2015, Volume 17, Issue 6
Strategic Study of CAE >> 2015, Volume 17, Issue 6
The relationship between maternal environmental factors and fetus congenital heart disease
1. Jiangsu Institute of Planned Parenthood Research, Nanjing 210036, China;
2. School of Public Health Nanjing Medical University, Nanjing 210029, China
Next Previous
Abstract
Objective：To study the relationship between maternal risk factors and fetus congenital heart disease in Jiangsu province for exploration of effective prevention strategy．Methods：By 1:1.4 case-control study, 373 valid questionnaires were collected from July 2012 to December 2013 and the environmental risk factors of congenital heart disease were analyzed．Results：It showed that the risks such as congenital heart disease family history,history of miscarriage,adverse pregnancy history,history of pesticide exposure during pregnancy,early pregnancy sickness, early pregnancy medication, pregnancy fetal abnormalities,were the most important determinants associated with CHD of children(P<0.05).Conclusions：It is particularly important of maternal health, reducing exposure to risk factors and periodic prenatal for reducing the risk of congenital heart disease.
Keywords
References
[ 1 ] 施 淼，综 述，洪新如，等. 先天性心脏病病因学的研究进 展[J]. 国际妇产科学杂志，2012，39（2）：183-186. link1
[ 2 ] 高 燕，黄国英. 先天性心脏病因及流行病学研究进展[J]. 中国 循证儿科杂志，2008，3（3）：213-222. link1
[ 3 ] 刘 凤，陶芳标，严双琴，等. 父母环境因素暴露于胎儿闲心疾 病因关系探索[J]. 临床儿科杂志，2009，27（5）：424.
[ 4 ] Hoffman J I，Kaplan S.The incidence of congenital heart disease [J].Journal of the American College of Cardiology，2002，39 （12）：1890-1900. link1
[ 5 ] 曹泽毅. 中华妇产科学[M]. 北京：人民卫生出版社，2007.
[ 6 ] Carmichael S L，Shaw G M. Maternal life event stress and congenital anomalies[J]. Epidemiology，2000，1（l 1）：30-35. link1
[ 7 ] 胡 卉，刘 珍，李小洪，等. 孕早期非遗传因素与先天性心脏 病的病例对照研究[J]. 中国妇幼保健，2014，29：3420-3424. link1
[ 8 ] Oster M E，Riehle-Colarusso T，Alverson C J，et a1. Associations between maternal fever and influenza and congenital heart defects [J].The Journal of Pediatrics，2011，158（6）：990-995. link1
[ 9 ] 陆铭娜. 先天性心脏病非遗传性病因的研究进展[J]. 国际妇产 科学杂志，2009，36（4）：320-323. link1
京公网安备 11010502051620号
