资源类型

期刊论文 1338

会议视频 27

会议信息 5

年份

2024 3

2023 179

2022 186

2021 214

2020 110

2019 75

2018 48

2017 62

2016 47

2015 56

2014 58

2013 56

2012 35

2011 32

2010 50

2009 39

2008 24

2007 42

2006 3

2005 2

展开 ︾

关键词

SARS-CoV-2 7

微波散射计 5

碳中和 5

COVID-19 4

Cu(In 4

HY-2 4

2019 3

2型糖尿病 3

GPS 3

Ga)Se2 3

HY-2 卫星 3

HY-2A卫星 3

代谢与免疫 3

光催化 3

工程管理 3

微波辐射计 3

营养健康 3

CCS 2

CO2利用 2

展开 ︾

检索范围：

排序： 展示方式：

Autoimmunity in acute ischemic stroke and the role of blood—brain barrier: the dark side or the light one?

Nikolay V. Tsygan, Alexandr P. Trashkov, Igor V. Litvinenko, Viktoriya A. Yakovleva, Alexandr V.Vasiliev, Leonid P. Churilov

《医学前沿（英文）》 2019年 第13卷 第4期   页码 420-426 doi: 10.1007/s11684-019-0688-6

摘要： This article presents a synopsis of the current data on the mechanisms of blood—brain barrier (BBB) alteration and autoimmune response in acute ischemic stroke. Most researchers confirm the relationship between the severity of immunobiochemical changes and clinical outcome of acute ischemic stroke. Ischemic stroke is accompanied by aseptic inflammation, which alters the brain tissue and exposes the co-stimulatory molecules of the immune system and the neuronal antigens. To date, BBB is not considered the border between the immune system and central nervous system, and the local immune subsystems are found within and behind the BBB. BBB disruption contributes to the leakage of brain autoantigens and induction of secondary autoimmune response to neuronal antigens and long-term inflammation. Glymphatic system function is altered and jeopardized both in hemorrhagic and ischemic stroke types. The receptors of innate immunity (toll-like receptor-2 and toll-like receptor-4) are also involved in acute ischemia—reperfusion injury. Immune response is related to the key processes of blood clotting and fibrinolysis. At the same time, the stroke-induced immune activation may promote reparation phenomena in the brain. Subsequent research on the reduction of the acute ischemic brain injury through the target regulation of the immune response is promising.

关键词： stroke     blood–brain barrier     autoimmunity     innate immunity     inflammation     cell death    

HTML PDF 收藏

Possible role of power-to-vehicle and vehicle-to-grid as storages and flexible loads in the German 110 kV distribution grid

Erik BLASIUS

《能源前沿（英文）》 2017年 第11卷 第2期   页码 146-154 doi: 10.1007/s11708-017-0475-5

摘要： The sectoral coupling of road traffic (in form of E-Mobility) and electrical energy supply (known as power-to-vehicle (P2V), vehicle-to-grid (V2G) is discussed as one of the possible development concepts for the flexible system integration of renewable energy sources (RES) and the support of the objectives of the German energy transition (aka. Energiewende). It is obvious that E-mobility, which shall produce as few emissions as possible, should be based on the exclusive use of renewable energies. At the same time, the E-mobility can help to reduce the negative effects of the grid integration of RES to the distribution grids. However, this assumes that the electric vehicles are smart integrated to the grids where they charge, meaning that they must be able to communicate and be controllable. Because per se unplanned and uncontrollable charging processes are harmful for the grid operation, especially if they occur frequently and unexpected in similar time periods, the effects can hardly be controlled and can lead to serious technical problems in practical grid operation. This paper provides an insight into the current development of E-mobility in Germany. The insight will be matched with the German development of the RES. By the combination of both sectors, the possible role of the E-mobility for the distribution grid will be depicted, which can have positive and negative aspects.

关键词： P2V     V2G     grid integration     electric vehicles     distribution grid    

HTML PDF 收藏

Non-thermal plasma for exhaust gases treatment

,Marquidia PACHECO P.,Fernando GÓMEZ B.,Joel PACHECO P.,Arturo COLÍN C.,Víctor SÁNCHEZ-MENDIETA,Ricardo VALDIVIA B.,Alfredo SANTANA D.,José HUERTAS C.,Hilda FRÍAS P.

