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Effects of resistin on insulin signaling in endothelial cells

Zhizhen LI, Fangping LI, Jianhong YE, Li YAN, Zuzhi FU

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 136-140 doi: 10.1007/s11684-009-0029-2

Abstract: this study was to investigate the effects of resistin on insulin signaling in human umbilical vein endothelialAkt and endothelial nitric oxide synthase (eNOS) phosphorylation levels of endothelial cells under basalshowed that resistin could significantly inhibit Akt and eNOS phosphorylation and NO production in endothelialexerted an inhibitory effect on NO production by inhibiting insulin signaling and eNOS phosphorylation in endothelial

Keywords： resistin     endothelium     nitric oxide     endothelial nitric oxide synthase     Akt-binding protein     mouse    

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Mechanism of vascular endothelial growth factor on the prevention of restenosis after angioplasty

Qigong LIU, Honglian ZHOU, Yan ZENG, Shan YE, Jiani LIU, Zaiying LU

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 177-180 doi: 10.1007/s11684-009-0021-x

Abstract: To evaluate the mechanism of vascular endothelial growth factor (VEGF) on the prevention of restenosisThen, the VSMC and human umbilical vein endothelial cells (HUVEC) were divided into control group, H

Keywords： vascular endothelial growth factors     restenosis     reactive oxygen species     endothelial cells     vascular smooth    

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Role of nitric oxide in biological effects of vascular endothelial growth factor

Qigong LIU M D , Yan ZENG , Jiani LIU , Shan YE , Yongdong LI , Zaiying LU M D ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 284-286 doi: 10.1007/s11684-009-0062-1

Abstract: To evaluate the role of nitric oxide in the biological effects of vascular endothelial growth factor(VEGF) and the possible mechanism of VEGF, the cultured vascular endothelial cells of rabbit aorta wereThe absorbance () value of vascular endothelial cells and the levels of prostaglandin (PGI), endothelinpromote the proliferation and secretion of PGI and inhibit the secretion of ET-1 and vWF in vascular endothelialimportant mediator in the process of stimulating proliferation and regulating secretion of vascular endothelial

Keywords： vascular endothelial growth factor     nitric oxide     N-nitro-L-arginine methyl ester     vascular endothelial    

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Effect of hyperlipidemia on endothelial VCAM-1 expression and the protective role of fenofibrate

WU Jun, LIN Jinchao, HE Zhaochu, OU Biru, GUO Haisen

Frontiers of Medicine 2007, Volume 1, Issue 4,   Pages 356-358 doi: 10.1007/s11684-007-0068-5

Abstract: The effect of hyperlipidemia and inflammation on endothelial functions was studied.group, hyperlipidemia rats showed lower levels of NO and ncreases in leukocyte accumulation on the endothelialsurface, also stronger and more extensive endothelial expression of VCAM-1.In fenofibrate-treated group, the expression of VCAM-1 and leukocyte accumulation on the endothelial

Keywords： endothelial     16-week treatment     leukocyte accumulation     mg/kg     NO    

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Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium

Weijian Hang, Chen Chen, Xin A. Zhang, Dao Wen Wang

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 638-643 doi: 10.1007/s11684-021-0831-z

Abstract: addition to affecting the lungs, COVID-19 can be a severe systemic inflammatory disease that is related to endothelialWe are calling for closer attention to endothelial dysfunction in COVID-19 not only for fully revealing

Keywords： COVID-19     endothelial dysfunction     inflammation reaction     cytokine storm    

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Study on the action of resistin-induced human umbilical vein endothelial cell dysfunction

LI Zhizhen, LI Fangping, YAN Li, LI Feng, LI Yan, CHENG Hua, FU Zuzhi

Frontiers of Medicine 2007, Volume 1, Issue 2,   Pages 196-199 doi: 10.1007/s11684-007-0037-z

Abstract: The aim of this paper was to investigate the effects of resistin on human umbilical vein endothelial

Keywords： endothelial     resistin stimulation     Incubation     pathogenesis     dysfunction    

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lncR-GAS5 upregulates the splicing factor to impair endothelial autophagy, leading to atherogenesis

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 317-329 doi: 10.1007/s11684-022-0931-4

