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Near-infrared fluorescent probe for fast track of cyclooxygenase-2 in Golgi apparatus in cancer cells

Bhaskar Gurram, Miao Li, Jiangli Fan, Jingyun Wang, Xiaojun Peng

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 1,   Pages 41-52 doi: 10.1007/s11705-019-1796-1

Abstract: Cyclooxygenase-2 (COX-2) has been used as an excellent traceable biomarker, and exists maximally in GolgiCelecoxib (CCB) is a selective inhibitor for COX-2, and has been used as one of non-steroidal anti-inflammatory) with CCB via a six-carbon linkage to form a fluorescence probe NB-C6-CCB for the detection of COX-2.CCB) and Native-PAGE analysis confirmed that NB-C6-CCB shows selective binding affinity towards COX-2different concentrations, indicating that the NB-C6-CCB is a precise or sensitive probe for the COX-2.

Keywords： cyclooxygenase-2     nile blue     CCB     Golgi apparatus     NIR imaging    

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Cyclooxygenase-2 gene-1195G/A genotype is associated with the risk of HBV-induced HCC: A case-control

Li-Feng LIU MD, PhD, Qiong CHEN MD, PhD, Ying CHANG MD, PhD, Ju-Sheng LIN MD, PhD, Jin-Liang ZHANG MM,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 90-95 doi: 10.1007/s11684-010-0021-x

Abstract: This study aimed to identify functional single nucleotide polymorphisms in the cyclooxygenase-2 gene

Keywords： cyclooxygenase-2 gene     single nucleotide polymorphisms     susceptibility     primary hepatocellular carcinoma    

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metastasis is related to the epithelial-mesenchymal transition and expressions of VEGF, MMP-9, and COX-2

Lihui WANG, Lianhong LI, Shen LV, Shujun FAN, Li ZHAN, Bo WANG, Zhong ZHANG

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 164-170 doi: 10.1007/s11684-009-0038-1

Abstract: N-cadherin (N-Cad), vascular endothelial cell growth factor (VEGF), matrix metalloproteinase-9 (MMP-9), cyclooxygenase-2-2 (COX-2), and CD34 were examined in 74 cases of breast cancer, including 39 cases with lymph node metastasisThe expressions of N-Cad, VEGF, MMP-9, and COX-2 in cases with lymph node metastasis were significantlyThere was a statistical difference in the expression of COX-2 protein between histological grade I andThis study indicates that EMT and expressions of VEGF, MMP-9 and COX-2, and MVD value are strongly correlated

Keywords： epithelial-mesenchymal transition     vascular endothelial cell growth factor     matrix metalloproteinase-9     cyclooxygenase-2-2     higher microvascular density     breast cancer    

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Efficacy and safety of perioperative parecoxib for acute postoperative pain treatment in children: a meta-analysis

Xueshan Bu,Lei Yang,Yunxia Zuo

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 496-507 doi: 10.1007/s11684-015-0414-y

Abstract: with children who received placebo treatment, those who received parecoxib demonstrated lower early (2Similarly, children who received parecoxib had lower early (2 h) and later (12 h) postoperative pain

Keywords： NSAID     cyclooxygenase 2 inhibitor     child     pain     postoperative     opioid     placebo    

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Improvement in the synthesis of 2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(Z)-methoxyiminoacetic acid 2-benzothiazolyl

GAO Shihao, SUN Chenghui, ZHAO Xinqi, GAO Changquan

Frontiers of Chemical Science and Engineering 2008, Volume 2, Issue 1,   Pages 80-84 doi: 10.1007/s11705-008-0017-0

Abstract: 2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(Z)-methoxyiminoacetic acid 2-benzothiazolyl thioester(III), an importantintermediate of the fourth generation cephalosporins, was efficiently synthesized by reacting 2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(Z)-methoxyiminoacetic acid (I) with 2,2′-dibenzothiazole disulfide (II) in

Keywords： 5-Amino-1     2     4-thiadiazol-3-yl     1     2-dichloroethane     important intermediate     2-benzothiazolyl thioester     temperature    

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Effect of TiO 2 loading on the activity of V/TiO 2 -Al 2 O 3 in the catalytic oxidehydrogenation of ethylbenzene

