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《医学前沿(英文)》 2011年 第5卷 第1期 页码 101-105 doi: 10.1007/s11684-011-0111-4
It has been demonstrated that β-elemene could protect against carbon tetrachloride (CCl4)-induced liver fibrosis in our laboratory work, and the aim of this paper is to reveal the protective mechanisms of β-elemene. The hepatic fibrosis experimental model was induced by the hypodermical injection of CCl4 in Wistar male rats. β-elemene was intraperitoneally administered into rats for 8 weeks (0.1 mL/100 g bodyweight per day), and plasma endotoxin content was assayed by biochemistry. The serum TNF-α level was detected using radioactive immunity. CD14 expression in rat livers was measured by immunohistochemistry and Western blot. The results showed that β-elemene can downregulate the levels of plasma endotoxins, serum TNF-α, and hepatic CD14 expression in rats with liver fibrosis. β-elemene plays an important role in downregulating the lipopolysaccharide signal transduction pathway, a significant pathway in hepatic fibrosis development.
Rui ZHU MD , Lin SHEN MD , Jianguo LIU MD , Weili ZHANG MM , Ling YANG MD ,
《医学前沿(英文)》 2009年 第3卷 第3期 页码 363-367 doi: 10.1007/s11684-009-0064-z
关键词: liver disease alcohol Zhihuang decoction CD14 signal transduction
《医学前沿(英文)》 2022年 第16卷 第1期 页码 139-149 doi: 10.1007/s11684-021-0835-8
关键词: B-cell acute lymphoblastic leukemia bispecific antibody trispecific antibody CD19 CD20
Clinical significance of CD34+CD117dim/CD34+CD117bri myeloblast-associated
Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang
《医学前沿(英文)》 2021年 第15卷 第4期 页码 608-620 doi: 10.1007/s11684-021-0836-7
关键词: t(8 21)(q22 q22) AML CD34+CD117dim/ CD34+CD117bri cell population gene expression prognosis
Special Issue for the 14th Global Chinese Chemical Engineering Symposium
《化学科学与工程前沿(英文)》 2023年 第17卷 第10期 页码 1321-1322 doi: 10.1007/s11705-023-2351-7
Meng XUE, Yihui ZHOU, Zhongyi YANG, Biyun LIN, Jiangang YUAN, Shanshan WU
《环境科学与工程前沿(英文)》 2014年 第8卷 第2期 页码 226-238 doi: 10.1007/s11783-013-0582-4
关键词:
cadmium (Cd)
low-Cd cultivar
pakchoi (
Heterologous expression of signal protein 14-3-3 in and the subsequent immune response in mice
ZHENG Meijuan, SHEN Jilong, LUO Qingli, XU Yuanhong
《医学前沿(英文)》 2008年 第2卷 第1期 页码 95-99 doi: 10.1007/s11684-008-0017-y
关键词: development challenging rSj14-3-3 resistance cultural supernatant
《环境科学与工程前沿(英文)》 2023年 第17卷 第7期 doi: 10.1007/s11783-023-1687-z
● Organic solvent extracted fewer Cd/Pb in rapeseed oil than physical pressing.