Abstract: decreased LC3II/LC3I protein ratio and an elevated P62 level in lncR-GAS5-overexpressing human aortic endothelialdemonstrate that lncR-GAS5 partially contributes to atherogenesis and plaque instability by impairing endothelialIn conclusion, lncR-GAS5 overexpression arrested endothelial autophagy through the miR-193-5p/SRSF10

Keywords： lncR-GAS5     miR-193-5p     splicing factor SRSF10     autophagy     atherogenesis    

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Relationship of endothelial nitric oxide synthase gene polymorphism with blood pressure, lipid profile

TANG Zhongzhi, LI Junyao, YANG Jianhong

Frontiers of Medicine 2008, Volume 2, Issue 2,   Pages 178-181 doi: 10.1007/s11684-008-0033-y

Abstract: To study the relationship of the polymorphism of endothelial nitric oxide synthase (eNOS) gene and blood
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CD176 single-chain variable antibody fragment inhibits the adhesion of cancer cells to endothelial cells

Jiangnan Liu,Bin Yi,Zhe Zhang,Yi Cao

Frontiers of Medicine 2016, Volume 10, Issue 2,   Pages 204-211 doi: 10.1007/s11684-016-0443-1

Abstract: involved in blood spread and liver metastasis of cancer cells by mediating the adhesion of cancer cells to endothelialFurthermore, the CD176 scFv inhibits the adhesion of CD176+ cancer cells to endothelial

Keywords： CD176     Thomsen-Friedenreich antigen     scFv     cancer     therapy     adhesion     metastasis    

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Non-genetic mechanisms of diabetic nephropathy

Qiuxia Han, Hanyu Zhu, Xiangmei Chen, Zhangsuo Liu

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 319-332 doi: 10.1007/s11684-017-0569-9

Abstract: epithelial–mesenchymal transition, apoptosis and mitochondrial damage, epigenetics, and podocyte–endothelial

Keywords： inflammatory response     epithelial–mesenchymal transition     apoptosis     mitochondrial damage     epigenetics     podocyte–endothelial    

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Surface modification of biomaterials by photochemical immobilization and photograft polymerization to improve hemocompatibility

Yakai FENG, Haiyang ZHAO, Li ZHANG, Jintang GUO,

Frontiers of Chemical Science and Engineering 2010, Volume 4, Issue 3,   Pages 372-381 doi: 10.1007/s11705-010-0005-z

Abstract: The RGD sequence can enhance adhesion and growth of endothelial cells (ECs) on material surfaces and

Keywords： biomimetic amphiphilic     amphiphilic phosphorylcholine     endothelial     functional     biomaterial    

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Pluripotent stem cells exhibiting similar characteristics can be isolated from human fetal bone marrow, heart, liver, muscle, lung, derma, kidney, and fat

FANG Baijun, SONG Yongping, LIN Quande, ZHAO Chunhua, SHI Mingxia

Frontiers of Medicine 2007, Volume 1, Issue 2,   Pages 185-191 doi: 10.1007/s11684-007-0035-1

Abstract: could also differentiate into the epithelium of liver, lung, gut, as well as the hematopoietic and endothelial

Keywords： endothelial     phenomenon     ectodermal     Flk1CD34 postembryonic     irradiated non-obese    

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Changes in Lipoprotein Lipase in the Heart Following Diabetes Onset Review

Chae Syng Lee, Yajie Zhai, Brian Rodrigues

Engineering 2023, Volume 20, Issue 1,   Pages 19-25 doi: 10.1016/j.eng.2022.06.013

Abstract: To then move LPL to the endothelial cell (EC) lumen, glycosylphosphatidylinositol-anchored high-densityThis coincides with the loss of a cardioprotective growth factor—namely, vascular endothelial growth

Keywords： Cardiac metabolism     Lipoprotein lipase     Heparanase     Vascular endothelial growth factor     Diabetic cardiomyopathy    

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Construction of eukaryotic expression vector of human arresten gene and its secreted expression in HEK 293 cells

Wei LI PhD , Siming GUAN MM , Zifang SONG PhD , Qichang ZHENG PhD , Jun XIONG PhD , Dan SHANG PhD , Xiaogang SHU PhD ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 297-302 doi: 10.1007/s11684-009-0058-x

