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A novel intravenous general anesthetic--- emulsified isoflurane: from bench to bedside
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《医学前沿(英文)》 2012年 第6卷 第4期 页码 381-387 doi: 10.1007/s11684-012-0229-z
Application of volatile anesthetics greatly alters modern medicine. There are obvious advantages of volatile anesthetics such as strong anesthetic potency, rapid onset and elimination through respiration system. Isoflurane is one of the most widely used volatile anesthetics in clinic. Emulsified isoflurane, the emulsion of isoflurane, is a novel intravenous general anesthetic. With the development of emulsified isoflurane in the past fifteen years, its utility has spread from intravenous general anesthesia to various fields including regional anesthesia, organ protection, as well as anesthetic pharmacological study. In this review, we will summarize literatures of emulsified isoflurane about its history, clinical application and future potential utility in the above mentioned fields.
关键词: emulsified isoflurane (EI) general anesthesia regional anesthesia organ protection anesthetic pharmacological study
Numerical investigation of circle defining curve for two-dimensional problem with general boundaries
Chung Nguyen VAN
《结构与土木工程前沿(英文)》 2019年 第13卷 第1期 页码 92-102 doi: 10.1007/s11709-018-0472-8
关键词: exact geometry circular defining curve general boundaries SBFEM
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《医学前沿(英文)》 2012年 第6卷 第3期 页码 302-306 doi: 10.1007/s11684-012-0194-6
This study was designed to evaluate the effect of tracheal topical anesthesia using EMLA? Cream (EC) coated on the endotracheal tube (ETT) with or without epidural anesthesia (EA) on isoflurane requirement during general anesthesia (GA) and investigate whether EC coated on the ETT with EA was associated with the additive effect compared with the effect when each anesthetic was administered independently. The prospective randomized, double-blinded, and controlled study included 60 ASA I–II patients scheduled for upper abdominal surgery requiring GA. Patients were randomly assigned to one of the following groups: group 1 received GA, group 2 received EC+ GA, group 3 received GA+ EA, and group 4 received EC+ GA+ EA. Isoflurane was administered at the required concentrations to maintain the mean arterial pressure at a level not exceeding 20% of preoperative values. The percentage mean expired concentration (%MEC) was used in calculating the isoflurane requirement. Emergence agitation, postoperative sore throat, and hoarseness were recorded. Groups 2, 3, and 4 exhibited a significant reduction on isoflurane requirement compared with group 1 (P<0.05). The isoflurane requirement evaluated by %MEC decreased by 12%, 38%, and 50% in groups 2, 3, and 4, respectively. The incidence of emergence agitation was significantly lower in groups 2 and 4 than those in groups 1 and 3 (P<0.05). Tracheal topical anesthesia using EC coated on ETT with or without EA reduced the isoflurane requirement during GA, indicating that EC combined with EA exhibited an additive effect on the requirement of general anesthetic.
关键词: EMLA? Cream epidural anesthesia general anesthesia isoflurane lidocaine
Kan ZHANG MM, Wei DONG MM, Ying-Yao CHEN MD,
《医学前沿(英文)》 2010年 第4卷 第2期 页码 134-138 doi: 10.1007/s11684-010-0041-6
关键词: community health general practitioners health management
陈积懋
《中国工程科学》 2000年 第2卷 第4期 页码 64-69
论述了检测复合材料和胶接结构不连续(缺陷)的新型多模综合无损检测技术。该技术以声与超声检测技术为基础,包含五种不同检测模式,用以检测复合材料与胶接结构的失粘、脱粘、分层、疏松、夹芯压皱及其他缺陷。它适用于复合材料与构件的制造、维修和使用现场。它的适用对象范围广泛,几乎覆盖了现有常用的复合材料和胶接结构。它的检测可靠性高,重复精度好。文章还讨论了组成多膜声学综合胶接检测仪的五种不同检测模式的原理,并从我们和国内外同行的大量实践经验出发,说明了综合无损检测技术的巨大发展前景。
General modeling and optimization technique for real-world earth observation satellite scheduling
《工程管理前沿(英文)》 页码 695-709 doi: 10.1007/s42524-023-0263-3
关键词: earth observation satellite scheduling general technique optimization algorithm commercial constellation real-world benchmark
Feasible workspace regions for general two-revolute manipulator
Conghui LIANG, Marco CECCARELLI
《机械工程前沿(英文)》 2011年 第6卷 第4期 页码 397-408 doi: 10.1007/s11465-011-0228-9
In this paper, a topology is presented for feasible workspace regions in general two-revolute manipulators. The design problem and concept of feasible workspace regions have been discussed as linked to each other. Design equations are formulated by arbitrarily prescribing four workspace boundary points. The so-called feasible workspace regions are the intersection of three different sub-regions, which are given by constraint curves as function of the relative positions of three workspace boundary points. By using a parametric study, all topologies for three sub-regions are figured out. Corresponding areas in cross section plane are determined for prescribing the position of a feasible workspace point as function of the topology for sub-regions. A classification has been proposed to determine and to characterize the combination of the topologies for those sub-regions. All topologies for feasible workspace regions are figured out and they are discussed as a design tool. Three general cases are analyzed in details to characterize workspace design capabilities for general two-revolute manipulators.
