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Mutagenesis and selective breeding of a high producing

Tian WANG, Shiru JIA, Zhilei TAN, Yujie DAI, Shuai SONG, Guoliang WANG

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 2,   Pages 179-183 doi: 10.1007/s11705-012-1273-6

Abstract: -Poly- -lysine ( -PL) is an -lysine linear homopolymer, which is produced by bacteria belonging to theIn most bacteria including the genus, -lysine is a precursor of -PL and is biosynthesized by theto improve -PL productivity, resistant mutants were produced using sulfaguanidine (SG) + glycine+ -lysineFinally, one -PL-producing strain, L9, was selected.The productivity of this strain during flask fermentation was 0.77 g/L, which was 15% higher than that

Keywords： -poly-L-lysine     plasma     AHV     Streptomyces diastatochromogenes    

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Preparation of D-lysine by chemical reaction and microbial asymmetric transformation

LIU Yi, JIAO Qingcai, YIN Xiaoxing

Frontiers of Chemical Science and Engineering 2008, Volume 2, Issue 1,   Pages 40-43 doi: 10.1007/s11705-008-0023-2

Abstract: The DL-lysine crystals from the racemization of L-lysine was treated as substrate with AS1.1009 intactIn the presence of 0.10 molar equivalent of salicylaldehyde, L-lysine racemization can be completed within4 h in 1.0 mol/L of NaOH at 100°C.Under the conditions of pH 8.0, temperature 37°C, cell concentration 10 g/L, tween-80 0.5 g/L, substrateconcentration 30 g/L, and the specific activity of up to 3840 U, L-lysine can be completely degraded

Keywords： substrate     temperature     specific activity     presence     decarboxylase    

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A dual-function chemical probe for detecting erasers of lysine lipoylation

Yusheng Xie, Jie Zhang, Liu Yang, Qingxin Chen, Quan Hao, Liang Zhang, Hongyan Sun

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 121-127 doi: 10.1007/s11705-021-2051-0

Abstract: Lysine lipoylation plays vital roles in cell metabolism and redox processes.Despite the important functions of lysine lipoylation, the mechanisms for the addition and removal ofVery few useful chemical tools are available to study the interactions of lysine lipoylation with itsdual-function probe KTLlip for studying enzymatic delipoylation (eraser) activity and interaction of lysine

Keywords： dual-function     fluorescent probe     labeling     photo-cross-linker     lipoylation modification     eraser     sirtuin    

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Acetylated HOXB9 at lysine 27 is of differential diagnostic value in patients with pancreatic ductal

Xiaoran Sun, Jiagui Song, Jing Zhang, Jun Zhan, Weigang Fang, Hongquan Zhang

Frontiers of Medicine 2020, Volume 14, Issue 1,   Pages 91-100 doi: 10.1007/s11684-019-0696-6

Abstract: Pancreatic ductal adenocarcinoma (PDAC) is the ninth most common human malignancy and the sixth leading cause of cancer-related death in China. AcK27-HOXB9 is a newly identified HOXB9 post-transcriptional modification that can predict the outcome in lung adenocarcinoma and colon cancer well. However, the role of AcK27-HOXB9 in PDAC is unclear. The present study aims to investigate the differential diagnostic role of patients with AcK27-HOXB9 PDAC. Tissue microarrays consisting of 162 pancreatic tumor tissue samples from patients with PDAC and paired normal subjects were used to examine HOXB9 and AcK27-HOXB9 levels and localizations by immunohistochemical analysis and Western blot assay, respectively. HOXB9 was upregulated ( <0.0001), and AcK27-HOXB9 ( =0.0023) was downregulated in patients with PDAC. HOXB9 promoted ( =0.0115), while AcK27-HOXB9 ( =0.0279) inhibited PDAC progression. AcK27-HOXB9 predicted favorable outcome in patients with PDAC ( =0.0412). AcK27-HOXB9 also suppressed PDAC cell migration in a cell migration assay. The results of this study showed that HOXB9 promoted and AcK27-HOXB9 suppressed PDAC progression. The determination of ratio between HOXB9 and AcK27-HOXB9 exhibited potential diagnostic value in patients with PDAC.

