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Inhibition of the nuclear export of p65 and IQCG in leukemogenesis by NUP98-IQCG

Mengmeng Pan,Qiyao Zhang,Ping Liu,Jinyan Huang,Yueying Wang,Saijuan Chen

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 410-419 doi: 10.1007/s11684-016-0489-0

Abstract: CRM1-mediated nuclear export of p65 and enhances the transcriptional activity of nuclear factor-κB.

Keywords: NUP98-IQCG     nuclear export     NF-κB     CRM1    

Inhibition of NF-kappa B can enhance Fas-mediated apoptosis in leukemia cell line HL-60

Li WANG, Shi ZHAO, Hong-Xiang WANG, Ping ZOU

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 323-328 doi: 10.1007/s11684-010-0026-5

Abstract: This study explored the effects of nuclear factor-kappa B (NF-κB) inhibitor Bay 11-7082 on Fas/FasL system

Keywords: nuclear factor-kappa B     Fas/FasL system     HL-60     Bay 11-7082    

Expression of STAT6 and NFB p65 in the colon mucosa of patients with ulcerative colitis

Rui ZHU MD, Heng FAN MD, Lin SHEN MD, Jianguo LIU BD, Jia ZHAO MM,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 475-479 doi: 10.1007/s11684-009-0086-6

Abstract: The expression of signal transducer and activator of transcription 6 (STAT6) and nuclear factor-κB(NFB) in the colonic mucosa of patients with ulcerative colitis (UC) was examined.polymerase chain reaction and immunohistochemistry were used to detect the expression of STAT6 and NFThe results showed that the expression levels of STAT6 and NFκB p65 in the colonic mucosa of patientsThese data suggest that STAT6 and NFκB p65 perhaps play an important role in the pathogenesis of

Keywords: ulcerative colitis     signal transducer and activator of transcription 6 (STAT6)     nuclear factor-κ     Bp65 (NF    B p65)    

Effect of compound Sophorae Flavescentis Jiechangrong capsule on expression of NFB p65 and STAT6

Heng FAN MD, Jia ZHAO MM, Lin SHEN BM, Qing TANG MD, Zhexin SHOU MM, Li LIANG BM, Yi LIAO BM, Xiaoyan CHEN BM,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 480-484 doi: 10.1007/s11684-009-0083-9

Abstract: compound Sophorae Flavescentis Jiechangrong capsule (CSFJC) on the expression of nuclear factor-κBp65 (NFB p65) and signal transducer and activator of transcription 6 (STAT6) in the intestinalAfter the treatment, the expression of NFB p65 and STAT6 in the two groups was decreased, andthe decrease of NFB p65 and STAT6 expression in TCM group was more significant than in WM groupIt was concluded that CSFJC can inhibit the activation and expression of NFB p65 and STAT6 in

Keywords: colitis     ulcerative     compound Sophorae Flavescentis Jiechangrong capsule     nuclear factor-κ     B p65 (NF    B p65)     signal transducer and activator of transcription 6 (STAT6)    

Role of membrane and compound properties in affecting the rejection of pharmaceuticals by different RO/NF

Yang-ying Zhao, Fan-xin Kong, Zhi Wang, Hong-wei Yang, Xiao-mao Wang, Yuefeng F. Xie, T. David Waite

Frontiers of Environmental Science & Engineering 2017, Volume 11, Issue 6, doi: 10.1007/s11783-017-0975-x

Abstract: The performance of a low-pressure reverse osmosis (LPRO) membrane (ESPA1), a tight NF membrane (NF90)and two loose NF membranes (HL and NF270) was compared for the rejection of 23 different pharmaceuticalsElectrostatic effects were more significant in PhAC rejection by loose NF membranes than tight NF andThe adverse effect of adsorption on rejection by HL and ESPA1 was more substantial than NF270 and NF90High-pressure membranes like NF90 and NF270 have a high promise in TrOC removal from contaminated water

Keywords: Trace organic compounds (TrOCs)     Nanofiltration (NF)     Adsorption     Membrane properties     Water treatment    

Application study on the municipal landfill leachate treatment by MBR-NF process

Lu Jilai,Huang Juan,Wang Huizhong,Zhang Limin,Xia Mingfang,Li Yuezhong,Ren Hongqiang

Strategic Study of CAE 2008, Volume 10, Issue 10,   Pages 61-63

Abstract: The MBR-NF process was adopted to treat the leachate.Compared with the other leachate treatment processes, the MBR-NF has significant advantages on both technique

Keywords: landfill leachate     MBR     NF    

Role of water chemistry on estrone removal by nanofiltration with the presence of hydrophobic acids

Xue JIN,Jiangyong HU

Frontiers of Environmental Science & Engineering 2015, Volume 9, Issue 1,   Pages 164-170 doi: 10.1007/s11783-014-0747-9

Abstract: known to improve the rejection of steroid hormone estrone by reverse osmosis (RO) and nanofiltration (NFstudy, the effects of solution chemistry (solution pH and ionic strength) on the estrone rejection by NFThese results can be important for NF application in direct/indirect potable water reuse.