《机械工程前沿（英文）》 2015年 第10卷 第3期   页码 301-305 doi: 10.1007/s11465-015-0344-z

摘要：

This article describes a study on a non-thermal plasma device to treat exhaust gases in an internal combustion engine. Several tests using a plasma device to treat exhaust gases are conducted on a Honda GX200-196 cm3 engine at different rotational speeds. A plasma reactor could be efficient in degrading nitrogen oxides and particulate matter. Monoxide and carbon dioxide treatment is minimal. However, achieving 1%–3% degradation may be interesting to reduce the emission of greenhouse gases.

关键词： plasma treatment     NOx     CO     CO2     particulate matter     vehicle    

HTML PDF 收藏

A low power, eco-friendly multipurpose thermoelectric refrigerator

N. Jagan Mohan REDDY

《能源前沿（英文）》 2016年 第10卷 第1期   页码 79-87 doi: 10.1007/s11708-015-0380-8

摘要： There has been an immense endeavor to mitigate global warming in spite of which it has only been worse. This paper presents the design and implementation of a low power and eco-friendly refrigeration system using the thermoelectric effect. The conventional refrigerators make use of complex mechanisms which involves synchronous operation of various units, namely the compressor, condensers, expansion valves, evaporator, refrigerant and so on. But a thermoelectric refrigerator exploits the principle of the Peltier effect, thus avoiding the utilization of these complex components. This even helps curb the release of harmful chlorofluorocarbons (CFCs) into the atmosphere which contributes to the increase in global temperature. Moreover, the temperature can be controlled and set to required values with the help of a microcontroller. Hence, this can be used both for domestic and commercial purposes. The unit does not eject any harmful gases. Therefore, the heat expelled from the unit can be tapped for heating utilities, making the use of this device versatile in its application. Thus this proposal aims not only at reducing the air pollutants by not contributing to it but also at reducing the power consumption.

关键词： low power     eco-friendly     multipurpose     TEC-12706     Peltier effect     microcontroller (P89V51RD2BN)     temperature control    

HTML PDF 收藏

P2P energy trading via public power networks: Practical challenges, emerging solutions, and the way forward

《能源前沿（英文）》 2023年 第17卷 第2期   页码 189-197 doi: 10.1007/s11708-023-0873-9

摘要： Peer-to-peer (P2P) energy trading is an emerging energy supply paradigm where customers with distributed energy resources (DERs) are allowed to directly trade and share electricity with each other. P2P energy trading can facilitate local power and energy balance, thus being a potential way to manage the rapidly increasing number of DERs in net zero transition. It is of great importance to explore P2P energy trading via public power networks, to which most DERs are connected. Despite the extensive research on P2P energy trading, there has been little large-scale commercial deployment in practice across the world. In this paper, the practical challenges of conducting P2P energy trading via public power networks are identified and presented, based on the analysis of a practical Local Virtual Private Networks (LVPNs) case in North Wales, UK. The ongoing efforts and emerging solutions to tackling the challenges are then summarized and critically reviewed. Finally, the way forward for facilitating P2P energy trading via public power networks is proposed.

关键词： distribution network     local virtual private network     network charges     peer-to-peer (P2P) energy trading     practical implementation.    

HTML PDF 收藏

Adsorption of 1,3-propanediol from synthetic mixture using polymeric resin as adsorbents

