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Numerical study of EGR effects on reducing the pressure rise rate of HCCI engine combustion

Gen CHEN, Norimasa IIDA, Zuohua HUANG,

《能源前沿（英文）》 2010年 第4卷 第3期   页码 376-385 doi: 10.1007/s11708-010-0118-6

摘要： The effects of the inert components of exhaust gas recirculation (EGR) gas on reducing the pressure rise rate of homogeneous charge compression ignition engine combustion were investigated numerically by utilizing the CHEMKIN II package and its SENKIN code, as well as Curran’s dimethyl ether reaction scheme. Calculations were conducted under constant volume combustion and engine combustion (one compression and one expansion only, respectively) conditions. Results show that with constant fuel amount and initial temperature and pressure, as EGR ratio increases, combustion timings are retarded and the duration of thermal ignition preparation extends non-linearly; peak values of pressure, pressure rising rate (PRR), and temperature decrease; and peak values of heat release rate in both low temperature heat release (LTHR) and high temperature heat release decrease. Moreover, maximum PRR decreases as CA50 is retarded. With constant fuel amount, mixtures with different EGR ratios can obtain the same CA50 by adjusting the initial temperature. Under the same CA50, as EGR ratio increases, the LTHR timing is advanced and the duration of thermal ignition preparation is extended. Maximum PRR is almost constant with the fixed CA50 despite the change in EGR ratio, indicating that the influence of EGR dilution on chemical reaction rate is offset by other factors. Further investigation on the mechanism of this phenomenon is needed.

关键词： HCCI engine     combustion     EGR     DME     CA50     PRR    

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P50 auditory sensory gating in first onset schizophrenics and normal healthy adults

WANG Hongxing, ZHANG Mingdao, CHEN Xingshi, LOU Feiying, LIANG Jianhua, CHEN Chong, SHI Tiantao, LU Qiulin

《医学前沿（英文）》 2007年 第1卷 第4期   页码 429-432 doi: 10.1007/s11684-007-0084-5

摘要： The aim of this research was to investigate the variations of P50 auditory sensory gating (P50) in normal healthy adults and the first onset schizophrenics. By using the American Nicolet Bravo electromyography/evoked potential (EMG/EP) system, P50 was measured with conditioning-testing paradigm (paired-click stimuli S1 and S2 were used) in 58 first onset schizophrenics and 108 healthy adults, and the Positive and Negative Syndrome Scale (PANSS) was applied. The following three conclusions have been reached. (1) In normal control (NC) group, measured from central, anterior and posterior zone (Cz, Fz and Pz respectively), there were no statistical differences (>0.05) between S1 and S2 evoked P50 peak latencies (S1-P50 and S2-P50); the amplitudes of S2-P50 [(2.2±1.4), (2.3±1.5) and (2.1±1.4) μV respectively] reduced significantly as compared with S1-P50 [(5.6±3.3), (5.6±3.9) and (4.9±2.8) μV respectively] (<0.01); the S2/S1 ration, S1-S2 difference, and 100 (1-S2/S1) had no statistical differences (>0.05). (2) Compared with NC, the schizophrenic group significantly showed lower S1-P50 amplitudes (<0.01, except at Pz in which = 2.030, = 0.042), higher S2-P50 amplitudes, higher S2/S1 ratio, lower S1-S2 difference, and more decreased 100 (1-S2/S1) (<0.01) at Cz, Fz and Pz. (3) No significant correlations were found among S2/S1 ratio, S1-S2, 100 (1-S2/S1) of sensory gating and PANSS (>0.05) in schizophrenic group. The first onset schizophrenics had sensory gating deficits, which could be quantified by P50.

关键词： anterior     Positive     S2-P50     schizophrenic     EMG/EP    

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NETO2 promotes melanoma progression via activation of the Ca/CaMKII signaling pathway

《医学前沿（英文）》 2023年 第17卷 第2期   页码 263-274 doi: 10.1007/s11684-022-0935-0

摘要： Melanoma is the most aggressive cutaneous tumor. Neuropilin and tolloid-like 2 (NETO2) is closely related to tumorigenesis. However, the functional significance of NETO2 in melanoma progression remains unclear. Herein, we found that NETO2 expression was augmented in melanoma clinical tissues and associated with poor prognosis in melanoma patients. Disrupting NETO2 expression markedly inhibited melanoma proliferation, malignant growth, migration, and invasion by downregulating the levels of calcium ions (Ca2+) and the expression of key genes involved in the calcium signaling pathway. By contrast, NETO2 overexpression had the opposite effects. Importantly, pharmacological inhibition of CaMKII/CREB activity with the CaMKII inhibitor KN93 suppressed NETO2-induced proliferation and melanoma metastasis. Overall, this study uncovered the crucial role of NETO2-mediated regulation in melanoma progression, indicating that targeting NETO2 may effectively improve melanoma treatment.

