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《医学前沿(英文)》 2022年 第16卷 第5期 页码 760-765 doi: 10.1007/s11684-021-0899-5
关键词: lung transplantation donation after brain death waitlist
The influence of brain death on donor liver and the potential mechanisms of protective intervention
null
《医学前沿(英文)》 2011年 第5卷 第1期 页码 8-14 doi: 10.1007/s11684-011-0109-y
Brain-dead donors have become one of the main sources of organs for transplantation in Western countries. The quality of donor organs is closely related to the outcome of the transplantation. Experimental studies have confirmed the inferior graft survival of livers from brain-dead donors compared with those from living donors. Studies conducted in the past 10 years have shown that brain death is associated with effects on the decreased donor organ quality. However, whether the decrease in the viability of donor organs is caused by brain death or by the events before and after brain death remains uncertain. The purpose of this review is to introduce the advances and controversies regarding the influence of brain death on the viability of donor livers and to summarize the mechanisms of the different protective interventions for donor livers.
关键词: brain death donor liver
Orlistat induces ferroptosis-like cell death of lung cancer cells
《医学前沿(英文)》 2021年 第15卷 第6期 页码 922-932 doi: 10.1007/s11684-020-0804-7
Experimental study on the establishment and maintenance of brain death model with pigs
ZHANG Shuijun, SHI Jihua, ZHAI Wenlong, SONG Yan, CHEN Shi
《医学前沿(英文)》 2007年 第1卷 第2期 页码 161-166 doi: 10.1007/s11684-007-0030-6
Sudden death due to arrhythmogenic right ventricular cardiomyopathy: Two case reports
CHEN Xinshan, ZHANG Yigu, RAO Guangxun, HUANG Guangzhao
《医学前沿(英文)》 2007年 第1卷 第3期 页码 338-342 doi: 10.1007/s11684-007-0065-8
关键词: sarcoplasmic coagulation acquired ventricular myocardium sino-atrial autopsied
Protein aggregation in association with delayed neuronal death in rat model of brain ischemia
GE Pengfei, FU Shuanglin, LI Wenchen, WANG Chonghao, ZHOU Chuibing, LUO Yinan, LUO Tianfei
《医学前沿(英文)》 2008年 第2卷 第1期 页码 70-74 doi: 10.1007/s11684-008-0013-2
Guoxia MA, Jinnan WANG, Fang YU, Xiaomin GUO, Yanshen ZHANG, Chao LI
《环境科学与工程前沿(英文)》 2016年 第10卷 第5期 doi: 10.1007/s11783-016-0849-7
关键词: Air pollution Public health Premature deaths Health assessment
null
《医学前沿(英文)》 2013年 第7卷 第3期 页码 333-344 doi: 10.1007/s11684-013-0275-1
This study reports the first death caused by a novel avian influenza A (H7N9) virus in Zhejiang Province, China. The patient had chronic hepatitis B and history of exposure to poultry. The patient initially complained of diarrhea and influenza-like symptoms on March 7 and 14 respectively. The disease progressed to severe pneumonia, sustained hypoxia, and coagulation abnormalities. The patient died on March 27 because of respiratory failure, multiple organ failure, and disseminated intravascular coagulation without oseltamivir treatment. This H7N9 virus from Zhejiang is highly similar to isolates obtained from Shanghai, Jiangsu, Anhui, etc. Analysis of hemagglutinin, neuramidinase, and matrix genes indicated that the isolates share the same avian origin, have low virulence, and are sensitive to oseltamivir, but are resistant to adamantine. Only the isolate that caused the fatality exhibited substitution of Q226I in the HA gene, which indicates a potentially enhanced human affinity. The secondary transmission rate was 1.6% (2/125). Only two health workers presented with influenza-like symptoms, and they subsequently tested negative for H7N9 RNA. In conclusion, underlying disease, late diagnosis, and untimely antiviral treatment are possible high-risk factors for infections and death caused by the low-pathogenicity avian influenza A (H7N9). Person-to-person transmission of the H7N9 virus was not detected among close contacts, but such transmission should be investigated in the future. Expanding and enhancing surveillance will help in the early discovery and diagnosis of suspected cases, which will reduce the number of severe cases and deaths.
关键词: avian influenza A (H7N9) virus epidemiology contacts person-to-person transmission
Immunological effects of nano-enabled hyperthermia for solid tumors: opportunity and challenge
《化学科学与工程前沿(英文)》 2022年 第16卷 第3期 页码 333-344 doi: 10.1007/s11705-021-2059-5
关键词: nano-enabled hyperthermia immunogenic cell death heterogeneous immunological landscape tumor microenvironment
Using mRNA to investigate the effect of low-pressure ultraviolet disinfection on the viability of
Chao Yang, Wenjun Sun, Xiuwei Ao
《环境科学与工程前沿(英文)》 2019年 第13卷 第2期 doi: 10.1007/s11783-019-1111-x
UV can induce damages on mRNA consistently among different genes. SOS response was more active after UV treatment. Programmed cell death was not found to be more active after UV treatment.