Xiaohong LI, Wenying LI,

Frontiers of Chemical Science and Engineering 2010, Volume 4, Issue 2,   Pages 142-146 doi: 10.1007/s11705-009-0233-2

Abstract: TiO-AlOmixed oxides with different compositions ranging from 40wt-% to 95wt-% of TiO were prepared by sol-gel method and impregnated with different amounts of VO. Supports and catalysts were characterized by X-ray diffraction (XRD), physisorption, temperature preprogrammed reduction (H-TPR), and ammonia temperature programmed desorption (NH-TPD). TiO content in the support had obvious effect on the crystal structure, texture characteristic, acid property, and catalytic activity in dehydrogenation of ethylbenzene (EB) with carbon dioxide. The highest catalytic activity was acquired when the TiO content was 50 wt-%.

Keywords： desorption     different     TiO-AlOmixed     physisorption     ethylbenzene    

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Al2O3 and CeO2-promoted MgO sorbents for CO2 capture at moderate

Huimei Yu, Xiaoxing Wang, Zhu Shu, Mamoru Fujii, Chunshan Song

Frontiers of Chemical Science and Engineering 2018, Volume 12, Issue 1,   Pages 83-93 doi: 10.1007/s11705-017-1691-6

Abstract: A series of Al O and CeO modified MgO sorbents was prepared and studied for CO sorption at moderate temperatures. The CO sorption capacity of MgO was enhanced with the addition of either Al O or CeO . Over Al O -MgO sorbents, the best capacity of 24.6 mg-CO /g-sorbent was attained at 100 °C, which was 61% higher than that of MgO (15.3 mg-CO /g-sorbent). The highest capacity of 35.3 mg-CO /g-sorbent was obtained over the CeO -MgO sorbents at the optimal temperature of 200 °C. Combining with the characterization results, we conclude that the promotion effect on CO sorption with the addition of Al O and CeO can be attributed to the increased surface area with reduced MgO crystallite size. Moreover, the addition of CeO increased the basicity of MgO phase, resulting in more increase in the CO capacity than Al O promoter. Both the Al O -MgO and CeO -MgO sorbents exhibited better cyclic stability than MgO over the course of fifteen CO sorption-desorption cycles. Compared to Al O , CeO is more effective for promoting the CO capacity of MgO. To enhance the CO capacity of MgO sorbent, increasing the basicity is more effective than the increase in the surface area.

Keywords： CO2 capture     MgO sorbents     Al2O3     CeO2     flue gas    

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A Storage-Driven CO2 EOR for a Net-Zero Emission Target Article

Yueliang Liu, Zhenhua Rui

Engineering 2022, Volume 18, Issue 11,   Pages 79-87 doi: 10.1016/j.eng.2022.02.010

Abstract: >2 emissions by storing CO2 in oil reservoirs.CO2 EOR—whose main target is to realize net-zero or even negative CO2 emissionsStorage-driven CO2 EOR is superior to conventional CO2 EOR in improving sweepingthan conventional CO2 EOR.Moreover, the amount of sequestrated CO2 in storage-driven CO2 EOR exceeds the amount

Keywords： CO2     EOR     Net CO2     emissions     Dimethyl ether     Storage-driven CO2     EOR     CO2     sequestration    

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The stabilization effect of Al2O3 on unconventional Pb/SiO2 catalyst

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 10,   Pages 1423-1429 doi: 10.1007/s11705-023-2315-y

Abstract: To enhance the stability, the traditional carrier Al2O3 with a small amount, wasintroduced into Pb/SiO2 catalyst in this study.It has been proved that Al2O3 can inhibit the reduction of PbO, and weaken theAs a result, 3Al15Pb/SiO2 catalyst exhibits a much higher stability up to more than 150 h.addition, a simple schematic diagram of the change of surface species on the catalyst surface after Al2<

Keywords： Pb/SiO2     Al2O3     propane dehydrogenation     propene     stability    

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Biodegradation of 2-methylisoborneol by bacteria enriched from biological activated carbon

Rongfang YUAN, Beihai ZHOU, Chunhong SHI, Liying YU, Chunlei ZHANG, Junnong GU

Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 5,   Pages 701-710 doi: 10.1007/s11783-011-0367-6

Abstract: One of the most common taste and odour compounds (TOCs) in drinking water is 2-methylisoborneol (2-MIBFour bacterial strains for degrading 2-MIB were isolated from the surface of a biological activated carbonThe removal efficiencies of 2-MIB with initial concentrations of 515 ng·L were 98.4%, 96.3%, 95.0%,The kinetic model showed that biodegradation of 2-MIB at an initial dose of 4.2 mg·L was a pseudo-first-orderThese degraders decomposed 2-MIB to form 2-methylenebornane and 2-methyl-2-bornane as the products.