SHOTIPRUK, V. TANTAYAKOM, P. PRASITCHOKE, C. MUANGNAPOH

《化学科学与工程前沿（英文）》 2009年 第3卷 第1期   页码 52-57 doi: 10.1007/s11705-009-0087-7

摘要： The aim of this work was to separate 1,3-PDO from a synthetic mixture using polymeric resins, Amberlite XAD-7 and XAD-16 resins. The equilibrium adsorption of 1,3-PDO onto two polymeric resins were investigated in binary and tertiary systems. Experimental results of binary component adsorption equilibrium indicated that the adsorption capacity ( ) of 1,3-PDO at 160 g/L onto XAD-7 and XAD-16 was 835.96 and 584.61 mg 1,3-PDO/g dry resin, respectively. The adsorption isotherms were closely predicted by the Langmuir-Freundlich model among the two isotherm model tested. The value of n of 1,3-PDO adsorbed on XAD-7 are much higher than those on XAD-16. This result suggested that XAD-7 resin has a higher affinity for the 1,3-PDO adsorption than XAD-16 resin. Moreover, the value of adsorption capacity of 1,3-PDO in the binary and tertiary component were compared at the same conditions. In the tertiary system, although the selectivity of 1,3-PDO from XAD-7 was approximately six times higher than XAD-16, the adsorption capacity of 1,3-PDO at 160 g/L onto XAD-16 was higher than XAD-7. Interestingly, the reusability of XAD-7 and XAD-16 resins in the three cycle times shows a slight loss of adsorption capacity. Furthermore, the investigation about desorption by an ethanol/water mixture at 50% ( / ) indicated that the desorption yield of 1,3-PDO from XAD-7 was lower than XAD-16 resin for both the binary and tertiary component. This was due to the more favorable adsorption characteristics of XAD-7 resin than XAD-16 resin.

关键词： adsorption     1     3-propanediol     glycerol     polymeric resin     adsorption isotherm    

HTML PDF 收藏

面向服务的P2P网络体系结构层次参考模型研究

刘业,刘林峰,庄艳艳

《中国工程科学》 2007年 第9卷 第9期   页码 72-77

摘要： <p style="text-align: justify;">提出了一种基于交互、 面向服务的P2P网络体系结构框 架模型ISPNA，同时结合P2P网络 松耦合、自组织、可缩放等特点， 对P2P网络技术中增强其可用性需从P2P网络体系结构的研究角度出发， 将增强P2P网络可用性所需要考虑的 多方面因素放置在P2P网络的不同 层次予以解决，有利于从宏观上 把握需要解决的问题。p>

关键词： P2P网络     体系结构     层次参考模型     资源     服务    

HTML PDF 收藏

Observation of a higher JAK2 V617F homozygous mutated clone in polycythemia vera compared to essential

LIU Hongxing, TONG Chunrong, CAI Peng, GU Jiangying, LIN Yuehui, TENG Wen, WANG He, ZHANG Ying, ZHU Ping

《医学前沿（英文）》 2008年 第2卷 第3期   页码 309-313 doi: 10.1007/s11684-008-0059-1

摘要： Single-tube bi-directional allele specific amplification (SB-ASA) and real-time quantitative polymerase chain reaction (RQ-PCR) assays were developed and performed for JAK2V617F detection on 40 polycythemia vera (PV) samples, 31 essential thrombocythemia (ET) samples, 40 acute leukemia samples, and 40 healthy control samples. Differences between detect limitations of the two assays and their influence on the mutation detection rate were analyzed. The results showed that in some samples, the JAK2V617F burden was as low as nearly 1%, and thus more JAK2V617F-positive samples were detected by RQ-PCR than by SB-ASA assay due to the former higher detect limitation. Mutation allele ratios in PV and ET samples and their relevance to biological characteristics were also analyzed. The results showed that the mutation allele ratio was 0.436 ± 0.261 in PV, higher than the 0.216 ± 0.207 in ET; percentage of certainly homozygous mutation carriers in PV was 40.54%, higher than the 10% in ET. However, statistical analysis showed no relevance between mutation allele burden and sex or age. Our result shows that the pathogenesis of PV and ET may be related to the mutation allele burden of JAK2V617F.

关键词： specific amplification     essential thrombocythemia     Single-tube bi-directional     JAK2V617F-positive     JAK2V617F detection    

HTML PDF 收藏

Effect of TiO 2 loading on the activity of V/TiO 2 -Al 2 O 3 in the catalytic oxidehydrogenation of ethylbenzene

Xiaohong LI, Wenying LI,

《化学科学与工程前沿（英文）》 2010年 第4卷 第2期   页码 142-146 doi: 10.1007/s11705-009-0233-2

摘要： TiO-AlOmixed oxides with different compositions ranging from 40wt-% to 95wt-% of TiO were prepared by sol-gel method and impregnated with different amounts of VO. Supports and catalysts were characterized by X-ray diffraction (XRD), physisorption, temperature preprogrammed reduction (H-TPR), and ammonia temperature programmed desorption (NH-TPD). TiO content in the support had obvious effect on the crystal structure, texture characteristic, acid property, and catalytic activity in dehydrogenation of ethylbenzene (EB) with carbon dioxide. The highest catalytic activity was acquired when the TiO content was 50 wt-%.

