2012, Volume 14, Issue 7
Strategic Study of CAE >> 2012, Volume 14, Issue 7
Clinical response with functional image during radiotherapy of esophageal squamous cell carcinoma
Radiation Therapy of Shandong Tumor Hospital, Jinan 250117, China
Next Previous
Abstract
18F-FLT uptake can be used to monitor the biological response of esophageal SCC and normal tissue to RT. Increased uptake of 18F-FLT following treatment interruptions may reflect accelerated repopulation. 18F-FLT PET may have advantages compared to 18F-FDG PET in differentiating inflammation from tumor. 18F-FLT PET may help oncologists predict treatment response as early as one week after the beginning of treatment and estimate clonogenic repopulation during RT. 18F-FETNIM PET can depict hypoxia in esophageal SCC. Prior to CCRT, tumor hypoxia demonstrates spatial variability in different days, though overall 18F-FETNIM uptake remains similar. Baseline SUVmax may be predictive of treatment response.
京公网安备 11010502051620号
