increase the survival of the patients by initiating treatment regimens during earlier stages of ESCC or even during precancerous stages. Molecular classification will be useful for subtyping esophageal tumors or precancerous lesions to improve current therapeutics or early intervention of the disease. In this review, we summarize the findings in investigating the molecular alterations and clinical relevance of ESCC.
关键词: esophageal squamous cell carcinoma (ESCC) early detection molecular classification molecular markers
《机械工程前沿(英文)》 2021年 第16卷 第3期 页码 570-579 doi: 10.1007/s11465-021-0642-6
Information gathering and processing with fluorescent molecules
Brian DALY,Jue LING,A. Prasanna de SILVA
《化学科学与工程前沿(英文)》 2014年 第8卷 第2期 页码 240-251 doi: 10.1007/s11705-014-1432-z
关键词: molecular logic molecular computation molecular sensor fluorescent molecular device fluorescent sensor
《化学科学与工程前沿(英文)》 2023年 第17卷 第3期 页码 347-357 doi: 10.1007/s11705-022-2246-z
关键词: reverse separation graphene membrane ethanol/water separation molecular simulation
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《医学前沿(英文)》 2013年 第7卷 第2期 页码 157-171 doi: 10.1007/s11684-013-0272-4
Non-small-cell lung cancer (NSCLC) is the most common cause of premature death among the malignant diseases worldwide. The current staging criteria do not fully capture the complexity of this disease. Molecular biology techniques, particularly gene expression microarrays, proteomics, and next-generation sequencing, have recently been developed to facilitate effectively its molecular classification. The underlying etiology, pathogenesis, therapeutics, and prognosis of NSCLC based on an improved molecular classification scheme may promote individualized treatment and improve clinical outcomes. This review focuses on the molecular classification of NSCLC based on gene expression microarray technology reported during the past decade, as well as their applications for improving the diagnosis, staging and treatment of NSCLC, including the discovery of prognostic markers or potential therapeutic targets. We highlight some of the recent studies that may refine the identification of NSCLC subtypes using novel techniques such as epigenetics, proteomics, or deep sequencing.
关键词: non-small-cell lung cancer molecular typing individualized medicine molecular-targeted therapy gene expression profiling
《化学科学与工程前沿(英文)》 2022年 第16卷 第2期 页码 152-167 doi: 10.1007/s11705-021-2060-z
关键词: molecular property quantum mechanics quantitative structure-property relationship heat of reaction solid-liquid phase equilibrium
标题 作者 时间 类型 操作
Design of bio-oil additives via molecular signature descriptors using a multi-stage computer-aided molecular
期刊论文
Molecular size characterization of heavy oil fractions in vacuum and solution by molecular dynamic simulation
Wenpo REN, Honggang CHEN, Chaohe YANG, Honghong SHAN,
期刊论文
Enhanced separation of tetrafluoropropanol from water via carbon nanotubes membranes: insights from molecular
期刊论文
Effect of ligand chain length on hydrophobic charge induction chromatography revealed by molecular dynamics
Lin ZHANG, Yan SUN
期刊论文
Atomistic understanding of interfacial processing mechanism of silicon in water environment: A ReaxFF molecular
期刊论文
Information gathering and processing with fluorescent molecules
Brian DALY,Jue LING,A. Prasanna de SILVA
期刊论文
Mechanism of ethanol/water reverse separation through a functional graphene membrane: a molecular simulation
期刊论文
Molecular classification of non-small-cell lung cancer: diagnosis, individualized treatment, and prognosis
null
期刊论文