关键词： desorption     different     TiO-AlOmixed     physisorption     ethylbenzene    

HTML PDF 收藏

化学工程中机器学习的优势、限制、机会和挑战 Perspective

Dobbelaere, Pieter P. Plehiers, Ruben Van de Vijver, Christian V. Stevens, Kevin M. Van Geem

《工程（英文）》 2021年 第7卷 第9期   页码 1201-1211 doi: 10.1016/j.eng.2021.03.019

摘要： <p style="text-align: justify;">化学工程师依靠模型进行工程设计、研究和日常决策制定，因为这些工作通常会伴有较大的财务和安全方面的风险。p>

关键词： 人工智能     机器学习     反应工程     过程工程    

HTML PDF 收藏

Fine-grained P2P traffic classification by simply counting flows

Jie HE,Yue-xiang YANG,Yong QIAO,Wen-ping DENG

《信息与电子工程前沿（英文）》 2015年 第16卷 第5期   页码 391-403 doi: 10.1631/FITEE.1400267

摘要： The continuous emerging of peer-to-peer (P2P) applications enriches resource sharing by networks, but it also brings about many challenges to network management. Therefore, P2P applications monitoring, in particular, P2P traffic classification, is becoming increasingly important. In this paper, we propose a novel approach for accurate P2P traffic classification at a fine-grained level. Our approach relies only on counting some special flows that are appearing frequently and steadily in the traffic generated by specific P2P applications. In contrast to existing methods, the main contribution of our approach can be summarized as the following two aspects. Firstly, it can achieve a high classification accuracy by exploiting only several generic properties of flows rather than complicated features and sophisticated techniques. Secondly, it can work well even if the classification target is running with other high bandwidth-consuming applications, outperforming most existing host-based approaches, which are incapable of dealing with this situation. We evaluated the performance of our approach on a real-world trace. Experimental results show that P2P applications can be classified with a true positive rate higher than 97.22% and a false positive rate lower than 2.78%.

关键词： Traffic classification     Peer-to-peer (P2P)     Fine-grained     Host-based    

HTML PDF 收藏

Diporphyrin tweezer for multichannel spectroscopic analysis of enantiomeric excess

Chahal, Václav Březina, Whitney A.Webre, Katsuhiko Ariga, Francis D’Souza, Jan Labuta, Jonathan P. Hill

《化学科学与工程前沿（英文）》 2020年 第14卷 第1期   页码 28-40 doi: 10.1007/s11705-019-1869-1

摘要： Chiral 1,1’-binaphthyl-linked diporphyrin ‘tweezers’ ( )- /( )- and the corresponding zinc(II) complexes ( )- /( )- were prepared as chiral host molecules, and their utility for chiral analyses (especially enantiomeric excess ( ) determinations) were evaluated. Tris(1- -dodecyl)porphyrins were used for the first time as the interacting units. Host capabilities of the diporphyrin tweezers were investigated by titrations with ( , )- and ( , )-cyclohexane-1,2-diamine (CHDA). The host molecules could be used as multichannel probes of by using UV-vis, circular dichroism (CD), fluorescence emission and H nuclear magnetic resonance ( H-NMR) methods. Chiral configurations could also be differentiated using CD or H-NMR spectroscopy. All three optical techniques give good resolution of with reasonable sensitivity considering the low concentrations used (ca. 10 mol·L ). The determination of CHDA enantiomers using NMR spectroscopy is also possible because of the reasonably well separated resonances in the case of ( , )- and ( , )-CHDA. Non-metallated ( )- /( )- hosts could not be used to detect chiral information in a strongly acidic chiral guest. This work demonstrates the utility of 1,1’-binapthyl-linked chiral hosts for chiral analysis of ditopically interacting enantiomers.

