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Molecular engineering of dendrimer nanovectors for siRNA delivery and gene silencing

Yu Cao, Xiaoxuan Liu, Ling Peng

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 4, Pages 663-675 doi: 10.1007/s11705-017-1623-5

Abstract: However, the clinical translation of RNA therapeutics mediated by dendrimer delivery is hampered by thepresents a brief introduction to RNAi therapeutics, the obstacles to their delivery and the advantages of dendrimerhighlight our efforts in creating self-assembling amphiphilic dendrimers to construct supramolecular dendrimerThe advent of self-assembling supramolecular dendrimer nanovectors holds great promise and heralds anew era of dendrimer-mediated delivery of RNA therapeutics in biomedical applications.

Keywords： gene therapy RNAi therapeutics dendrimer nanovectors gene silencing

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LDL adsorbent with dendrimer PAMAM as spacer

YUAN Yi, WANG Yanming, YU Yaoting

Frontiers of Chemical Science and Engineering 2008, Volume 2, Issue 4, Pages 434-438 doi: 10.1007/s11705-008-0084-2

Abstract: To study the spacer effect of low density lipoprotein (LDL) adsorbent, we linked dendrimer polyamidoamine

Keywords： adsorption proportion adsorbent dendrimer polyamidoamine reiterative generation

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Applications of nanomaterials in water treatment and environmental remediation

Gholamreza GHASEMZADEH,Mahdiye MOMENPOUR,Fakhriye OMIDI,Mohammad R. HOSSEINI,Monireh AHANI,Abolfazl BARZEGARI

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 4, Pages 471-482 doi: 10.1007/s11783-014-0654-0

Abstract: Nanotechnology has revolutionized plethora of scientific and technological fields; environmental safety is no exception. One of the most promising and well-developed environmental applications of nanotechnology has been in water remediation and treatment where different nanomaterials can help purify water through different mechanisms including adsorption of heavy metals and other pollutants, removal and inactivation of pathogens and transformation of toxic materials into less toxic compounds. For this purpose, nanomaterials have been produced in different shapes, integrated into various composites and functionalized with active components. Nanomaterials have also been incorporated in nanostructured catalytic membranes which can in turn help enhance water treatment. In this article, we have provided a succinct review of the most common and popular nanomaterials (titania, carbon nanotubes (CNTs), zero-valent iron, dendrimers and silver nanomaterials) which are currently used in environmental remediation and particularly in water purification. The catalytic properties and functionalities of the mentioned materials have also been discussed.

Keywords： photocatalysis titania silver carbon nanotube zero-valent iron dendrimer