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Research on the method of cavitations resistance in a piezoelectric pump with 3-dimensional mesh structure

ZHANG Jian-hui, Bai Heng-jun, XIA Qi-xiao, NING Hong-gang, ONUKI Akiyoshi

《机械工程前沿(英文)》 2006年 第1卷 第4期   页码 429-433 doi: 10.1007/s11465-006-0052-9

摘要: The volume valve piezoelectric pump has received increasing attention from many areas because of its different characteristics such as the absence of chemical pollution and electromagnetic pollution. However, when the pump is working, it produces cavitations and the air bubbles that originate from these will flow out of the pump. Cavitations occurring in the pump will bring out noise and shorten the life of the pump. Furthermore, air bubbles flowing out of the pump will hinder its application in areas such as medical treatment and health care where blood transfusion and infusion are concerned. As a solution to this disadvantage, the CR3DMS (cavitations resistance with 3-dimensional mesh structure) method is developed, which is tested and verified to be effective on not only reducing the occurrence of cavitations and eliminating cavitations flowing out, but also restraining the emission of noise. In conclusion, the pump with CR3DMS, on the relationship between flow and driving frequency and the relationship between flow and the number of Resistant-Layers in both theory and test, are analyzed.

关键词: different     3-dimensional     occurrence     effective     Resistant-Layers    

Crushed rocks stabilized with organosilane and lignosulfonate in pavement unbound layers: Repeated load

Diego Maria BARBIERI, Inge HOFF, Chun-Hsing HO

《结构与土木工程前沿(英文)》 2021年 第15卷 第2期   页码 412-424 doi: 10.1007/s11709-021-0700-5

摘要: The creation of the new “Ferry-Free Coastal Highway Route E39” in southwest Norway entails the production of a remarkable quantity of crushed rocks. These resources could be beneficially employed as aggregates in the unbound courses of the highway itself or other road pavements present nearby. Two innovative stabilizing agents, organosilane and lignosulfonate, can significantly enhance the key properties, namely, resilient modulus and resistance against permanent deformation, of the aggregates that are excessively weak in their natural state. The beneficial effect offered by the additives was thoroughly evaluated by performing repeated load triaxial tests. The study adopted the most common numerical models to describe these two key mechanical properties. The increase in the resilient modulus and reduction in the accumulated vertical permanent deformation show the beneficial impact of the additives. Furthermore, a finite element model was created to simulate the repeated load triaxial test by implementing nonlinear elastic and plastic constitutive relationships.

关键词: organosilane     lignosulfonate     crushed rocks     pavement unbound layers     repeated load triaxial test     finite element analysis    

Analyses of the seismic responses of soil layers with deep deposits

LOU Menglin, LI Yuchun, LI Nansheng

《结构与土木工程前沿(英文)》 2007年 第1卷 第2期   页码 188-193 doi: 10.1007/s11709-007-0021-3

摘要: Several typical problems in the seismic response analysis of soil layers with deep deposits have been studied according to the seismic response analysis of the soil layer in the Shanghai region. The problems include the effect of the inclination of the bedrock under the soil layer on the seismic responses of the soil layer, the rationality of the artificial horizontal bedrock boundary in the soil layer, and the effect of the wave velocity of the bedrock and dynamic characteristics of the soil media on the seismic responses of the soil layer. Some results are obtained by numerical analysis. In the seismic response analysis, the effect of angle of inclination of the rock surface under the soil layer can be neglected if the angle is not more than two degrees. A significant error will be introduced in the calculation when the artificial horizontal rock surface is assumed in the soil layer according to the shear velocity of the soil media. The elasticity of the solid rock has little influence on the seismic response of the deep soil layer. The field investigation on the soil dynamic property should be paid more attention to.

