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MicroRNAs and hepatitis viruses

Gang LI MD , Xiaojia XIONG MM ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 265-270 doi: 10.1007/s11684-009-0055-0

Abstract: years, investigators gradually brought the concept of miRNA into studies of viral infection, including hepatitisThe hepatitis B and C viruses are common causes of liver disease worldwide.It is very difficult to cure chronic hepatitis due to drug resistance during antivirus therapy.Elucidating the mechanisms of virus-host interactions in hepatitis B and C is very important in diagnosisThis article reviews the current knowledge of viral hepatitis (B and C type) at the level of miRNA and

Keywords： microRNA     hepatitis B virus     hepatitis C virus    

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Current hepatitis B treatment guidelines and future research directions

Jonathan Skupsky,Ke-Qin Hu

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 145-157 doi: 10.1007/s11684-014-0335-1

Abstract:

Hepatitis B virus (HBV) infection causes a tremendous clinical burden across the world with more than

Keywords： chronic hepatitis B     HBV treatment guidelines     APASL guidelines     EASL guidelines     AASLD guidelines    

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Chronic hepatitis B virus infection: epidemiology, prevention, and treatment in China

Rui Yu,Rong Fan,Jinlin Hou

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 135-144 doi: 10.1007/s11684-014-0331-5

Abstract:

Chronic hepatitis B is a major health problem in China.The universal vaccination program since 1992 has changed the epidemiology of hepatitis B virus infectionThe most prevalent hepatitis B virus strains in China are genotypes B and C, whereas those in westernChronic hepatitis B poses a heavy burden to the society in China.

Keywords： chronic hepatitis B     epidemiology     prevention     treatment    

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Clinical characteristics and risk factors of COVID-19 patients with chronic hepatitis B: a multi-center

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 111-125 doi: 10.1007/s11684-021-0854-5

Abstract: in COVID-19 patients, the association of liver injury caused by specific subtype especially chronic hepatitis

Keywords： COVID-19     chronic hepatitis B     liver injury     coagulation dysfunction    

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Vaccine therapies for chronic hepatitis B: can we go further?

Yumei Wen, Xuanyi Wang, Bin Wang, Zhenhong Yuan

Frontiers of Medicine 2014, Volume 8, Issue 1,   Pages 17-23 doi: 10.1007/s11684-014-0313-7

Abstract:

Chronic hepatitis B is a major health burden worldwide.antiviral treatment, therapeutic vaccination is a promising new strategy for the control of chronic hepatitisOn the basis of the major specific and non-specific immune dysregulations and defects in chronic hepatitis

Keywords： chronic hepatitis B     therapeutic     antigen-antibody complexes     DNA     vaccine    

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Comprehensive treatment of acute-on-chronic liver failure in a patient with hepatitis B: a case report

Lei Li,Yimei Liu,Tiancheng Luo,Jian Zhou,Yingyong Hou,Xizhong Shen,Jiyao Wang

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 250-253 doi: 10.1007/s11684-014-0333-3

Abstract: The patient has suffered from hepatitis B for 30 years.Comprehensive treatments included effective inhibition of hepatitis B virus replication and intensive

Keywords： acute-on-chronic liver failure     submassive necrosis     viral hepatitis B     esophageal variceal bleeding     liver    

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Correlation between viral load and liver cirrhosis in chronic hepatitis B patients

Lili LIU MM , Jiyao WANG MD , Weimin SHE MM ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 271-276 doi: 10.1007/s11684-009-0054-1

Abstract: The aim of this paper is to investigate the relationship between hepatitis B virus (HBV) DNA levels duringthe course and the progression to cirrhosis with chronic hepatitis B.A total of 239 chronic hepatitis B patients confirmed by liver biopsy between 2001 and 2007 were followedThe results of Cox model indicated that HBV-DNA levels at endpoint, stage of fibrosis, negative hepatitisProgression to cirrhosis in chronic hepatitis B patients is correlated with HBV-DNA levels during follow-up

Keywords： hepatitis B     chronic     viral load     liver cirrhosis    

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Current advances in the elimination of hepatitis B in China by 2030

Shuye Zhang, Fusheng Wang, Zheng Zhang

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 490-501 doi: 10.1007/s11684-017-0598-4

Abstract:

With its 78 million chronic carriers, hepatitis B virus (HBV) infection is still one of the leadingefficacious in suppressing HBV replication; however, it fails to completely cure patients with chronic hepatitisWork is still needed to eliminate hepatitis B in China by 2030.

Keywords： HBV     CHB     biomarker     functional cure     coinfection    

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Advances in newly developing therapy for chronic hepatitis C virus infection

Paul J. Pockros

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 166-174 doi: 10.1007/s11684-014-0334-2

Abstract:

Chronic hepatitis C virus (HCV) infection afflicts a reported 170 million people worldwide and is

Keywords： direct-acting antiviral (DAA)     nucleotide polymerase inhibitors     protease inhibitors    

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Potential use of serum HBV RNA in antiviral therapy for chronic hepatitis B in the era of nucleos(t)ide

Fengmin Lu, Jie Wang, Xiangmei Chen, Dongping Xu, Ningshao Xia

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 502-508 doi: 10.1007/s11684-017-0590-z

Abstract:

Although the efficacy of nucleos(t)ide analogue (NA) has been confirmed for treatment of chronic hepatitisIn this review, the RNA virion-like particles of hepatitis B virus (HBV) are integrated into the lifeIn contrast to hepatitis B surface antigen (HBsAg) that can originate from either the cccDNA or the integratedimplicated as a “para-functional cure,” a status nearly close to the functional cure of chronic hepatitis

