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Current hepatitis B treatment guidelines and future research directions
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《医学前沿(英文)》 2014年 第8卷 第2期 页码 145-157 doi: 10.1007/s11684-014-0335-1
Hepatitis B virus (HBV) infection causes a tremendous clinical burden across the world with more than half a million people dying annually from HBV related disease. Significant advances have been made in HBV treatment in the past decade and several guidelines have been published by professional societies and expert panels. Although these recommendations have been valuable to help optimize HBV treatment, there is discordance in treatment criteria and many patients infected with HBV may fall outside of these recommendations. This paper systematically reviews the natural history of the disease and compares and contrasts the recommendations for initiation of treatment from the various societies. There is also discussion of special groups that require particular consideration and some of the open research questions and future research directions within the field.
关键词: chronic hepatitis B HBV treatment guidelines APASL guidelines EASL guidelines AASLD guidelines
Review of recent guidelines for the management of severe sepsis and septic shock
Jin-Nong ZHANG MD, Bo PENG BA, Jamile WOODS MD, Wei PENG MD, PhD,
《医学前沿(英文)》 2010年 第4卷 第1期 页码 54-58 doi: 10.1007/s11684-010-0008-7
The imperative need to develop guidelines to manage human versus machine intelligence
Donald KENNEDY, Simon P. PHILBIN
《工程管理前沿(英文)》 2018年 第5卷 第2期 页码 182-194 doi: 10.15302/J-FEM-2018085
关键词: human intelligence & machine intelligence HI-MI decision-making artificial intelligence
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《医学前沿(英文)》 2012年 第6卷 第3期 页码 332-337 doi: 10.1007/s11684-012-0212-8
Bedside limited echocardiography, or focused cardiac ultrasound, continues to gain popularity in many emergency rooms, intensive care units, and operating rooms as a rapid method of assessing unstable patients. Effective monitoring of cardiovascular function in conditions like cardiac arrest or near-arrest is the crucial step to guide successful resuscitative efforts. Transesophageal echocardiography (TEE) has emerged as one of the preferred cardiac diagnostic and monitoring modalities in the intraoperative setting due to the fact that it is less invasive than many other monitors, is immediately accessible, and allows for continuous real-time monitoring of cardiac function. However, the minimum training requirements needed for the anesthesia provider to obtain the competency, knowledge, and skills for basic certification in perioperative TEE far exceed those developed for other medical specialties. We believe there is an urgent need to develop (1) practical guidelines for emergent perioperative TEE use for anesthesiologists and (2) a requisite educational curriculum to teach the basic skills necessary to aid in the diagnosis and treatment of cardiac arrest or near-arrest scenarios. The measures elucidated in this report summarize the efforts of the Department of Anesthesiology at the University of Florida in establishing the necessary steps to make this process not only practical, but accessible to all trainees. We hope that these collective efforts will provide more trainees the confidence in utilizing TEE to aid in establishing a diagnosis in critical situations.