关键词： melanoma     neuropilin and tolloid-like 2     Ca2+/CaMKII signaling pathway    

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Achievements in burn surgery over the past 50 years in China

WANG Shiliang

《医学前沿（英文）》 2008年 第2卷 第4期   页码 332-336 doi: 10.1007/s11684-008-0063-5

摘要： This paper reflects on the advancements of clinical and scientific research in the field of burn surgery in China. It includes emergency care of massive burns, resuscitation, anti-infection, prevention and cure of internal organ injuries, metabolic and nutritional support, wound repair and rehabilitation, and special types of burns; it also covers pathology, microbiology, immunology, cell biology, molecular biology, and tissue engineering.

关键词： immunology     scientific     nutritional     microbiology     engineering    

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Berberine alleviates myocardial diastolic dysfunction by modulating Drp1-mediated mitochondrial fission and Ca

《医学前沿（英文）》 doi: 10.1007/s11684-023-0983-0

摘要： Berberine alleviates myocardial diastolic dysfunction by modulating Drp1-mediated mitochondrial fission and Ca homeostasis in a murine model of HFpEF

关键词： mitochondrial fission Ca     Berberine alleviates myocardial     murine model HFpEF    

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人工智能破解生物学50年来的一个重大挑战

Sean O´Neill

《工程（英文）》 2021年 第7卷 第6期   页码 706-708 doi: 10.1016/j.eng.2021.04.003

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Effect of K and Ca on catalytic activity of Mn-CeO

Boxiong SHEN, Lidan DENG, Jianhong CHEN

《环境科学与工程前沿（英文）》 2013年 第7卷 第4期   页码 512-517 doi: 10.1007/s11783-013-0519-y

摘要： Mn-CeO /Ti-pillared clay (PILC) is an attractive catalyst for selective catalytic reduction of NO at low temperature because of its low cost. The poisoning of K and Ca on the catalyst of Mn-CeO /Ti-PILC is an important problem because K and Ca are always in presence in flue gas. To investigate the effect of K and Ca on the physicochemical characters of the catalysts, the techniques of NH -temperature programmed desorption (TPD), H -temperature programmed reduction (TPR), and X-ray photoelectron spectroscopy (XPS) were used to analyze the fresh and deactivated catalysts of Mn-CeO /Ti-PILC. (Ca)Mn-CeO /Ti-PILC and (K)Mn-CeO /Ti-PILC are denoted for the dopes of the catalyst of Mn-CeO /Ti-PILC with Ca and K, respectively. The activities of Mn-CeO /Ti-PILC, (Ca)Mn-CeO /Ti-PILC and (K)Mn-CeO /Ti-PILC for NH -selective catalytic reduction (SCR) reaction at low temperature were investigated. The results showed that with the dopes of K and Ca on the catalysts, the SCR activities of the catalysts decreased greatly, and K exhibited more poisoning effect than Ca. With the dopes of K and Ca, the acidity, the redox property and chemisorbed oxygen on the surfaces of the catalysts were decreased, which resulted in a decreasing in SCR activity.

关键词： Mn-CeOx/Ti-pillared clay (PILC)     low-temperature selective catalytic reduction (SCR)     K and Ca poisoning effect    

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Protective roles of heat stress on the neurons in hippocampal CA1 region of mice

WANG Chunxu, WANG Hanxing

《医学前沿（英文）》 2007年 第1卷 第4期   页码 418-422 doi: 10.1007/s11684-007-0082-7

摘要： The effects of heat stress on the neurons in hippocampal CA1 region of brain ischemia/reperfusion were explored. The mice were pretreated with heat stress followed by ischemia/reperfusion by clipping bilateral cervical commo n arteries for 7 min. Mice were divided randomly into four groups as follows: (1) normal control group; (2) heat stress pretreated subsequent to ischemia/reperfusion group (HS/IR); (3) ischemia/reperfusion group (IR); and (4) heat stress group (HS). Animals in the last three groups were subdivided into three subgroups: 1 d, 4 d, 14 d respectively. The Morris water maze was used to test the ability of learning and memorizing, Nissl staining was used to count the average number of survived neurons in hippocampal CA1 region, and immunohistochemistry combined with image analysis system to detect the changes of Microtubule associated protein 2 (MAP-2) expression. The results showed that mice in IR group exhibited increased escape latency when compared with that of normal, HS and HS/IR groups (<0.01), and the mice in IR group adopted an inefficient search strategy, major in circling and restricted searching manners. Nissl staining results showed a significant reduction in the number of pyramidal neurons in hippocampal CA1 regions in HS/IR and IR groups, with a decrease in IR group (<0.01). Compared with normal group, the expression of MAP-2 in hippocampal CA1 region obviously decreased in IR group (<0.05). The present results indicate that heat stress pretreatment can improve the spatial learning and memorizing function through protection to hippocampal neurons.
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MSWNet: A visual deep machine learning method adopting transfer learning based upon ResNet 50 for municipal

《环境科学与工程前沿（英文）》 2023年 第17卷 第6期 doi: 10.1007/s11783-023-1677-1

摘要：

● MSWNet was proposed to classify municipal solid waste.

