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Single-Molecule Methods for Characterizing Different DNA Higher-Order Structures Review

Yonglin Liu, Tianyuan Bian, Yan Liu, Zhimin Li, Yufeng Pei, Jie Song

Engineering 2023, Volume 24, Issue 5,   Pages 277-292 doi: 10.1016/j.eng.2022.10.009

Abstract: Single-molecule methods are powerful tools for observing the behavior of individual molecules and probingIn this review, we introduce single-molecule methods, including single-molecule detection and manipulationmethods, and discuss how these methods can be conducive to measuring the molecular properties of singleWe conclude by providing a new perspective on the combination of DNA nanotechnology and single-moleculemethods to understand the biophysical properties of DNA and other bio-matter and soft matter.

Keywords： Single-molecule methods     DNA structure     Mechanical properties     Conformational transitions    

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Integrated virtual-design methods for forecasting radiated noise of single cylinder diesel block

GUO Lei, HAO Zhiyong, XU Hongmei, LIU Lianyun

Frontiers in Energy 2008, Volume 2, Issue 4,   Pages 416-421 doi: 10.1007/s11708-008-0097-z

Abstract: The two cycle dynamical results, such as the bearing load, the piston thrust, and the load spatial distribution etc., were obtained by hybrid dynamical simulation of the flexible assembly of the block and crank-train. The finite element model of the block was validated by modal test. The frequency response of the block was calculated using the finite element method (FEM). Finally, the radiated noise such as sound power level and efficiency in the out sound field were obtained using the direct boundary element method (BEM).

Keywords： bearing     dynamical     frequency response     dynamical simulation     hybrid dynamical    

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A wind tunnel study on control methods for cable dry-galloping

Hung D. VO,Hiroshi KATSUCHI,Hitoshi YAMADA,Mayuko NISHIO

Frontiers of Structural and Civil Engineering 2016, Volume 10, Issue 1,   Pages 72-80 doi: 10.1007/s11709-015-0309-7

Abstract: Furthermore, single spiral wire, double spiral wire and circular ring were found to have high effectiveness

Keywords： dry-galloping     wind-relative angle     single spiral wire     double spiral wire     circular rings    

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Discovery of small molecule degraders for modulating cell cycle

Frontiers of Medicine 2023, Volume 17, Issue 5,   Pages 823-854 doi: 10.1007/s11684-023-1027-5

Abstract: Additionally, possible methods are discussed for the development of degraders for CDK members that still

Keywords： PROTAC     molecular glue     degrader     cell cycle     CDK     cyclin    

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Temperature and structural responses of a single-section utility tunnel throughout fire exposure

Yanmin YANG; Ying XIONG; Yongqing LI; Xiangkun MENG; Peng WANG; Tianyuan CAI

Frontiers of Structural and Civil Engineering 2022, Volume 16, Issue 10,   Pages 1351-1364 doi: 10.1007/s11709-022-0857-6

Abstract: In this study, fire tests of four single-section scaled-down utility tunnels were conducted.tunnel throughout the fire exposure, the effects on the fire behavior of two different construction methods

Keywords： full lightweight concrete     construction methods     temperature response     structural response     fire test    

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Near-infrared benzodiazoles as small molecule environmentally-sensitive fluorophores

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 128-135 doi: 10.1007/s11705-021-2080-8

Abstract: The development of fluorophores emitting in the near-infrared spectral window has gained increased attention given their suitable features for biological imaging. In this work, we have optimised a general and straightforward synthetic approach to prepare a small library of near-infrared-emitting C-bridged nitrobenzodiazoles using commercial precursors. C-bridged benzodiazoles have low molecular weight and neutral character as important features that are not common in most near-infrared dyes. We have investigated their fluorescence response in the presence of a wide array of 60 different biomolecules and identified compound 3i as a potential chemosensor to discriminate between Fe2+ and Fe3+ ions in aqueous media.

Keywords： fluorescence     probes     iron     screening     library    

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Standardization in testing methods for SOFC single cells

Tu Hengyong

Strategic Study of CAE 2013, Volume 15, Issue 2,   Pages 33-38

Abstract: of solid oxide fuel cell (SOFC) reveal complex relationship between materials, fabrication methodsStandardization in testing methods contributes to building of effective and sound connections betweenthe system construction, procedure formulation and standardized reporting of results for SOFC single

Keywords： solid oxide fuel cell     performance testing     testing routines     standardization    

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Recent advances of small-molecule fluorescent probes for detecting biological hydrogen sulfide

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 34-63 doi: 10.1007/s11705-021-2050-1

Abstract: It was recently revealed that H2S is also an endogenous signaling molecule that has important

Keywords： hydrogen sulfide     fluorescent probe     reducibility     nucleophilicity     copper sulfide precipitate     hydrogen polysulfides    

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A pseudocapacitive molecule-induced strategy to construct flexible high-performance asymmetric supercapacitors

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 9,   Pages 1208-1220 doi: 10.1007/s11705-023-2304-1

Abstract: we present an “advantage-complementary strategy” using sodium lignosulfonate as a pseudocapacitive molecule

Keywords： molecular synergy     pseudocapacitive lignosulfonate     flexible electronic devices     asymmetric supercapacitor     wide voltage windows    

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Genetic biosensors for small-molecule products: Design and applications in high-throughput screening