Keywords: indirect potable water reuse     steroid hormone     nanofiltration(NF)     rejection     water chemistry     hydrophobic    

Current hepatitis B treatment guidelines and future research directions

Jonathan Skupsky,Ke-Qin Hu

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 145-157 doi: 10.1007/s11684-014-0335-1

Abstract:

Hepatitis B virus (HBV) infection causes a tremendous clinical burden across the world with more than

Keywords: chronic hepatitis B     HBV treatment guidelines     APASL guidelines     EASL guidelines     AASLD guidelines    

Clinical characteristics and risk factors of COVID-19 patients with chronic hepatitis B: a multi-center

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 111-125 doi: 10.1007/s11684-021-0854-5

Abstract: 19 patients, the association of liver injury caused by specific subtype especially chronic hepatitis B

Keywords: COVID-19     chronic hepatitis B     liver injury     coagulation dysfunction    

CPAL, as a New Mediator of Cardiomyocyte Metabolic Alterations and Pyroptosis, Regulates Myocardial Infarction Injury in Mice Article

Jiamin Li, Hongru Xue, Ning Xu, Liling Gong, Ming Li, Sijia Li, Di Huang, Qingwei Zhang, Pengyu Li, Qingsui Li, Hang Yu, Yining Liu, Yadong Xue, Haixin Chen, Jiali Liu, Wanyu Zhang, Mingbin Liu, Siyu Chang, Xianzhi Lang, Xingmiao Zhao, Weijie Du, Benzhi Cai, Ning Wang, Baofeng Yang

Engineering 2023, Volume 20, Issue 1,   Pages 49-62 doi: 10.1016/j.eng.2022.08.012

Abstract: Mechanistically, CPAL is shown to bind directly to nuclear factor kappa B (NFκB) and to act asan activator of NFκB to induce NFκB phosphorylation in cardiomyocytes.expression at the transcriptional level and consequently promotes the release of interleukin (IL)-18 and IL-1b

Keywords: Myocardial infarction     Pyroptosis     CPAL     NFκB     Inflammation    

Vaccine therapies for chronic hepatitis B: can we go further?

Yumei Wen, Xuanyi Wang, Bin Wang, Zhenhong Yuan

Frontiers of Medicine 2014, Volume 8, Issue 1,   Pages 17-23 doi: 10.1007/s11684-014-0313-7

Abstract:

Chronic hepatitis B is a major health burden worldwide.treatment, therapeutic vaccination is a promising new strategy for the control of chronic hepatitis B.basis of the major specific and non-specific immune dysregulations and defects in chronic hepatitis B

Keywords: chronic hepatitis B     therapeutic     antigen-antibody complexes     DNA     vaccine    

Chronic hepatitis B virus infection: epidemiology, prevention, and treatment in China

Rui Yu,Rong Fan,Jinlin Hou

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 135-144 doi: 10.1007/s11684-014-0331-5

Abstract:

Chronic hepatitis B is a major health problem in China.The universal vaccination program since 1992 has changed the epidemiology of hepatitis B virus infectionThe most prevalent hepatitis B virus strains in China are genotypes B and C, whereas those in westernChronic hepatitis B poses a heavy burden to the society in China.

Keywords: chronic hepatitis B     epidemiology     prevention     treatment    

Durability analysis of B grade steel side-frame based on the PFM method

Li Wei and Wang Ping

Strategic Study of CAE 2011, Volume 13, Issue 1,   Pages 56-61

Abstract: simulated durability test is performed to study the details with angle of side-frame of wagon bogie made of B

Keywords: durability     fatigue     B grade steel     crack    

Impact analysis of compressor rotor blades of an aircraft engine

Y B SUDHIR SASTRY, B G KIROS, F HAILU, P R BUDARAPU

Frontiers of Structural and Civil Engineering 2019, Volume 13, Issue 3,   Pages 505-514 doi: 10.1007/s11709-018-0493-3

Abstract: Frequent failures due to foreign particle impacts are observed in compressor blades of the interceptor fighter MIG-23 aircraft engines in the Ethiopian air force, supplied by the Dejen Aviation Industry. In this paper, we made an attempt to identify the causes of failure and hence recommend the suitable materials to withstand the foreign particle impacts. Modal and stress analysis of one of the recently failed MIG-23 gas turbine compressor blades made up of the following Aluminum based alloys: 6061-T6, 7075-T6, and 2024-T4, has been performed, apart from the impact analysis of the rotor blades hit by a granite stone. The numerical results are correlated to the practical observations. Based on the modal, stress and impact analysis and the material properties of the three considered alloys, alloy 7075-T6 has been recommended as the blade material.