关键词： Municipal solid waste sorting     Deep residual network     Transfer learning     Cyclic learning rate     Visualization    

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Laboratory study on high-temperature adsorption of HCl by dry-injection of Ca(OH)

Junjun TAN,Guohua YANG,Jingqiao MAO,Huichao DAI

《环境科学与工程前沿（英文）》 2014年 第8卷 第6期   页码 863-870 doi: 10.1007/s11783-013-0618-9

摘要： Combustion-generated hydrogen chloride (HCl) is considered to be a very hazardous acid gaseous pollutant. This paper presents a laboratory study on the dry adsorption of HCl. The experiments were conducted in a dual-layer granular bed filter, at gas temperatures of 500°C–700°C and (Ca)/ (Cl)molar ratios of 1.0–5.0 using the silver nitrate titration method by dry adsorbent powders Ca(OH) . Mainly, the adsorption efficiency of HCl and utilization efficiency of Calcium were studied, by varying relevant factors including (Ca)/ (Cl), temperature, feeding method, water vapor and CO . With a relatively higher HCl concentration of 1000 ppm, the experimental results revealed that 600°C may be the optimum temperature for HCl adsorption when optimum (Ca)/ (Cl) was 2.5 in our tests. The results also demonstrated that the feeding at a constant pressure was more effective, and the HCl adsorption efficiency could rapidly reach over 90% with (Ca)/ (Cl) = 2.5 at 600°C. Furthermore, the HCl adsorption efficiency was found to be slightly promoted by water vapor, while could be impeded by CO , and the utilization efficiency of calcium could be up to 74.4% without CO , while was only 36.8% with CO when (Ca)/ (Cl) was 2.5 at 600°C.

关键词： acid gas HCl     Ca(OH)2     dry adsorption     high temperature     dual-layer granular bed filter    

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Clinical characteristics in lymphangioleiomyomatosis-related pulmonary hypertension: an observation on 50

Xiuxiu Wu, Wenshuai Xu, Jun Wang, Xinlun Tian, Zhuang Tian, Kaifeng Xu

《医学前沿（英文）》 2019年 第13卷 第2期   页码 259-266 doi: 10.1007/s11684-018-0634-z

摘要： Lymphangioleiomyomatosis (LAM) is a rare diffuse cystic lung disease. Knowledge on LAM-related pulmonary hypertension (PH) is limited. This study aimed to analyze the clinical characteristics of LAM with elevated pulmonary artery pressure (PAP) and evaluate the potential efficacy of sirolimus. The study involved 50 LAM patients who underwent echocardiography. According to the tricuspid regurgitation velocity (TRV), these patients were divided into the TRV≤2.8 m/s group and TRV>2.8 m/s group. Both groups comprised 25 females with an average age of 38.6±8.1 and 41.5±8.9 years. In the TRV>2.8 m/s group, the estimated systolic PAP (SPAP) was significantly elevated (52.08±12.45 mmHg vs. 30.24±5.25mmHg, <0.01). Linear analysis showed that SPAP was correlated with forced expiratory volume in 1 s (FEV ), diffusing capacity of the lungs for carbon monoxide, alveolar arterial oxygen gradient (P O ), and 6 min walking distance ( = −0.392, −0.351, 0.450, and −0.591, respectively; <0.05), in which P O was a risk factor for SPAP elevation ( = 0.064, OR= 1.066, <0.05). Moreover, in 10 patients who received sirolimus therapy, SPAP decreased from 57.0±12.6 mmHg to 35.2±11.1 mmHg. The study showed that LAM patients with PH exhibit poor pulmonary function and hypoxemia and may benefit from sirolimus treatment.

关键词： lymphangioleiomyomatosis     pulmonary hypertension     pulmonary function     hypoxemia     sirolimus    

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面向客户需求的产品优化设计方法研究

李汝鹏,魏巍,周峰,邹成

《中国工程科学》 2018年 第20卷 第2期   页码 33-41 doi: 10.15302/J-SSCAE-2018.02.006

摘要： 本文提出了一种快速响应客户需求的产品优化设计方法，通过基于模糊相似理论的需求信息模糊聚类方法，对具有模糊性和多样性的原始客户需求信息进行精简分类处理，以获取客户需求集合；然后构建了一种综合联合分析法（CA）和质量功能展开（QFD）的全新CA-QFD需求转化方法，从客户需求到产品设计属性进行精确转化，并通过对实例产品的优化设计，实现快速响应客户需求；最后，通过锻压机主工作液压缸的优化设计实例，验证了本文方法的可行性和适用性