关键词: UV disinfection Viability mRNA SOS response Programmed cell death
Zheng AO, Chengfa ZHAO, Yanmin GAN, Xiao WU, Junsong SHI, Enqin ZHENG, Dewu LIU, Gengyuan CAI, Zhenfang WU, Zicong LI
《农业科学与工程前沿(英文)》 2019年 第6卷 第1期 页码 54-60 doi: 10.15302/J-FASE-2018249
Somatic cell nuclear transfer (SCNT)-derived piglets have significantly higher stillbirth rate and postnatal mortality rate than artificial insemination (AI)-generated piglets. The question whether the low survival rate of SCNT piglets was related to birth weight, umbilical cord or placenta development was investigated. In this study, stillbirth rate, neonatal death rate, birth weight, umbilical cord status, placental parameters and placental gene expression patterns were compared between SCNT and AI piglets. Results showed that mortality rates at birth and during the neonatal stage of SCNT piglets were significantly higher than those of AI piglets. The incidence of abnormal umbilical cord in SCNT and SCNT-liveborn (SCNT-LB) piglets was significantly higher than in AI and AI-liveborn (AI-LB) piglets. Birth weight, placental weight, placental surface area and placental efficiency in SCNT and SCNT-LB piglets were significantly lower than those of AI and AI-LB piglets. Placental expression profiles of imprinting, angiopoiesis and nutrient transport-related genes were defective in SCNT-LB piglets compared with those in AI-LB piglets. Thus, the low survival rate of SCNT piglets may be associated with abnormal umbilical cord and placenta development. These characteristics may have resulted from aberrant expression of angiogenesis, nutrient transport, and imprinting-related genes in the placentas.
基于非稳定性的5G大规模MIMO信道建模 Article
Jian-qiao CHEN, Zhi ZHANG, Tian TANG, Yu-zhen HUANG
《信息与电子工程前沿(英文)》 2017年 第18卷 第12期 页码 2101-2110 doi: 10.1631/FITEE.1700028
Nikolay V. Tsygan, Alexandr P. Trashkov, Igor V. Litvinenko, Viktoriya A. Yakovleva, Alexandr V. Ryabtsev, Andrey G. Vasiliev, Leonid P. Churilov
《医学前沿(英文)》 2019年 第13卷 第4期 页码 420-426 doi: 10.1007/s11684-019-0688-6
关键词: stroke blood–brain barrier autoimmunity innate immunity inflammation cell death
假单胞菌环状脂肽Medpeptin的生物合成及其调控植物免疫的作用机制 Article
谷医林, 李俊州, 李彦, 从珅, 王静, 马毅楠, 魏海雷
《工程(英文)》 2023年 第28卷 第9期 页码 153-165 doi: 10.1016/j.eng.2023.05.016
环状脂肽(cyclic lipopeptides, CLP)是一类由细菌产生的多功能次生代谢产物,也是一类重要的植物免疫激发子。假单胞菌环状脂肽在结构和生物活性上极其复杂和多样化。但是,目前对环状脂肽的结构及其与植物互作中的功能认识仍比较有限。本研究从地中海假单胞菌中鉴定了一种由22个氨基酸组成的新型的环状脂肽medpeptin,该脂肽由一个非核糖体肽合成酶基因簇合成并受群体感应系统调节。进一步研究发现,medpeptin可以诱导植物产生免疫反应,增强植物对病原细菌的抗性,但其自身不具备抗菌活性。利用比较转录组分析和病毒诱导的基因沉默技术解析了参与medpeptin感知植物免疫信号候选关键基因。结果显示,当沉默本氏烟中细胞壁富含亮氨酸的重复延伸蛋白NbLRX3或类受体蛋白激酶NbRLK25后,medpepatin触发的细胞死亡和对病原细菌的抗性受到严重影响,而沉默BAK1或SGT1则并未影响这一表型。本研究结果揭示了一种非典型的CLP感知机制,并为植物抗病免疫研究提供了新的借鉴。
关键词: 假单胞菌 环状脂肽 细胞死亡 富含异亮氨酸的延伸蛋白 类受体激酶
标题 作者 时间 类型 操作
Outcomes of patients awaiting lung transplantation after the implementation of donation after brain death
期刊论文
The influence of brain death on donor liver and the potential mechanisms of protective intervention
null
期刊论文
Experimental study on the establishment and maintenance of brain death model with pigs
ZHANG Shuijun, SHI Jihua, ZHAI Wenlong, SONG Yan, CHEN Shi
期刊论文
Sudden death due to arrhythmogenic right ventricular cardiomyopathy: Two case reports
CHEN Xinshan, ZHANG Yigu, RAO Guangxun, HUANG Guangzhao
期刊论文
Protein aggregation in association with delayed neuronal death in rat model of brain ischemia
GE Pengfei, FU Shuanglin, LI Wenchen, WANG Chonghao, ZHOU Chuibing, LUO Yinan, LUO Tianfei
期刊论文
Assessing the premature death due to ambient particulate matter in China’s urban areas from 2004 to 2013
Guoxia MA, Jinnan WANG, Fang YU, Xiaomin GUO, Yanshen ZHANG, Chao LI
期刊论文
The first avian influenza A (H7N9) viral infection in humans in Zhejiang Province, China: a death report
null
期刊论文
Using mRNA to investigate the effect of low-pressure ultraviolet disinfection on the viability of
Chao Yang, Wenjun Sun, Xiuwei Ao
期刊论文
Comparison of birth weight and umbilical and placental characteristics of cloned and artificial insemination-derived piglets
Zheng AO, Chengfa ZHAO, Yanmin GAN, Xiao WU, Junsong SHI, Enqin ZHENG, Dewu LIU, Gengyuan CAI, Zhenfang WU, Zicong LI
期刊论文
Autoimmunity in acute ischemic stroke and the role of blood—brain barrier: the dark side or the light one?
Nikolay V. Tsygan, Alexandr P. Trashkov, Igor V. Litvinenko, Viktoriya A. Yakovleva, Alexandr V. Ryabtsev, Andrey G. Vasiliev, Leonid P. Churilov
期刊论文