关键词: little influence     layer     calculation     Shanghai     dynamic    

Factors affecting the formation of zeolite seed layers and the effects of seed layers on the growth of

ZHANG Xiongfu, WANG Jinqu, LIU Hai′ou, WANG Anjie

《化学科学与工程前沿(英文)》 2007年 第1卷 第2期   页码 172-177 doi: 10.1007/s11705-007-0032-6

摘要: The present study investigates the formation of silicalite-1 seed layers on a porous carbon support of 0.5 μm pore size and α-A1O supports with different pore sizes (0.1 μm and 4 μm) via the slip-casting technique. The effects of support property, seed size and solvent on the formation of seed layers were investigated in detail. The growth of silicalite-1 membranes on different seeded supports by hydrothermal synthesis was also evaluated. The scanning electron microscopy (SEM) and X-ray diffraction (XRD) characterizations indicate that a continuous seed layer can be obtained on the smooth support of 0.1 μm pore size by using any seed of 100 nm, 600 nm or 2.2 μm in size, whereas, on the coarse supports with either 0.5 μm or 4 μm pore size, a continuous seed layer cannot be formed using the above seed sizes and the same seeding time. At a longer contact time, a seed layer can also be formed using 100 nm seed on the supports with larger pore size. However, the layer is not uniform and smooth. For a hydrophobic porous carbon support, seeding ethanol suspension, which has weak polarity, favors the formation of a continuous seed layer. The seed layers and membranes grown from the smaller seed are more uniform and continuous and possess smoother surfaces than those from the larger seed. The seed layer and respective grown membrane formed from nanosized seed (100 nm) are the most uniform and compact. With this method of seeded secondary synthesis of zeolite membranes, the quality of a membrane mainly depends on the quality of the seed layer.

关键词: silicalite-1     α-A1O     growth     seeding ethanol     quality    

Solvent-resistant porous membranes using poly(ether−ether ketone): preparation and application

《化学科学与工程前沿(英文)》 2023年 第17卷 第10期   页码 1536-1559 doi: 10.1007/s11705-022-2221-8

摘要: Poly(ether−ether ketone) (PEEK) is a linear aromatic macromolecule, which can form semi-crystalline aggregative status, allowing PEEK materials to have strong environment tolerance and excellent physicochemical properties. PEEK materials have become a promising alternative to fabricate particular membranes used in extreme conditions. In the past few decades, many researches and evolutions have emerged in membrane fabrication with PEEK materials and its applications for treating organic solvents and their mixtures; however, there are little systematic and comprehensive literature to summarize fabrication approaches, compile applications, and elaborate PEEK property-structure relationship. In this review, the main approaches to fabricate PEEK-based membranes are illustrated concretely, including conventional thermal-induced and non-solvent-induced phase separation, and novel chemical-induced crystallization; the representative applications in ultrafiltration, nanofiltration and membrane contactor containing organic solvents are demonstrated systematically. Meanwhile, the mechanism to tune PEEK solubility in solvents, which can be achieved by altering monomers in synthesis processes or changing membrane preparation routes, is deeply analyzed. Moreover, the existing problems and the future prospects are also discussed. This review provides positive guidance for designing and fabricating membranes using PEEK and its derivative materials for task-specific applications in harsh conditions.

关键词: PEEK     phase inversion     solvent-resistant membrane     nanofiltration     membrane contactor    

Modeling of dynamic response of poroelastic soil layers under wave loading

Mehmet Bar?? Can üLKER

《结构与土木工程前沿(英文)》 2014年 第8卷 第1期   页码 1-18 doi: 10.1007/s11709-014-0233-2

摘要: In this paper, the dynamic response of saturated and layered soils under harmonic waves is modeled using the finite element method. The numerical results are then verified by corresponding analytical solutions which are also developed by the author. The equations governing the dynamics of porous media are written in their fully dynamic form and possible simplifications are introduced based on the presence of inertial terms associated with solid and fluid phases. The response variations are presented in terms of pore water pressure and shear stress distributions within the layers. It is determined that a set of non-dimensional parameters and their respective ratios as a result of layering play a major role in the dynamic response.

关键词: dynamic response of soils     coupled flow-deformation     finite elements     analytical solution     harmonic waves    

Modification of premixed combustion in shear layers by grid turbulence

MU Kejin, WANG Yue, ZHANG Zhedian, NIE Chaoqun

《能源前沿(英文)》 2007年 第1卷 第2期   页码 245-250 doi: 10.1007/s11708-007-0034-6

摘要: The influence of grid turbulence on the shear layer of a jet and the premixed flames embedded in it was investigated in the present study. The velocity field of the jet was measured by using hot-wire anemometry. It was found that grid turbulence reduced turbulence intensities in the shear layer and suppressed low frequency fluctuation. Moreover, the energy contained in small-scale fluctuation was increased and turbulence became homogeneous. The results indicate that grid turbulence inhibits the formation of a large-scale coherent structure in the shear layer. Flame temperature was measured by using a compensated fine-wire thermocouple. It was found that grid turbulence reduced low frequency fluctuation of the flame fronts, increased the small-scale wrinkles and elevated the mean temperature of the flame zone. The results show that grid turbulence can enhance and stabilize premixed flames in shear flow.

