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可靠性灵敏度 3

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Research on acoustic-structure sensitivity using FEM and BEM

ZHANG Jun, ZHAO Wenzhong, ZHANG Weiying

《机械工程前沿（英文）》 2007年 第2卷 第1期   页码 62-67 doi: 10.1007/s11465-007-0010-1

摘要： Acoustic-structure sensitivity is used to predict the change of acoustic pressure when a structure design variable is changed. The sensitivity is significant for reducing noise of structure. Using FEM (finite element method) and BEM (boundary element method) acoustic-structure sensitivity was formulated and presented. The dynamic response and response velocity sensitivity with respect to structure design variable were carried out by using structural FEM, the acoustic response and acoustic pressure sensitivity with respect to structure velocity were carried out by using acoustic BEM. Then, acoustic-structure sensitivity was computed by linking velocity sensitivity in FEM and acoustic sensitivity in BEM. This method was applied to an empty box as an example. Acoustic pressure sensitivity with respect to structure thickness achieved in frequency ranges 1 100 Hz, and its change rule along with stimulating frequency and design variable were analyzed. Results show that acoustic-structure sensitivity method linked with FEM and BEM is effective and correct.

关键词： sensitivity method     BEM     acoustic pressure     pressure sensitivity     frequency    

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Parametric sensitivity analysis of cellular diaphragm wall

Xi CHEN, Wei XU

《结构与土木工程前沿（英文）》 2012年 第6卷 第4期   页码 358-364 doi: 10.1007/s11709-012-0177-3

摘要： The deformation law of the cellular diaphragm wall in deep foundation pits was studied through numerical simulation. Based on the example of the dock wall in engineering, the full three-dimensional finite element model was used to simulate the excavation of the foundation pit. Interaction between the cellular diaphragm wall and the soil was also taken into account in the calculation. The results indicated that the maximum lateral displacement, which is the evaluation index of sensitivity analysis, appeared on the top of the interior longitudinal wall with an excavation depth of 10 m. The centrifuge model test was carried out to study the deformation regulation for a cellular diaphragm wall. The most sensitive factor was found by adjusting the length of the partition wall, the spacing of the partition wall and the thickness of the wall. In the end, a suggestion was proposed to optimize the cellular diaphragm by adjusting the length of the partition wall.

关键词： cellular diaphragm wall     sensitivity analysis     optimization     centrifuge model test    

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Probability strength design of steam turbine blade and sensitivity analysis with respect to random parameters

DUAN Wei

《能源前沿（英文）》 2008年 第2卷 第1期   页码 107-115 doi: 10.1007/s11708-008-0018-1

摘要： Many stochastic parameters have an effect on the reliability of a steam turbine blade during practical operation. To improve the reliability of blade design, it is necessary to take these stochastic parameters into account. An equal cross-section blade is investigated and a finite element model is built parametrically. Geometrical parameters, material parameters and load parameters of the blade are considered as input random variables while the maximum deflection and maximum equivalent stress are output random variables. Analysis file of the blade is compiled by deterministic finite element method and applied to be loop file to create sample points. A quadratic polynomial with cross terms is chosen to regress these samples by step-forward regression method and employed as a surrogate of numerical solver to drastically reduce the number of solvers call. Then, Monte Carlo method is used to obtain the statistical characteristics and cumulative distribution function of the maximum deflection and maximum equivalent stress of the blade. Probability sensitivity analysis, which combines the slope of the gradient and the width of the scatter range of the random input variables, is applied to evaluate how much the output parameters are influenced by the random input parameters. The scatter plots of structural responses with respect to the random input variables are illustrated to analyze how to change the input random variables to improve the reliability of the blade. The results show that combination of the finite element method, the response surface method and Monte Carlo method is an ideal way for the reliability analysis and probability strength design of the blade.

