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Engineered Vasculature for Organ-on-a-Chip Systems Review

Abdellah Aazmi, Hongzhao Zhou, Yuting Li, Mengfei Yu, Xiaobin Xu, Yutong Wu, Liang Ma, Bin Zhang, Huayong Yang

Engineering 2022, Volume 9, Issue 2,   Pages 131-147 doi: 10.1016/j.eng.2021.06.020

Abstract:

Organ-on-a-chip technology, a promising three-dimensional (3D) dynamic culture method, ensures accurateThus, it is essential to integrate the circulatory system into an organ-on-a-chip to recreate tissueand organ microenvironments and physiological functions.This review discusses the synergy between the vasculature and the emerging organ-on-a-chip technologyIn addition, we review the different steps of a vascularized organ-on-a-chip fabrication process, including

Keywords： Organ-on-a-chip     Vasculature     Bioprinting     Tumor-on-a-chip    

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Piezoelectric pump with flexible venous valves for active cell transmission

Frontiers of Mechanical Engineering 2022, Volume 17, Issue 4, doi: 10.1007/s11465-022-0712-4

Abstract: The development of organ-on-a-chip systems demands high requirements for adequate micro-pump performanceThe proposed pump can help to construct the circulating organ-on-a-chip system, and the simple structuredesign of the micro-pump and providing a reference for the further study of active cell transport in organ-on-a-chip

Keywords： venous valve     flexible venous valve     cell transmission     organ-on-a-chip system     piezoelectric device    

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Engineering Solutions for Representative Models of the Gastrointestinal Human-Microbe Interface

Marc Mac Giolla Eain, Joanna Baginska, Kacy Greenhalgh, Joëlle V. Fritz, Frederic Zenhausern, Paul Wilmes

Engineering 2017, Volume 3, Issue 1,   Pages 60-65 doi: 10.1016/J.ENG.2017.01.011

Abstract:

Host-microbe interactions at the gastrointestinal interface have emerged as a key component in the governance of human health and disease. Advances in micro-physiological systems are providing researchers with unprecedented access and insights into this complex relationship. These systems combine the benefits of microengineering, microfluidics, and cell culture in a bid to recreate the environmental conditions prevalent in the human gut. Here we present the human-microbial cross talk (HuMiX) platform, one such system that leverages this multidisciplinary approach to provide a representative in vitro model of the human gastrointestinal interface. HuMiX presents a novel and robust means to study the molecular interactions at the host-microbe interface. We summarize our proof-of-concept results obtained using the platform and highlight its potential to greatly enhance our understanding of host-microbe interactions with a potential to greatly impact the pharmaceutical, food, nutrition, and healthcare industries in the future. A number of key questions and challenges facing these technologies are also discussed.

Keywords： Microbiome     Microfluidics     Organ-on-a-chip     HuMiX    

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Detection of solder bump defects on a flip chip using vibration analysis

Junchao LIU, Tielin SHI, Qi XIA, Guanglan LIAO

Frontiers of Mechanical Engineering 2012, Volume 7, Issue 1,   Pages 29-37 doi: 10.1007/s11465-012-0314-7

Abstract: Solder bump defects on flip chips are difficult to detect, because the solder bumps are obscured by the chipvibration analysis is presented for detecting missing solder bumps, which is a typical defect in flip chipThe flip chip analytical model is revised by considering the influence of spring mass on mechanical energyThis revised model is then applied to estimate the flip chip resonance frequencies.Therefore, it may provide a guide for the improvement and innovation of the flip chip on-line inspection

Keywords： flip chip     defect detection     ultrasonic excitation     vibration analysis    

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Dymola-based multi-parameters integrated optimization for high speed transfer system of LED chip sorter

Jie OUYANG, Bin LI, Shihua GONG

Frontiers of Mechanical Engineering 2013, Volume 8, Issue 2,   Pages 118-126 doi: 10.1007/s11465-013-0253-y

Abstract:

To enhance the performance of high speed transfer system of LED chip sorting equipment, its control

Keywords： LED chip sorter     multi-domain modeling and simulation     parameter optimization     modelica language    

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Single-chip 3D electric field microsensor

Biyun LING, Yu WANG, Chunrong PENG, Bing LI, Zhaozhi CHU, Bin LI, Shanhong XIA

Frontiers of Mechanical Engineering 2017, Volume 12, Issue 4,   Pages 581-590 doi: 10.1007/s11465-017-0454-x

Abstract:

This paper presents a single-chip 3D electric field microsensor, in which a sensing element is set

Keywords： electric field microsensor     three-dimensional     single-chip     in-plane rotation    

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Development of an electrorheological chip and conducting polymer based sensor

Xianzhou ZHANG, Weihua LI, Weijia WEN, Yanzhe WU, Gordon WALLACE,

Frontiers of Mechanical Engineering 2009, Volume 4, Issue 4,   Pages 472-472 doi: 10.1007/s11465-009-0077-y

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SIMULATION OF O-BLOWN CO-GASIFICATION OF WOOD CHIP AND POTATO PEEL FOR PRODUCING SYNGAS

Frontiers of Agricultural Science and Engineering 2023, Volume 10, Issue 3,   Pages 448-457 doi: 10.15302/J-FASE-2023490

Abstract:

● Low-value biowaste including wood chip and potato peel was valorized

Keywords： Aspen Plus     co-gasification     potato peel     syngas     simulation     waste reduction     wood chip    

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3D finite element prediction of chip flow, burr formation, and cutting forces in micro end-milling of