Keywords： chronic hepatitis B     serum HBV RNA     nucleos(t)ide analogs     virological response     para-functional cure    

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Human menstrual blood-derived stem cells alleviate autoimmune hepatitis via JNK/MAPK signaling pathway

Frontiers of Medicine 2023, Volume 17, Issue 3,   Pages 534-548 doi: 10.1007/s11684-022-0953-y

Abstract: Autoimmune hepatitis (AIH) is a severe globally distributed liver disease that could occur at any age

Keywords： autoimmune hepatitis (AIH)     concanavalin A (Con A)     human menstrual blood-derived stem cells (MenSCs)    

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NKT cells in liver diseases

Shasha Zhu, Huimin Zhang, Li Bai

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 249-261 doi: 10.1007/s11684-018-0622-3

Abstract: In this study, we summarize recent findings on biology of natural killer T cells and their roles in hepatitisB virus and hepatitis C virus infection, autoimmune liver diseases, alcoholic liver disease, nonalcoholic

Keywords： natural killer T cells     hepatitis B virus and hepatitis C virus infection     autoimmune liver diseases     alcoholic    

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New perspective on the natural course of chronic HBV infection

Yong-Yuan Zhang,Ke-Qin Hu,Zhongping Duan

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 129-134 doi: 10.1007/s11684-014-0339-x

Abstract:

Chronic hepatitis B virus (HBV) infection is a significant threat to public health and an enormousmutant becomes predominant in the viral population following elimination of the wild-type virus in duck hepatitis

Keywords： hepatitis B virus     chronic HBV infection     natural course     hepatitis B     seroconversion    

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Association of novel mutations and heplotypes in the preS region of hepatitis B virus with hepatocellular

Jia-Xin XIE, Jian-Hua YIN, Qi ZHANG, Rui PU, Wen-Ying LU, Hong-Wei ZHANG, Guang-Wen CAO, Jun ZHAO, Hong-Yang WANG,

Frontiers of Medicine 2010, Volume 4, Issue 4,   Pages 419-429 doi: 10.1007/s11684-010-0160-0

Abstract: The association of viral mutations and haplotypic carriages with mutations in the preS region of hepatitis

Keywords： hepatitis B virus     hepatocellular carcinoma     mutation     genotype     haplotype    

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Association of miRNA-122-binding site polymorphism at the interleukin-1 α gene and its interaction with hepatitis

Du Yan, Han Xue, Pu Rui, Xie Jiaxin, Zhang Yuwei, Cao Guangwen

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 217-226 doi: 10.1007/s11684-014-0326-2

Abstract: binding site polymorphism at the IL-1A gene and its multiplicative interactions with hepatitis

Keywords： hepatocellular carcinoma (HCC)     interaction     miRNA-122-binding site     IL-1A     rs3783553     hepatitis B virus (    

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Title Author Date Type Operation

MicroRNAs and hepatitis viruses

Gang LI MD , Xiaojia XIONG MM ,

Journal Article

Current hepatitis B treatment guidelines and future research directions

Jonathan Skupsky,Ke-Qin Hu

Journal Article

Chronic hepatitis B virus infection: epidemiology, prevention, and treatment in China

Rui Yu,Rong Fan,Jinlin Hou

Journal Article

Clinical characteristics and risk factors of COVID-19 patients with chronic hepatitis B: a multi-center

Journal Article

Vaccine therapies for chronic hepatitis B: can we go further?

Yumei Wen, Xuanyi Wang, Bin Wang, Zhenhong Yuan

Journal Article

Comprehensive treatment of acute-on-chronic liver failure in a patient with hepatitis B: a case report

Lei Li,Yimei Liu,Tiancheng Luo,Jian Zhou,Yingyong Hou,Xizhong Shen,Jiyao Wang

Journal Article

Correlation between viral load and liver cirrhosis in chronic hepatitis B patients

Lili LIU MM , Jiyao WANG MD , Weimin SHE MM ,

Journal Article

Current advances in the elimination of hepatitis B in China by 2030

Shuye Zhang, Fusheng Wang, Zheng Zhang

Journal Article

Advances in newly developing therapy for chronic hepatitis C virus infection

Paul J. Pockros

Journal Article

Potential use of serum HBV RNA in antiviral therapy for chronic hepatitis B in the era of nucleos(t)ide

Fengmin Lu, Jie Wang, Xiangmei Chen, Dongping Xu, Ningshao Xia

Journal Article

Human menstrual blood-derived stem cells alleviate autoimmune hepatitis via JNK/MAPK signaling pathway

Journal Article

NKT cells in liver diseases

Shasha Zhu, Huimin Zhang, Li Bai

Journal Article

New perspective on the natural course of chronic HBV infection

Yong-Yuan Zhang,Ke-Qin Hu,Zhongping Duan

Journal Article

Association of novel mutations and heplotypes in the preS region of hepatitis B virus with hepatocellular

Jia-Xin XIE, Jian-Hua YIN, Qi ZHANG, Rui PU, Wen-Ying LU, Hong-Wei ZHANG, Guang-Wen CAO, Jun ZHAO, Hong-Yang WANG,

Journal Article

Association of miRNA-122-binding site polymorphism at the interleukin-1 α gene and its interaction with hepatitis

Du Yan, Han Xue, Pu Rui, Xie Jiaxin, Zhang Yuwei, Cao Guangwen

Journal Article