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Fabrication and in vivo evaluation of Ti6Al4V implants with controlled porous structure and complex shape

Xiang LI, Yun LUO, Chengtao WANG, Wenguang ZHANG, Yuanchao LI

Frontiers of Mechanical Engineering 2012, Volume 7, Issue 1, Pages 66-71 doi: 10.1007/s11465-012-0302-y

Abstract: Standard implants and a custom implant coupled with porous sections were designed and fabricated to validategrew from the calvarial margins toward the center of the bone defect and was in close contact with implant

Keywords： electron beam melting process implant porous structure bone ingrowth

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A Review of 3D Printing Technology for Medical Applications Review

Qian Yan,Hanhua Dong,Jin Su,Jianhua Han,Bo Song,Qingsong Wei, Yusheng Shi

Engineering 2018, Volume 4, Issue 5, Pages 729-742 doi: 10.1016/j.eng.2018.07.021

Abstract:

Donor shortages for organ transplantations are a major clinical challenge worldwide. Potential risks that are inevitably encountered with traditional methods include complications, secondary injuries, and limited source donors. Three-dimensional (3D) printing technology holds the potential to solve these limitations; it can be used to rapidly manufacture personalized tissue engineering scaffolds, repair tissue defects in situ with cells, and even directly print tissue and organs. Such printed implants and organs not only perfectly match the patient’s damaged tissue, but can also have engineered material microstructures and cell arrangements to promote cell growth and differentiation. Thus, such implants allow the desired tissue repair to be achieved, and could eventually solve the donor-shortage problem. This review summarizes relevant studies and recent progress on four levels, introduces different types of biomedical materials, and discusses existing problems and development issues with 3D printing that are related to materials and to the construction of extracellular matrix in vitro for medical applications.

Keywords： 3D printing Implant Scaffold Biomedical material

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A Systematic Approach for Making 3D-Printed Patient-Specific Implants for Craniomaxillofacial Reconstruction Article

Ruxu Du, Yu-Xiong Su, Yu Yan, Wing Shan Choi, Wei-Fa Yang, Chunyu Zhang, Xianshuai Chen, Justin Paul Curtin, Jianglin Ouyang, Bitao Zhang

Engineering 2020, Volume 6, Issue 11, Pages 1291-1301 doi: 10.1016/j.eng.2020.02.019

Abstract: During surgery, the implant must be bended manually to match the anatomy of the individual bones.resulting in fatigue under masticatory loading in vivo and causing various complications such as implantpost-processing treatments (i.e., heat and surface treatments) to ensure the quality and performance of the implantThird, the operation begins after the final checking of the implant and sterilization.Moreover, the presented approach helps to ensure implant quality.

Keywords： Patient-specific implant Craniomaxillofacial reconstruction 3D printing Surgery