关键词: transesophageal echocardiography curriculum competency training hemodynamic instability
Guidelines for navigation-assisted spine surgery
Wei Tian, Bo Liu, Da He, Yajun Liu, Xiaoguang Han, Jingwei Zhao, Mingxing International Society for Computer Assisted Orthopaedic Surgery
《医学前沿(英文)》 2020年 第14卷 第4期 页码 518-527 doi: 10.1007/s11684-020-0775-8
Peng ZHENG, Xuan YAO, Wei ZHENG
《能源前沿(英文)》 2013年 第7卷 第1期 页码 127-132 doi: 10.1007/s11708-012-0225-7
关键词: urea hydrolyser ammonia selective catalytic reduction (SCR)
Xuan LIU,Zifu LI,Eric BOSC,Heinz-Peter MANG
《环境科学与工程前沿(英文)》 2014年 第8卷 第5期 页码 710-718 doi: 10.1007/s11783-013-0592-2
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《医学前沿(英文)》 2015年 第9卷 第1期 页码 123-128 doi: 10.1007/s11684-014-0366-7
Guidelines for the intraoperative transesophageal echocardiography (TEE) examination have defined a detailed standard for medical professionals, particularly anesthesiologists, on how a TEE exam should proceed. Over the years, TEE has gained substantial popularity and emerged as a preferred monitoring modality to aid in perioperative management and decision making during hemodynamic instability situations or critical care settings. TEE training pathways and practice guidelines have been well established in western countries and many regions of the world. However, TEE training and practice information for anesthesiologists are lacking in China. As innovative technologies develop, other educational models have emerged to aid in obtaining competency in basic TEE exam. Hence, establishing a consensus on the ideal TEE training approach for anesthesiologists in China is urgently needed. Developing an effective curriculum that can be incorporated into an anesthesiology resident’s overall training is also necessary to provide knowledge and skills toward competency in basic TEE exam. With evolving medical system reforms and increasing demands for intraoperative hemodynamic monitoring to accommodate surgical innovations, anesthesiology professionals are increasingly obliged to perform intraoperative TEE exams in their current and future practices. To overcome obstacles and achieve significant progress in using the TEE modality to help in intraoperative management and surgical decision making, publishing basic TEE training guidelines for China’s anesthesiologists is an important endeavor.
关键词: transesophageal echocardiography guidelines training competency
The regulatory sciences for stem cell-based medicinal products
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《医学前沿(英文)》 2014年 第8卷 第2期 页码 190-200 doi: 10.1007/s11684-014-0323-5
Over the past few years, several new achievements have been made from stem cell studies, many of which have moved up from preclinical stages to early, or from early to middle or late, stages thanks to relatively safe profile and preliminary evidence of effectiveness. Moreover, some stem cell-based products have been approved for marketing by different national regulatory authorities. However, many critical issues associated mainly with incomplete understanding of stem cell biology and the relevant risk factors, and lack of effective regulations still exist and need to be urgently addressed, especially in countries where establishment of appropriate regulatory system just commenced. More relevantly, the stem cell regulatory sciences need to be established or improved to more effectively evaluate quality, safety and efficacy of stem cell products, and for building up the appropriate regulatory framework. In this review, we summarize some new achievements in stem cell studies, especially the preclinical and clinical studies, the existing regulations, and the associated challenges, and we then propose some considerations for improving stem cell regulatory sciences with a goal of promoting the steadfast growth of the well-regulated stem cell therapies abreast of evolvement of stem cell sciences and technologies.
关键词: stem cell-based medicinal products (SCMPs) stem cell therapy (SCT) safety effectiveness standards guidelines regulatory science
方东平 ,李文琪 ,张恒力 ,刘合
《中国工程科学》 2022年 第24卷 第5期 页码 187-196 doi: 10.15302/J-SSCAE-2022.05.023
标题 作者 时间 类型 操作
Review of recent guidelines for the management of severe sepsis and septic shock
Jin-Nong ZHANG MD, Bo PENG BA, Jamile WOODS MD, Wei PENG MD, PhD,
期刊论文
The imperative need to develop guidelines to manage human versus machine intelligence
Donald KENNEDY, Simon P. PHILBIN
期刊论文
Emergent limited perioperative transesophageal echocardiography: should new guidelines exist for limited
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期刊论文
Guidelines for navigation-assisted spine surgery
Wei Tian, Bo Liu, Da He, Yajun Liu, Xiaoguang Han, Jingwei Zhao, Mingxing International Society for Computer Assisted Orthopaedic Surgery
期刊论文
Design guidelines for urea hydrolysers for ammonia demand of the SCR DENOX project in coal-fired power
Peng ZHENG, Xuan YAO, Wei ZHENG
期刊论文
dry-toilet collected matters from suburban areas of Ulaanbaatar, Mongolia, using biosolids quality guidelines
Xuan LIU,Zifu LI,Eric BOSC,Heinz-Peter MANG
期刊论文
Essential training steps to achieving competency in the basic intraoperative transesophageal echocardiography examination for Chinese anesthesiologists
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期刊论文