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A better way to do small-for-size liver transplantation in rats
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《医学前沿(英文)》 2011年 第5卷 第1期 页码 106-110 doi: 10.1007/s11684-011-0113-2
Establishing a model for small-for-size liver transplantation is the basis for this study of partial and living donor graft liver transplantation. This study aims to explore a simpler and more effective way of establishing a 30% small-for-size liver transplantation in rats. Sprague-Dawley rats were selected as the donors and recipients. Small-for-size orthotopic liver transplantation was performed using Kamada’s two-cuff method. The donor’s liver was flushed via the abdominal aorta and hepatectomy was performed in situ. The animals were divided into three groups depending on the graft selected, with 40 pairs of rats in each group. In group I, the median lobe of the liver was used as graft; in group II, the right half of the median lobe and the right lobe were used as graft; and in group III, the median and right lobes were used as graft. In groups I and II, the bodyweights of donors were the same as those of recipients; however, in group III the bodyweights of donors were 100–120 g less than those of the recipients. The duration needed for transplantation, the 7-day survival rates, and the technical complication rates were compared among these three groups. The time required for hepatectomy was shorter in group III compared with groups I and II (8.8?±?0.7 min vs. 11.5?±?1.1 min and 10.1?±?1.0 min, P = 0.001). The cold ischemia time for the grafts, the anhepatic times, and the transplantation times for the recipients were not significantly different among the three groups. Compared with groups I and II, the incidence of bleeding, bile leakage, and inferior vena caval strictures were significantly decreased in group III (P<0.05). No significant differences between the three groups were found based on other complications after the operation (P>0.05). Group III had better 7-day survival rates and longer median survival times but the differences were not statistically significant. The method of small for donor bodyweight using the median and right lobes for grafting may be a more effective and simpler way of establishing a 30% small-for-size liver transplantation in rats, as shown by the shorter hepatectomy time and the occurrence of fewer complications after the operation.
Experimental measurement of double-K fracture parameters of concrete with small-size aggregates
ZHANG Xiufang, XU Shilang, ZHENG Shuang
《结构与土木工程前沿(英文)》 2007年 第1卷 第4期 页码 448-457 doi: 10.1007/s11709-007-0061-8
Wentao WANG, Chongzhi TU, Rong LUO
《结构与土木工程前沿(英文)》 2018年 第12卷 第4期 页码 568-576 doi: 10.1007/s11709-017-0444-4
关键词: sand embankment compaction in large thickness numerical simulation small size vibratory roller steady compaction
基于Wasserstein GAN的新一代人工智能小样本数据增强方法——以生物领域癌症分期数据为例 Article
刘宇飞, 周源, 刘欣, 董放, 王畅, 王子鸿
《工程(英文)》 2019年 第5卷 第1期 页码 156-163 doi: 10.1016/j.eng.2018.11.018
以大数据为基础的深度学习算法在推动新一代人工智能快速发展中意义重大。然而深度学习的有效利用对标注样本数量的高度依赖,使得深度学习在小样本数据环境下的应用受到制约。本研究提出了一种基于生成对抗网络(generative adversarial network,GAN)和深度神经网络(deep neural network,DNN)分类器的方法。首先,将原始样本划分为训练集样本和测试集样本,采用训练集样本训练GAN 后生成模拟样本数据,扩增训练集样本规模;然后,使用模拟样本训练DNN 分类器;最后,使用测试集样本测试分类器,并通过指标验证该方法在小样本多分类问题下的有效性。作为实证案例,将该方法应用于生物领域癌症分期识别,结果表明该方法比传统方法获得更高的识别准确率。同时,该方法是一次将基于原始样本的经典统计机器学习分类方法转变为基于数据增强的深度学习分类方法的尝试。本研究有助于探索以深度学习为代表的新一代人工智能技术在应用范围与应用效果方面的潜力。这将对各领域全面推进新一代人工智能的发展具有重要意义。
《环境科学与工程前沿(英文)》 2021年 第15卷 第3期 doi: 10.1007/s11783-020-1356-4
•Bacterial concentrations from eight stages were 104–105copies/m3.
关键词: Size distribution Airborne bacteria Biological diversity Human pathogenic bacteria Composting plants
A ruptured recurrent small bowel gastrointestinal stromal tumour causing hemoperitoneum
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《医学前沿(英文)》 2015年 第9卷 第1期 页码 108-111 doi: 10.1007/s11684-014-0344-0
Hemoperitoneum is a rare and potentially life-threatening complication of GIST. We reported a 54-year-old man who developed disseminated intra-abdominal recurrence from a previously resected gastrointestinal stromal tumour (GIST) of the small bowel, and the patient presented with hemoperitoneum. Emergent debulking surgery was performed. A high dose imatinib was prescribed. Despite the presence of residual disease, the patient was well clinically 8 months after the operation. Even though, there is no evidence to support the routine use of debulking surgery in the management of GIST. In our patient, disease progression after second line targeted therapy and the absence of alternative treatment options for spontaneous rupture and hemoperitoneum prompted us to treat the patient aggressively. Resection of the ruptured GIST was carried out for control of bleeding and to prevent recurrent bleeding in this patient with good surgical risks. During the treatment decision-making, the patient’s general condition, the risk of surgery and the extent of dissemination were taken into consideration. In this patient who presented with spontaneous rupture of a small intestinal GIST, the novel use of targeted therapy and aggressive surgical treatment produced reasonably good survival outcome.