关键词： Probability sensitivity     sensitivity analysis     number     cross-section     statistical    

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Wheel tracking methods to evaluate moisture sensitivity of hot-mix asphalt mixtures

Jie HAN,Harihar Shiwakoti

《结构与土木工程前沿（英文）》 2016年 第10卷 第1期   页码 30-43 doi: 10.1007/s11709-016-0318-1

摘要： Existing test methods to determine moisture sensitivity in hot-mix asphalt (HMA) mixtures are time consuming and inconsistent. This research focused on wheel tracking devices to evaluate moisture sensitivity. The Asphalt Pavement Analyzer (APA) and the Hamburg Wheel Tracking Device (HWTD) were used for this research. Compacted cylindrical samples were fabricated using a Superpave Gyratory compactor. This study selected two most commonly used mixtures, SM-12.5A with PG 64-22 binder in overlay projects and SM-19A mixtures with PG 64-22 binder for major modification projects at Kansas Department of Transportation. Test results show that APA tests could induce stripping in most samples without any anti-stripping agent, which could be identified visually. However, APA results did not indicate any stripping inflection point while the HWTD results showed stripping inflection points, which are important to identify stripping potential of mixtures. The APA results show that wet tests are severe at lower temperatures. The HWTD results show improvement in the performance using anti-stripping agents at later stage. The HWTD test is more effective as a rapid test method in case of determining moisture sensitivity. Laboratory results from this study should be verified and correlated with field performance.

关键词： hot-mix asphalt     moisture sensitivity     rutting     wheel tracking test    

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A surrogate model for uncertainty quantification and global sensitivity analysis of nonlinear large-scale

《结构与土木工程前沿（英文）》 2023年 第17卷 第12期   页码 1813-1829 doi: 10.1007/s11709-023-0007-9

摘要： Full-scale dome structures intrinsically have numerous sources of irreducible aleatoric uncertainties. A large-scale numerical simulation of the dome structure is required to quantify the effects of these sources on the dynamic performance of the structure using the finite element method (FEM). To reduce the heavy computational burden, a surrogate model of a dome structure was constructed to solve this problem. The dynamic global sensitivity of elastic and elastoplastic structures was analyzed in the uncertainty quantification framework using fully quantitative variance- and distribution-based methods through the surrogate model. The model considered the predominant sources of uncertainty that have a significant influence on the performance of the dome structure. The effects of the variables on the structural performance indicators were quantified using the sensitivity index values of the different performance states. Finally, the effects of the sample size and correlation function on the accuracy of the surrogate model as well as the effects of the surrogate accuracy and failure probability on the sensitivity index values are discussed. The results show that surrogate modeling has high computational efficiency and acceptable accuracy in the uncertainty quantification of large-scale structures subjected to earthquakes in comparison to the conventional FEM.

关键词： large-scale dome structure     surrogate model     global sensitivity analysis     uncertainty quantification     structural performance    

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An antibiotic composite electrode for improving the sensitivity of electrochemically active biofilm biosensor

《环境科学与工程前沿（英文）》 2022年 第16卷 第8期 doi: 10.1007/s11783-022-1518-7

摘要：

• Antibiotic azithromycin employed in graphite electrode for EAB biosensor.

关键词： AZM@GP composite electrode     EAB-biosensor     Water quality early-warning    

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Catalytic process modeling and sensitivity analysis of alkylation of benzene with ethanol over MIL-101

Ehsan Rahmani, Mohammad Rahmani

《化学科学与工程前沿（英文）》 2020年 第14卷 第6期   页码 1100-1111 doi: 10.1007/s11705-019-1891-3

摘要： A solvothermal method was used to synthesize MIL-101(Fe) and MIL-88(Fe), which were used for alkylation of benzene. The synthesized catalysts were characterized by X-ray diffraction, Fourier transform infrared spectroscopy, field emission scanning electron microscope, dynamic light scattering, and BET techniques. Metal-organic frameworks (MOFs) were modeled to investigate the catalytic performance and existence of mass transfer limitations. Calculated effectiveness factors revealed absence of internal and external mass transfer. Sensitivity analysis revealed best operating conditions over MIL-101 at 120°C and 5 bar and over MIL-88 at 142°C and 9 bar.