关键词: homogeneous     fine-wire thermocouple     temperature     hot-wire anemometry     premixed    

Identification of resistant pharmaceuticals in ozonation using QSAR modeling and their fate in electro-peroxone

《环境科学与工程前沿(英文)》 2021年 第15卷 第5期 doi: 10.1007/s11783-021-1394-6

摘要:

• Effect of converting ozonation to E-peroxone was studied on pharmaceutical removal.

关键词: Ozone     Electro-peroxone     Wastewater     Quantitative structure activity relationship     Advanced oxidation processes    

Rapamycin enhances the anti-tumor activity of cabozantinib in cMet inhibitor-resistant hepatocellular

《医学前沿(英文)》 2022年 第16卷 第3期   页码 467-482 doi: 10.1007/s11684-021-0869-y

摘要: Cabozantinib, mainly targeting cMet and vascular endothelial growth factor receptor 2, is the second-line treatment for patients with advanced hepatocellular carcinoma (HCC). However, the lower response rate and resistance limit its enduring clinical benefit. In this study, we found that cMet-low HCC cells showed primary resistance to cMet inhibitors, and the combination of cabozantinib and mammalian target of rapamycin (mTOR) inhibitor, rapamycin, exhibited a synergistic inhibitory effect on the in vitro cell proliferation and in vivo tumor growth of these cells. Mechanically, the combination of rapamycin with cabozantinib resulted in the remarkable inhibition of AKT, extracellular signal-regulated protein kinases, mTOR, and common downstream signal molecules of receptor tyrosine kinases; decreased cyclin D1 expression; and induced cell cycle arrest. Meanwhile, rapamycin enhanced the inhibitory effects of cabozantinib on the migration and tubule formation of human umbilical vascular endothelial cells and human growth factor-induced invasion of cMet inhibitor-resistant HCC cells under hypoxia condition. These effects were further validated in xenograft models. In conclusion, our findings uncover a potential combination therapy of cabozantinib and rapamycin to combat cabozantinib-resistant HCC.

关键词: hepatocellular carcinoma     cabozantinib     primary resistance     rapamycin    

Effect of a promoter on the methanation activity of a Mo-based sulfur-resistant catalyst

Can LIN, Haiyang WANG, Zhenhua LI, Baowei WANG, Xinbin MA, Shaodong QIN, Qi SUN

《化学科学与工程前沿(英文)》 2013年 第7卷 第1期   页码 88-94 doi: 10.1007/s11705-013-1301-1

摘要: The effect of adding Co, Ni or La on the methanation activity of a Mo-based sulfur-resistant catalyst was investigated. As promoters, Co, Ni and La all improved the methanation activity of a 15% MoO /Al O catalyst but to different extents. Similar improvements were also found when Co, Ni or La was added to a 15% MoO /25%-CeO -Al O catalyst. The promotion effects of Co and Ni were better than that of La. However, the catalytic methanation activity deteriorated the most with time for the Ni-promoted catalyst. The used catalysts were analyzed by nitrogen adsorption measurement, X-ray diffraction and X-ray photoelectron spectroscopy.

关键词: sulfur-resistant     methanation     promoter    

Screening responsive or resistant biomarkers of immune checkpoint inhibitors based on online databases

Zhen Xiang, Yingyan Yu

《医学前沿(英文)》 2019年 第13卷 第1期   页码 24-31 doi: 10.1007/s11684-019-0679-7

摘要: Immune checkpoint inhibitors are a promising strategy in the treatment of cancer, especially advanced types. However, not all patients are responsive to immune checkpoint inhibitors. The response rate depends on the immune microenvironment, tumor mutational burden (TMB), expression level of immune checkpoint proteins, and molecular subtypes of cancers. Along with the Cancer Genome Project, various open access databases, including The Cancer Genome Atlas and Gene Expression Omnibus, provide large volumes of data, which allow researchers to explore responsive or resistant biomarkers of immune checkpoint inhibitors. In this review, we introduced some methodologies on database selection, biomarker screening, current progress of immune checkpoint blockade in solid tumor treatment, possible mechanisms of drug resistance, strategies of overcoming resistance, and indications for immune checkpoint inhibitor therapy.