关键词： porphyrin dimer     chirality     enantiomeric excess     CD     fluorescence    

HTML PDF 收藏

Effective regeneration of thermally deactivated commercial V-W-Ti catalysts

Xuesong SHANG, Jianrong LI, Xiaowei YU, Jinsheng CHEN, Chi HE

《化学科学与工程前沿（英文）》 2012年 第6卷 第1期   页码 38-46 doi: 10.1007/s11705-011-1167-z

摘要： An effective method for the regeneration of thermally deactivated commercial monolith SCR catalysts was investigated. Two types of regenerated solutions, namely NH Cl (1 mol/L) and dilute H SO (0.5 mol/L), were employed to treat the used catalyst. The effects of temperature and the regeneration process on the structural and textural properties of the catalysts were determined by X-ray diffraction, scanning electron microscopy, N adsorption/desorption, elemental analysis and Fourier transform infrared spectroscopy. The results suggest that the anatase phase of the used catalyst is maintained after exposure to high temperatures. Some of the catalytic activity was restored after regeneration. The catalyst regenerated by aqueous NH Cl had a higher activity than that of the catalyst treated by dilute H SO . The main reason is that the NH generated from the decomposition of NH Cl at high temperatures can be adsorbed onto the catalyst which promotes the reaction. The aggregated V O were partially re-dispersed during the regeneration process, and the intrinsic oxidation of ammonia with high concentrations of O is a factor that suppresses the catalytic activity.

关键词： V2O5-WO3/TiO2 catalysts     thermal deactivation     regeneration     NH4Cl     dilute H2SO4 solution    

HTML PDF 收藏

matter 2.5 triggers airway inflammation and bronchial hyperresponsiveness in mice by activating the SIRT2--p65 pathway

《医学前沿（英文）》 2021年 第15卷 第5期   页码 750-766 doi: 10.1007/s11684-021-0839-4

摘要： Exposure to particulate matter 2.5 (PM2.5) potentially triggers airway inflammation by activating nuclear factor-κB (NF-κB). Sirtuin 2 (SIRT2) is a key modulator in inflammation. However, the function and specific mechanisms of SIRT2 in PM2.5-induced airway inflammation are largely understudied. Therefore, this work investigated the mechanisms of SIRT2 in regulating the phosphorylation and acetylation of p65 influenced by PM2.5-induced airway inflammation and bronchial hyperresponsiveness. Results revealed that PM2.5 exposure lowered the expression and activity of SIRT2 in bronchial tissues. Subsequently, SIRT2 impairment promoted the phosphorylation and acetylation of p65 and activated the NF-κB signaling pathway. The activation of p65 triggered airway inflammation, increment of mucus secretion by goblet cells, and acceleration of tracheal stenosis. Meanwhile, p65 phosphorylation and acetylation, airway inflammation, and bronchial hyperresponsiveness were deteriorated in SIRT2 knockout mice exposed to PM2.5. Triptolide (a specific p65 inhibitor) reversed p65 activation and ameliorated PM2.5-induced airway inflammation and bronchial hyperresponsiveness. Our findings provide novel insights into the molecular mechanisms underlying the toxicity of PM2.5 exposure. Triptolide inhibition of p65 phosphorylation and acetylation could be an effective therapeutic approach in averting PM2.5-induced airway inflammation and bronchial hyperresponsiveness.

关键词： particulate matter 2.5     sirtuin 2     p65     airway inflammation     bronchial hyperresponsiveness     triptolide    

HTML PDF 收藏

Mechanisms of connective tissue formation and blocks of mitogen activated protein kinase

Irina A SHURYGINA, Michael G SHURYGIN, Nataliya I AYUSHINOVA, Galina B GRANINA, Nikolay V ZELENIN