Qingzhuo Wang,Shuang-Yan Tang,Sheng Yang

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 1,   Pages 15-26 doi: 10.1007/s11705-017-1629-z

Abstract: Overproduction of small-molecule chemicals using engineered microbial cells has greatly reduced the productionSuch biosensors allow a high-throughput screening of the small-molecule products, and can be roughlyThis review summarizes the recent developments in the design and applications of biosensors for small-molecule

Keywords： biosensor     small molecule product     transcription factor     riboswitch     high-throughput screening    

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Calculation of collision frequency function for aerosol particles in free molecule regime in presence

Xiaowei LUO, Yannick BENICHOU, Suyuan YU

Frontiers in Energy 2013, Volume 7, Issue 4,   Pages 506-510 doi: 10.1007/s11708-013-0275-5

Abstract: The collision frequency function for aerosol particles has already been calculated for the free moleculecollision frequency in the case of particles much smaller than the mean free path of the gas (free molecule

Keywords： aerosol particles     collision frequency function     coagulation    

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Development of small-molecule viral inhibitors targeting various stages of the life cycle of emerging

Xiaohuan Wang, Peng Zou, Fan Wu, Lu Lu, Shibo Jiang

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 449-461 doi: 10.1007/s11684-017-0589-5

Abstract: In this review, we summarize and discuss the latest progress in the development of small-molecule viralWe also discuss some general strategies for developing small-molecule viral inhibitors.

Keywords： emerging and re-emerging viruses     small-molecule inhibitor     coronavirus     Ebola virus     Zika virus     life cycle    

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Small-molecule anti-COVID-19 drugs and a focus on China’s homegrown mindeudesivir (VV116)

Frontiers of Medicine 2023, Volume 17, Issue 6,   Pages 1068-1079 doi: 10.1007/s11684-023-1037-3

Abstract: So far, a few small-molecule antiviral drugs, including nirmatrelvir–ritonavir (Paxlovid), remdesivirregarding the pharmacological mechanism and therapeutic effects focusing on mindeudesivir and other small-molecule

Keywords： COVID-19     antiviral drugs     mindeudesivir    

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Design of nanocarriers for efficient cellular uptake and endosomal release of small molecule and nucleic

Vaibhav Mundra, Ram I. Mahato

Frontiers of Chemical Science and Engineering 2014, Volume 8, Issue 4,   Pages 387-404 doi: 10.1007/s11705-014-1457-3

Abstract: There are many challenges in developing efficient and target specific delivery systems of small molecule

Keywords： nanocarrier     cellular uptake     endosomal release     nucleic acid drug    

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The Research on Measurement of Drift in the Evaluation Conclusion of Single Method

Chen Guohong,Li Meijuan,Chen Yantai

Strategic Study of CAE 2004, Volume 6, Issue 3,   Pages 58-63

Abstract:

In this paper drifting nature in the evaluation conclusion of single method is investigated in orderThen, objects to be evaluated are generated by Matlab 6.1, and are evaluated by using different methodsThird, the compatibility of the comprehensive evaluation methods is discriminated.Finally, the average of the compatible methods is adopted as reference frame in order to measure drifting

Keywords： comprehensive evaluation methods     computer simulation experiment     measurement of drift    

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Title Author Date Type Operation

Single-Molecule Methods for Characterizing Different DNA Higher-Order Structures

Yonglin Liu, Tianyuan Bian, Yan Liu, Zhimin Li, Yufeng Pei, Jie Song

Journal Article

Integrated virtual-design methods for forecasting radiated noise of single cylinder diesel block

GUO Lei, HAO Zhiyong, XU Hongmei, LIU Lianyun

Journal Article

A wind tunnel study on control methods for cable dry-galloping

Hung D. VO,Hiroshi KATSUCHI,Hitoshi YAMADA,Mayuko NISHIO

Journal Article

Discovery of small molecule degraders for modulating cell cycle

Journal Article

Temperature and structural responses of a single-section utility tunnel throughout fire exposure

Yanmin YANG; Ying XIONG; Yongqing LI; Xiangkun MENG; Peng WANG; Tianyuan CAI

Journal Article

Near-infrared benzodiazoles as small molecule environmentally-sensitive fluorophores

Journal Article

Standardization in testing methods for SOFC single cells

Tu Hengyong

Journal Article

Recent advances of small-molecule fluorescent probes for detecting biological hydrogen sulfide

Journal Article

A pseudocapacitive molecule-induced strategy to construct flexible high-performance asymmetric supercapacitors

Journal Article

Genetic biosensors for small-molecule products: Design and applications in high-throughput screening

Qingzhuo Wang,Shuang-Yan Tang,Sheng Yang

Journal Article

Calculation of collision frequency function for aerosol particles in free molecule regime in presence

Xiaowei LUO, Yannick BENICHOU, Suyuan YU

Journal Article

Development of small-molecule viral inhibitors targeting various stages of the life cycle of emerging

Xiaohuan Wang, Peng Zou, Fan Wu, Lu Lu, Shibo Jiang

Journal Article

Small-molecule anti-COVID-19 drugs and a focus on China’s homegrown mindeudesivir (VV116)

Journal Article

Design of nanocarriers for efficient cellular uptake and endosomal release of small molecule and nucleic

Vaibhav Mundra, Ram I. Mahato

Journal Article

The Research on Measurement of Drift in the Evaluation Conclusion of Single Method

Chen Guohong,Li Meijuan,Chen Yantai

Journal Article