Keywords： HOXB9     AcK27-HOXB9     PDAC    

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Ultrafast-laser-treated poly(3,4-ethylenedioxythiophene): poly(styrenesulfonate) electrodes with enhanced

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 2,   Pages 206-216 doi: 10.1007/s11705-022-2203-x

Abstract: Poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) is an important organic electrode

Keywords： PEDOT:PSS     ultrafast laser     transparent electrode     ST-PSCs     patterning    

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Hydrophilic modification of poly(aryl sulfone) membrane materials toward highly-efficient environmental

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 5,   Pages 614-633 doi: 10.1007/s11705-021-2115-1

Abstract: Poly(aryl sulfone) as a typical membrane material has been widely used due to excellent mechanical, chemicalHowever, the inherent hydrophobicity of poly(aryl sulfone) based membranes bears with the fouling issueoverview on characterizations of hydrophilic membrane and diverse hydrophilic modification approaches of polyprovided to guide the future directions to develop novel technology to manipulate the hydrophilicity of poly

Keywords： poly(aryl sulfone)     membrane separations     modification     hydrophilicity     water treatment    

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Genomic and metabolomic analysis of with enhanced poly--glutamic acid production through atmospheric

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 12,   Pages 1751-1760 doi: 10.1007/s11705-022-2211-x

Abstract: Poly-γ-glutamic acid is an extracellular polymeric substance with various applications owing toHowever, the ability of natural strains to produce poly-γ-glutamic acid is low.upregulated amino acids of M32 provided substrates for glutamate and promoted the conversion between L-The maximum poly-γ-glutamic acid yield of 14.08 g·L–1 was finally reached with 30 g·L–1 glutamate.

Keywords： ARTP mutagenesis     Bacillus licheniformis     poly-γ-glutamic acid     metabolomics    

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Preparation and characterization of poly (vinylidene fluoride)/TiO

Weiying LI, Xiuli SUN, Chen WEN, Hui LU, Zhiwei WANG

Frontiers of Environmental Science & Engineering 2013, Volume 7, Issue 4,   Pages 492-502 doi: 10.1007/s11783-012-0407-x

Abstract: Poly(vinylidene fluoride) (PVDF)/titanium dioxide (TiO ) hybrid membranes were prepared using nano-TiOcontaining 10 vol.% TiO exhibited the best hydrophilicity with an average pure water flux up to 237 L·m ·h , higher than that of unmodified PVDF membranes (155 L·m ·h ).

Keywords： poly(vinylidene fluoride) (PVDF) membrane     nano-TiO2     anti-fouling performance     water treatment    

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Effect of polyethylene glycol on the crystallization, rheology and foamability of poly(lactic acid) containing

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 12,   Pages 2074-2087 doi: 10.1007/s11705-023-2342-8

Abstract: In this study, the rheological properties, crystallization and foaming behavior of poly(lactic acid)suggested that the polyamide 6 nanofibrils and polyethylene glycol had a synergistic effect on accelerating polyFurthermore, the poly(lactic acid)/polyamide 6 foams exhibited a higher cell density and expansion ratio

Keywords： poly(lactic acid)     foaming     microfibrillation     rheological property     crystallization    

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Design and analysis of dual fuel methanol-power poly-generation

Minghua WANG , Zheng LI , Weidou NI ,

Frontiers in Energy 2009, Volume 3, Issue 3,   Pages 341-347 doi: 10.1007/s11708-009-0023-z

Abstract: A dual fuel head poly-generation flowsheet was designed based on coal gas and coke oven gas.system performance, a 1.2×10−3.2×10kg methanol and 274―496MW power poly-generation

Keywords： dual fuel     methanol-power poly-generation     CO2 and CH4 reforming     splitting ratio    

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Nano-hydroxyapatite formation via co-precipitation with chitosan-g-poly(

Yang YU, Hong ZHANG, Hong SUN, Dandan XING, Fanglian YAO

Frontiers of Chemical Science and Engineering 2013, Volume 7, Issue 4,   Pages 388-400 doi: 10.1007/s11705-013-1355-0

Abstract: With the graft copolymer of chitosan and poly( -isopropylacrylamide) in coil and globule states as atemplate respectively, a novel composite from chitosan-g-poly( -isopropylacrylamide) and nano-hydroxyapatite

Keywords： chitosan     poly(N-isopropylacrylamide)     hydroxyapatite     coil     globule     bone tissue engineering    

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Molecular diffusion in ternary poly(vinyl alcohol) solutions

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 6,   Pages 1003-1016 doi: 10.1007/s11705-021-2121-3

