2012, Volume 14, Issue 8
Strategic Study of CAE >> 2012, Volume 14, Issue 8
Preliminary characterization of radiation fields of IHNI-1 for BNCT
1. China Institute of Atomic Energy, Beijing 1024133, China;
2. Beijing Capture Technology Co. Ltd., Beijing 102413, China
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Abstract
The characteristic parameters of the neutron radiation fields produced by an in-hospital neutron irradiatior for boron neutron capture therapy(BNCT), such as neutron energy spectra, neutron flux density and neutron absorbed dose rate and their spatial distributions in free air, etc., were measured to verify the design effect. According to the traits of the irradiators, a measuring system composed of a multi-sphere spectrometer, a 235U fission ionization chamber, gold foils, a tissue equivalent proportional counter and thermoluminescent detectors was established. In order to improve the energy resolution in epithermal energy range and the ability to discriminate different neutron components, the Monte Carlo method was used for optimizing the detectors. The preliminary results show that the neutron flux densities of the irradiators achieve the expected levels.
Keywords
in-hospital neutron irradiatior for BNCT ; neutron enengy spectrum ; neutron flux density ; absorbed dose rate of neutron and γ ray
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References
[ 1 ] Locher G L. Biological effects and therapeutic possibilities of neu-trons [J]. American Journal of Roentgenology , 1936, 36:1-13.
[ 2 ] Auterinen I, Serén T, Anttila K, et al. Measurement of freeneutron spectra at eight BNCT facilities worldwide [J]. Applied Radiation and Isotopes, 2004, 61: 1021-1026. link1
[ 3 ] Elisabetta Nava, Stefano Agosteo, Maurizio Angelone, et al. Pre-liminary characterization of the epithermal beam at the TAPIRO re-actor [C]//Proceedings of the 13th International Conference on Neutron Capture Therapy. Florence, 2008:537 -540.
[ 4 ] Ueda H, Tanaka H, Maruhashi A, et al. Spectral evaluation of cy-clotron-based epithermal neutron irradiation field for BNCT using Bonner Sphere [C]//Proceedings of 14th Intemnational Congress on Neutron Capture Therapy. Buenos Aires, Argentina, 2010:459 -462.
[ 5 ] Errico F d´, Ciolini R, Fulvio A Di, et al. Angle-and energy-differential neutron spectrometry for the SPES BNCT facility [J].Applied Radiation and Isotopes, 2009, 67 (7-8 suppl. ): 141-144 link1
[ 6 ] Yasuhiro Unno, Shunsuke Yonai, Mamoru Baba, et al. Bench-mark experiments on neutron moderator assembly for cyclotron-based boron neutron capture therapy [C]//Proceedings of ICNCT -1212th International Congress on Neutron Capture Therapy. Takamat-su, Kagawa, Japan, 2006:331-334.
[ 7 ] Kononov V N, Bokhovko M V, Kononov O E, et al. The time-of-flight epithermal neutron spectrum measurement from accelerator based BNCT facility [C]//Proceedings of ICNCT-12 12th Inter-national Congress on Neutron Capture Therapy. TakamatsFu, Ka-gawa, Japan, 2006:368-370.
[ 8 ] Hamidi S. Scott M C. BNCT neutron beam characterization usinga resonance absorption filter method[J]. Nuclear Instruments and Methods in Physics Research A, 2002. 476:99-105. link1
[ 9 ] Antoaneta Roca, Yuan-Hao Liu, Cecile Wojnecki, et al. A pre-liminary inter-centre comparison study for photon, thermal neutron and epithermal neutron responses of two pairs of ionization cham-bers used for BNCT [J]. Applied Radiation and Isotopes, 2009,67(7-8 suppl. ):134 -136 link1
[10] Fuji T., Tanaka H, Maruhashi A, et al. Study on optimization of multi ionization-chamber system for BNCT C1//Proceedings of14th International Congress on Neutron Capture Therapy. Buenos Aires, Argentina, 2010:177-180.
[11] Almaviva S, Macro Marinelli, Milani E, et al. Thermal neutron dosimeter by synthetic single crystal diamond devices [J]. Applied Radiation and Isotopes, 2009, 67 (7-8 suppl.): 183-185. link1
[12] Marek M. Viererbl L.. Spatial characterization of BNCT beams[J]. Applied Radiation and Isotopes, 2004, 61 :1051-1055. link1
[13] Ming-Chen Hsiao, Wei-Lin Chen, Pi-En Tsai, et al. A prelimi-nary study on using the radiochromic film for 2D beam profile QC/QA at the THOR BNCT facility [C1//Proceedings of 14th International Congress on Neutron Capture Therapy. Buenos Aires, Argentina, 2010:203 -206.
[14] Gambarini G. Klamert V. Agosteo S, et al. Study of a methodl based on TLD detectors for in-phantom dosimetry in BNCT[J]Radiation Protection Dosimetry, 2004, 110 (1-4): 631-636. link1
[15] Endo S, Onizuka Y, Ishikawa M, et al. Microdosimetry of neu-tron field for boron neutron capture therapy at Kyoto University reactor[J]. Radiation Protection Dosimetry, 2004, 110(1-4):641-644 link1
[16] Fang-Yuh Hsu, Hsiu-Wen Hsiao, Chuan-Jong Tung, et al. Mi-crodosimetry study of THOR BNCT beam using tissue equinalent proportional counter[J]. Applied Radiation and Isotopes, 2009,67 (7-8 suppl. ) :175 -178. link1
[17] Bartolotta A. M C D´ Oca, B Lo Giudice, et al. Combined TL.and 1 B-Alanine ESR dosimetry for BNCT [J]. Radiation Pro-tection Dosimetry, 2004, 110(1-4):627-630. link1
[18] Baetesaghi G, Burian J, Gambarini G, et al. Evaluation of all dose components in the LVR-15 reactor epithermal neutron beam using Fricke gel dosimeter layers [J]. Applied Radiation and Isotopes , 2009, 67 (7-8 suppl. ):199-201. link1
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