关键词： 快速响应客户需求     模糊聚类     需求转化     CA-QFD方法     产品优化设计    

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基于大气阻力的立方星编队飞行非线性规划控制算法 Article

Sheng-chao DENG, Tao MENG, Zhong-he JIN

《信息与电子工程前沿（英文）》 2017年 第18卷 第7期   页码 867-881 doi: 10.1631/FITEE.1500493

摘要： 本文提出一种通过大气阻力实现轨道面内沿迹跟飞编队的综合策略，并将用于浙江大学下一颗皮纳卫星（该卫星是国际QB50项目成员之一）。QB50项目主要任务是90–300 km高度近地大气层探测。在这一轨道高度，大气阻力对卫星姿态和轨道的影响均不能忽略。

关键词： QB50；ZJUCubeSat；大气阻力；编队飞行    

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Phase equilibrium of the ternary system of NH 4 Cl—CaCl 2 —H 2 O at 50°C

Xia LI, Junsheng YUAN, Zhiyong JI, Jianxin CHEN,

《化学科学与工程前沿（英文）》 2010年 第4卷 第1期   页码 75-77 doi: 10.1007/s11705-009-0296-0

摘要： The equilibrium data on the ternary system of NHCl—CaCl—HO at 50°C were investigated using the wet-residue method. The experimental results show that there are three pure phase crystal areas of NHCl, 2NHCl·CaCl·3HO and CaCl·2HO, two mixture phase crystal areas of NHCl and 2NHCl·CaCl·3HO, and 2NHCl·CaCl·3HO and CaCl·2HO in the system. A new hydration double salt (2NHCl·CaCl·3HO) was found in the ternary equilibrium system for the first time.
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虚实融合的协同工作环境CAR-CA工程技术研究进展

赵沁平

《中国工程科学》 2009年 第11卷 第10期   页码 25-31

摘要： 面向我国自行设计生产商用大飞机的需求，在863计划支持下，正在研制用于驾驶舱布局设计和飞机关键部件辅助拆装维护的虚 实融合协同工作环境CAR-CA（collaborative augmented reality概要介绍CAR-CA的工程技术研究进展，包括体系结构、系统组成、关键技术研究和系统的应用前景等。

关键词： 虚实融合     协同工作     驾驶舱     设计     维护    

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标题 作者 时间 类型 操作

Numerical study of EGR effects on reducing the pressure rise rate of HCCI engine combustion

Gen CHEN, Norimasa IIDA, Zuohua HUANG,

期刊论文

P50 auditory sensory gating in first onset schizophrenics and normal healthy adults

WANG Hongxing, ZHANG Mingdao, CHEN Xingshi, LOU Feiying, LIANG Jianhua, CHEN Chong, SHI Tiantao, LU Qiulin

期刊论文

NETO2 promotes melanoma progression via activation of the Ca/CaMKII signaling pathway

期刊论文

Achievements in burn surgery over the past 50 years in China

WANG Shiliang

期刊论文

Berberine alleviates myocardial diastolic dysfunction by modulating Drp1-mediated mitochondrial fission and Ca

期刊论文

人工智能破解生物学50年来的一个重大挑战

Sean O´Neill

期刊论文

Effect of K and Ca on catalytic activity of Mn-CeO

Boxiong SHEN, Lidan DENG, Jianhong CHEN

期刊论文

Protective roles of heat stress on the neurons in hippocampal CA1 region of mice

WANG Chunxu, WANG Hanxing

期刊论文

MSWNet: A visual deep machine learning method adopting transfer learning based upon ResNet 50 for municipal

期刊论文

Laboratory study on high-temperature adsorption of HCl by dry-injection of Ca(OH)

Junjun TAN,Guohua YANG,Jingqiao MAO,Huichao DAI

期刊论文

Clinical characteristics in lymphangioleiomyomatosis-related pulmonary hypertension: an observation on 50

Xiuxiu Wu, Wenshuai Xu, Jun Wang, Xinlun Tian, Zhuang Tian, Kaifeng Xu

期刊论文

面向客户需求的产品优化设计方法研究

李汝鹏,魏巍,周峰,邹成

期刊论文

基于大气阻力的立方星编队飞行非线性规划控制算法

Sheng-chao DENG, Tao MENG, Zhong-he JIN

期刊论文

Phase equilibrium of the ternary system of NH 4 Cl—CaCl 2 —H 2 O at 50°C

Xia LI, Junsheng YUAN, Zhiyong JI, Jianxin CHEN,

期刊论文

虚实融合的协同工作环境CAR-CA工程技术研究进展

赵沁平

期刊论文