Keywords: axial flow compressor     rotor and stator blades     aircraft engine     stress and impact analysis     aluminum alloys    

Comprehensive treatment of acute-on-chronic liver failure in a patient with hepatitis B: a case report

Lei Li,Yimei Liu,Tiancheng Luo,Jian Zhou,Yingyong Hou,Xizhong Shen,Jiyao Wang

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 250-253 doi: 10.1007/s11684-014-0333-3

Abstract: The patient has suffered from hepatitis B for 30 years.Comprehensive treatments included effective inhibition of hepatitis B virus replication and intensive

Keywords: acute-on-chronic liver failure     submassive necrosis     viral hepatitis B     esophageal variceal bleeding     liver    

Title Author Date Type Operation

Inhibition of the nuclear export of p65 and IQCG in leukemogenesis by NUP98-IQCG

Mengmeng Pan,Qiyao Zhang,Ping Liu,Jinyan Huang,Yueying Wang,Saijuan Chen

Journal Article

Inhibition of NF-kappa B can enhance Fas-mediated apoptosis in leukemia cell line HL-60

Li WANG, Shi ZHAO, Hong-Xiang WANG, Ping ZOU

Journal Article

Expression of STAT6 and NFB p65 in the colon mucosa of patients with ulcerative colitis

Rui ZHU MD, Heng FAN MD, Lin SHEN MD, Jianguo LIU BD, Jia ZHAO MM,

Journal Article

Effect of compound Sophorae Flavescentis Jiechangrong capsule on expression of NFB p65 and STAT6

Heng FAN MD, Jia ZHAO MM, Lin SHEN BM, Qing TANG MD, Zhexin SHOU MM, Li LIANG BM, Yi LIAO BM, Xiaoyan CHEN BM,

Journal Article

Role of membrane and compound properties in affecting the rejection of pharmaceuticals by different RO/NF

Yang-ying Zhao, Fan-xin Kong, Zhi Wang, Hong-wei Yang, Xiao-mao Wang, Yuefeng F. Xie, T. David Waite

Journal Article

Application study on the municipal landfill leachate treatment by MBR-NF process

Lu Jilai,Huang Juan,Wang Huizhong,Zhang Limin,Xia Mingfang,Li Yuezhong,Ren Hongqiang

Journal Article

Role of water chemistry on estrone removal by nanofiltration with the presence of hydrophobic acids

Xue JIN,Jiangyong HU

Journal Article

Current hepatitis B treatment guidelines and future research directions

Jonathan Skupsky,Ke-Qin Hu

Journal Article

Clinical characteristics and risk factors of COVID-19 patients with chronic hepatitis B: a multi-center

Journal Article

CPAL, as a New Mediator of Cardiomyocyte Metabolic Alterations and Pyroptosis, Regulates Myocardial Infarction Injury in Mice

Jiamin Li, Hongru Xue, Ning Xu, Liling Gong, Ming Li, Sijia Li, Di Huang, Qingwei Zhang, Pengyu Li, Qingsui Li, Hang Yu, Yining Liu, Yadong Xue, Haixin Chen, Jiali Liu, Wanyu Zhang, Mingbin Liu, Siyu Chang, Xianzhi Lang, Xingmiao Zhao, Weijie Du, Benzhi Cai, Ning Wang, Baofeng Yang

Journal Article

Vaccine therapies for chronic hepatitis B: can we go further?

Yumei Wen, Xuanyi Wang, Bin Wang, Zhenhong Yuan

Journal Article

Chronic hepatitis B virus infection: epidemiology, prevention, and treatment in China

Rui Yu,Rong Fan,Jinlin Hou

Journal Article

Durability analysis of B grade steel side-frame based on the PFM method

Li Wei and Wang Ping

Journal Article

Impact analysis of compressor rotor blades of an aircraft engine

Y B SUDHIR SASTRY, B G KIROS, F HAILU, P R BUDARAPU

Journal Article

Comprehensive treatment of acute-on-chronic liver failure in a patient with hepatitis B: a case report

Lei Li,Yimei Liu,Tiancheng Luo,Jian Zhou,Yingyong Hou,Xizhong Shen,Jiyao Wang

Journal Article