关键词： MOFs     alkylation     ethylbenzene     catalysts pellet model     kinetic model     sensitivity analysis    

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Global sensitivity analysis of certain and uncertain factors for a circular tunnel under seismic action

Nazim Abdul NARIMAN, Raja Rizwan HUSSAIN, Ilham Ibrahim MOHAMMAD, Peyman KARAMPOUR

《结构与土木工程前沿（英文）》 2019年 第13卷 第6期   页码 1289-1300 doi: 10.1007/s11709-019-0548-0

摘要： There are many certain and uncertain design factors which have unrevealed rational effects on the generation of tensile damage and the stability of the circular tunnels during seismic actions. In this research paper, we have dedicated three certain and four uncertain design factors to quantify their rational effects using numerical simulations and the Sobol’s sensitivity indices. Main effects and interaction effects between the design factors have been determined supporting on variance-based global sensitivity analysis. The results detected that the concrete modulus of elasticity for the tunnel lining has the greatest effect on the tensile damage generation in the tunnel lining during the seismic action. In the other direction, the interactions between the concrete density and both of concrete modulus of elasticity and tunnel diameter have appreciable effects on the tensile damage. Furthermore, the tunnel diameter has the deciding effect on the stability of the tunnel structure. While the interaction between the tunnel diameter and concrete density has appreciable effect on the stability process. It is worthy to mention that Sobol’s sensitivity indices manifested strong efficiency in detecting the roles of each design factor in cooperation with the numerical simulations explaining the responses of the circular tunnel during seismic actions.

关键词： shear waves     Sobol’s sensitivity indices     maximum principal stress     maximum overall displacement     tensile damage    

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Predicting lateral displacement caused by seismic liquefaction and performing parametric sensitivity

Nima PIRHADI, Xiaowei TANG, Qing YANG, Afshin ASADI, Hazem Samih MOHAMED

《结构与土木工程前沿（英文）》 2021年 第15卷 第2期   页码 506-519 doi: 10.1007/s11709-021-0677-0

摘要： Lateral displacement due to liquefaction ( ) is the most destructive effect of earthquakes in saturated loose or semi-loose sandy soil. Among all earthquake parameters, the standardized cumulative absolute velocity ( ) exhibits the largest correlation with increasing pore water pressure and liquefaction. Furthermore, the complex effect o fine content( ) at different values has been studied and demonstrated. Nevertheless, these two contexts have not been entered into empirical and semi-empirical models to predict This study bridges this gap by adding to the data set and developing two artificial neural network (ANN) models. The first model is based on the entire range of the parameters, whereas the second model is based on the samples with values that are less than the 28% critical value. The results demonstrate the higher accuracy of the second model that is developed even with less data. Additionally, according to the uncertainties in the geotechnical and earthquake parameters, sensitivity analysis was performed via Monte Carlo simulation (MCS) using the second developed ANN model that exhibited higher accuracy. The results demonstrated the significant influence of the uncertainties of earthquake parameters on predicting

关键词： lateral spreading displacement     cumulative absolute velocity     fine content     artificial neural network     sensitivity analysis     Monte Carlo simulation    

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Reliability and variance-based sensitivity analysis of arch dams during construction and reservoir impoundment

M. Houshmand KHANEGHAHI, M. ALEMBAGHERI, N. SOLTANI

《结构与土木工程前沿（英文）》 2019年 第13卷 第3期   页码 526-541 doi: 10.1007/s11709-018-0495-1

摘要： The static performance of arch dams during construction and reservoir impoundment is assessed taking into account the effects of uncertainties presented in the model properties as well as the loading conditions. Dez arch dam is chosen as the case study; it is modeled along with its rock foundation using the finite element method considering the stage construction. Since previous studies concentrated on simplified models and approaches, comprehensive study of the arch dam model along with efficient and state-of-the-art uncertainty methods are incorporated in this investigation. The reliability method is performed to assess the safety level and the sensitivity analyses for identifying critical input factors and their interaction effects on the response of the dam. Global sensitivity analysis based on improved Latin hypercube sampling is employed in this study to indicate the influence of each random variable and their interaction on variance of the responses. Four levels of model advancement are considered for the dam-foundation system: 1) Monolithic dam without any joint founded on the homogeneous rock foundation, 2) monolithic dam founded on the inhomogeneous foundation including soft rock layers, 3) jointed dam including the peripheral and contraction joints founded on the homogeneous foundation, and 4) jointed dam founded on the inhomogeneous foundation. For each model, proper performance indices are defined through limit-state functions. In this manner, the effects of input parameters in each performance level of the dam are investigated. The outcome of this study is defining the importance of input factors in each stage and model based on the variance of the dam response. Moreover, the results of sampling are computed in order to assess the safety level of the dam in miscellaneous loading and modeling conditions.