关键词: gastrointestinal stromal tumour hemoperitoneum small bowel GIST small bowel neoplasm imatinib
Particle size distribution and shape control of Au nanoparticles used for particle gun
S. Kida, M. Ichiji, J. Watanabe, I. Hirasawa
《化学科学与工程前沿(英文)》 2013年 第7卷 第1期 页码 60-64 doi: 10.1007/s11705-013-1313-x
关键词: reduction crystallization particle size distribution gene transferring media
《环境科学与工程前沿(英文)》 2022年 第16卷 第10期 doi: 10.1007/s11783-022-1557-0
● A series of Cu-ZSM-5 catalysts were tested for DMF selective catalytic oxidation.
关键词: N N-Dimethylformamide Selective catalytic oxidation Cu-ZSM-5 CuO particle size
Simulation and experimental improvement on a small-scale Stirling thermo-acoustic engine
Mao CHEN,Yonglin JU
《能源前沿(英文)》 2016年 第10卷 第1期 页码 37-45 doi: 10.1007/s11708-015-0390-6
关键词: thermo-acoustic Stirling engine small-scale simulation experiment
Discovery of small molecule degraders for modulating cell cycle
《医学前沿(英文)》 页码 823-854 doi: 10.1007/s11684-023-1027-5
《结构与土木工程前沿(英文)》 页码 1163-1187 doi: 10.1007/s11709-023-0987-5
关键词: cast-in anchor concrete cone capacity geopolymer concrete head size surface crack anchor profile
Fine-tuning cell organelle dynamics during mitosis by small GTPases
《医学前沿(英文)》 2022年 第16卷 第3期 页码 339-357 doi: 10.1007/s11684-022-0926-1
Gut microbiota and its implications in small bowel transplantation
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《医学前沿(英文)》 2018年 第12卷 第3期 页码 239-248 doi: 10.1007/s11684-018-0617-0
The gut microbiota is mainly composed of a diverse population of commensal bacterial species and plays a pivotal role in the maintenance of intestinal homeostasis, immune modulation and metabolism. The influence of the gut microbiota on solid organ transplantation has recently been recognized. In fact, several studies indicated that acute and chronic allograft rejection in small bowel transplantation (SBT) is closely associated with the alterations in microbial patterns in the gut. In this review, we focused on the recent findings regarding alterations in the microbiota following SBT and the potential roles of these alterations in the development of acute and chronic allograft rejection. We also reviewed important advances with respect to the interplays between the microbiota and host immune systems in SBT. Furthermore, we explored the potential of the gut microbiota as a microbial marker and/or therapeutic target for the predication and intervention of allograft rejection and chronic dysfunction. Given that current research on the gut microbiota has become increasingly sophisticated and comprehensive, large cohort studies employing metagenomic analysis and multivariate linkage should be designed for the characterization of host–microbe interaction and causality between microbiota alterations and clinical outcomes in SBT. The findings are expected to provide valuable insights into the role of gut microbiota in the development of allograft rejection and other transplant-related complications and introduce novel therapeutic targets and treatment approaches in clinical practice.
关键词: gut microbiota small bowel transplantation acute rejection chronic rejection mucosal immunity biomarker microbiota-targeted therapy
Effect of particle size on coal char----NO reaction
Xiumin JIANG, Xiangyong HUANG, Jiaxun LIU, Chaoqun ZHANG
《能源前沿(英文)》 2011年 第5卷 第2期 页码 221-228 doi: 10.1007/s11708-011-0146-x
关键词: NO reduction chemisorption particle size X-ray photoelectron spectroscopy density functional theory (DFT)
Soot size distribution in lightly sooting premixed flames of benzene and toluene
Wang LIU, Jiaqi ZHAI, Baiyang LIN, He LIN, Dong HAN
《能源前沿(英文)》 2020年 第14卷 第1期 页码 18-26 doi: 10.1007/s11708-020-0663-6
关键词: premixed flame soot particle size distribution function benzene toluene
标题 作者 时间 类型 操作
Experimental measurement of double-K fracture parameters of concrete with small-size aggregates
ZHANG Xiufang, XU Shilang, ZHENG Shuang
期刊论文
Numerical simulation of compaction parameters for sand-filled embankment using large thickness sand filling technique in Jianghan Plain district
Wentao WANG, Chongzhi TU, Rong LUO
期刊论文
The size distribution of airborne bacteria and human pathogenic bacteria in a commercial composting plant
期刊论文
Particle size distribution and shape control of Au nanoparticles used for particle gun
S. Kida, M. Ichiji, J. Watanabe, I. Hirasawa
期刊论文
Effect of Cu-ZSM-5 catalysts with different CuO particle size on selective catalytic oxidation of N,N-Dimethylformamide
期刊论文
Simulation and experimental improvement on a small-scale Stirling thermo-acoustic engine
Mao CHEN,Yonglin JU
期刊论文
Influence of surface cracking, anchor head profile, and anchor head size on cast-in headed anchors in
期刊论文
Effect of particle size on coal char----NO reaction
Xiumin JIANG, Xiangyong HUANG, Jiaxun LIU, Chaoqun ZHANG
期刊论文