Keywords： 2-methylisoborneol (2-MIB)     biodegradation     2-methylenebornane     2-methyl-2-bornane     pseudo-first-order reaction    

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Encapsulation of 2-amino-2-methyl-1-propanol with tetraethyl orthosilicate for CO2 capture

Sidra Rama, Yan Zhang, Fideline Tchuenbou-Magaia, Yulong Ding, Yongliang Li

Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 4,   Pages 672-683 doi: 10.1007/s11705-019-1856-6

Abstract: The conventional emulsion technique was selected for the microcapsule formulation by using 2-amino-2-

Keywords： carbon capture     microencapsulated sorbents     emulsion technique     low temperature adsorption and absorption    

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Cu-doped Bi/Bi2WO6 catalysts for efficient N2 fixation by photocatalysis

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 10,   Pages 1412-1422 doi: 10.1007/s11705-023-2312-1

Abstract: In this paper, Cu-doped Bi2WO6 was synthesized via a solvothermal method and appliedit in photocatalytic N2 immobilization.metallic Bi in the photocatalyst, indicating that the synthesized photocatalyst is actually Bi/Cu-Bi22 and most likely substituted the position of Bi3+.Cu did not affect the metallic Bi content, but mainly influenced the energy band structure of Bi2<

Keywords： Bi2WO6     Cu doping     work function     photocatalytic N2 fixation     charge    

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Fenton oxidation of 2,4- and 2,6-dinitrotoluene and acetone inhibition

HE Yiliang, ZHAO Bin, HUGHES Joseph B., HAN Sung Soo

Frontiers of Environmental Science & Engineering 2008, Volume 2, Issue 3,   Pages 326-332 doi: 10.1007/s11783-008-0038-4

Abstract: The performances and kinetic parameters of Fenton oxidation of 2,4- and 2,6-dinitrotoluene (DNT) in water-acetone- and 2,6-DNT.- and 2,6-DNT completely, mainly due to the competition of hydroxyl radicals.Fenton oxidation of 2,4- and 2,6-DNT fit well with the first-order kinetics and the presence of acetone-DNT primary degradation was proposed: 2,4-DNT → 2,4-dinitro-benzaldehyde → 2,4-dinitrobenzoic acid →

Keywords： presence     2     4-DNT     competition     laboratory     scavenger    

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CO2 methanation and co-methanation of CO and CO2 over Mn-promoted Ni/Al2

Kechao Zhao,Zhenhua Li,Li Bian

Frontiers of Chemical Science and Engineering 2016, Volume 10, Issue 2,   Pages 273-280 doi: 10.1007/s11705-016-1563-5

Abstract: A series of Mn-promoted 15 wt-% Ni/Al O catalysts were prepared by an incipient wetness impregnation method. The effect of the Mn content on the activity of the Ni/Al O catalysts for CO methanation and the co-methanation of CO and CO in a fixed-bed reactor was investigated. The catalysts were characterized by N physisorption, hydrogen temperature-programmed reduction and desorption, carbon dioxide temperature-programmed desorption, X-ray diffraction and high-resolution transmission electron microscopy. The presence of Mn increased the number of CO adsorption sites and inhibited Ni particle agglomeration due to improved Ni dispersion and weakened interactions between the nickel species and the support. The Mn-promoted 15 wt-% Ni/Al O catalysts had improved CO methanation activity especially at low temperatures (250 to 400 °C). The Mn content was varied from 0.86% to 2.54% and the best CO conversion was achieved with the 1.71Mn-Ni/Al O catalyst. The co-methanation tests on the 1.71Mn-Ni/Al O catalyst indicated that adding Mn markedly enhanced the CO methanation activity especially at low temperatures but it had little influence on the CO methanation performance. CO methanation was more sensitive to the reaction temperature and the space velocity than the CO methanation in the co-methanation process.