关键词： concrete arch dams     reliability     randomness     improved Latin hypercube sampling     variance-based sensitivity analysis     exceedance probability     Sobol′ index    

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Photochemical indicators of ozone sensitivity: application in the Pearl River Delta, China

Lyumeng Ye,Xuemei Wang,Shaofeng Fan,Weihua Chen,Ming Chang,Shengzhen Zhou,Zhiyong Wu,Qi Fan

《环境科学与工程前沿（英文）》 2016年 第10卷 第6期 doi: 10.1007/s11783-016-0887-1

摘要： The distribution of NO - and VOC-sensitive regimes in the PRD are identified. The effectiveness of six popular chemical indicators for discriminating O sensitivity regimes is evaluated. Threshold levels for HCHO/NO , H O /HNO , O /NO , O /NO , O /HNO were derived and verified. The indicators H O /HNO and H O /NO performed best and maintained relatively stable threshold levels. Surface O production has a highly nonlinear relationship with its precursors. The spatial and temporal heterogeneity of O -NO -VOC-sensitivity regimes complicates the control- decision making. In this paper, the indicator method was used to establish the relationship between O sensitivity and assessment indicators. Six popular ratios indicating ozone-precursor sensitivity, HCHO/NO , H O /HNO , O /NO , O /NO , O /HNO , and H O /NO , were evaluated based on the distribution of NO - and VOC-sensitive regimes. WRF-Chem was used to study a serious ozone episode in fall over the Pearl River Delta (PRD). It was found that the south-west of the PRD is characterized by a VOC-sensitive regime, while its north-east is NO -sensitive, with a sharp transition area between the two regimes. All indicators produced good representations of the elevated ozone hours in the episode on 6 November 2009, with H O /HNO being the best indicator. The threshold sensitivity levels for HCHO/NO , H O /HNO , O /NO , O /NO , O /HNO , and H O /NO were estimated to be 0.41, 0.55, 10.2, 14.0, 19.1, and 0.38, respectively. Threshold intervals for the indicators H O /HNO , O /NO , O /NO , O /HNO , and H O /NO were able to identify more than 95% of VOC- and NO -sensitive grids. The ozone episode on 16 November 16 2008 was used to independently verify the results, and it was found that only H O /HNO and H O /NO were able to differentiate the ozone sensitivity regime well. Hence, these two ratios are suggested as the most appropriate indicators for identifying fall ozone sensitivity in the PRD. Since the species used for indicators have seasonal variation, the utility of those indicators for other seasons should be investigated in the future work.

关键词： Ozone     Pearl River Delta (PRD)     Sensitivity regime     Photochemical indicator     Threshold levels    

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Establishment and drug sensitivity evaluation of murine ascites hepatocarcinoma cell line with high lymphatic