Abstract: di-phenytetrazoliumromide (MTT) assay was carried out to assess their effect on the proliferation of human umbilical vein endothelialthat the recombinant protein could significantly suppress the proliferation of human umbilical vein endothelial

Keywords： angiogenesis inhibitor     arresten     eukaryotic expression     HEK 293 cells     endothelial cells    

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Lymphatic metastasis is related to the epithelial-mesenchymal transition and expressions of VEGF, MMP-9, and COX-2 in breast cancer

Lihui WANG, Lianhong LI, Shen LV, Shujun FAN, Li ZHAN, Bo WANG, Zhong ZHANG

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 164-170 doi: 10.1007/s11684-009-0038-1

Abstract: The expressions of E-cadherin (E-Cad), N-cadherin (N-Cad), vascular endothelial cell growth factor (VEGF

Keywords： epithelial-mesenchymal transition     vascular endothelial cell growth factor     matrix metalloproteinase-9    

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Title Author Date Type Operation

Effects of resistin on insulin signaling in endothelial cells

Zhizhen LI, Fangping LI, Jianhong YE, Li YAN, Zuzhi FU

Journal Article

Mechanism of vascular endothelial growth factor on the prevention of restenosis after angioplasty

Qigong LIU, Honglian ZHOU, Yan ZENG, Shan YE, Jiani LIU, Zaiying LU

Journal Article

Role of nitric oxide in biological effects of vascular endothelial growth factor

Qigong LIU M D , Yan ZENG , Jiani LIU , Shan YE , Yongdong LI , Zaiying LU M D ,

Journal Article

Effect of hyperlipidemia on endothelial VCAM-1 expression and the protective role of fenofibrate

WU Jun, LIN Jinchao, HE Zhaochu, OU Biru, GUO Haisen

Journal Article

Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium

Weijian Hang, Chen Chen, Xin A. Zhang, Dao Wen Wang

Journal Article

Study on the action of resistin-induced human umbilical vein endothelial cell dysfunction

LI Zhizhen, LI Fangping, YAN Li, LI Feng, LI Yan, CHENG Hua, FU Zuzhi

Journal Article

lncR-GAS5 upregulates the splicing factor to impair endothelial autophagy, leading to atherogenesis

Journal Article

Relationship of endothelial nitric oxide synthase gene polymorphism with blood pressure, lipid profile

TANG Zhongzhi, LI Junyao, YANG Jianhong

Journal Article

CD176 single-chain variable antibody fragment inhibits the adhesion of cancer cells to endothelial cells

Jiangnan Liu,Bin Yi,Zhe Zhang,Yi Cao

Journal Article

Non-genetic mechanisms of diabetic nephropathy

Qiuxia Han, Hanyu Zhu, Xiangmei Chen, Zhangsuo Liu

Journal Article

Surface modification of biomaterials by photochemical immobilization and photograft polymerization to improve hemocompatibility

Yakai FENG, Haiyang ZHAO, Li ZHANG, Jintang GUO,

Journal Article

Pluripotent stem cells exhibiting similar characteristics can be isolated from human fetal bone marrow, heart, liver, muscle, lung, derma, kidney, and fat

FANG Baijun, SONG Yongping, LIN Quande, ZHAO Chunhua, SHI Mingxia

Journal Article

Changes in Lipoprotein Lipase in the Heart Following Diabetes Onset

Chae Syng Lee, Yajie Zhai, Brian Rodrigues

Journal Article

Construction of eukaryotic expression vector of human arresten gene and its secreted expression in HEK 293 cells

Wei LI PhD , Siming GUAN MM , Zifang SONG PhD , Qichang ZHENG PhD , Jun XIONG PhD , Dan SHANG PhD , Xiaogang SHU PhD ,

Journal Article

Lymphatic metastasis is related to the epithelial-mesenchymal transition and expressions of VEGF, MMP-9, and COX-2 in breast cancer

Lihui WANG, Lianhong LI, Shen LV, Shujun FAN, Li ZHAN, Bo WANG, Zhong ZHANG

Journal Article