关键词: Rapeseed oil Oil extraction technologies Human health risk assessment Cd/Pb-contaminated farmland Substitute planting
Celecoxib in combination with retinoid CD437 inhibits melanoma A375 cell
Jianwen REN, Zhenhui PENG, Birong GUO, Min PAN
《医学前沿(英文)》 2009年 第3卷 第1期 页码 108-112 doi: 10.1007/s11684-009-0015-8
关键词: celecoxib CD437 melanoma A375 cell apoptosis cycle arrest
SUN Yuebing, ZHOU Qixing, WEI Shuhe, REN Liping
《环境科学与工程前沿(英文)》 2007年 第1卷 第1期 页码 107-113 doi: 10.1007/s11783-007-0020-6
《医学前沿(英文)》 doi: 10.1007/s11684-023-1010-1
关键词: exosomes induce activation impair function CD19 exosomal CD19 antigen
《结构与土木工程前沿(英文)》 2021年 第15卷 第6期 页码 1504-1506 doi: 10.1007/s11709-021-0782-0
Prevalence of asthma symptoms in Golestan schoolchildren aged 6–7 and 13–14 years in Northeast Iran
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《医学前沿(英文)》 2016年 第10卷 第3期 页码 345-350 doi: 10.1007/s11684-016-0462-y
Asthma is the most common chronic disease among children, and its incidences are often imminent among elementary schoolchildren. This study aimed to examine the prevalence of asthma symptoms in Golestan schoolchildren aged 6–7 and 13–14 years in Northeast Iran. The prevalence rate was compared according to age group (aged 6–7 years vs. aged 13–14 years) and gender (male vs. female). In this cross-sectional study, 1706 Iranian schoolchildren aged 6–7 and 13–14 years in Golestan Province were enrolled. Participants completed questionnaires between February and July 2014. Asthma symptoms were assessed using the questionnaire of the International Study of Asthma and Allergies in Childhood protocol in Persian. The logistic regression model was used to estimate the odds ratios (ORs) and 95% confidence intervals (CIs) of the asthma symptoms for each of the gender and age groups. The prevalence rates of “current asthma” symptoms and “asthma ever” in all the children were estimated as 9.5% and 7.5%, respectively. The prevalence of asthma (“asthma ever” and “wheezing in the past 12 months”) in junior high schoolchildren (aged 13–14 years) is higher than that in elementary schoolchildren (aged 6–7 years) (P <0.05). The prevalence of the severity of wheezing in girls is lower than that in boys (OR= 1.7, 95%CI= 1.06–2.96, P = 0.02). Asthma is still a major public health problem. This study shows that the prevalence of the asthma symptoms in boys is lower than that in girls in both age groups, and the severity of asthma in girls is higher than that in boys aged 13–14 years.
关键词: asthma asthma symptoms epidemiology childhood chronic disease
Changes of phenotype and function of human CD4 CD25 T cells induced by transfection of Foxp3
WU Kui, BI Yutian, WANG Yaoli, WANG Changzheng
《医学前沿(英文)》 2008年 第2卷 第4期 页码 366-369 doi: 10.1007/s11684-008-0070-6
CD47 blockade improves the therapeutic effect of osimertinib in non-small cell lung cancer
《医学前沿(英文)》 2023年 第17卷 第1期 页码 105-118 doi: 10.1007/s11684-022-0934-1
关键词: osimertinib anti-CD47 antibody combination strategy ADCP EGFR
标题 作者 时间 类型 操作
Downregulation effects of beta-elemene on the levels of plasma endotoxin, serum TNF-alpha, and hepatic CD14
null
期刊论文
Effect of decoction on CD14 expression in lipopolysaccharide signal transduction pathway of alcohol-induced
Rui ZHU MD , Lin SHEN MD , Jianguo LIU MD , Weili ZHANG MM , Ling YANG MD ,
期刊论文
Preclinical characterization and comparison between CD3/CD19 bispecific and novel CD3/CD19/CD20 trispecific
期刊论文
Clinical significance of CD34+CD117dim/CD34+CD117bri myeloblast-associated
Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang
期刊论文
Comparisons in subcellular and biochemical behaviors of cadmium between low-Cd and high-Cd accumulation
Meng XUE, Yihui ZHOU, Zhongyi YANG, Biyun LIN, Jiangang YUAN, Shanshan WU
期刊论文
Heterologous expression of signal protein 14-3-3 in and the subsequent immune response in mice
ZHENG Meijuan, SHEN Jilong, LUO Qingli, XU Yuanhong
期刊论文
Cultivars and oil extraction techniques affect Cd/Pb contents and health risks in oil of rapeseed grownon Cd/Pb-contaminated farmland
期刊论文
Celecoxib in combination with retinoid CD437 inhibits melanoma A375 cell
Jianwen REN, Zhenhui PENG, Birong GUO, Min PAN
期刊论文
Growth responses of the newly-discovered Cd-hyperaccumulator Rorippa globosa and its accumulation characteristicsof Cd and As under joint stress of Cd and As
SUN Yuebing, ZHOU Qixing, WEI Shuhe, REN Liping
期刊论文
Tumor-derived exosomes induce initial activation by exosomal CD19 antigen but impair the function ofCD19-specific CAR T-cells via TGF-β signaling
期刊论文
Prediction on CO uptake of recycled aggregate concrete”, Frontiers of Structural and Civil Engineering, 14
期刊论文
Prevalence of asthma symptoms in Golestan schoolchildren aged 6–7 and 13–14 years in Northeast Iran
null
期刊论文
Changes of phenotype and function of human CD4 CD25 T cells induced by transfection of Foxp3
WU Kui, BI Yutian, WANG Yaoli, WANG Changzheng
期刊论文