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Proteins moonlighting in tumor metabolism and epigenetics
Lei Lv, Qunying Lei
《医学前沿(英文)》 2021年 第15卷 第3期 页码 383-403 doi: 10.1007/s11684-020-0818-1
Vanadium metabolism investigation using substance flow and scenario analysis
Fangfang ZHANG, Huiquan LI, Bo CHEN, Xue GUAN, Yi ZHANG
《环境科学与工程前沿(英文)》 2014年 第8卷 第2期 页码 256-266 doi: 10.1007/s11783-013-0585-1
关键词: metabolism vanadium industry substance flow analysis scenario analysis
Insulin resistance and the metabolism of branched-chain amino acids
null
《医学前沿(英文)》 2013年 第7卷 第1期 页码 53-59 doi: 10.1007/s11684-013-0255-5
Insulin resistance (IR) is a key pathological feature of metabolic syndrome and subsequently causes serious health problems with an increased risk of several common metabolic disorders. IR related metabolic disturbance is not restricted to carbohydrates but impacts global metabolic network. Branched-chain amino acids (BCAAs), namely valine, leucine and isoleucine, are among the nine essential amino acids, accounting for 35% of the essential amino acids in muscle proteins and 40% of the preformed amino acids required by mammals. The BCAAs are particularly responsive to the inhibitory insulin action on amino acid release by skeletal muscle and their metabolism is profoundly altered in insulin resistant conditions and/or insulin deficiency. Although increased circulating BCAA concentration in insulin resistant conditions has been noted for many years and BCAAs have been reported to be involved in the regulation of glucose homeostasis and body weight, it is only recently that BCAAs are found to be closely associated with IR. This review will focus on the recent findings on BCAAs from both epidemic and mechanistic studies.
关键词: branched-chain amino acids leucine isoleucine valine insulin resistance
Jingyue Zhang, Yawen Song, Qianqian Shi, Li Fu
《医学前沿(英文)》 2021年 第15卷 第5期 页码 649-656 doi: 10.1007/s11684-021-0830-0
Dawen Gao, Xiaolong Wang, Hong Liang, Qihang Wei, Yuan Dou, Longwei Li
《环境科学与工程前沿(英文)》 2018年 第12卷 第3期 doi: 10.1007/s11783-018-1035-x
关键词: Anammox Metabolism Metagenome Ecological distribution Microbial interactions
Metabolism and immunity in breast cancer
Deyu Zhang, Xiaojie Xu, Qinong Ye
《医学前沿(英文)》 2021年 第15卷 第2期 页码 178-207 doi: 10.1007/s11684-020-0793-6
Weihua ZENG,Bo WU,Ying CHAI
《环境科学与工程前沿(英文)》 2016年 第10卷 第1期 页码 114-128 doi: 10.1007/s11783-014-0669-6
关键词: urban water metabolism system (UWMS) system dynamic simulation water environmental carrying capacity (WECC) feedback loops bilateral control
Expression profiles of genes and enzymes related to ascorbic acid metabolism in fruits of
Yingying CHEN,Zhihui ZHAO,Jin ZHAO,Mengjun LIU
《农业科学与工程前沿(英文)》 2016年 第3卷 第2期 页码 131-136 doi: 10.15302/J-FASE-2016096
《医学前沿(英文)》 2023年 第17卷 第1期 页码 119-131 doi: 10.1007/s11684-022-0949-7
关键词: GDF15 esophageal squamous cell carcinoma chemoresistance cellular metabolism TGFBR2 AKT
Zooming in and out of ferroptosis in human disease
《医学前沿(英文)》 2023年 第17卷 第2期 页码 173-206 doi: 10.1007/s11684-023-0992-z
关键词: ferroptosis human disease iron metabolism lipid peroxidation antioxidation
Water-dispersible nano-pollutions reshape microbial metabolism in type-specific manners: A metabolic
《环境科学与工程前沿(英文)》 2022年 第16卷 第9期 doi: 10.1007/s11783-022-1548-1
• Water-dispersible nano-pollutions exhibit type-specific toxic effects on E. coli.
关键词: Nano-toxicity Nano-plastics Quantum dots Microbial metabolite Metabolic dysregulation
The MYC transcription factor network: balancing metabolism, proliferation and oncogenesis
null
《医学前沿(英文)》 2018年 第12卷 第4期 页码 412-425 doi: 10.1007/s11684-018-0650-z
Transcription factor networks have evolved in order to control, coordinate, and separate, the functions of distinct network modules spatially and temporally. In this review we focus on the MYC network (also known as the MAX-MLX Network), a highly conserved super-family of related basic-helix-loop-helix-zipper (bHLHZ) proteins that functions to integrate extracellular and intracellular signals and modulate global gene expression. Importantly the MYC network has been shown to be deeply involved in a broad spectrum of human and other animal cancers. Here we summarize molecular and biological properties of the network modules with emphasis on functional interactions among network members. We suggest that these network interactions serve to modulate growth and metabolism at the transcriptional level in order to balance nutrient demand with supply, to maintain growth homeostasis, and to influence cell fate. Moreover, oncogenic activation of MYC and/or loss of a MYC antagonist, results in an imbalance in the activity of the network as a whole, leading to tumor initiation, progression and maintenance.
Multi-omics joint analysis revealed the metabolic profile of retroperitoneal liposarcoma
《医学前沿(英文)》 doi: 10.1007/s11684-023-1020-z
Gang GUO, Yayi WANG, Chong WANG, Hong WANG, Mianli PAN, Shaowei CHEN
《环境科学与工程前沿(英文)》 2013年 第7卷 第4期 页码 616-624 doi: 10.1007/s11783-013-0505-4
关键词: Denitrifying phosphorus removal anaerobic reaction time nitrous oxide polyhydroxyalkanoate free nitrous acid fluorescence in-situ hybridization
XU Leping, JI Juying, DUAN Yiyang, SHI Hui, ZHANG Bin, SHAO Yaqin, SUN Jian
《医学前沿(英文)》 2007年 第1卷 第3期 页码 316-319 doi: 10.1007/s11684-007-0061-z
关键词: significant difference occurrence hemoglobin risperidone treatment abnormal
标题 作者 时间 类型 操作
Vanadium metabolism investigation using substance flow and scenario analysis
Fangfang ZHANG, Huiquan LI, Bo CHEN, Xue GUAN, Yi ZHANG
期刊论文
Research progress on FASN and MGLL in the regulation of abnormal lipid metabolism and the relationship
Jingyue Zhang, Yawen Song, Qianqian Shi, Li Fu
期刊论文
Anaerobic ammonia oxidizing bacteria: ecological distribution, metabolism, and microbial interactions
Dawen Gao, Xiaolong Wang, Hong Liang, Qihang Wei, Yuan Dou, Longwei Li
期刊论文
Dynamic simulation of urban water metabolism under water environmental carrying capacity restrictions
Weihua ZENG,Bo WU,Ying CHAI
期刊论文
Expression profiles of genes and enzymes related to ascorbic acid metabolism in fruits of
Yingying CHEN,Zhihui ZHAO,Jin ZHAO,Mengjun LIU
期刊论文
GDF15 negatively regulates chemosensitivity via TGFBR2-AKT pathway-dependent metabolism in esophageal
期刊论文
Water-dispersible nano-pollutions reshape microbial metabolism in type-specific manners: A metabolic
期刊论文
Short-term effects of excessive anaerobic reaction time on anaerobic metabolism of denitrifying polyphosphate
Gang GUO, Yayi WANG, Chong WANG, Hong WANG, Mianli PAN, Shaowei CHEN
期刊论文