Abstract: The diffusion kinetics of a molecular probe—rhodamine B—in ternary aqueous solutions containing poly(For ternary poly(vinyl alcohol) solutions containing cationic or anionic surfactant, surfactant–polymer

Keywords： fluorescence correlation spectroscopy     poly(vinyl alcohol)     anomalous diffusion     crowding effects     dynamic    

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Controlled drug release of 5-amino salicylic acid by poly(2-hydroxyethylmethacrylate) grafted agar

G. Usha RANI,Kartick Prasad DEY,Srijita BHARTI,Sumit MISHRA

Frontiers of Chemical Science and Engineering 2014, Volume 8, Issue 4,   Pages 465-470 doi: 10.1007/s11705-014-1452-8

Abstract: The utilization of poly (2-hydroxyethylmethacrylate) grafted agar (Ag-g-P(HEMA)) as a matrix for the

Keywords： agar     controlled drug release     5-Amino salicylic acid     poly(2-hydroxyethylmethacrylate) grafted agar    

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Solvent-resistant porous membranes using poly(ether−ether ketone): preparation and application

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 10,   Pages 1536-1559 doi: 10.1007/s11705-022-2221-8

Abstract: Poly(ether−ether ketone) (PEEK) is a linear aromatic macromolecule, which can form semi-crystalline aggregative

Keywords： PEEK     phase inversion     solvent-resistant membrane     nanofiltration     membrane contactor    

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crystal morphology and melting behavior of isothermally crystallized composites of short carbon fiber and poly

Mingtao RUN, Hongzan SONG, Yanping HAO

Frontiers of Chemical Science and Engineering 2009, Volume 3, Issue 3,   Pages 255-264 doi: 10.1007/s11705-009-0008-9

Abstract: The spherulites of the short carbon fiber(SCF)/poly (trimethylene terephthalate) (PTT) composites formed

Keywords： poly(trimethylene terephthalate)     short carbon fiber     banded spherulites     crack    

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Title Author Date Type Operation

Mutagenesis and selective breeding of a high producing

Tian WANG, Shiru JIA, Zhilei TAN, Yujie DAI, Shuai SONG, Guoliang WANG

Journal Article

Preparation of D-lysine by chemical reaction and microbial asymmetric transformation

LIU Yi, JIAO Qingcai, YIN Xiaoxing

Journal Article

A dual-function chemical probe for detecting erasers of lysine lipoylation

Yusheng Xie, Jie Zhang, Liu Yang, Qingxin Chen, Quan Hao, Liang Zhang, Hongyan Sun

Journal Article

Acetylated HOXB9 at lysine 27 is of differential diagnostic value in patients with pancreatic ductal

Xiaoran Sun, Jiagui Song, Jing Zhang, Jun Zhan, Weigang Fang, Hongquan Zhang

Journal Article

Ultrafast-laser-treated poly(3,4-ethylenedioxythiophene): poly(styrenesulfonate) electrodes with enhanced

Journal Article

Hydrophilic modification of poly(aryl sulfone) membrane materials toward highly-efficient environmental

Journal Article

Genomic and metabolomic analysis of with enhanced poly--glutamic acid production through atmospheric

Journal Article

Preparation and characterization of poly (vinylidene fluoride)/TiO

Weiying LI, Xiuli SUN, Chen WEN, Hui LU, Zhiwei WANG

Journal Article

Effect of polyethylene glycol on the crystallization, rheology and foamability of poly(lactic acid) containing

Journal Article

Design and analysis of dual fuel methanol-power poly-generation

Minghua WANG , Zheng LI , Weidou NI ,

Journal Article

Nano-hydroxyapatite formation via co-precipitation with chitosan-g-poly(

Yang YU, Hong ZHANG, Hong SUN, Dandan XING, Fanglian YAO

Journal Article

Molecular diffusion in ternary poly(vinyl alcohol) solutions

Journal Article

Controlled drug release of 5-amino salicylic acid by poly(2-hydroxyethylmethacrylate) grafted agar

G. Usha RANI,Kartick Prasad DEY,Srijita BHARTI,Sumit MISHRA

Journal Article

Solvent-resistant porous membranes using poly(ether−ether ketone): preparation and application

Journal Article

crystal morphology and melting behavior of isothermally crystallized composites of short carbon fiber and poly

Mingtao RUN, Hongzan SONG, Yanping HAO

Journal Article