Hongying ZHANG, Jianwu TANG, Wenting ZHU, Chunxiu HU, Guowang XU

《医学前沿（英文）》 2009年 第3卷 第2期   页码 119-129 doi: 10.1007/s11684-009-0022-9

摘要： In order to provide a sensitive cell line model for investigating the mechanisms underlying the lymphatic metastasis of tumors and the effect of medicine against cells, a new murine ascites hepatocarcinoma cell line with high lymphatic metastatic potential (Hca-P/L ) was established and the effect of curcumin on biological behavior of Hca-P/L was observed. Murine ascites hepatocarcinoma cell strain with low lymphatic metastatic potential (Hca-P) was subcutaneously inoculated into the medioventral line of a mouse 615 and the first generation of metastatic tumor cells of inguinal lymph node (Hca-P/L ) was obtained. Then, Hca-P/L was screened by the route of mouse foot pad subcutaneously → lymph node → scale-up culture → mouse foot pad subcutaneously for five times consecutively. The sensitivity of two murine ascites hepatocarcinoma cell lines (Hca-P and Hca-P/L ) and two anchorage-dependent human hepatocarcinoma cell lines (SMC7721 and HepG ) to curcumin were studied by use of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay after these cells had been pretreated by curcumin at the concentration of 15-240 μmol/L for 48 h. After pretreatment by curcumin at the maximum non-cytotoxic dose of 15 μmol/L , the effect of curcumin against cell proliferation of Hca-P and Hca-P/L was observed by inverted microscope, cell growth curve and cell population doubling time; the effects of curcumin on cell cycles of Hca-P/L and Hca-P were studied by flow cytometry (FCM). The results showed Hca-P/L spreading to the lymph nodes at multiple sites in mice was screened from Hca-P. The lymph node metastatic rate was 100%. Curcumin had significant growth inhibiting effect on both murine ascites and human hepatocarcinoma cell lines in a dose-dependent manner ( <0. 05). At concentrations of 30-120 μmol/L, curcumin had more inhibition on murine ascites hepatocarcinoma cell lines than on human anchorage-dependent hepatocarcinoma cell lines. At concentrations of 60-240 μmol/L, curcumin had more inhibition on Hca-P/L with (the 50% inhibitory concentration) IC of 51.48 μmol/L than on Hca-P with IC of 90.87 μmol/L. After pretreatment by curcumin at the maximum non-cytotoxic dose of 15 mol/L for 7 days, the proliferations of Hca-P/L and Hca-P were inhibited ( <0.05) in a time-dependent manner ( <0.01) and the population doubling time of Hca-P/L and Hca-P was prolonged ( <0.01), and curcumin had more inhibition on Hca-P/L than on Hca-P ( <0.05). After pretreatment by 15 μmol/L curcumin for 48 h, the morphous of Hca-P/L was influenced more seriously than that of Hca-P and the cell cycle was redistributed with Hca-P/L being blocked in the S phase and Hca-P in the S and G /M phases. Hca-P/L was validated to be more sensitive to curcumin than Hca-P. Hca-P/L is a novel sensitive cell line model for investigating the mechanisms underlying tumor lymphatic metastasis and the effect of the medicine against cells.

关键词： murine ascites hepatocarcinoma cell line     metastasis     curcumin     drug sensitivity    

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Adiponectin: mechanisms and new therapeutic approaches for restoring diabetic heart sensitivity to ischemic

null

《医学前沿（英文）》 2013年 第7卷 第3期   页码 301-305 doi: 10.1007/s11684-013-0283-1

摘要：

Systemic inflammatory response following myocardial ischemia-reperfusion injury (IRI) to a specific organ may cause injuries. Ischemic post-conditioning (IPostC) has emerged as a promising method for myocardial protection against IRI both in experimental and in clinical settings. Enhancement of endogenous nitric oxide (NO) is one of the major mechanisms by which IPostC confers cardioprotection. However, the sensitivity of the diabetic heart to IPostC is impaired and the underlying mechanism is unknown. Adiponectin (APN) is an adipocyte-derived plasma protein with anti-diabetic and anti-inflammatory properties. Plasma levels of APN are decreased in obese subjects and in patients with type 2 diabetes. APN supplementation has been shown to increase NO production and attenuate myocardial IRI in normal (non-diabetic) animals. However, the effect of APN on myocardial injury in diabetic subjects, especially its potential in restoring the sensitivity of the diabetic heart to IPostC has not been investigated. In the current paper, we discussed the possible reasons why the myocardium of diabetic subjects loses sensitivity to IPostC and also highlighted the potential effectiveness and mechanism of APN in restoring IPostC cardioprotection in diabetes. This review proposes to conduct studies that may facilitate the development of novel and optimal therapies to enhance cardioprotection in patients with severe diseases such as diabetes.

关键词： adiponectin     ischemic post-conditioning     ischemia reperfusion injury     diabetes    

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Kinetic energy based model assessment and sensitivity analysis of vortex induced vibration of segmental

Nazim Abdul NARIMAN

《结构与土木工程前沿（英文）》 2017年 第11卷 第4期   页码 480-501 doi: 10.1007/s11709-017-0435-5

摘要： In this paper, semi 3D models for segmental Bridge decks are created in ABAQUS CFD program with the support of MATLAB codes to simulate and analyze vortex shedding generated due to wind excitation through considering the stationary position of the deck. Three parameters (wind speed, deck streamlined length and dynamic viscosity of the air) are dedicated to study their effects on the kinetic energy of the system in addition to the shapes and patterns of the vortices. Two benchmarks from the literature Von Karman and Dyrbye and Hansen are considered to validate the vortex shedding aspects for the CFD models. Good agreement between the results of the benchmarks and the semi 3D models has been detected. Latin hypercube experimental method is dedicated to generate the surrogate models for the kinetic energy of the system and the lift forces. Variance based sensitivity analysis is utilized to calculate the main sensitivity indices and the interaction orders for all the three parameters. The kinetic energy approach performed very well in revealing the rational effects and the roles of each parameter in the generation of vortex shedding and predicting vortex induced vibration of the deck.