关键词: workspace two-revolute manipulators topology analysis design
General framework for bridge life cycle design
Junhai MA, Airong CHEN, Jun HE
《结构与土木工程前沿(英文)》 2009年 第3卷 第1期 页码 50-56 doi: 10.1007/s11709-009-0004-7
关键词: bridge whole life design design phase design process general framework
金士尧
《中国工程科学》 2004年 第6卷 第1期 页码 30-36
卫星移动网络是以卫星星座为基本物理架构,通过星际的通信链路形成覆盖全球的天基通信网络。它对社会发展、科技进步以及军队的信息化有着重大的推动作用。由于天网的移动性、通信的偶断性、接入的复杂性以及使用的综合性,都为研制提出了重大的挑战。有必要通过总体概念设计仿真,来进一步验证总体需求、总体方案、关键技术指标和研制的约束条件,形成科学的可行性报告。介绍了卫星移动网络的总体概念,设计了针对天网仿真的平台,并用实例获得卫星移动网络总体概念设计的仿真数据。
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《医学前沿(英文)》 2012年 第6卷 第4期 页码 406-410 doi: 10.1007/s11684-012-0217-3
The esophagus is perfused directly by prominent arteries and may provide a more consistent tissue source for pulse oximetry. The goal of this study was to evaluate the sensitivity and accuracy of an esophageal pulse oximetry probe on patients during controlled hypoxemia in comparison to measurements obtained with conventional pulse oximetry (SpulseO2). Forty-five ASA I–II adult patients were included in this prospective observational study. Nellcor digital oximetric probes were placed on finger tips for SpulseO2 before anesthesia. After tracheal intubation, an esophageal probe was placed in the lower segment of the esophagus for esophageal oximetric monitoring (SoesO2). All patients were disconnected from the breathing circuit to establish a controlled hypoxemia, and were re-connected to the breathing circuit and ventilated with 100% oxygen immediately when SoesO2 dropped to 90%. Matched SoesO2 and SpulseO2 readings were recorded when SoesO2measurements were at 100%, 95%, 90% and the lowest reading. The time for SoesO2 and SpulseO2 to drop from 100% to 95%, 90% and return to 100% was recorded. Oxygen saturation from arterial blood samples (SartO2) was also measured at each time point respectively. The linear correlation coefficient of the regression analysis between SartO2 and SoesO2 was 0.954. The mean±2SD of the difference was 0.3%±4.3% for SoesO2vs. SartO2 and 6.8%±5.6% for SpulseO2vs. SartO2 (P<0.001). The 95% confidence interval for the absolute difference between SoesO2 and SartO2 was 0.3% to 0.7% and 6.2% to 7.4% between SpulseO2 and SartO2. The time to reach 90% saturation measured with SoesO2 was approximately 94 seconds earlier than the SpulseO2 (P<0.001). In conclusion, SoesO2 is more accurate and enables earlier detection of hypoxemia when compared to conventional pulse oximetry during hypoxemia for patients undergoing general anesthesia.
关键词: esophageal pulse oximetry conventional pulse oximetry hypoxemia
刘颖,蒋国平,任菁菁
《中国工程科学》 2019年 第21卷 第2期 页码 74-78 doi: 10.15302/J-SSCAE-2019.02.005
经过近30年的不断探索和实践,我国全科医生队伍建设取得了一定的进展,初步建立了以“5+3”为主、“3+2”为辅的全科医生培养模式,但我国仍面临严重缺乏合格全科医生的情况。本文通过对我国全科医生培养现状的研究,了解到当前我国全科医生岗位缺乏吸引力,全科医生培养制度和体系不够完善,缺乏完善的过程考核机制,住培基地准入和再认证机制不完善,持续职业发展教育亟待规范。通过对国际上主要国家发展全科医生经验的回顾研究,建议我国应当切实提升全科医生待遇;以“岗位胜任力”为导向,建立完善的全科医生培训过程考核体系;统一全科医生住培基地准入条件,建立常态化基地评估认证机制;设置全科持续职业发展教育基地。
XU Aijun, TIAN Yuke, DUAN Shiming
《医学前沿(英文)》 2007年 第1卷 第2期 页码 207-210 doi: 10.1007/s11684-007-0039-x
《化学科学与工程前沿(英文)》 2022年 第16卷 第12期 页码 1743-1750 doi: 10.1007/s11705-022-2184-9
关键词: standard enthalpy of formation polycyclic aromatic hydrocarbons connectivity based hierarchy high-precision calculation
孟柳,延建林,董景辰,韦莎,李瑞琪,臧冀原,周源
《中国工程科学》 2018年 第20卷 第4期 页码 23-28 doi: 10.15302/J-SSCAE-2018.04.005
智能制造是一个不断演进的大系统,涵盖了产品、制造、服务全生命周期中所涉及的理论、方法、技术和应用。面对智能制造不断涌现的新技术、新理念、新模式,迫切需要总结提出智能制造系统架构,以更好地指导智能制造落地实施。本文从价值维、技术维和组织维三个维度构建了中国智能制造总体架构,并分别与美国、德国、日本智能制造相关系统架构做了横向比较。智能制造总体架构的技术维反映了智能制造以两化融合为主线,价值维体现了智能制造的主体是制造活动,组织维强调了智能制造要以人为本。
标题 作者 时间 类型 操作
Numerical investigation of circle defining curve for two-dimensional problem with general boundaries
Chung Nguyen VAN
期刊论文
coated on endotracheal tube with or without epidural lidocaine reduces isoflurane requirement during general
null
期刊论文
The next step of community health construction: Training general practitioners and implementing health
Kan ZHANG MM, Wei DONG MM, Ying-Yao CHEN MD,
期刊论文
General modeling and optimization technique for real-world earth observation satellite scheduling
期刊论文
Feasible workspace regions for general two-revolute manipulator
Conghui LIANG, Marco CECCARELLI
期刊论文
pulse oximetry is more accurate and detects hypoxemia earlier than conventional pulse oximetry during general
null
期刊论文
Effects of intracerebroventricular NMDA and non-NMDA receptor agonists or antagonists on general anesthesia
XU Aijun, TIAN Yuke, DUAN Shiming
期刊论文
High-precision standard enthalpy of formation for polycyclic aromatic hydrocarbons predicting from general
期刊论文