关键词: immune checkpoint blockade     sensitivity     resistance     data mining    

Effect of ultraviolet irradiation and chlorination on ampicillin-resistant

Yuchen PANG,Jingjing HUANG,Jinying XI,Hongying HU,Yun ZHU

《环境科学与工程前沿(英文)》 2016年 第10卷 第3期   页码 522-530 doi: 10.1007/s11783-015-0779-9

摘要: Antibiotic resistance is a serious public health risk that may spread via potable and reclaimed water. Effective disinfection is important for inactivation of antibiotic-resistant bacteria and disruption of antibiotic resistance genes. Ampicillin is a widely prescribed antibiotic but its effectiveness is increasingly undermined by resistance. In this study, changes in ampicillin resistance for ( ) CGMCC 1.1595 were analyzed after exposure to different doses of ultraviolet (UV) or chlorine, and damage incurred by the plasmid encoding ampicillin resistance gene was assessed. We reported a greater stability in ampicillin-resistant CGMCC 1.1595 after UV irradiation or chlorination when compared with previously published data for other strains. UV irradiation and chlorination led to a shift in the mortality frequency distributions of ampicillin-resistant when subsequently exposed to ampicillin. The ampicillin hemi-inhibitory concentration (IC ) without disinfection was 3800 mg·L , and an increment was observed after UV irradiation or chlorination. The IC of ampicillin-resistant was 1.5-fold higher at a UV dose of 40 mJ·cm , and was 1.4-fold higher when exposed to 2.0 mg·L chlorine. These results indicate that UV irradiation and chlorination can potentially increase the risk of selection for strains with high ampicillin resistance. There was no evident damage to after 1–10 mg Cl ·L chlorination, while a UV dose of 80 mJ·cm yielded a damage ratio for of approximately 1.2-log. Therefore, high UV doses are required for effective disruption of antibiotic resistance genes in bacteria.

关键词: antibiotic resistance     Escherichia coli     ampicillin resistance gene     ultraviolet irradiation     chlorination    

Presence, dissemination and removal of antibiotic resistant bacteria and antibiotic resistance genes

Qiaowen Tan, Weiying Li, Junpeng Zhang, Wei Zhou, Jiping Chen, Yue Li, Jie Ma

《环境科学与工程前沿(英文)》 2019年 第13卷 第3期 doi: 10.1007/s11783-019-1120-9

摘要:

Reviewed the change of ARGs and ARB in full-scale urban drinking water systems.

Conventional processes are more promising than BAC process in ARGs removal.

Mechanisms of ARGs enrichment and spread in BAC filter and DWDSs are discussed.

Raise the need of future research on ARGs and ARB change in building plumbing systems.

关键词: Antibiotic resistant bacteria     Antibiotic resistance genes     Water source     Drinking water treatment plant     Drinking water distribution system     Urban drinking water system    

Surface-tailoring chlorine resistant materials and strategies for polyamide thin film composite reverse

《化学科学与工程前沿(英文)》 2022年 第16卷 第5期   页码 564-591 doi: 10.1007/s11705-021-2109-z

摘要: Polyamide thin film composite membranes have dominated current reverse osmosis market on account of their excellent separation performances compared to the integrally skinned counterparts. Despite their very promising separation performance, chlorine-induced degradation resulted from the susceptibility of polyamide toward chlorine attack has been regarded as the Achilles’s heel of polyamide thin film composite. The free chlorine species present during chlorine treatment can impair membrane performance through chlorination and depolymerization of the polyamide selective layer. From material point of view, a chemically stable membrane is crucial for the sustainable application of membrane separation process as it warrants a longer membrane lifespan and reduces the cost involved in membrane replacement. Various strategies, particularly those involved membrane material optimization and surface modifications, have been established to address this issue. This review discusses membrane degradation by free chlorine attack and its correlation with the surface chemistry of polyamide. The advancement in the development of chlorine resistant polyamide thin film composite membranes is reviewed based on the state-of-the-art surface modifications and tailoring approaches which include the in situ and post-fabrication membrane modifications using a broad range of functional materials. The challenges and future directions in this field are also highlighted.