关键词： vortex induced vibration     reynolds number     kinetic energy     vorticity     latin hypercube sampling    

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Dependence of error sensitivity of frequency on bias voltage in force-balanced micro accelerometer

Lili CHEN, Wu ZHOU

《机械工程前沿（英文）》 2013年 第8卷 第2期   页码 146-149 doi: 10.1007/s11465-013-0260-z

摘要：

To predict more precisely the frequency of force-balanced micro accelerometer with different bias voltages, the effects of bias voltages on error sensitivity of frequency is studied. The resonance frequency of accelerometer under closed loop control is derived according to its operation principle, and its error sensitivity is derived and analyzed under over etching structure according to the characteristics of Deep Reaction Ion Etching (DRIE). Based on the theoretical results, micro accelerometer is fabricated and tested to study the influences of AC bias voltage and DC bias voltage on sensitivity, respectively. Experimental results indicate that the relative errors between test data and theory data are less than 7%, and the fluctuating value of error sensitivity under the range of voltage adjustment is less than 0.01 μm . It is concluded that the error sensitivity with designed parameters of structure, circuit and process error can be used to predict the frequency of accelerometer with no need to consider the influence of bias voltage.

关键词： Micro-Electro-Mechanical Systems (MEMS)     micro accelerometer     force-balanced micro accelerometer     frequency     error sensitivity    

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标题 作者 时间 类型 操作

Research on acoustic-structure sensitivity using FEM and BEM

ZHANG Jun, ZHAO Wenzhong, ZHANG Weiying

期刊论文

Parametric sensitivity analysis of cellular diaphragm wall

Xi CHEN, Wei XU

期刊论文

Probability strength design of steam turbine blade and sensitivity analysis with respect to random parameters

DUAN Wei

期刊论文

Wheel tracking methods to evaluate moisture sensitivity of hot-mix asphalt mixtures

Jie HAN,Harihar Shiwakoti

期刊论文

A surrogate model for uncertainty quantification and global sensitivity analysis of nonlinear large-scale

期刊论文

An antibiotic composite electrode for improving the sensitivity of electrochemically active biofilm biosensor

期刊论文

Catalytic process modeling and sensitivity analysis of alkylation of benzene with ethanol over MIL-101

Ehsan Rahmani, Mohammad Rahmani

期刊论文

Global sensitivity analysis of certain and uncertain factors for a circular tunnel under seismic action

Nazim Abdul NARIMAN, Raja Rizwan HUSSAIN, Ilham Ibrahim MOHAMMAD, Peyman KARAMPOUR

期刊论文

Predicting lateral displacement caused by seismic liquefaction and performing parametric sensitivity

Nima PIRHADI, Xiaowei TANG, Qing YANG, Afshin ASADI, Hazem Samih MOHAMED

期刊论文

Reliability and variance-based sensitivity analysis of arch dams during construction and reservoir impoundment

M. Houshmand KHANEGHAHI, M. ALEMBAGHERI, N. SOLTANI

期刊论文

Photochemical indicators of ozone sensitivity: application in the Pearl River Delta, China

Lyumeng Ye,Xuemei Wang,Shaofeng Fan,Weihua Chen,Ming Chang,Shengzhen Zhou,Zhiyong Wu,Qi Fan

期刊论文

Establishment and drug sensitivity evaluation of murine ascites hepatocarcinoma cell line with high lymphatic

Hongying ZHANG, Jianwu TANG, Wenting ZHU, Chunxiu HU, Guowang XU

期刊论文

Adiponectin: mechanisms and new therapeutic approaches for restoring diabetic heart sensitivity to ischemic

null

期刊论文

Kinetic energy based model assessment and sensitivity analysis of vortex induced vibration of segmental

Nazim Abdul NARIMAN

期刊论文

Dependence of error sensitivity of frequency on bias voltage in force-balanced micro accelerometer

Lili CHEN, Wu ZHOU

期刊论文