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Effects of miR-200c on the migration and invasion abilities of human prostate cancer Du145 cells and

Runlin Shi,Haibing Xiao,Tao Yang,Lei Chang,Yuanfeng Tian,Bolin Wu,Hua Xu

Frontiers of Medicine 2014, Volume 8, Issue 4,   Pages 456-463 doi: 10.1007/s11684-014-0353-z

Abstract: This study aimed to investigate the effects of miRNA-200c (miR-200c) on the biological behavior and mechanismIn this study, Du145 cells were transfected with miR-200c mimics or negative control miR-NC by usingThe relative expression of miR-200c was measured by RT-PCR.Du145 cells were then transfected with miR-200c mimics and displayed lower abilities of proliferationlikewise, miR-200c could inhibit migration and invasion by epithelial-mesenchymal transition.

Keywords： miR-200c     proliferation     migration     invasion     prostate cancer     Du145 cell     ZEB1    

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The microRNA, miR-29c, participates in muscle development through targeting the

Weiya ZHANG,Wei WEI,Yuanyuan ZHAO,Shuhong ZHAO,Xinyun LI

Frontiers of Agricultural Science and Engineering 2015, Volume 2, Issue 4,   Pages 311-317 doi: 10.15302/J-FASE-2015075

Abstract: Previous studies indicated that miR-29c is important for muscle development in mice and human, but itsIn this study, we detected the expression of miR-29c in Meishan longissimus lumborum (LL) muscle.The results showed that miR-29c was gradually upregulated during development of skeletal muscle in pigMoreover, the expression of and genes, which were confirmed to be targeted by miR-29c in mice, wasIn addition, we identified a T to C mutation in the primary transcript of miR-29c, which was associated

Keywords： pig     miR-29c     skeletal muscle     expression     SNP    

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200 km Per Hour一The Best Choice for Beijing - Shanghai Express Railway

Li Yushan

Strategic Study of CAE 2004, Volume 6, Issue 12,   Pages 7-12

Abstract: The paper maintains that the electrified fast-speed wheel/rail system with a speed of 200 km per hour

Keywords： Beijing - Shanghai express railway     optimal choice     maglev     high-speed rail system     fast-speed rail system    

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The expression mode of hsa-miR-197 in uterine leiomyomas tissue and related bioinformatics analysis

Xu Qing,Fu Ziyi,Wu Xiaoli,Huangfu Yushuang and Ling Jing

Strategic Study of CAE 2014, Volume 16, Issue 5,   Pages 99-104

Abstract:

We performed Real-time PCR to detect the hsa-miR-197 expression levelsmiRbase，UCSC，NCBI are employed to analysis the sequence conservation and genetic characteristics of hsa- miR- 197；miRNA databases such as miRanda，MirTarget2 and TargetScan are chosen to predict hsa- miR- 197 targetchosen，and GO and Pathway analysis of these genes are carried out to explore the potential role of hsa-miR-197 playing in regulating the uterine leiomyomas occurrence and development. hsa-miR-197 functions in

Keywords： uterine leiomyomas     hsa-miR-197     bioinformatics analysis     target genes    

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Overexpressed miR-9 promotes tumor metastasis via targeting E-cadherin in serous ovarian cancer

Bo Zhou, Hongbin Xu, Meng Xia, Chaoyang Sun, Na Li, Ensong Guo, Lili Guo, Wanying Shan, Hao Lu, Yifan Wu, Yuan Li, Degui Yang, Danhui Weng, Li Meng, Junbo Hu, Ding Ma, Gang Chen, Kezhen Li

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 214-222 doi: 10.1007/s11684-017-0518-7

Abstract: Dysfunctional miR-9 expression remains ambiguous, and no consensus on the metastatic progression of ovarianbioinformatics analysis show that the 3′-UTR of the E-cadherin mRNA was directly regulated by miRLuciferase reporter assay results confirmed that miR-9 could directly target this 3′-UTR. miR-9Upregulation of miR-9 could downregulate the expression of E-cadherin but upregulate the expression ofcould be effectively inhibited via miR-9 inhibitor.

Keywords： ovarian cancer     metastasis     miR-9     E-cadherin    

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-Derived miR162a Functions on Osteoporosis Through Directly Promoting Osteoblast Formation

Chunyan Gu,Xichao Yu,Xiaozhu Tang,Leilei Gong,Jingquan Tan,Yuanjiao Zhang,Huili Zheng,Ze Wang,Chenqian Zhang,Yejin Zhu,Zuojian Zhou,Heming Yu,Kai Xu,Jinao Duan,Xiaosong Gu,Ye Yang,

Engineering doi: 10.1016/j.eng.2023.09.007

Abstract: Illumina deep sequencing analysis and stem-loop polymerase chain reaction (PCR) assay revealed that miR162aImmunofluorescence staining showed that miR162a was absorbed through systemic RNA interference defectiveBioinformatics prediction and luciferase reporter assay identified that miR162a targeted nuclear receptorAlizarin red staining and micro-computed tomography (microCT) confirmed that miR162a promoted osteogenicIn addition, transgenic Nicotiana benthamiana (N. benthamiana) leaves overexpressing miR162a were developed