关键词: reverse osmosis     polyamide     thin film composite membranes     chlorine resistance     surface modification    

Vehicle roll stability control with active roll-resistant electro-hydraulic suspension

Lijun XIAO, Ming WANG, Bangji ZHANG, Zhihua ZHONG

《机械工程前沿(英文)》 2020年 第15卷 第1期   页码 43-54 doi: 10.1007/s11465-019-0547-9

摘要: This study examines roll stability control for vehicles with an active roll-resistant electro-hydraulic suspension (RREHS) subsystem under steering maneuvers. First, we derive a vehicle model with four degrees of freedom and incorporates yaw and roll motions. Second, an optimal linear quadratic regulator controller is obtained in consideration of dynamic vehicle performance. Third, an RREHS subsystem with an electric servo-valve actuator is proposed, and the corresponding dynamic equations are obtained. Fourth, field experiments are conducted to validate the performance of the vehicle model under sine-wave and double-lane-change steering maneuvers. Finally, the effectiveness of the active RREHS is determined by examining vehicle responses under sine-wave and double-lane-change maneuvers. The enhancement in vehicle roll stability through the RREHS subsystem is also verified.

关键词: electro-hydraulic suspension     roll stability     LQR     experiment    

标题 作者 时间 类型 操作

Research on the method of cavitations resistance in a piezoelectric pump with 3-dimensional mesh structure

ZHANG Jian-hui, Bai Heng-jun, XIA Qi-xiao, NING Hong-gang, ONUKI Akiyoshi

期刊论文

Crushed rocks stabilized with organosilane and lignosulfonate in pavement unbound layers: Repeated load

Diego Maria BARBIERI, Inge HOFF, Chun-Hsing HO

期刊论文

Analyses of the seismic responses of soil layers with deep deposits

LOU Menglin, LI Yuchun, LI Nansheng

期刊论文

Factors affecting the formation of zeolite seed layers and the effects of seed layers on the growth of

ZHANG Xiongfu, WANG Jinqu, LIU Hai′ou, WANG Anjie

期刊论文

Solvent-resistant porous membranes using poly(ether−ether ketone): preparation and application

期刊论文

Modeling of dynamic response of poroelastic soil layers under wave loading

Mehmet Bar?? Can üLKER

期刊论文

Modification of premixed combustion in shear layers by grid turbulence

MU Kejin, WANG Yue, ZHANG Zhedian, NIE Chaoqun

期刊论文

Identification of resistant pharmaceuticals in ozonation using QSAR modeling and their fate in electro-peroxone

期刊论文

Rapamycin enhances the anti-tumor activity of cabozantinib in cMet inhibitor-resistant hepatocellular

期刊论文

Effect of a promoter on the methanation activity of a Mo-based sulfur-resistant catalyst

Can LIN, Haiyang WANG, Zhenhua LI, Baowei WANG, Xinbin MA, Shaodong QIN, Qi SUN

期刊论文

Screening responsive or resistant biomarkers of immune checkpoint inhibitors based on online databases

Zhen Xiang, Yingyan Yu

期刊论文

Effect of ultraviolet irradiation and chlorination on ampicillin-resistant

Yuchen PANG,Jingjing HUANG,Jinying XI,Hongying HU,Yun ZHU

期刊论文

Presence, dissemination and removal of antibiotic resistant bacteria and antibiotic resistance genes

Qiaowen Tan, Weiying Li, Junpeng Zhang, Wei Zhou, Jiping Chen, Yue Li, Jie Ma

期刊论文

Surface-tailoring chlorine resistant materials and strategies for polyamide thin film composite reverse

期刊论文

Vehicle roll stability control with active roll-resistant electro-hydraulic suspension

Lijun XIAO, Ming WANG, Bangji ZHANG, Zhihua ZHONG

期刊论文