《化学科学与工程前沿（英文）》 2012年 第6卷 第2期   页码 232-237 doi: 10.1007/s11705-012-1286-1

摘要： Ninety male Wistar rats were selected under the “Guide for the Care and Use of Laboratory Animals” for skin-muscle wound models. Three groups of animals were examined respectively for inoculation of inhibitor of p38 MAPK (mitogen activated protein kinase) SB 203580 and JNK inhibitor SP 600125, and a control. Light microscopy, immunohistochemistry, and tensometry revealed that the inhibition of p38 or JNK cascades have modified the formation of the connective tissue scar. The degree of connective tissue growth in the area of surgical wound had been significantly reduced by the end of observation (30 d) as the SB 203580 was applied (% volume of collagen 43.60 (41.05 – 60.15) 73.54 (66.87 – 78.01) in control, = 0.002). Conversely, when we have applied the JNK blocker, the density of collagen in scar tissue increased (78.14 (72.77 – 81.14), = 0.022 control). SB203580 inhibits the expression of p38, c-Jun and c-Fos. When we have used the JNK blocker, the expression of c-Fos and c-Jun decreased, but the expression of p38 increased. This determines the high functional activity of fibroblasts after using SP 600125. Obtained results show the importance of studying regulators of cell differentiation as potential drugs, which significantly affect the outcome of the pathological processes.

关键词： connective tissue     mitogen activated protein kinase (MAPK)     p38     JNK    

HTML PDF 收藏

标题 作者 时间 类型 操作

Autoimmunity in acute ischemic stroke and the role of blood—brain barrier: the dark side or the light one?

Nikolay V. Tsygan, Alexandr P. Trashkov, Igor V. Litvinenko, Viktoriya A. Yakovleva, Alexandr V.Vasiliev, Leonid P. Churilov

期刊论文

Possible role of power-to-vehicle and vehicle-to-grid as storages and flexible loads in the German 110 kV distribution grid

Erik BLASIUS

期刊论文

Non-thermal plasma for exhaust gases treatment

,Marquidia PACHECO P.,Fernando GÓMEZ B.,Joel PACHECO P.,Arturo COLÍN C.,Víctor SÁNCHEZ-MENDIETA,Ricardo VALDIVIA B.,Alfredo SANTANA D.,José HUERTAS C.,Hilda FRÍAS P.

期刊论文

A low power, eco-friendly multipurpose thermoelectric refrigerator

N. Jagan Mohan REDDY

期刊论文

P2P energy trading via public power networks: Practical challenges, emerging solutions, and the way forward

期刊论文

Adsorption of 1,3-propanediol from synthetic mixture using polymeric resin as adsorbents

SHOTIPRUK, V. TANTAYAKOM, P. PRASITCHOKE, C. MUANGNAPOH

期刊论文

面向服务的P2P网络体系结构层次参考模型研究

刘业,刘林峰,庄艳艳

期刊论文

Observation of a higher JAK2 V617F homozygous mutated clone in polycythemia vera compared to essential

LIU Hongxing, TONG Chunrong, CAI Peng, GU Jiangying, LIN Yuehui, TENG Wen, WANG He, ZHANG Ying, ZHU Ping

期刊论文

Effect of TiO 2 loading on the activity of V/TiO 2 -Al 2 O 3 in the catalytic oxidehydrogenation of ethylbenzene

Xiaohong LI, Wenying LI,

期刊论文

化学工程中机器学习的优势、限制、机会和挑战

Dobbelaere, Pieter P. Plehiers, Ruben Van de Vijver, Christian V. Stevens, Kevin M. Van Geem

期刊论文

Fine-grained P2P traffic classification by simply counting flows

Jie HE,Yue-xiang YANG,Yong QIAO,Wen-ping DENG

期刊论文

Diporphyrin tweezer for multichannel spectroscopic analysis of enantiomeric excess

Chahal, Václav Březina, Whitney A.Webre, Katsuhiko Ariga, Francis D’Souza, Jan Labuta, Jonathan P. Hill

期刊论文

Effective regeneration of thermally deactivated commercial V-W-Ti catalysts

Xuesong SHANG, Jianrong LI, Xiaowei YU, Jinsheng CHEN, Chi HE

期刊论文

matter 2.5 triggers airway inflammation and bronchial hyperresponsiveness in mice by activating the SIRT2--p65 pathway

期刊论文

Mechanisms of connective tissue formation and blocks of mitogen activated protein kinase

Irina A SHURYGINA, Michael G SHURYGIN, Nataliya I AYUSHINOVA, Galina B GRANINA, Nikolay V ZELENIN

期刊论文