Keywords： Traditional Chinese medicine     Lycium barbarum     L     miR162a     Osteoporosis     Nuclear receptor corepressor     Transgenic    

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Correlation between serum miR-154-5p and urinary albumin excretion rates in patients with type 2 diabetes

Huiwen Ren, Can Wu, Ying Shao, Shuang Liu, Yang Zhou, Qiuyue Wang

Frontiers of Medicine 2020, Volume 14, Issue 5,   Pages 642-650 doi: 10.1007/s11684-019-0719-3

Abstract: This study aimed to investigate the correlation between serum miR-154-5p and urinary albumin to creatinineCirculating miR-154-5p, inflammatory (C-reactive protein (CRP); erythrocyte sedimentation rate (ESR);UACR, miR-154-5p, glycated hemoglobin (HbA1c), serum creatinine (sCr), blood urea nitrogen (BUN), ESRElevated levels of UACR and miR-154-5p were directly correlated with HbA1c, sCr, BUN, ESR, CRP, VEGF,TNF-α, TGF-β1, and FN and negatively correlated with eGFR ( <0.05). miR-154-5p, HbA1c, sCr, BUN, eGFR

Keywords： type 2 diabetes mellitus     diabetic kidney disease     miR-154-5p     urinary albumin to creatinine ratio    

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Long noncoding RNA LOC646029 functions as a ceRNA to suppress ovarian cancer progression through the miR

Frontiers of Medicine   Pages 924-938 doi: 10.1007/s11684-023-1004-z

Abstract: Mechanistically, LOC646029 served as a miR-627-3p sponge to promote the expression of Sprouty-related

Keywords： ovarian cancer     lncRNA LOC646029     metastasis     microRNA 627-3p     SPRED1    

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lncR-GAS5 upregulates the splicing factor to impair endothelial autophagy, leading to atherogenesis

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 317-329 doi: 10.1007/s11684-022-0931-4

Abstract: Further results revealed that overexpression of the lncR-GAS5-targeted gene miR-193-5p promoted autophagyNotably, miR-193-5p overexpression decreased plaque size and increased collagen content.In conclusion, lncR-GAS5 overexpression arrested endothelial autophagy through the miR-193-5p/SRSF10Thus, miR-193-5p/SRSF10 may serve as a novel treatment target for atherosclerosis.

Keywords： lncR-GAS5     miR-193-5p     splicing factor SRSF10     autophagy     atherogenesis    

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Valveless pumping using a two-stage impedance pump

C.-C. LEE, Y. A. ABAKR, K.-C. WOO

Frontiers of Mechanical Engineering 2013, Volume 8, Issue 3,   Pages 311-318 doi: 10.1007/s11465-013-0270-x

Abstract:

Impedance pump is defined as a type of valveless pumping mechanism, where an elastic tube is joined with a tube of different impedance, a periodic asymmetrical compression on part of the elastic tube will produce a unidirectional flow. Numerical and experimental studies had been conducted in the past, but little experimental work was found to exploit the principle of multi-stage impedance pumping for fluid transportation. This paper concentrates on the fluid behavior for an open-loop two-stage system experimentally. The aim of this work is to have an insight on the deliverable head and pumping rate of an open-loop two-stage impedance pumping system. This paper generally investigates the effect of different parameters towards the generation of unidirectional flows and composite flow of two opposite directions. Results obtained are of significant values.

Keywords： valveless pumping     open-loop     two-stage     unidirectional     composite    

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Design of GPRS Data Terminal Based on S3C2410

Sun Xueyong

Strategic Study of CAE 2007, Volume 9, Issue 12,   Pages 94-96

Abstract: hardware structure and working process of the embedded Internetconnected platform, which regards S3C2410

Keywords： GPRS；embedded Internet；S3C2410；SIM100-E    

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Bioinspired C/TiO

Jian LI, Likun GAO, Wentao GAN

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 4,   Pages 459-464 doi: 10.15302/J-FASE-2017178

Abstract: Hierarchical structures of -carbon-TiO (PP-C-TiO ) were confirmed by SEM observations.Furthermore, the conduction and valence bands of the PP-C-TiO are more negative than the correspondingThat is, the presence of C originating from wings in the PP-C-TiO could extend the photoresponsiveness

Keywords： bioinspired     butterfly wings     C/TiO2     photocatalyst     visible light    

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MicroRNA-148b promotes proliferation of hair follicle cells by targeting

Wanbao YANG,Qinqun LI,Bo SU,Mei YU

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 1,   Pages 72-80 doi: 10.15302/J-FASE-2016089