Keywords： Mn promotion     nickel catalysts     CO2 methanation     co-methanation of CO and CO2    

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Synthesis of copolymers of 3-acryloyloxymethyl-3′-methyloxetane and 3-(2-(2-(2-Methoxyethylenoxy)ethylenoxy

YE Lin, ZHAO Yumei, FENG Zengguo, BAI Ying, WU Feng

Frontiers of Chemical Science and Engineering 2007, Volume 1, Issue 4,   Pages 343-348 doi: 10.1007/s11705-007-0062-0

Abstract: The cationic ring-opening copolymerization of AMO with another oxetane-derived monomer, 3-(2-(2-(2-methoxyethylenoxy

Keywords： 4-butanediol     2-methoxyethylenoxy     consistent     oxetane-derived     copolymer    

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Title Author Date Type Operation

Near-infrared fluorescent probe for fast track of cyclooxygenase-2 in Golgi apparatus in cancer cells

Bhaskar Gurram, Miao Li, Jiangli Fan, Jingyun Wang, Xiaojun Peng

Journal Article

Cyclooxygenase-2 gene-1195G/A genotype is associated with the risk of HBV-induced HCC: A case-control

Li-Feng LIU MD, PhD, Qiong CHEN MD, PhD, Ying CHANG MD, PhD, Ju-Sheng LIN MD, PhD, Jin-Liang ZHANG MM,

Journal Article

metastasis is related to the epithelial-mesenchymal transition and expressions of VEGF, MMP-9, and COX-2

Lihui WANG, Lianhong LI, Shen LV, Shujun FAN, Li ZHAN, Bo WANG, Zhong ZHANG

Journal Article

Efficacy and safety of perioperative parecoxib for acute postoperative pain treatment in children: a meta-analysis

Xueshan Bu,Lei Yang,Yunxia Zuo

Journal Article

Improvement in the synthesis of 2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(Z)-methoxyiminoacetic acid 2-benzothiazolyl

GAO Shihao, SUN Chenghui, ZHAO Xinqi, GAO Changquan

Journal Article

Effect of TiO 2 loading on the activity of V/TiO 2 -Al 2 O 3 in the catalytic oxidehydrogenation of ethylbenzene

Xiaohong LI, Wenying LI,

Journal Article

Al2O3 and CeO2-promoted MgO sorbents for CO2 capture at moderate

Huimei Yu, Xiaoxing Wang, Zhu Shu, Mamoru Fujii, Chunshan Song

Journal Article

A Storage-Driven CO2 EOR for a Net-Zero Emission Target

Yueliang Liu, Zhenhua Rui

Journal Article

The stabilization effect of Al2O3 on unconventional Pb/SiO2 catalyst

Journal Article

Biodegradation of 2-methylisoborneol by bacteria enriched from biological activated carbon

Rongfang YUAN, Beihai ZHOU, Chunhong SHI, Liying YU, Chunlei ZHANG, Junnong GU

Journal Article

Encapsulation of 2-amino-2-methyl-1-propanol with tetraethyl orthosilicate for CO2 capture

Sidra Rama, Yan Zhang, Fideline Tchuenbou-Magaia, Yulong Ding, Yongliang Li

Journal Article

Cu-doped Bi/Bi2WO6 catalysts for efficient N2 fixation by photocatalysis

Journal Article

Fenton oxidation of 2,4- and 2,6-dinitrotoluene and acetone inhibition

HE Yiliang, ZHAO Bin, HUGHES Joseph B., HAN Sung Soo

Journal Article

CO2 methanation and co-methanation of CO and CO2 over Mn-promoted Ni/Al2

Kechao Zhao,Zhenhua Li,Li Bian

Journal Article

Synthesis of copolymers of 3-acryloyloxymethyl-3′-methyloxetane and 3-(2-(2-(2-Methoxyethylenoxy)ethylenoxy

YE Lin, ZHAO Yumei, FENG Zengguo, BAI Ying, WU Feng

Journal Article