A. DAVOUDINEJAD, P. PARENTI, M. ANNONI

Frontiers of Mechanical Engineering 2017, Volume 12, Issue 2,   Pages 203-214 doi: 10.1007/s11465-017-0421-6

Abstract: simulations were performed under different cutting conditions to obtain realistic numerical predictions of chipnotable advantages, such as capability to easily handle any type of tool geometry and any side effect on chipThe proposed 3D FE model considers the effects of mill helix angle and cutting edge radius on the chip

Keywords： 3D finite element modeling     micro end-milling     cutting force     chip formation     burr formation    

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Three-Dimensional Chip Imaging

Marcus Woo

Engineering 2020, Volume 6, Issue 5,   Pages 485-486 doi: 10.1016/j.eng.2020.03.009

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Development of electrorheological chip and conducting polymer-based sensor

Xianzhou ZHANG, Weihua LI, Weijia WEN, Yanzhe WU, Gordon WALLACE,

Frontiers of Mechanical Engineering 2009, Volume 4, Issue 4,   Pages 393-396 doi: 10.1007/s11465-009-0043-8

Abstract: The developed ER chip worked as an actuator, and it was driven by different voltages and control frequenciesmonotonically when the frequency increases, owing to the time delay in the pressure buildup in the ER chip

Keywords： electrorheological (ER) fluids     conducting polymer (CP)     polydimethylsioxane (PDMS)     driving frequency     amplitude     bubble counter    

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Machine Learning Produces Superhuman Chip Designs

Robert Pollie,

Engineering 2022, Volume 10, Issue 3,   Pages 7-9 doi: 10.1016/j.eng.2022.01.006

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A literature review of perishable medical resource management

Frontiers of Engineering Management   Pages 710-726 doi: 10.1007/s42524-023-0278-9

Abstract: In recent decades, healthcare providers have faced mounting pressure to effectively manage highly perishable and limited medical resources. This article offers a comprehensive review of supply chain management pertaining to such resources, which include transplantable organs and healthcare products. The review encompasses 93 publications from 1990 to 2022, illustrating a discernible upward trajectory in annual publications. The surveyed literature is categorized into three levels: Strategic, tactical, and operational. Key problem attributes and methodologies are analyzed through the assessment of pertinent publications for each problem level. Furthermore, research on service innovation, decision analytics, and supply chain resilience elucidates potential areas for future research.

Keywords： perishable medical resources     organ transplant     healthcare products     decision analytics     operations management    

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Development of Microfabrication Techniques for Production of Analysis Chip

Wei Shoushui,Zhang Yulin,Cui Dafu

Strategic Study of CAE 2004, Volume 6, Issue 10,   Pages 90-94

Abstract:

Fabrication of micro-channels is a key technique for production of analysis chip.Some available methods of microfabrication for production of analysis chip were proposed.

Keywords： analysis chip     microfabrication     μ-TAS    

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Emerging roles of podoplanin in vascular development and homeostasis

Yanfang Pan,Lijun Xia

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 421-430 doi: 10.1007/s11684-015-0424-9

Abstract: review provides a comprehensive overview of the roles of PDPN in vascular development and lymphoid organ

Keywords： podoplanin     CLEC-2     Prox1     O-glycosylation     lymphatic vascular development and maintenance     lymphoid organ    

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Title Author Date Type Operation

Engineered Vasculature for Organ-on-a-Chip Systems

Abdellah Aazmi, Hongzhao Zhou, Yuting Li, Mengfei Yu, Xiaobin Xu, Yutong Wu, Liang Ma, Bin Zhang, Huayong Yang

Journal Article

Piezoelectric pump with flexible venous valves for active cell transmission

Journal Article

Engineering Solutions for Representative Models of the Gastrointestinal Human-Microbe Interface

Marc Mac Giolla Eain, Joanna Baginska, Kacy Greenhalgh, Joëlle V. Fritz, Frederic Zenhausern, Paul Wilmes

Journal Article

Detection of solder bump defects on a flip chip using vibration analysis

Junchao LIU, Tielin SHI, Qi XIA, Guanglan LIAO

Journal Article

Dymola-based multi-parameters integrated optimization for high speed transfer system of LED chip sorter

Jie OUYANG, Bin LI, Shihua GONG

Journal Article

Single-chip 3D electric field microsensor

Biyun LING, Yu WANG, Chunrong PENG, Bing LI, Zhaozhi CHU, Bin LI, Shanhong XIA

Journal Article

Development of an electrorheological chip and conducting polymer based sensor

Xianzhou ZHANG, Weihua LI, Weijia WEN, Yanzhe WU, Gordon WALLACE,

Journal Article

SIMULATION OF O-BLOWN CO-GASIFICATION OF WOOD CHIP AND POTATO PEEL FOR PRODUCING SYNGAS

Journal Article

3D finite element prediction of chip flow, burr formation, and cutting forces in micro end-milling of

A. DAVOUDINEJAD, P. PARENTI, M. ANNONI

Journal Article

Three-Dimensional Chip Imaging

Marcus Woo

Journal Article

Development of electrorheological chip and conducting polymer-based sensor

Xianzhou ZHANG, Weihua LI, Weijia WEN, Yanzhe WU, Gordon WALLACE,

Journal Article

Machine Learning Produces Superhuman Chip Designs

Robert Pollie,

Journal Article

A literature review of perishable medical resource management

Journal Article

Development of Microfabrication Techniques for Production of Analysis Chip

Wei Shoushui,Zhang Yulin,Cui Dafu

Journal Article

Emerging roles of podoplanin in vascular development and homeostasis

Yanfang Pan,Lijun Xia

Journal Article