Abstract: In our study, we found by qRT-PCR that miR-148b was significantly upregulated in sheep wool follicleOverexpression of miR-148b promoted proliferation of both HHDPC and HHGMC.By using the TOPFlash system we demonstrated that miR-148b could activate Wnt/β-catenin pathway andSubsequently was further identified as the target of miR-148b using western blotting.These results were considered to indicate that miR-148b could activate the Wnt/β-catenin signal pathway

Keywords： miR-148b     hair follicle     proliferation     NFAT5     Wnt10b    

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Antithrombin deficiency and decreased protein C activity in a young man with venous thromboembolism:

Dong Wang, Min Tian, Guanglin Cui, Dao Wen Wang

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 319-323 doi: 10.1007/s11684-017-0553-4

Abstract:

Antithrombin and protein C are two crucial members in the anticoagulant system and play importantrevealed that the patient presented type I antithrombin deficiency combined with decreased protein Cactivity resulting from a small insertion mutation c.848_849insGATGT in and a short deletion variantc.572_574delAGA in .This study demonstrates that the combination of antithrombin deficiency and decreased protein C activity

Keywords： antithrombin deficiency     protein C activity     mutation     variant     venous thromboembolism     anticoagulants    

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Atomistic simulations of plasma catalytic processes

Erik C. Neyts

Frontiers of Chemical Science and Engineering 2018, Volume 12, Issue 1,   Pages 145-154 doi: 10.1007/s11705-017-1674-7

Abstract: There is currently a growing interest in the realisation and optimization of hybrid plasma/catalyst systems for a multitude of applications, ranging from nanotechnology to environmental chemistry. In spite of this interest, there is, however, a lack in fundamental understanding of the underlying processes in such systems. While a lot of experimental research is already being carried out to gain this understanding, only recently the first simulations have appeared in the literature. In this contribution, an overview is presented on atomic scale simulations of plasma catalytic processes as carried out in our group. In particular, this contribution focusses on plasma-assisted catalyzed carbon nanostructure growth, and plasma catalysis for greenhouse gas conversion. Attention is paid to what can routinely be done, and where challenges persist.

Keywords： atomic scale simulation     plasma-catalyst    

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Title Author Date Type Operation

Effects of miR-200c on the migration and invasion abilities of human prostate cancer Du145 cells and

Runlin Shi,Haibing Xiao,Tao Yang,Lei Chang,Yuanfeng Tian,Bolin Wu,Hua Xu

Journal Article

The microRNA, miR-29c, participates in muscle development through targeting the

Weiya ZHANG,Wei WEI,Yuanyuan ZHAO,Shuhong ZHAO,Xinyun LI

Journal Article

200 km Per Hour一The Best Choice for Beijing - Shanghai Express Railway

Li Yushan

Journal Article

The expression mode of hsa-miR-197 in uterine leiomyomas tissue and related bioinformatics analysis

Xu Qing,Fu Ziyi,Wu Xiaoli,Huangfu Yushuang and Ling Jing

Journal Article

Overexpressed miR-9 promotes tumor metastasis via targeting E-cadherin in serous ovarian cancer

Bo Zhou, Hongbin Xu, Meng Xia, Chaoyang Sun, Na Li, Ensong Guo, Lili Guo, Wanying Shan, Hao Lu, Yifan Wu, Yuan Li, Degui Yang, Danhui Weng, Li Meng, Junbo Hu, Ding Ma, Gang Chen, Kezhen Li

Journal Article

-Derived miR162a Functions on Osteoporosis Through Directly Promoting Osteoblast Formation

Chunyan Gu,Xichao Yu,Xiaozhu Tang,Leilei Gong,Jingquan Tan,Yuanjiao Zhang,Huili Zheng,Ze Wang,Chenqian Zhang,Yejin Zhu,Zuojian Zhou,Heming Yu,Kai Xu,Jinao Duan,Xiaosong Gu,Ye Yang,

Journal Article

Correlation between serum miR-154-5p and urinary albumin excretion rates in patients with type 2 diabetes

Huiwen Ren, Can Wu, Ying Shao, Shuang Liu, Yang Zhou, Qiuyue Wang

Journal Article

Long noncoding RNA LOC646029 functions as a ceRNA to suppress ovarian cancer progression through the miR

Journal Article

lncR-GAS5 upregulates the splicing factor to impair endothelial autophagy, leading to atherogenesis

Journal Article

Valveless pumping using a two-stage impedance pump

C.-C. LEE, Y. A. ABAKR, K.-C. WOO

Journal Article

Design of GPRS Data Terminal Based on S3C2410

Sun Xueyong

Journal Article

Bioinspired C/TiO

Jian LI, Likun GAO, Wentao GAN

Journal Article

MicroRNA-148b promotes proliferation of hair follicle cells by targeting

Wanbao YANG,Qinqun LI,Bo SU,Mei YU

Journal Article

Antithrombin deficiency and decreased protein C activity in a young man with venous thromboembolism:

Dong Wang, Min Tian, Guanglin Cui, Dao Wen Wang

Journal Article

Atomistic simulations of plasma catalytic processes

Erik C. Neyts

Journal Article